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The map label for this gene is gatR

Identifier: 218695709

GI number: 218695709

Start: 2399861

End: 2400640

Strand: Reverse

Name: gatR

Synonym: EC55989_2344

Alternate gene names: 218695709

Gene position: 2400640-2399861 (Counterclockwise)

Preceding gene: 218695710

Following gene: 218695707

Centisome position: 46.57

GC content: 47.31

Gene sequence:

>780_bases
ATGACGATGAATTCATTCGAGCGAAGGAATAAGATCATCCAATTAGTGAATGAACAGGGAACCGTGCTTGTTCAGGATCT
GGCGGGAGTATTTGCTGCCTCGGAAGCGACAATCCGTGCCGATTTGCGCTTTCTCGAACAAAAAGGCGTGGTTACGCGCT
TTCATGGCGGTGCGGCGAAAATAATGTCCGGTAATAGTGAAACCGAGACCCAGGAAGTCGGGTTTAAAGAGCGATTTCAG
CTCGCCAGCGCGCCAAAAAACAGAATAGCGCAGGCGGCAGTCAAAATGATCCACGAAGGGATGACCGTTATTCTCGACAG
CGGAAGTACGACGATGCTTATCGCCGAAGGATTAATGACCGCCAAAAATATCACGGTGATTACCAACAGTCTCCCGGCAG
CGTTTGCCCTTTCCGAAAATAAAGACATTACTCTGGTCGTCTGCGGTGGCACGGTCCGCCATAAAACGCGCTCGATGCAT
GGTTCCATTGCCGAGCGTTCATTGCAGGATATTAATGCCGATTTAATGTTTGTCGGTGCTGATGGTATTGATGCGGTTAA
TGGTATTACGACCTTTAATGAAGGTTATTCGATTAGCGGGGCGATGGTCACCGCCGCTAATAAAGTGATTGCCGTTCTCG
ATTCATCGAAATTTAACCGTCGCGGTTTTAATCAGGTACTGCCAATCGAAAAAATTGACATTATTATTACCGATGATGCT
GTGTCTGAGGTGGATAAACTGGCATTGCAGAAGACACGGGTAAAATTAATTACGGTGTAG

Upstream 100 bases:

>100_bases
AAACCGCGGGCCAGCGTGATGCTGGCCCGGTATTGTGCAAAACAGATCATTCACCAATGGTCCCCCTTCGTTTACACTAG
CCACAATTGAATATGGGTAA

Downstream 100 bases:

>100_bases
TATTGTTCTGTATGCCGGATAAGGTATTTACACTGCATCCGGCATTTCGGATTCTCCCTGGTTCAAGAGAGAATAGTTTG
ATTAACGCAATAATGGACAA

Product: Galactitol utilization operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQ
LASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMH
GSIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDA
VSEVDKLALQKTRVKLITV

Sequences:

>Translated_259_residues
MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQ
LASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMH
GSIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDA
VSEVDKLALQKTRVKLITV
>Mature_258_residues
TMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQL
ASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHG
SIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDAV
SEVDKLALQKTRVKLITV

Specific function: Repressor of the gat operon for galacticol transport and metabolism

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=37.7952755905512, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI1789059, Length=256, Percent_Identity=39.0625, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI226510968, Length=256, Percent_Identity=31.25, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788069, Length=237, Percent_Identity=32.4894514767932, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787540, Length=259, Percent_Identity=29.7297297297297, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789829, Length=237, Percent_Identity=29.1139240506329, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=28.755364806867, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787063, Length=253, Percent_Identity=24.901185770751, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790753, Length=261, Percent_Identity=25.2873563218391, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790635, Length=242, Percent_Identity=26.8595041322314, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GATR_ECOLI (P36930)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   X79837
- EMBL:   D12598
- EMBL:   X64217
- EMBL:   X64218
- ProteinModelPortal:   P36930
- EchoBASE:   EB2081
- EcoGene:   EG12162
- BioCyc:   EcoCyc:PD00338
- BioCyc:   EcoCyc:PD02366
- Genevestigator:   P36930
- GO:   GO:0005622
- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00037
- SMART:   SM00420

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR

EC number: NA

Molecular weight: Translated: 27960; Mature: 27828

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00894 HTH_DEOR_1; PS51000 HTH_DEOR_2; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAK
CCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCEEE
IMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMT
EECCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCHHC
AKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGSIAERSLQDINADLMFVGA
CCCEEEEECCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
DGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDA
CCCCHHCCEEECCCCCEECCEEEEECCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECHH
VSEVDKLALQKTRVKLITV
HHHHHHHHHHHHCEEEEEC
>Mature Secondary Structure 
TMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAK
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCEEE
IMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMT
EECCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCHHC
AKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGSIAERSLQDINADLMFVGA
CCCEEEEECCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
DGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDA
CCCCHHCCEEECCCCCEECCEEEEECCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECHH
VSEVDKLALQKTRVKLITV
HHHHHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 7772602; 1661252