BacMap

Definition	Escherichia coli 55989, complete genome.
Accession	NC_011748
Length	5,154,862

Click here to switch to the map view.

The map label for this gene is yeaE

Identifier: 218695340

GI number: 218695340

Start: 2013215

End: 2014069

Strand: Reverse

Name: yeaE

Synonym: EC55989_1950

Alternate gene names: 218695340

Gene position: 2014069-2013215 (Counterclockwise)

Preceding gene: 218695341

Following gene: 218695337

Centisome position: 39.07

GC content: 50.99

Gene sequence:

>855_bases
ATGCAACAAAAAATGATTCAATTTAGTGGCGATGTCTCACTGCCAGCCATAGGGCAGGGAACATGGTATATGGGCGAAGA
TGCCAGTCAGCGCAAAACAGAAGTTGCTGCACTACGCGCGGGCATTGAGCTCGGTTTAACCCTCATTGATACCGCCGAAA
TGTATGCCGATGGCGGTGCCGAAAAGGTGGTTGGGGAAGCATTAACCGGTCTGCGCGATAACGTCTTTCTCGTCTCTAAA
GTCTATCCGTGGAATGCTGGCGGGCAAAAAGCGATAAATGCATGCGAAGCCAGTTTACGCCGTCTCAATACTGATTATCT
CGATCTCTACTTATTACACTGGTCTGGCAGTTTCGCTTTTGAAGAGACTGTGGCAGCGATGGAAAAATTGATCGCCCAGG
GAAAAATCCGCCGCTGGGGCGTTTCTAACCTTGATCATGCTGATATGCAGGAACTCTGGCAGCTGCCGGGGGGAAATCAG
TGTGCCACTAATCAGGTGCTTTACCATCTCGGTTCACGAGGGATTGAGTACGATCTACTCCCCTGGTGCCAGCAACAGCA
GATGCCGGTGATGGCTTACAGTCCATTAGCCCAGGCCGGGCGGTTGCGCAATGGACTGTTAAAAAACGCGGTAGTCAACG
AAATTGCACATGCTCACAATATCAGCGCGGCACAAGTATTGTTGGCGTGGGTAATCAGCCATCAGGGTGTGATGGCGATT
CCAAAAGCGGCCACGATTGCCCATGTCCAACAGAATGCGGCTGTGCTTGAGGTCGAACTTTCGTCAGCGGAATTAACCAT
GCTGGATAAAGCGTATCCGGCACCAAAAGGAAAAACTGCGCTGGATATGGTGTGA

Upstream 100 bases:

>100_bases
ACAAATTCTGATAATGCATCTTTCCAGGGCATTTTGTGCATAAAAACAGGGCGTCACGCCCTGTTTTGCATTACGGTGGT
GCAATACCTGGGAGGAAACA

Downstream 100 bases:

>100_bases
TGTTGATACGTGCCGGATGCATCGCACCCGGCACACAACATTAACGCAAATTAACGTTTCGCAACGCGAATGGATTGCGC
CAGATGTGCAGGTTTCTCTT

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDHADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV

Sequences:

>Translated_284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDHADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV
>Mature_284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDHADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=297, Percent_Identity=29.6296296296296, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=30.5660377358491, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI93277124, Length=305, Percent_Identity=27.5409836065574, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI24497577, Length=290, Percent_Identity=28.6206896551724, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI5174391, Length=290, Percent_Identity=28.6206896551724, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI5174695, Length=302, Percent_Identity=27.4834437086093, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI310109922, Length=275, Percent_Identity=29.0909090909091, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI300116273, Length=288, Percent_Identity=28.4722222222222, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI4502049, Length=291, Percent_Identity=30.2405498281787, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI300116271, Length=281, Percent_Identity=27.7580071174377, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI45446745, Length=295, Percent_Identity=27.4576271186441, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4503285, Length=295, Percent_Identity=27.4576271186441, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI310109920, Length=295, Percent_Identity=27.4576271186441, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI24497585, Length=290, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5453543, Length=295, Percent_Identity=26.7796610169492, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI24497583, Length=291, Percent_Identity=26.8041237113402, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223718702, Length=200, Percent_Identity=32, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=98.2394366197183, Blast_Score=576, Evalue=1e-166,
Organism=Escherichia coli, GI1786400, Length=261, Percent_Identity=28.735632183908, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788070, Length=313, Percent_Identity=27.4760383386581, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081735, Length=301, Percent_Identity=28.2392026578073, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082198, Length=257, Percent_Identity=28.7937743190661, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=27.6353276353276, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789375, Length=323, Percent_Identity=24.1486068111455, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787674, Length=259, Percent_Identity=23.5521235521236, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI48994888, Length=235, Percent_Identity=30.6382978723404, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17561298, Length=285, Percent_Identity=31.9298245614035, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17552492, Length=273, Percent_Identity=30.03663003663, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=30.3249097472924, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17564128, Length=307, Percent_Identity=27.3615635179153, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17537077, Length=297, Percent_Identity=29.6296296296296, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17537075, Length=297, Percent_Identity=29.6296296296296, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17538386, Length=290, Percent_Identity=29.3103448275862, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561300, Length=293, Percent_Identity=28.6689419795222, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17566692, Length=299, Percent_Identity=25.0836120401338, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17550248, Length=297, Percent_Identity=23.9057239057239, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324694, Length=293, Percent_Identity=27.6450511945392, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320079, Length=291, Percent_Identity=27.4914089347079, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6322556, Length=283, Percent_Identity=26.5017667844523, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323998, Length=305, Percent_Identity=24.9180327868852, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=24.4897959183673, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644950, Length=312, Percent_Identity=31.7307692307692, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI221378297, Length=332, Percent_Identity=30.421686746988, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=24.4827586206897, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24657054, Length=289, Percent_Identity=25.6055363321799, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24663317, Length=299, Percent_Identity=22.742474916388, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281366140, Length=252, Percent_Identity=25.3968253968254, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24662789, Length=309, Percent_Identity=26.2135922330097, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI20129731, Length=297, Percent_Identity=24.9158249158249, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356425, Length=298, Percent_Identity=23.1543624161074, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24662781, Length=288, Percent_Identity=26.0416666666667, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24662785, Length=290, Percent_Identity=25.8620689655172, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30977; Mature: 30977

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHCCCH
EKVVGEALTGLRDNVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAF
HHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
EETVAAMEKLIAQGKIRRWGVSNLDHADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEC
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV
CCHHHHHHHHCCCEEEEEEECCCCEEEHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHCCCH
EKVVGEALTGLRDNVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAF
HHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
EETVAAMEKLIAQGKIRRWGVSNLDHADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEC
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV
CCHHHHHHHHCCCEEEEEEECCCCEEEHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]