Click here to switch to the map view.

The map label for this gene is orn [H]

Identifier: 218692499

GI number: 218692499

Start: 4909384

End: 4909929

Strand: Direct

Name: orn [H]

Synonym: ECED1_4949

Alternate gene names: 218692499

Gene position: 4909384-4909929 (Clockwise)

Preceding gene: 218692495

Following gene: 218692501

Centisome position: 94.24

GC content: 53.85

Gene sequence:

>546_bases
ATGAGTGCCAATGAAAACAACCTGATTTGGATCGATCTTGAGATGACCGGTCTGGATCCCGAGCGCGATCGCATTATTGA
GATTGCCACGCTGGTGACCGATGCCAACCTGAATATTCTGGCAGAAGGGCCGACCATTGCAGTACATCAGTCCGATGAAC
AGCTGGCGCTGATGGATGACTGGAACGTGCGCACCCATACCGCCAGCGGGCTGGTAGAGCGTGTGAAAGCGAGCACGATG
GGCGATCGTGAAGCTGAACTGGCAACGCTCGAATTCTTAAAACAGTGGGTGCCTGCGGGAAAATCGCCGATTTGTGGTAA
CAGCATCGGTCAGGACCGTCGCTTCCTGTTTAAATACATGCCGGAGCTGGAAGCCTACTTCCACTACCGCTATCTCGATG
TTAGCACCCTGAAAGAGCTGGCGCGCCGCTGGAAGCCGGAAATTCTTGACGGCTTTACCAAGCAGGGGACGCATCAGGCG
ATGGATGATATCCGTGAATCGGTGGCGGAGTTGGCTTACTACCGCGAGCATTTTATCAAGCTGTAA

Upstream 100 bases:

>100_bases
ACTCAATCGTACAGACTCCTGGTCGCCCCTGATGGGCAAAACATCTATGATACACGCAATTGTGGATCAATATAGTCACT
GTGAATGGGTGGAAAATAGC

Downstream 100 bases:

>100_bases
AATTTTTCCTGGTCACGTAAGCGCCGGAATCCACTTGCGGCGGCGTGATTTTGACGCTAAATTGAACGTCTTGCTGATAA
TTTCAGCACTTGAGATAAAA

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTM
GDREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
MDDIRESVAELAYYREHFIKL

Sequences:

>Translated_181_residues
MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTM
GDREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
MDDIRESVAELAYYREHFIKL
>Mature_180_residues
SANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMG
DREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQAM
DDIRESVAELAYYREHFIKL

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides [H]

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI224496106, Length=183, Percent_Identity=48.6338797814208, Blast_Score=184, Evalue=5e-47,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=100, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17557752, Length=177, Percent_Identity=49.7175141242938, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=182, Percent_Identity=35.1648351648352, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355135, Length=177, Percent_Identity=45.7627118644068, Blast_Score=183, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20816; Mature: 20685

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDD
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHEECCCCEEEECCCEEEEECCCCCEEEEEC
WNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYM
CCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQAMDDIRESVAELAYYREHFIK
HHHHHHHHHHEECHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure 
SANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDD
CCCCCCEEEEEEEEECCCCCHHHHHHHHHHEECCCCEEEECCCEEEEECCCCCEEEEEC
WNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYM
CCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQAMDDIRESVAELAYYREHFIK
HHHHHHHHHHEECHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA