Click here to switch to the map view.

The map label for this gene is dctD [H]

Identifier: 218692343

GI number: 218692343

Start: 4737283

End: 4738641

Strand: Reverse

Name: dctD [H]

Synonym: ECED1_4778

Alternate gene names: 218692343

Gene position: 4738641-4737283 (Counterclockwise)

Preceding gene: 218692344

Following gene: 218692334

Centisome position: 90.96

GC content: 44.52

Gene sequence:

>1359_bases
ATGAATAATAAATCCAGTGAAATTACTATAGTTTATATTGAAGATAGTGACGATGTACGTTTTGCCTGTGAACAAACGCT
CACGCTGGCTGGTTATCGTGTTATTTCCTGTTGCGATGCAGAACACAGTATTCCCCTTATTCAAAGTCAGGCCAACATTA
TTATACTGACCGATGTCAGGTTACCTGGAATATCAGGACTAGAGCTCCTCAGTTACATCAACGAAATGGATAGCAAAATT
CCGGTTATTTTAATTACCGGACACGGTGACGTGGAAATGGCGGTGGATGCCATGCGTAATGGTGCATTCGATTTCATTGA
GAAACCAAGTAGCTCAGATAAATTATTGAGTATTATTGCCAGAGCGGTAGAAAAACGGCGATTGGTTTTAGAAAATCAGC
AATTACTGGCGAATCTGCAACAGGAAAATGGCCCGGTGCTGATTGGTCGTAGTCCGCAGATGCAACAACTGCGTAAAATG
ATCCTTAATGTCGCAGATACCGGTGCCGATGTCCTTATTTATGGTGAAACAGGTTGTGGTAAAGAAGTCGTCGCCAGAAT
GCTGCATCACTGGAGTACCCGCCGTCAGGGGCAGTTTGTTGCCTTAAACTGTGCAGGCTTACCAGAAACGTTGTTTGAAA
GCGAAATATTTGGTCATGAGGCGGGCGCATTTACCGGTGCGGTTAAAAAGCGTATTGGAAAAATTGAACATGCAAATGGT
GGTACGTTATTTCTCGATGAAATAGAGGGAATGCCATCAGGAATGCAGGTAAAACTGCTACGTGTATTGCAGGAAAGAAC
CATTGAACGATTAGGTGCCAATCAATTAATTCCGGTGAATTGCCGTGTTATTGCAGCGACCAAGGAAGATTTACTGCGTC
GCAGCGAAGAACATCTGTTTCGTCTCGATCTCTATTATCGTCTGAATGTGGTTAGCCTGAATATTCCACCTCTACGCCAG
CGACGAGAAGATATCCCTGAACTGTTTTACTGGTTCGCCAGTCAGGCGGCACAAAAATATAATCGTCCTCTGCCTGATAT
TTCTCCCATGTTACTGGCCTGGTTGCAGTCACAAAGTTGGCCTGGCAATGTACGTGAACTTAAACACAATGCAGAGCGTT
TTGTTCTCGGTTTACTGACCCACCACCAGCCAGTGCCAATGACTCAGCAAGAAGAGAGTGGTCTTACCGCCTGCATTGAT
GCTTTCGAGAAAAAGTTAATCGAAGATATGCTGCGACAAACGGAAGGCCAGGTCAGTTTGACAGCGCGGCTATTACAGCT
GCCGCGCAAGACTTTATATGACAAACTCAACAAACATCAGATTCAACCGCAAGTTTATCGACCAGAATCATCCAGCTAA

Upstream 100 bases:

>100_bases
AGCGAAATTGTCCGAAATTCGAACGGCGCACTCCACGCCAGTAATCATCCTGAAGGCGGCGCAGTAATGACATTAACCTG
GCCTGAATGGGGAGAAGAAC

Downstream 100 bases:

>100_bases
TGCTGATTCCTGAGGATGTAACCCCAAATCGATACCTTTGCGGGCGTAATGTTCAACTACCCAGGACCAGAATGATACCG
GGATCGTAATCATCTTCGCA

Product: C4-dicarboxylate transport transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNNKSSEITIVYIEDSDDVRFACEQTLTLAGYRVISCCDAEHSIPLIQSQANIIILTDVRLPGISGLELLSYINEMDSKI
PVILITGHGDVEMAVDAMRNGAFDFIEKPSSSDKLLSIIARAVEKRRLVLENQQLLANLQQENGPVLIGRSPQMQQLRKM
ILNVADTGADVLIYGETGCGKEVVARMLHHWSTRRQGQFVALNCAGLPETLFESEIFGHEAGAFTGAVKKRIGKIEHANG
GTLFLDEIEGMPSGMQVKLLRVLQERTIERLGANQLIPVNCRVIAATKEDLLRRSEEHLFRLDLYYRLNVVSLNIPPLRQ
RREDIPELFYWFASQAAQKYNRPLPDISPMLLAWLQSQSWPGNVRELKHNAERFVLGLLTHHQPVPMTQQEESGLTACID
AFEKKLIEDMLRQTEGQVSLTARLLQLPRKTLYDKLNKHQIQPQVYRPESSS

Sequences:

>Translated_452_residues
MNNKSSEITIVYIEDSDDVRFACEQTLTLAGYRVISCCDAEHSIPLIQSQANIIILTDVRLPGISGLELLSYINEMDSKI
PVILITGHGDVEMAVDAMRNGAFDFIEKPSSSDKLLSIIARAVEKRRLVLENQQLLANLQQENGPVLIGRSPQMQQLRKM
ILNVADTGADVLIYGETGCGKEVVARMLHHWSTRRQGQFVALNCAGLPETLFESEIFGHEAGAFTGAVKKRIGKIEHANG
GTLFLDEIEGMPSGMQVKLLRVLQERTIERLGANQLIPVNCRVIAATKEDLLRRSEEHLFRLDLYYRLNVVSLNIPPLRQ
RREDIPELFYWFASQAAQKYNRPLPDISPMLLAWLQSQSWPGNVRELKHNAERFVLGLLTHHQPVPMTQQEESGLTACID
AFEKKLIEDMLRQTEGQVSLTARLLQLPRKTLYDKLNKHQIQPQVYRPESSS
>Mature_452_residues
MNNKSSEITIVYIEDSDDVRFACEQTLTLAGYRVISCCDAEHSIPLIQSQANIIILTDVRLPGISGLELLSYINEMDSKI
PVILITGHGDVEMAVDAMRNGAFDFIEKPSSSDKLLSIIARAVEKRRLVLENQQLLANLQQENGPVLIGRSPQMQQLRKM
ILNVADTGADVLIYGETGCGKEVVARMLHHWSTRRQGQFVALNCAGLPETLFESEIFGHEAGAFTGAVKKRIGKIEHANG
GTLFLDEIEGMPSGMQVKLLRVLQERTIERLGANQLIPVNCRVIAATKEDLLRRSEEHLFRLDLYYRLNVVSLNIPPLRQ
RREDIPELFYWFASQAAQKYNRPLPDISPMLLAWLQSQSWPGNVRELKHNAERFVLGLLTHHQPVPMTQQEESGLTACID
AFEKKLIEDMLRQTEGQVSLTARLLQLPRKTLYDKLNKHQIQPQVYRPESSS

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=39.514348785872, Blast_Score=306, Evalue=1e-84,
Organism=Escherichia coli, GI1790437, Length=420, Percent_Identity=39.5238095238095, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI1790299, Length=466, Percent_Identity=36.6952789699571, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1788905, Length=457, Percent_Identity=36.5426695842451, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI87082117, Length=330, Percent_Identity=44.5454545454545, Blast_Score=234, Evalue=6e-63,
Organism=Escherichia coli, GI1789087, Length=328, Percent_Identity=43.2926829268293, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1789233, Length=230, Percent_Identity=45.2173913043478, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87082152, Length=311, Percent_Identity=39.871382636656, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1786524, Length=256, Percent_Identity=43.75, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87081872, Length=283, Percent_Identity=40.6360424028269, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1787583, Length=227, Percent_Identity=40.5286343612335, Blast_Score=168, Evalue=7e-43,
Organism=Escherichia coli, GI87081858, Length=309, Percent_Identity=31.3915857605178, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789828, Length=256, Percent_Identity=35.9375, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51028; Mature: 51028

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKSSEITIVYIEDSDDVRFACEQTLTLAGYRVISCCDAEHSIPLIQSQANIIILTDVR
CCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCEEEEEECC
LPGISGLELLSYINEMDSKIPVILITGHGDVEMAVDAMRNGAFDFIEKPSSSDKLLSIIA
CCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHH
RAVEKRRLVLENQQLLANLQQENGPVLIGRSPQMQQLRKMILNVADTGADVLIYGETGCG
HHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
KEVVARMLHHWSTRRQGQFVALNCAGLPETLFESEIFGHEAGAFTGAVKKRIGKIEHANG
HHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCEECCC
GTLFLDEIEGMPSGMQVKLLRVLQERTIERLGANQLIPVNCRVIAATKEDLLRRSEEHLF
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECEEEEEECHHHHHHHHHHHEE
RLDLYYRLNVVSLNIPPLRQRREDIPELFYWFASQAAQKYNRPLPDISPMLLAWLQSQSW
EEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
PGNVRELKHNAERFVLGLLTHHQPVPMTQQEESGLTACIDAFEKKLIEDMLRQTEGQVSL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
TARLLQLPRKTLYDKLNKHQIQPQVYRPESSS
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
>Mature Secondary Structure
MNNKSSEITIVYIEDSDDVRFACEQTLTLAGYRVISCCDAEHSIPLIQSQANIIILTDVR
CCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCEEEEEECC
LPGISGLELLSYINEMDSKIPVILITGHGDVEMAVDAMRNGAFDFIEKPSSSDKLLSIIA
CCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHH
RAVEKRRLVLENQQLLANLQQENGPVLIGRSPQMQQLRKMILNVADTGADVLIYGETGCG
HHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
KEVVARMLHHWSTRRQGQFVALNCAGLPETLFESEIFGHEAGAFTGAVKKRIGKIEHANG
HHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCEECCC
GTLFLDEIEGMPSGMQVKLLRVLQERTIERLGANQLIPVNCRVIAATKEDLLRRSEEHLF
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECEEEEEECHHHHHHHHHHHEE
RLDLYYRLNVVSLNIPPLRQRREDIPELFYWFASQAAQKYNRPLPDISPMLLAWLQSQSW
EEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
PGNVRELKHNAERFVLGLLTHHQPVPMTQQEESGLTACIDAFEKKLIEDMLRQTEGQVSL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
TARLLQLPRKTLYDKLNKHQIQPQVYRPESSS
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]