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The map label for this gene is metJ [H]

Identifier: 218692222

GI number: 218692222

Start: 4579369

End: 4579824

Strand: Reverse

Name: metJ [H]

Synonym: ECED1_4640

Alternate gene names: 218692222

Gene position: 4579824-4579369 (Counterclockwise)

Preceding gene: 218692225

Following gene: 218692221

Centisome position: 87.91

GC content: 50.0

Gene sequence:

>456_bases
ATGCATTATCACGCCGACAGGTGCATTACACGATGTCACGGTAACGCCTGTACGGTAAACTATGCGGGTTTACGGTCAGT
ACCCATATTAATTGTGTGGTCTGGCCTCAATTTATTGACGAAGAGGATTAAGTATCTCATGGCTGAATGGAGCGGCGAAT
ATATCAGCCCATACGCTGAGCACGGCAAGAAGAGTGAACAAGTCAAAAAAATTACGGTTTCCATTCCTCTTAAGGTGTTA
AAAATCCTCACCGATGAACGCACGCGTCGTCAGGTGAACAACCTGCGTCACGCGACCAACAGCGAGCTGCTGTGCGAAGC
GTTTCTGCATGCCTTTACCGGGCAACCTTTGCCGGATGATGCCGACCTGCGTAAAGAGCGCAGCGACGAAATTCCGGAGG
CGGCAAAAGAGATCATGCGTGAGATGGGGATTAACCCGGAGACGTGGGAATACTAA

Upstream 100 bases:

>100_bases
GCACCAGAGTAAACATTGTGTTAATGGACGTCAATACATCTGGACATCTAAACTTCTTTGCGTATAGATTGAGCAAATCT
CAAATAGCCGTTAAAATTAT

Downstream 100 bases:

>100_bases
AGCGGAAAAGAGCGGCGCGGAGTTAACCAGCCGCTTTTTTCATACATGGACGTTTAACGATGAAAATCAGGCTACTGATT
CTCAGCCTGCTGGTTTCTGT

Product: transcriptional repressor protein MetJ

Products: NA

Alternate protein names: Met regulon regulatory protein metJ [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MHYHADRCITRCHGNACTVNYAGLRSVPILIVWSGLNLLTKRIKYLMAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVL
KILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY

Sequences:

>Translated_151_residues
MHYHADRCITRCHGNACTVNYAGLRSVPILIVWSGLNLLTKRIKYLMAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVL
KILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
>Mature_151_residues
MHYHADRCITRCHGNACTVNYAGLRSVPILIVWSGLNLLTKRIKYLMAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVL
KILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY

Specific function: This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis [H]

COG id: COG3060

COG function: function code KE; Transcriptional regulator of met regulon

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metJ family [H]

Homologues:

Organism=Escherichia coli, GI1790373, Length=105, Percent_Identity=100, Blast_Score=219, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002084
- InterPro:   IPR010985
- ProDom:   PD020365 [H]

Pfam domain/function: PF01340 MetJ [H]

EC number: NA

Molecular weight: Translated: 17395; Mature: 17395

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYHADRCITRCHGNACTVNYAGLRSVPILIVWSGLNLLTKRIKYLMAEWSGEYISPYAE
CCCCHHHHHHHHCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHH
HGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDD
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
ADLRKERSDEIPEAAKEIMREMGINPETWEY
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MHYHADRCITRCHGNACTVNYAGLRSVPILIVWSGLNLLTKRIKYLMAEWSGEYISPYAE
CCCCHHHHHHHHCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHH
HGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDD
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
ADLRKERSDEIPEAAKEIMREMGINPETWEY
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA