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The map label for this gene is hxlB [H]

Identifier: 218692106

GI number: 218692106

Start: 4453065

End: 4453655

Strand: Direct

Name: hxlB [H]

Synonym: ECED1_4515

Alternate gene names: 218692106

Gene position: 4453065-4453655 (Clockwise)

Preceding gene: 218692105

Following gene: 218692107

Centisome position: 85.48

GC content: 49.07

Gene sequence:

>591_bases
GTGTTTGAGAAAAATTATTTCATGAGGTGTGAAATGGACGCAAAGCTGTACATCACTGAGATCATCAATGAATTAACCTT
CGTTAAGGACTCTATCCGTGAGGATGACTGCACCAAATTGATCGACGCTATTCAGCAAAGCCAGCGCGTTTTCTGCTATG
GCCTGGGACGTGCCGGCTTTTCCATGAAAGCCTTCACCATGCGCCTGATGCATATGGGAAAAGAGGTTTACTTCCTGACG
GAAACCATTACGCCGAACTTTGGGCCTGGCGATCTGTTTATCGTTTCTTCCGCTTCCGGTGAGACAGCACAACTGGTGGC
ACTGGCGAAAAAAGCACGTCAGCTTGGCGGCGCTGTGGCGGTGTTAACCACGAATCGACACGCCACTATCACCGAGTTTG
TCGATGTCATCGTGCAAATTAATGCCCCTTCCAAAAATCAAAAAGATTCTGTTTTCCGCTCGGCACAGCCGATGGCGTCG
TTGTATGAGCAAGCTTTGCTGGTGATTGCCGATGCATTAGTGATGAAGATGGCTGCTGAAAGTGGTGCGCCGGAAAGTGA
ACTGTTTAAGCGCCACGCCAATCTGGAATAG

Upstream 100 bases:

>100_bases
TGTTTTTTAATGAAAAACATATCAACCTATGATCTTTCTTGTGACTAGCTTCACATTTCATACTGATGCATTGGAATGAA
ATAAAATTTCATGAGATTTT

Downstream 100 bases:

>100_bases
TCGTCGCCGTTATTTGCTCGATACCCTACAGGAGAATAAAAATGAGCAAAAAAATAACATCCTTGTTTAACTTCAAGAAG
TTGCAGAAATTTTCTTCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: 6-phospho-3-hexuloisomerase; PHI [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MFEKNYFMRCEMDAKLYITEIINELTFVKDSIREDDCTKLIDAIQQSQRVFCYGLGRAGFSMKAFTMRLMHMGKEVYFLT
ETITPNFGPGDLFIVSSASGETAQLVALAKKARQLGGAVAVLTTNRHATITEFVDVIVQINAPSKNQKDSVFRSAQPMAS
LYEQALLVIADALVMKMAAESGAPESELFKRHANLE

Sequences:

>Translated_196_residues
MFEKNYFMRCEMDAKLYITEIINELTFVKDSIREDDCTKLIDAIQQSQRVFCYGLGRAGFSMKAFTMRLMHMGKEVYFLT
ETITPNFGPGDLFIVSSASGETAQLVALAKKARQLGGAVAVLTTNRHATITEFVDVIVQINAPSKNQKDSVFRSAQPMAS
LYEQALLVIADALVMKMAAESGAPESELFKRHANLE
>Mature_196_residues
MFEKNYFMRCEMDAKLYITEIINELTFVKDSIREDDCTKLIDAIQQSQRVFCYGLGRAGFSMKAFTMRLMHMGKEVYFLT
ETITPNFGPGDLFIVSSASGETAQLVALAKKARQLGGAVAVLTTNRHATITEFVDVIVQINAPSKNQKDSVFRSAQPMAS
LYEQALLVIADALVMKMAAESGAPESELFKRHANLE

Specific function: Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate. Together with hxlA, may act as a formaldehyde detoxification system [H]

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017552
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.27 [H]

Molecular weight: Translated: 21821; Mature: 21821

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKNYFMRCEMDAKLYITEIINELTFVKDSIREDDCTKLIDAIQQSQRVFCYGLGRAGF
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCCC
SMKAFTMRLMHMGKEVYFLTETITPNFGPGDLFIVSSASGETAQLVALAKKARQLGGAVA
HHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEE
VLTTNRHATITEFVDVIVQINAPSKNQKDSVFRSAQPMASLYEQALLVIADALVMKMAAE
EEECCCCCHHHHHHHHHEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SGAPESELFKRHANLE
CCCCHHHHHHHHCCCC
>Mature Secondary Structure
MFEKNYFMRCEMDAKLYITEIINELTFVKDSIREDDCTKLIDAIQQSQRVFCYGLGRAGF
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCCC
SMKAFTMRLMHMGKEVYFLTETITPNFGPGDLFIVSSASGETAQLVALAKKARQLGGAVA
HHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEE
VLTTNRHATITEFVDVIVQINAPSKNQKDSVFRSAQPMASLYEQALLVIADALVMKMAAE
EEECCCCCHHHHHHHHHEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SGAPESELFKRHANLE
CCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 7921238 [H]