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The map label for this gene is bglF [H]

Identifier: 218692010

GI number: 218692010

Start: 4340620

End: 4342569

Strand: Reverse

Name: bglF [H]

Synonym: ECED1_4412

Alternate gene names: 218692010

Gene position: 4342569-4340620 (Counterclockwise)

Preceding gene: 218692011

Following gene: 218692009

Centisome position: 83.36

GC content: 50.05

Gene sequence:

>1950_bases
TTGCTTGATTCACGTCAGGCCGTTTTTTTCAGGTTTTTTTTTGGAGTTTTGCCGCAAAGCGGTAGAGGGCAAGTTATGAC
GGAGTTAGCCAGAACAATAGTCGCAGGAGTCGGGGGCGCAGATAACATTGTGAGTCTGATGCATTGTGCAACGCGATTAC
GTTTTAAGTTAAAGGATGAAAGCAAAGCGCAAGCTGAGGTACTGAAAAAGACCCCCGGTATTATTATGGTGGTGGAAAGC
GGTGGCCAGTTTCAGGTTGTCATAGGTAACCATGTGGCCGATGTCTTCCTGGCGGTTAACAGCGTGGCAGGCCTTGGCGA
AAAAGCGCAACAGGCACCGGAAAATGATGATAAAGGTAATCTGTTAAACCGCTTTGTTTATGTTATTTCAGGTATTTTTA
CGCCTCTGATCGGTTTGATGGCGGCAACCGGGATCCTGAAAGGTATGTTGGCTCTGGCACTCACTTTTCAGTGGACGACC
GAACAAAGTGGTACTTATTTAATTTTATTTAGCGCCAGTGATGCCTTGTTTTGGTTCTTCCCGATAATCCTGGGCTACAC
CGCAGGGAAACGCTTCAGCGGCAATCCATTTACTGCCATGGTGATTGGCGGAGCGTTAGTGCATCCATTAATTCTGACTG
CCTTCGAGAACGGGCAAAAAGTGGATGCGCTGGGCCTGGATTTCCTGGGTATTCCGGTCACATTGTTGAATTACTCGTCA
TCGGTTATTCCCATTATTTTTTCTGCCTGGTTGTGCAGCATTCTGGAACGCCGACTTAATGCGTGGTTACCTTCGGCAAT
CAAAAATTTCTTCACACCCTTGCTATGTCTGATGGTCATCACGCCCATCACATTTCTGCTGGTGGGGCCGCTATCAACCT
GGATAAGTGAACTGATTGCTGCCGGTTATCTCTGGCTTTATCAGGCGGTTCCTGCATTTGCAGGCGCGGTAATGGGCGGC
TTCTGGCAAATCTTTGTGATGTTCGGTCTGCATTGGGGTTTGATACCTTTAATTATCAATAACTTCACCGTGCTGGGCTA
CGACACCATGATCCCGCTGTTAAGGCCCGCCATTATGGCGCAAGTCGGGGCGGCGCTCGGCGTCTTCCTCTGCGAACGCG
ATGCACAGAAAAAAGTGGTGGCGGGATCAGCGGCGTTGACAGGTCTGTTTGGTATCACCGAACCAGCGGTATATGGCGTC
AATCTGCCGCGTAAGTACCCCTTCGTTATCGCCTGCATAAGTGGGGCATTGGGGGCCACCATCATTGGCTACGCGCAAAC
GAAAGTTTACTCCTTTGGTTTGCCAGGTATTTTCACCTTCATGCAAACCATCCCGTCAACGGGGATTGATTTCACCGTAT
GGGCCAGCGTTATTGGCGGTGTCATTGCCATCGGTTGCGCATTTGTCGGTACGGTGATGTTTCATTTCATCACCGCTAAG
AGTCAGTCAGCGCAAGTTGCCCAGCAAGAGAAAACACCAGAGGTTATTACACCTGAGCAGGGCGGTATCTGTTCACCGAT
GACGGGAGAGATTGTGCCGCTCATTCACGTCGCTGATACCACGTTTGCCAGCGGCCTGTTGGGTAAAGGTATTGCCATTC
TGCCCTCTGTTGGTGAAGTGCGTTCTCCGGTGGCGGGTCGAATTGCTTCGTTGTTCGCCACATTACATGCCATCGGCATT
GAGTCAGATGATGGCGTGGAGATCCTGATTCATGTCGGTATCGACACCGTAAAACTGGACGGCAAATTCTTTTCCGCTCA
CGTCAACGTGGGTGACAAGGTCAATACAGGCGATCGGCTGATTTCTTTTGATATCCCTGCTATTCGCGAGGCCGGATTTG
ATCTGACGACGCCGGTATTAATCAGTAATAGCGATGATTTTACGGACGTATTACCCCACGGCACGGCGCAGATAAACGCT
GGTGAGCCGCTGTTATCCATCATTCGCTAA

Upstream 100 bases:

>100_bases
TTTTTAGCCATAAATATAGAGCGCGTGCGCAAAGAACACTGAAATATTATTACTGAATAAAGGATTGTTACCGCACTAAG
CGGGCAAAACCTGAAAAAAA

Downstream 100 bases:

>100_bases
CGATAAAAGGAGTTAATTATGAAAGCATTTCCAGAAACATTTCTTTGGGGTGGTGCAACAGCTGCCAATCAGATGGAAGG
CGCCTGGCAGGAAGATGGCA

Product: PTS system beta-glucoside-specific transporter subunits IIABC

Products: NA

Alternate protein names: EIIBCA-Bgl; EII-Bgl; Beta-glucoside-specific phosphotransferase enzyme IIB component; PTS system beta-glucoside-specific EIIB component; Beta-glucoside permease IIC component; PTS system beta-glucoside-specific EIIC component; Beta-glucoside-specific phosphotransferase enzyme IIA component; PTS system beta-glucoside-specific EIIA component [H]

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MLDSRQAVFFRFFFGVLPQSGRGQVMTELARTIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLKKTPGIIMVVES
GGQFQVVIGNHVADVFLAVNSVAGLGEKAQQAPENDDKGNLLNRFVYVISGIFTPLIGLMAATGILKGMLALALTFQWTT
EQSGTYLILFSASDALFWFFPIILGYTAGKRFSGNPFTAMVIGGALVHPLILTAFENGQKVDALGLDFLGIPVTLLNYSS
SVIPIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPITFLLVGPLSTWISELIAAGYLWLYQAVPAFAGAVMGG
FWQIFVMFGLHWGLIPLIINNFTVLGYDTMIPLLRPAIMAQVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGV
NLPRKYPFVIACISGALGATIIGYAQTKVYSFGLPGIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMFHFITAK
SQSAQVAQQEKTPEVITPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEVRSPVAGRIASLFATLHAIGI
ESDDGVEILIHVGIDTVKLDGKFFSAHVNVGDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQINA
GEPLLSIIR

Sequences:

>Translated_649_residues
MLDSRQAVFFRFFFGVLPQSGRGQVMTELARTIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLKKTPGIIMVVES
GGQFQVVIGNHVADVFLAVNSVAGLGEKAQQAPENDDKGNLLNRFVYVISGIFTPLIGLMAATGILKGMLALALTFQWTT
EQSGTYLILFSASDALFWFFPIILGYTAGKRFSGNPFTAMVIGGALVHPLILTAFENGQKVDALGLDFLGIPVTLLNYSS
SVIPIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPITFLLVGPLSTWISELIAAGYLWLYQAVPAFAGAVMGG
FWQIFVMFGLHWGLIPLIINNFTVLGYDTMIPLLRPAIMAQVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGV
NLPRKYPFVIACISGALGATIIGYAQTKVYSFGLPGIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMFHFITAK
SQSAQVAQQEKTPEVITPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEVRSPVAGRIASLFATLHAIGI
ESDDGVEILIHVGIDTVKLDGKFFSAHVNVGDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQINA
GEPLLSIIR
>Mature_649_residues
MLDSRQAVFFRFFFGVLPQSGRGQVMTELARTIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLKKTPGIIMVVES
GGQFQVVIGNHVADVFLAVNSVAGLGEKAQQAPENDDKGNLLNRFVYVISGIFTPLIGLMAATGILKGMLALALTFQWTT
EQSGTYLILFSASDALFWFFPIILGYTAGKRFSGNPFTAMVIGGALVHPLILTAFENGQKVDALGLDFLGIPVTLLNYSS
SVIPIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPITFLLVGPLSTWISELIAAGYLWLYQAVPAFAGAVMGG
FWQIFVMFGLHWGLIPLIINNFTVLGYDTMIPLLRPAIMAQVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGV
NLPRKYPFVIACISGALGATIIGYAQTKVYSFGLPGIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMFHFITAK
SQSAQVAQQEKTPEVITPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEVRSPVAGRIASLFATLHAIGI
ESDDGVEILIHVGIDTVKLDGKFFSAHVNVGDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQINA
GEPLLSIIR

Specific function: Acts as both a kinase and a phosphatase on BglG [H]

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=625, Percent_Identity=97.28, Blast_Score=1215, Evalue=0.0,
Organism=Escherichia coli, GI48994906, Length=489, Percent_Identity=31.0838445807771, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1788769, Length=423, Percent_Identity=30.2600472813239, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI2367362, Length=428, Percent_Identity=25.4672897196262, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI1788757, Length=146, Percent_Identity=41.0958904109589, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1786894, Length=148, Percent_Identity=38.5135135135135, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011297 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 69290; Mature: 69290

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSRQAVFFRFFFGVLPQSGRGQVMTELARTIVAGVGGADNIVSLMHCATRLRFKLKDE
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCC
SKAQAEVLKKTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGLGEKAQQAPENDDKGN
CHHHHHHHHCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCHHHHCCCCCCCCHH
LLNRFVYVISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFWFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCCHHHHHH
PIILGYTAGKRFSGNPFTAMVIGGALVHPLILTAFENGQKVDALGLDFLGIPVTLLNYSS
HHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEECCCCHHCCCHHEECCCC
SVIPIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPITFLLVGPLSTWISELIA
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGYLWLYQAVPAFAGAVMGGFWQIFVMFGLHWGLIPLIINNFTVLGYDTMIPLLRPAIMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHH
QVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGVNLPRKYPFVIACISGALGAT
HHHHHHHHHHHCCCHHHHHHCCHHHHHHHHCCCCCCEECCCCCCCCCEEEEEHHHHHHHH
IIGYAQTKVYSFGLPGIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMFHFITAK
HHHHHHHEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SQSAQVAQQEKTPEVITPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEV
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCEEECCCCHHH
RSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFSAHVNVGDKVNTGDRL
HCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEECCEEEEEEECCCCCCCCCCEE
ISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQINAGEPLLSIIR
EEECCCHHHHCCCCCCCCEEEECCCCHHHHCCCCCEEECCCCHHHHHCC
>Mature Secondary Structure
MLDSRQAVFFRFFFGVLPQSGRGQVMTELARTIVAGVGGADNIVSLMHCATRLRFKLKDE
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCC
SKAQAEVLKKTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGLGEKAQQAPENDDKGN
CHHHHHHHHCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCHHHHCCCCCCCCHH
LLNRFVYVISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFWFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCCHHHHHH
PIILGYTAGKRFSGNPFTAMVIGGALVHPLILTAFENGQKVDALGLDFLGIPVTLLNYSS
HHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEECCCCHHCCCHHEECCCC
SVIPIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPITFLLVGPLSTWISELIA
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGYLWLYQAVPAFAGAVMGGFWQIFVMFGLHWGLIPLIINNFTVLGYDTMIPLLRPAIMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHH
QVGAALGVFLCERDAQKKVVAGSAALTGLFGITEPAVYGVNLPRKYPFVIACISGALGAT
HHHHHHHHHHHCCCHHHHHHCCHHHHHHHHCCCCCCEECCCCCCCCCEEEEEHHHHHHHH
IIGYAQTKVYSFGLPGIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMFHFITAK
HHHHHHHEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SQSAQVAQQEKTPEVITPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEV
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCEEECCCCHHH
RSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFSAHVNVGDKVNTGDRL
HCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEECCEEEEEEECCCCCCCCCCEE
ISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQINAGEPLLSIIR
EEECCCHHHHCCCCCCCCEEEECCCCHHHHCCCCCEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3309161; 3034860; 7686882; 9278503 [H]