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The map label for this gene is bglB [H]

Identifier: 218692009

GI number: 218692009

Start: 4339207

End: 4340601

Strand: Reverse

Name: bglB [H]

Synonym: ECED1_4411

Alternate gene names: 218692009

Gene position: 4340601-4339207 (Counterclockwise)

Preceding gene: 218692010

Following gene: 218692008

Centisome position: 83.32

GC content: 47.67

Gene sequence:

>1395_bases
ATGAAAGCATTTCCAGAAACATTTCTTTGGGGTGGTGCAACAGCTGCCAATCAGATGGAAGGCGCCTGGCAGGAAGATGG
CAAAGGGATCACGACCTCAGATTTACAGCCTCATGGCGTAATGGGAAAAATGGAACCGCGCATCCTGGGGAAAGAGAATA
TCAAAGATGTCGCCATCGATTTTTATCACCGTTACCCGGAAGATATCGCGTTATTTGCCGAGATGGGCTTCACCTGTCTG
CGTATTTCCATTGCCTGGGCGCGAATTTTTCCTCAGGGCGATGAAGCCGAACCGAATGAAGCGGGGTTAGCATTTTACGA
GCGGCTGTTTGATGAAATGGCGCAGGCGGGGATCAAGCCGCTGGTAACGTTATCCCATTACGAAATGCCATATGGGCTGG
TGAAAAACTACGGCGGTTGGGCTAATCGGGCGGTCATCGATCACTTCGAGCATTACGCACGCACGGTCTTTACCCGCTAC
CAACATAAAGTTGCGTTATGGCTGACATTTAATGAAATCAACATGTCATTACACGCGCCATTCACGGGCGTGGGGCTGGC
AGAAGAGAGTGGCGAGGCGGAAGTTTATCAGGCGATCCATCATCAACTGGTTGCCAGTGCGCGGGCAGTTAAAGCCTGTC
ATAGCCTGATCCCCGAAGCGAAAATTGGCAATATGCTTCTCGGTGGGCTGGTTTACCCCCTCACCTGCCAGCCACAGGAT
ATGTTGCAGGCCATGGAAGAGAACCGGCGCTGGATGTTCTTTGGTGATGTTCAGGCGCGTGGTCAGTATCCCGGCTATAT
GCAGCGTTTCTTCCGCGACCACAATATCACCATTGAGATGACTGAAAGTGACGCAGAAGATTTAAAACATACCGTAGATT
TCATCTCTTTTAGTTATTACATGACCGGTTGTGTTTCCCACGACGAAAGCATTAATAAAAATGCGCAGGGCAACATACTG
AATATGATCCCAAATCCGCATCTGAAAATTTCAGAGTGGGGGTGGCAAATTGATCCGGTTGGATTACGGATTCTGTTAAA
TACGCTTTGGGATCGTTATCAAAAACCGTTATTTATTGTCGAGAACGGATTAGGCGCAAAAGACAGCGTTGAAGTGGATG
GTTCGATACAGGACGATTATCGAATTGCCTATTTAAACGATCACCTGGTACAGGTAAATGAAGCGATTGCCGATGGTGTG
GATATTATGGGGTACACCAGTTGGGGGCCAATTGATTTAGTCAGTGCATCTCATTCACAAATGTCTAAGCGCTACGGCTT
TATTTATGTGGATCGTGATGATAATGGTGAAGGAAGCCTCACAAGAACGCGCAAGAAAAGCTTCGGATGGTATGCAGAAG
TGATCAAAACTCGGGGGCTATCATTAAAAAAATAA

Upstream 100 bases:

>100_bases
TAGCGATGATTTTACGGACGTATTACCCCACGGCACGGCGCAGATAAACGCTGGTGAGCCGCTGTTATCCATCATTCGCT
AACGATAAAAGGAGTTAATT

Downstream 100 bases:

>100_bases
CCAATAAAGCACCTTAATTATCGTCGCATTCAGAACAGTCTGGATGCGATTCATTAATTCTTTCTTTGCACCATAAAGGG
ATATTATGTTTAGACGAAAT

Product: cryptic phospho-beta-glucosidase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MKAFPETFLWGGATAANQMEGAWQEDGKGITTSDLQPHGVMGKMEPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCL
RISIAWARIFPQGDEAEPNEAGLAFYERLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRY
QHKVALWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLIPEAKIGNMLLGGLVYPLTCQPQD
MLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNITIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNIL
NMIPNPHLKISEWGWQIDPVGLRILLNTLWDRYQKPLFIVENGLGAKDSVEVDGSIQDDYRIAYLNDHLVQVNEAIADGV
DIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGWYAEVIKTRGLSLKK

Sequences:

>Translated_464_residues
MKAFPETFLWGGATAANQMEGAWQEDGKGITTSDLQPHGVMGKMEPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCL
RISIAWARIFPQGDEAEPNEAGLAFYERLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRY
QHKVALWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLIPEAKIGNMLLGGLVYPLTCQPQD
MLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNITIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNIL
NMIPNPHLKISEWGWQIDPVGLRILLNTLWDRYQKPLFIVENGLGAKDSVEVDGSIQDDYRIAYLNDHLVQVNEAIADGV
DIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGWYAEVIKTRGLSLKK
>Mature_464_residues
MKAFPETFLWGGATAANQMEGAWQEDGKGITTSDLQPHGVMGKMEPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCL
RISIAWARIFPQGDEAEPNEAGLAFYERLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRY
QHKVALWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLIPEAKIGNMLLGGLVYPLTCQPQD
MLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNITIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNIL
NMIPNPHLKISEWGWQIDPVGLRILLNTLWDRYQKPLFIVENGLGAKDSVEVDGSIQDDYRIAYLNDHLVQVNEAIADGV
DIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGWYAEVIKTRGLSLKK

Specific function: Can hydrolyze salicin and arbutin [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=482, Percent_Identity=29.253112033195, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI110681710, Length=496, Percent_Identity=30.4435483870968, Blast_Score=186, Evalue=6e-47,
Organism=Homo sapiens, GI13273313, Length=483, Percent_Identity=29.1925465838509, Blast_Score=181, Evalue=9e-46,
Organism=Homo sapiens, GI24497614, Length=483, Percent_Identity=29.6066252587992, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI28376633, Length=478, Percent_Identity=26.7782426778243, Blast_Score=145, Evalue=8e-35,
Organism=Escherichia coli, GI2367270, Length=464, Percent_Identity=98.2758620689655, Blast_Score=963, Evalue=0.0,
Organism=Escherichia coli, GI1789070, Length=474, Percent_Identity=54.4303797468354, Blast_Score=542, Evalue=1e-155,
Organism=Escherichia coli, GI2367174, Length=474, Percent_Identity=50.6329113924051, Blast_Score=468, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17552856, Length=478, Percent_Identity=28.8702928870293, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17539390, Length=478, Percent_Identity=28.0334728033473, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21356577, Length=493, Percent_Identity=27.3833671399594, Blast_Score=149, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 52638; Mature: 52638

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFPETFLWGGATAANQMEGAWQEDGKGITTSDLQPHGVMGKMEPRILGKENIKDVAID
CCCCCCHHCCCCCCHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
FYHRYPEDIALFAEMGFTCLRISIAWARIFPQGDEAEPNEAGLAFYERLFDEMAQAGIKP
HHHHCCHHHHHHHHHCCEEEHHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCE
LVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRYQHKVALWLTFNEINMSLHAP
EEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECEEEECC
FTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLIPEAKIGNMLLGGLVYPLTCQPQD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHCCEEEEEECCHHH
MLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNITIEMTESDAEDLKHTVDFISFSYY
HHHHHHCCCCEEEEECEECCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHH
MTGCVSHDESINKNAQGNILNMIPNPHLKISEWGWQIDPVGLRILLNTLWDRYQKPLFIV
HHHHCCCCCCCCCCCCCCEEEECCCCCEEEECCCCEECCHHHHHHHHHHHHHHCCCEEEE
ENGLGAKDSVEVDGSIQDDYRIAYLNDHLVQVNEAIADGVDIMGYTSWGPIDLVSASHSQ
ECCCCCCCCEEECCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEECCCCCEEEECCCHHH
MSKRYGFIYVDRDDNGEGSLTRTRKKSFGWYAEVIKTRGLSLKK
HHHHCCEEEEECCCCCCCCEEHHHHHHCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKAFPETFLWGGATAANQMEGAWQEDGKGITTSDLQPHGVMGKMEPRILGKENIKDVAID
CCCCCCHHCCCCCCHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
FYHRYPEDIALFAEMGFTCLRISIAWARIFPQGDEAEPNEAGLAFYERLFDEMAQAGIKP
HHHHCCHHHHHHHHHCCEEEHHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCE
LVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRYQHKVALWLTFNEINMSLHAP
EEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECEEEECC
FTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLIPEAKIGNMLLGGLVYPLTCQPQD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHCCEEEEEECCHHH
MLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNITIEMTESDAEDLKHTVDFISFSYY
HHHHHHCCCCEEEEECEECCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHH
MTGCVSHDESINKNAQGNILNMIPNPHLKISEWGWQIDPVGLRILLNTLWDRYQKPLFIV
HHHHCCCCCCCCCCCCCCEEEECCCCCEEEECCCCEECCHHHHHHHHHHHHHHCCCEEEE
ENGLGAKDSVEVDGSIQDDYRIAYLNDHLVQVNEAIADGVDIMGYTSWGPIDLVSASHSQ
ECCCCCCCCEEECCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEECCCCCEEEECCCHHH
MSKRYGFIYVDRDDNGEGSLTRTRKKSFGWYAEVIKTRGLSLKK
HHHHCCEEEEECCCCCCCCEEHHHHHHCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3034860; 7686882; 9278503; 3309161 [H]