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The map label for this gene is yeiL [H]

Identifier: 218690313

GI number: 218690313

Start: 2537896

End: 2538555

Strand: Direct

Name: yeiL [H]

Synonym: ECED1_2611

Alternate gene names: 218690313

Gene position: 2537896-2538555 (Clockwise)

Preceding gene: 218690311

Following gene: 218690321

Centisome position: 48.72

GC content: 44.24

Gene sequence:

>660_bases
ATGAGTGAATCTGCGTTTAAGGATTGCTTTTCAACGGATGTTTCAGCCGATACGCGGCTGTTTCATTTTTTAGCGCGTGA
CTACATTGTGCAGGAAGGGCAACAGCCGTCCTGGCTGTTTTACCTGACGCGAGGCCGCGCCAGGCTTTACGTCACGCTTG
CTAATGGTCGCGTGTCGCTAATCGATTTCTTTGCCGCGCCCTGTTTTATTGGCGAGATTGAGTTAATCGACAAAGACCAT
GAACCGCGTGCAGTGCAGGCTATTGAAGAGTGTTGGTGCCTTGCGCTCCCTATGAAGCATTACCGCCCGTTGTTATTAAA
CGACACGCTATTTTTACGAAAACTCTGCGTCACCTTAAGTCATAAAAATTATCGTAATATTGTTTCTTTAACTCAGAATC
AATCATTTCCGTTAGTGAATCGCCTGGCAGCTTTTATATTACTCTCGCAGGAAGGTGATCTTTATCACGAAAAGCATACG
CAAGCGGCAGAGTATTTAGGCGTTTCTTATCGACATCTTTTATATGTTCTTGCGCAATTCATTAATGACGGTTTATTAAT
TAAAAGCAAGAAAGGGTATCTCATTAAAAACAGAAAGCAGTTGTCAGGACTGGCGCTGGAGATGGACCCGGAGAATAAAT
TCTCCGGGATGATGCAGTAA

Upstream 100 bases:

>100_bases
TTGAATCTTAACAACAGCGTACGTATGCTAAATATGAGAAATCTCATAGCGGATAAACATCGTGAAAGAAATCCACAATA
ATGATCTTAAGCAGCAATTG

Downstream 100 bases:

>100_bases
AAATTATTGGCAATAGTGCGATTGCCGGATGCAACGCTTAATAAGGCGTACATCCGGCAATGAAACTCAAGCTAAACCAA
TAAAGAACCCGGCAATGGTC

Product: DNA-binding transcriptional activator YeiL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYVTLANGRVSLIDFFAAPCFIGEIELIDKDH
EPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHT
QAAEYLGVSYRHLLYVLAQFINDGLLIKSKKGYLIKNRKQLSGLALEMDPENKFSGMMQ

Sequences:

>Translated_219_residues
MSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYVTLANGRVSLIDFFAAPCFIGEIELIDKDH
EPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHT
QAAEYLGVSYRHLLYVLAQFINDGLLIKSKKGYLIKNRKQLSGLALEMDPENKFSGMMQ
>Mature_218_residues
SESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYVTLANGRVSLIDFFAAPCFIGEIELIDKDHE
PRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHTQ
AAEYLGVSYRHLLYVLAQFINDGLLIKSKKGYLIKNRKQLSGLALEMDPENKFSGMMQ

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=219, Percent_Identity=98.6301369863014, Blast_Score=450, Evalue=1e-128,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 25274; Mature: 25142

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYVTLANGRVSL
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEECCCCHH
IDFFAAPCFIGEIELIDKDHEPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLS
HHHHHCCHHCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCEEECCHHHHHHHHHHHC
HKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQF
CCCHHHHHHHHCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
INDGLLIKSKKGYLIKNRKQLSGLALEMDPENKFSGMMQ
HCCCEEEECCCCCEEECCHHHCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYVTLANGRVSL
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEECCCCHH
IDFFAAPCFIGEIELIDKDHEPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLS
HHHHHCCHHCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCEEECCHHHHHHHHHHHC
HKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQF
CCCHHHHHHHHCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
INDGLLIKSKKGYLIKNRKQLSGLALEMDPENKFSGMMQ
HCCCEEEECCCCCEEECCHHHCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]