| Definition | Escherichia coli ED1a chromosome, complete genome. |
|---|---|
| Accession | NC_011745 |
| Length | 5,209,548 |
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The map label for this gene is aroH [H]
Identifier: 218689649
GI number: 218689649
Start: 1866532
End: 1867578
Strand: Direct
Name: aroH [H]
Synonym: ECED1_1906
Alternate gene names: 218689649
Gene position: 1866532-1867578 (Clockwise)
Preceding gene: 218689648
Following gene: 218689650
Centisome position: 35.83
GC content: 53.3
Gene sequence:
>1047_bases ATGAACAGAACTGACGAACTCCGTACTGCGCGTATTGAGAGCCTGGTAACGCCCGCCGAACTCGCGCTACGGTATCCCGT AACGCCTGGCGTCGCCACCCATGTCACCGACTCCCGCCGTAGAATTGAAAAAATACTGAATGGTGAAGATAAGCGACTGT TGGTCATTATTGGCCCCTGCTCGATCCACGATCTCACCGCTGCGATGGAGTACGCCACCCGTCTGCAGTCGCTACGCAAC CAGTACCAGCCACGGCTGGAAATCGTAATGCGCACCTATTTTGAAAAACCACGAACGGTTGTCGGCTGGAAAGGACTCAT CTCCGATCCAGATTTAAACGGTAGCTATCGGGTAAATCACGGTCTGGAGCTGGCGCGCAAATTACTTTTACAGGTAAATG AGCTGGGCGTCCCTACCGCGACTGAGTTCCTCGATATGGTGACCGGTCAGTTTATTGCTGATTTAATCAGTTGGGGCGCG ATTGGCGCACGTACTACCGAAAGTCAGATCCACCGCGAAATGGCTTCGGCACTCTCCTGTCCGGTGGGTTTTAAAAATGG TACCGATGGCAACACGCGGATTGCCGTGGATGCTATCCGCGCAGCCCGCGCCAGCCATATGTTCCTCTCACCAGACAAAA ACGGTCAGATGACCATCTATCAGACCAGCGGCAACCCGTATGGCCACATTATTATGCGTGGCGGCAAAAAACCGAATTAT CATGCCGATGATATCGCCGCAGCCTGCGATACGCTGCACGAGTTTGATTTACCTGAACATCTGGTGGTGGATTTCAGCCA CGGTAACTGCCAGAAGCAGCACCGTCGCCAGTTAGAAGTTTGTGAGGATATTTGTCAGCAAATCCGCAATGGCTCTACGG CGATTGCTGGAATTATGGCGGAAAGTTTCCTGCGCGAAGGAACGCAAAAAATCGTCGGCGGTCAGCCGCTCACTTACGGT CAATCCATTACCGACCCGTGTCTGGGCTGGGAAGATACCGAACGCCTGGTCGAAAAACTCGCCTCTGCGGTAGATACTCG CTTCTGA
Upstream 100 bases:
>100_bases GACACACCTCGCACTTGAAATCAGCTGCGATTGGTTTATCGTGATGCGCATCACTTCCCGGTAGTCCTGCCGTAGAAGCA ACAAATTTCTGAGACTTGTA
Downstream 100 bases:
>100_bases ATGCGTGCCCATTCCTGACGGGATGGGCATTTCTGCGCAACTTGTTGTCTTCTCAACAAATTACTACTTGCTCTGGCCCG CCATAATATTGATAATAAGA
Product: phospho-2-dehydro-3-deoxyheptonate aldolase
Products: NA
Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]
Number of amino acids: Translated: 348; Mature: 348
Protein sequence:
>348_residues MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRN QYQPRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYG QSITDPCLGWEDTERLVEKLASAVDTRF
Sequences:
>Translated_348_residues MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRN QYQPRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYG QSITDPCLGWEDTERLVEKLASAVDTRF >Mature_348_residues MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRN QYQPRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYG QSITDPCLGWEDTERLVEKLASAVDTRF
Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]
COG id: COG0722
COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-I DAHP synthase family [H]
Homologues:
Organism=Escherichia coli, GI1787996, Length=348, Percent_Identity=99.4252873563218, Blast_Score=722, Evalue=0.0, Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=57.1014492753623, Blast_Score=423, Evalue=1e-119, Organism=Escherichia coli, GI1788953, Length=329, Percent_Identity=49.5440729483283, Blast_Score=335, Evalue=3e-93, Organism=Saccharomyces cerevisiae, GI6319726, Length=349, Percent_Identity=48.9971346704871, Blast_Score=337, Evalue=2e-93, Organism=Saccharomyces cerevisiae, GI6320240, Length=353, Percent_Identity=42.7762039660057, Blast_Score=293, Evalue=2e-80,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013785 - InterPro: IPR006218 - InterPro: IPR006219 [H]
Pfam domain/function: PF00793 DAHP_synth_1 [H]
EC number: =2.5.1.54 [H]
Molecular weight: Translated: 38716; Mature: 38716
Theoretical pI: Translated: 6.90; Mature: 6.90
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 4.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEKILNGEDKRLLVIIGPC CCCCHHHHHHHHHHHCCHHHHHEECCCCCCCHHHCCHHHHHHHHHHCCCCCEEEEEECCC SIHDLTAAMEYATRLQSLRNQYQPRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNH CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECH GLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSC HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC PVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY CCCCCCCCCCCCEEHHHHHHHHHHCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMA CHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH ESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTERLVEKLASAVDTRF HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEKILNGEDKRLLVIIGPC CCCCHHHHHHHHHHHCCHHHHHEECCCCCCCHHHCCHHHHHHHHHHCCCCCEEEEEECCC SIHDLTAAMEYATRLQSLRNQYQPRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNH CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECH GLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSC HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC PVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY CCCCCCCCCCCCEEHHHHHHHHHHCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMA CHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH ESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTERLVEKLASAVDTRF HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]