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The map label for this gene is ycbL [H]

Identifier: 218688770

GI number: 218688770

Start: 988186

End: 988833

Strand: Direct

Name: ycbL [H]

Synonym: ECED1_0957

Alternate gene names: 218688770

Gene position: 988186-988833 (Clockwise)

Preceding gene: 218688769

Following gene: 218688775

Centisome position: 18.97

GC content: 51.85

Gene sequence:

>648_bases
ATGAACTATCGTATTATTCCGGTCACCGCATTCTCCCAGAACTGTTCATTGATCTGGTGTGAACAAACCCGTCTGGCCGC
ACTGGTCGATCCTGGCGGCGATGCGGAAAAAATCAAACAGGAAGTTGATGCCAGCGGCCTGACACTGATGCAGATCCTGC
TGACTCATGGTCATCTGGACCACGTTGGCGCAGCGGCGGAACTGGCGCAACATTACGGCGTGCCGGTTTTTGGCCCGGAA
AAAGAAGATGAGTTCTGGCTGCAAGGCTTGCCTGCGCAAAGTCGTATGTTTGGTCTGGAAGAGTGCCAGCCGCTGACGCC
AGATCGTTGGCTGAACGAAGGCGATACCATCAGCATAGGGAATGTGACTTTACAGGTGTTACATTGCCCTGGGCATACGC
CGGGTCATGTCGTGTTTTTTGATGATCGGGCAAAGCTGCTGATTTCTGGCGACGTTATTTTCAAAGGTGGAGTAGGGCGC
AGTGACTTCCCGCGTGGCGATCATAATCAACTGATTTCTTCAATCAAAGATAAATTGCTGCCACTGGGGGATGACGTGAC
ATTTATTCCGGGTCACGGACCATTATCCACACTTGGTTATGAGCGCCTGCATAATCCCTTCCTGCAAGACGAAATGCCCG
TCTGGTAA

Upstream 100 bases:

>100_bases
GCGCAGGTGGTGTAGGATATTACCCACGTAGTAACTTTGTGCATATTGATACCGGGCCAGCACGGCACTGGTAGTAATCG
CTTAACGAAACAGGGGCAGT

Downstream 100 bases:

>100_bases
AGGTGCATAAAAAAGCCCGCTTTCAAGCGGGCTTCATTGTTTTTAACGCTTACAGCACTGCCACAATCGCTTCGCACAGC
GGTGCCATGTTATCTGGTGT

Product: putative metal-binding hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPE
KEDEFWLQGLPAQSRMFGLEECQPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGR
SDFPRGDHNQLISSIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW

Sequences:

>Translated_215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPE
KEDEFWLQGLPAQSRMFGLEECQPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGR
SDFPRGDHNQLISSIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW
>Mature_215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPE
KEDEFWLQGLPAQSRMFGLEECQPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGR
SDFPRGDHNQLISSIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI21703352, Length=196, Percent_Identity=32.6530612244898, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI116642887, Length=196, Percent_Identity=32.6530612244898, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI41327741, Length=194, Percent_Identity=29.3814432989691, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787158, Length=215, Percent_Identity=99.0697674418605, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23728; Mature: 23728

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLD
CCEEEEEEEEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCHH
HVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEECQPLTPDRWLNEGDTISIG
HHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHCCHHHCCCCCCHHHCCCCCEEEEC
NVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGRSDFPRGDHNQLISSIKDKLL
CEEEEEEECCCCCCCEEEEECCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW
CCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLD
CCEEEEEEEEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCHH
HVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEECQPLTPDRWLNEGDTISIG
HHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHCCHHHCCCCCCHHHCCCCCEEEEC
NVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGRSDFPRGDHNQLISSIKDKLL
CEEEEEEECCCCCCCEEEEECCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW
CCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]