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The map label for this gene is bolA

Identifier: 218688298

GI number: 218688298

Start: 475194

End: 475511

Strand: Direct

Name: bolA

Synonym: ECED1_0458

Alternate gene names: 218688298

Gene position: 475194-475511 (Clockwise)

Preceding gene: 218688289

Following gene: 218688299

Centisome position: 9.12

GC content: 48.43

Gene sequence:

>318_bases
ATGATGATACGTGAGCGGATAGAAGAAAAATTAAGGGCGGCGTTCCAACCCGTATTCCTCGAAGTAGTGGATGAAAGCTA
TCGTCACAATGTCCCAGCCGGCTCTGAAAGCCATTTTAAAGTTGTGCTGGTCAGCGATCGTTTTACGGGTGAACGTTTTC
TGAATCGTCATCGAATGATTTACAGTACTTTAGCGGAGGAACTCTCTACTACCGTTCATGCGCTGGCTCTGCATACTTAC
ACTATTAAGGAGTGGGAAGGGTTGCAGGACACCGTCTTTGCCTCTCCTCCCTGTCGTGGAGCAGGAAGCATCGCGTAA

Upstream 100 bases:

>100_bases
GAAACCTAAATATTTGTTGTTAAGCTGCAATGGAAACGGTAAAAGCGGCTAGTATTTAAAGGGATGGATGACATCTCAGC
GTTGTCGGAGGAGATATTTC

Downstream 100 bases:

>100_bases
AAACGCATTTGCAACTGTCGGCGCTTTTCCAGTATGTTGCTAAAGATTTTATGAAAAACGGCCTGCGGGCCGTTTTGTTT
TGTCTGGATTTTGCGCTTTT

Product: transcriptional regulator BolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTY
TIKEWEGLQDTVFASPPCRGAGSIA

Sequences:

>Translated_105_residues
MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTY
TIKEWEGLQDTVFASPPCRGAGSIA
>Mature_105_residues
MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTY
TIKEWEGLQDTVFASPPCRGAGSIA

Specific function: Plays an important role in general stress response (heat shock, acidic stress, oxidative stress, carbon-starvation stress and osmotic shock). Involved in morphogenetic pathway. Has a role in the induction of the expression of dacA (PBP5), dacC (PBP6) and

COG id: COG0271

COG function: function code T; Stress-induced morphogen (activity unknown)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bolA/yrbA family

Homologues:

Organism=Homo sapiens, GI7705638, Length=95, Percent_Identity=46.3157894736842, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081740, Length=105, Percent_Identity=100, Blast_Score=218, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17541430, Length=95, Percent_Identity=50.5263157894737, Blast_Score=99, Evalue=3e-22,
Organism=Drosophila melanogaster, GI221459039, Length=103, Percent_Identity=38.8349514563107, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BOLA_ECOL6 (P0ABE3)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_752482.2
- ProteinModelPortal:   P0ABE3
- SMR:   P0ABE3
- MINT:   MINT-1238054
- EnsemblBacteria:   EBESCT00000042613
- GeneID:   1038029
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c0548
- GeneTree:   EBGT00050000009479
- HOGENOM:   HBG739421
- OMA:   LHALSMH
- ProtClustDB:   PRK11628
- GO:   GO:0006350
- InterPro:   IPR002634
- Gene3D:   G3DSA:3.30.300.90
- PANTHER:   PTHR12735
- PIRSF:   PIRSF003113

Pfam domain/function: PF01722 BolA; SSF82657 BolA

EC number: NA

Molecular weight: Translated: 11994; Mature: 11994

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHH
YSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAGSIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHH
YSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAGSIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157