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The map label for this gene is fimC [H]

Identifier: 218550692

GI number: 218550692

Start: 3467647

End: 3468399

Strand: Reverse

Name: fimC [H]

Synonym: EFER_3403

Alternate gene names: 218550692

Gene position: 3468399-3467647 (Counterclockwise)

Preceding gene: 218550693

Following gene: 218550691

Centisome position: 75.59

GC content: 40.64

Gene sequence:

>753_bases
ATGAGATGGATTTCAAAAAATAAATGTTTTACGAATAGAAACATTAATTCTTTGCTGAATGCTCAATATGTCATAAGGGT
CGGTGCTCTATTTTTACTGTCTGCCATATCTGTCAACTCTATTGCTGCGGGTGGTTTCGGCCTCGGCTCCACGCGTCTGA
TTTATCCATCTGACAGTCAGCAAATTACATTAAATGTGCAGAATGGTGGGGCTAACACCAGCTATTTAATCCAGTCATGG
GTTGATGACAATCAAAGCAGTAAAAAAAGTCAGGATTTTGTGGTTACGCCTCCTTTATTTATGTTGCCAACGCGAAAAGA
AGCATCATTGAGGATAATGTTTATTGGTAAATCACAGTTACCGACTGATCGCGAAACATTATTCTGGATGAATGTGAAAG
CGATTCCGCCAACGGATGAGAAGAATACCCAGAAAAACACGTTACAACTGGCGTTACAAAACAGAATTAAATTATTTTAC
CGTCCAATAAATTTACCTGTCCAGGCTGGTAAAGCGCGGGATATGCTGCGATTTAAATACGAAGGTAAACAACTGAAAAT
CATTAACCCTTCTCCCTATTATCTGACGGTGACTGGAATCAGGGTGCAAGGGACAAAATTACCTAATACGTTTGTTCCCC
CGAAAAGTGACATCACAGTAACTTCACCGGTGACGTTAGCGGGGGAAATTACGTATCAAACAATTAATGATTACGGTGCT
ACGACGGCCAGGCAAAAGGGAACGATGCAATAA

Upstream 100 bases:

>100_bases
GTTACAGTTATTTGTAGCCTGAAATTAATATTACGTGTTGAATTATAATAAATAGACACGTATCAGTAATTAAAATTAGT
TTCATCTACAAGGATGCAGT

Downstream 100 bases:

>100_bases
ACCTGGAAGATAAAACATTAAAGTAACTCAGGTCAGGGATATGAACCTAAAGCTCAGAAAACTCGAACACGGGATGGCAA
GGCACAAGCAGATGAGGCGG

Product: fimbria chaperone protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MRWISKNKCFTNRNINSLLNAQYVIRVGALFLLSAISVNSIAAGGFGLGSTRLIYPSDSQQITLNVQNGGANTSYLIQSW
VDDNQSSKKSQDFVVTPPLFMLPTRKEASLRIMFIGKSQLPTDRETLFWMNVKAIPPTDEKNTQKNTLQLALQNRIKLFY
RPINLPVQAGKARDMLRFKYEGKQLKIINPSPYYLTVTGIRVQGTKLPNTFVPPKSDITVTSPVTLAGEITYQTINDYGA
TTARQKGTMQ

Sequences:

>Translated_250_residues
MRWISKNKCFTNRNINSLLNAQYVIRVGALFLLSAISVNSIAAGGFGLGSTRLIYPSDSQQITLNVQNGGANTSYLIQSW
VDDNQSSKKSQDFVVTPPLFMLPTRKEASLRIMFIGKSQLPTDRETLFWMNVKAIPPTDEKNTQKNTLQLALQNRIKLFY
RPINLPVQAGKARDMLRFKYEGKQLKIINPSPYYLTVTGIRVQGTKLPNTFVPPKSDITVTSPVTLAGEITYQTINDYGA
TTARQKGTMQ
>Mature_250_residues
MRWISKNKCFTNRNINSLLNAQYVIRVGALFLLSAISVNSIAAGGFGLGSTRLIYPSDSQQITLNVQNGGANTSYLIQSW
VDDNQSSKKSQDFVVTPPLFMLPTRKEASLRIMFIGKSQLPTDRETLFWMNVKAIPPTDEKNTQKNTLQLALQNRIKLFY
RPINLPVQAGKARDMLRFKYEGKQLKIINPSPYYLTVTGIRVQGTKLPNTFVPPKSDITVTSPVTLAGEITYQTINDYGA
TTARQKGTMQ

Specific function: Required for the biogenesis of type 1 fimbriae. Binds and interact with fimH [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1790771, Length=243, Percent_Identity=44.8559670781893, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1786743, Length=208, Percent_Identity=41.3461538461538, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787171, Length=215, Percent_Identity=42.7906976744186, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789532, Length=224, Percent_Identity=35.7142857142857, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1786333, Length=231, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786936, Length=196, Percent_Identity=31.6326530612245, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1788428, Length=222, Percent_Identity=30.6306306306306, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788677, Length=198, Percent_Identity=31.3131313131313, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082203, Length=240, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081806, Length=231, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 27985; Mature: 27985

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWISKNKCFTNRNINSLLNAQYVIRVGALFLLSAISVNSIAAGGFGLGSTRLIYPSDSQ
CCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEECCCCC
QITLNVQNGGANTSYLIQSWVDDNQSSKKSQDFVVTPPLFMLPTRKEASLRIMFIGKSQL
EEEEEEECCCCCHHEEEEECCCCCCCCCCCCCEEECCCEEEEECCCCCEEEEEEEECCCC
PTDRETLFWMNVKAIPPTDEKNTQKNTLQLALQNRIKLFYRPINLPVQAGKARDMLRFKY
CCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCEEEEEEECCCEEECCCCCCEEEEEE
EGKQLKIINPSPYYLTVTGIRVQGTKLPNTFVPPKSDITVTSPVTLAGEITYQTINDYGA
CCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCEEEECCEEEEEEEEEEEECCCCC
TTARQKGTMQ
CCCCCCCCCC
>Mature Secondary Structure
MRWISKNKCFTNRNINSLLNAQYVIRVGALFLLSAISVNSIAAGGFGLGSTRLIYPSDSQ
CCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEECCCCC
QITLNVQNGGANTSYLIQSWVDDNQSSKKSQDFVVTPPLFMLPTRKEASLRIMFIGKSQL
EEEEEEECCCCCHHEEEEECCCCCCCCCCCCCEEECCCEEEEECCCCCEEEEEEEECCCC
PTDRETLFWMNVKAIPPTDEKNTQKNTLQLALQNRIKLFYRPINLPVQAGKARDMLRFKY
CCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCEEEEEEECCCEEECCCCCCEEEEEE
EGKQLKIINPSPYYLTVTGIRVQGTKLPNTFVPPKSDITVTSPVTLAGEITYQTINDYGA
CCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCEEEECCEEEEEEEEEEEECCCCC
TTARQKGTMQ
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]