Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 218550645

GI number: 218550645

Start: 3411737

End: 3412825

Strand: Reverse

Name: aroB [H]

Synonym: EFER_3355

Alternate gene names: 218550645

Gene position: 3412825-3411737 (Counterclockwise)

Preceding gene: 218550646

Following gene: 218550644

Centisome position: 74.37

GC content: 52.53

Gene sequence:

>1089_bases
GTGGAGAGGATTACCGTCACTCTGGGGGAACGTAGTTACCCTATTACCATCGCGGCTGGTTTGTTTAACGAACCGGCTTC
ATTCTTACCGTTGAAGTCAGGTGAGCAGGTTATGTTGGTAACCAACGAAACCCTCGCTCCCCTGTATCTCGATAAAGTTC
GCGGCGTACTTGAACAGGCGGGTGTTATCGTTGACAGCGTTATCCTTCCTGATGGCGAGAAATACAAAAGCCTGACAGTG
CTGGATACGGTCTTTACGGCACTGCTGCAAAAACCTCATGGTCGTGACACCACGCTGGTCGCTCTGGGCGGTGGCGTTAT
TGGTGATCTCACGGGCTTTGCGGCAGCCAGCTACCAACGAGGCGTTCGTTTTATTCAGGTTCCGACCACGCTACTCTCGC
AGGTGGACTCCTCCGTTGGCGGAAAAACCGCTGTAAACCATCCCCTCGGCAAAAATATGATTGGTGCATTTTATCAGCCT
GCATCTGTCGTGGTGGATCTCGACTGTCTGCAAACTCTTCCGGCACGCGAGCTGGCTTCAGGGCTGGCAGAAGTTATTAA
ATACGGCATTATTCTGGATGGTGAGTTCTTTACCTGGCTGGAGGAAAATCTGGACGCCTTATTACGTCTGGATGGCCCGG
CGATGGCGTACTGTATTCGCCGTTGTTGTGAACTGAAAGCCGAAGTTGTTGCTGCAGACGAGCGCGAAACAGGGTTACGT
GCTTTACTGAATCTGGGGCACACCTTTGGTCATGCCATTGAAGCTGAAATGGGTTATGGCAATTGGTTACACGGTGAAGC
TGTTGCTGCGGGTATGGTGATGGCGGCGCGAACCTCAGAACGTTTAGAGCAGTTCAGTTCTGCAGATACGCAGCGTATTA
TTGCGTTGCTCGAGCGTGCGGGGTTGCCGGTAAACGGGCCGCGCGAAATGTCTGCGGAAGCTTATTTGCCGCATATGTTG
CGAGATAAAAAAGTGTTAGCGGGTGAAATGCGCTTAGTTCTCCCGCTGGCATTAGGGAAGAGCGAAGTTCGCGGCGGAGT
GCCGCACGATGTCGTTCTTAGCGCTATTGCTGATTGTCAGCAGGCGTAA

Upstream 100 bases:

>100_bases
AGTCGTCGCAAACCAGATTATCCACATGCTGGAAAGCAACTAATTCTGGTTTCATAAACACTCGTCTGTGAGTACTTGTA
ACTAAGGTGGATGTCGCGTC

Downstream 100 bases:

>100_bases
AAACAAGAAAGGTCAGACCGCCGTATCCGGGGGTCTTTTTGCTTCGGGATTAATGCACGTAGTGAGCATTAACCTTTTAG
TGGGGTGTTAAATGGATGAA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MERITVTLGERSYPITIAAGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVIVDSVILPDGEKYKSLTV
LDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLDCLQTLPARELASGLAEVIKYGIILDGEFFTWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLEQFSSADTQRIIALLERAGLPVNGPREMSAEAYLPHML
RDKKVLAGEMRLVLPLALGKSEVRGGVPHDVVLSAIADCQQA

Sequences:

>Translated_362_residues
MERITVTLGERSYPITIAAGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVIVDSVILPDGEKYKSLTV
LDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLDCLQTLPARELASGLAEVIKYGIILDGEFFTWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLEQFSSADTQRIIALLERAGLPVNGPREMSAEAYLPHML
RDKKVLAGEMRLVLPLALGKSEVRGGVPHDVVLSAIADCQQA
>Mature_362_residues
MERITVTLGERSYPITIAAGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVIVDSVILPDGEKYKSLTV
LDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLDCLQTLPARELASGLAEVIKYGIILDGEFFTWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLEQFSSADTQRIIALLERAGLPVNGPREMSAEAYLPHML
RDKKVLAGEMRLVLPLALGKSEVRGGVPHDVVLSAIADCQQA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=362, Percent_Identity=93.646408839779, Blast_Score=675, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320332, Length=340, Percent_Identity=38.2352941176471, Blast_Score=194, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38912; Mature: 38912

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERITVTLGERSYPITIAAGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQA
CCEEEEEECCCCCCEEEEECCCCCCCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GVIVDSVILPDGEKYKSLTVLDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQR
CHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHC
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLQTLPARELAS
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCEEEEHHHHHCCCHHHHHH
GLAEVIKYGIILDGEFFTWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
HHHHHHHHCEEECCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLEQFSSADTQRIIALLERA
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
GLPVNGPREMSAEAYLPHMLRDKKVLAGEMRLVLPLALGKSEVRGGVPHDVVLSAIADCQ
CCCCCCCHHCCHHHHHHHHHHCCHHHHCCHHEEEEECCCHHHHCCCCCHHHHHHHHHHHH
QA
CC
>Mature Secondary Structure
MERITVTLGERSYPITIAAGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQA
CCEEEEEECCCCCCEEEEECCCCCCCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GVIVDSVILPDGEKYKSLTVLDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQR
CHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHC
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLQTLPARELAS
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCEEEEHHHHHCCCHHHHHH
GLAEVIKYGIILDGEFFTWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
HHHHHHHHCEEECCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLEQFSSADTQRIIALLERA
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
GLPVNGPREMSAEAYLPHMLRDKKVLAGEMRLVLPLALGKSEVRGGVPHDVVLSAIADCQ
CCCCCCCHHCCHHHHHHHHHHCCHHHHCCHHEEEEECCCHHHHCCCCCHHHHHHHHHHHH
QA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA