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The map label for this gene is rpe [H]

Identifier: 218550642

GI number: 218550642

Start: 3408717

End: 3409394

Strand: Reverse

Name: rpe [H]

Synonym: EFER_3352

Alternate gene names: 218550642

Gene position: 3409394-3408717 (Counterclockwise)

Preceding gene: 218550643

Following gene: 218550641

Centisome position: 74.3

GC content: 50.74

Gene sequence:

>678_bases
ATGAAACAGTATTTGATTGCCCCCTCAATTCTGTCGGCGGATTTTGCCCGCCTGGGTGAAGATACCGCAAAAGCCCTGGC
GGCGGGTGCAGATGTCGTGCATTTTGACGTCATGGATAACCACTATGTTCCCAATCTGACGATTGGACCGATGGTGCTGA
AATCTCTGCGTAATTATGGCATTACTGCCCCTATTGATGTGCATCTGATGGTGAAACCGGTCGATCGCATTGTGCCAGAT
TTCGCTGCCGCTGGTGCCAGCATCATTACCTTTCATCCAGAAGCCTCCGAGCATGTTGACCGCACGCTACAACTGATTAA
AGAAAATGGCTGTAAAGCGGGGCTGGTATTTAACCCGGCGACACCGCTGAGCTATCTGGATTACGTGATGGATAAGCTGG
ATGTGATCCTGCTGATGTCCGTCAACCCTGGTTTCGGCGGTCAGTCTTTCATTCCTCAAACACTGGATAAACTGCGCGAA
GTACGTCGTCGTATCGACGAGTCTGGCTTCGACATTCGACTGGAAGTGGACGGCGGCGTGAAGGTGAACAACATTGGCGA
AATCGCTGCGGCAGGTGCCGATATGTTCGTCGCTGGTTCGGCCATTTTCGATCAGCCAGACTACAAAAAGGTCATTGATG
ATATGCGCAGTGAACTGGCAAAGGTAAGTCATGAATAA

Upstream 100 bases:

>100_bases
GCAGCAACGGCGGCACACGTAAAAAGGTGGACGAACTGCTGGCTCTGTACAAACCAGGAGTCGTTTCACCCGCGAAAAAA
TAGTTCTCAAGGAGAAGCGG

Downstream 100 bases:

>100_bases
GTTTGAAGATATTCGCGGCGTCGCTTTTGATCTCGATGGTACGCTGGTCGACAGTGCTCCTGGTCTGGCTGCTGCGGTAG
ATATGGCGCTGTATGCGCTG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPD
FAAAGASIITFHPEASEHVDRTLQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDDMRSELAKVSHE

Sequences:

>Translated_225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPD
FAAAGASIITFHPEASEHVDRTLQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDDMRSELAKVSHE
>Mature_225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPD
FAAAGASIITFHPEASEHVDRTLQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDDMRSELAKVSHE

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=221, Percent_Identity=39.8190045248869, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI219879828, Length=221, Percent_Identity=38.4615384615385, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI24307923, Length=177, Percent_Identity=32.7683615819209, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1789788, Length=225, Percent_Identity=99.5555555555556, Blast_Score=456, Evalue=1e-130,
Organism=Escherichia coli, GI1790523, Length=197, Percent_Identity=37.5634517766497, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790754, Length=208, Percent_Identity=28.8461538461538, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17552948, Length=217, Percent_Identity=40.5529953917051, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322341, Length=233, Percent_Identity=38.6266094420601, Blast_Score=158, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24586301, Length=214, Percent_Identity=40.6542056074766, Blast_Score=158, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24541; Mature: 24541

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYG
CCCEECCHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
ITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRTLQLIKENGCKAGLVFNPA
CCCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCC
TPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRRRIDESGFDIRLEVDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCE
KVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDDMRSELAKVSHE
EECCCCHHHHCCCCCEEECCHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYG
CCCEECCHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
ITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRTLQLIKENGCKAGLVFNPA
CCCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCC
TPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRRRIDESGFDIRLEVDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCE
KVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDDMRSELAKVSHE
EECCCCHHHHCCCCCEEECCHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]