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The map label for this gene is pabA [H]

Identifier: 218550623

GI number: 218550623

Start: 3391264

End: 3391827

Strand: Reverse

Name: pabA [H]

Synonym: EFER_3333

Alternate gene names: 218550623

Gene position: 3391827-3391264 (Counterclockwise)

Preceding gene: 218550624

Following gene: 218550622

Centisome position: 73.92

GC content: 53.55

Gene sequence:

>564_bases
ATGATCCTGCTTATTGATAACTACGATTCTTTTACCTGGAACCTCTACCAGTACTTTTGTGAACTGGGGGCGGATGTGTT
GGTTAAGCGCAACGATGCGTTAACGTTGGCGGATATCGACACACTCAAACCGCAGAAAATTGTTATCTCACCTGGACCCT
GTACGCCGGACGACGCAGGGATCTCCCTTGACGTTATTCGCCACTACGCCGGGAGTTTGCCGATTCTTGGCGTCTGCCTC
GGTCATCAGGCAATGGCGCAGGCTTTTGGTGGCAAAGTTGTGCGCGCCGCAAAGGTGATGCACGGCAAAACCTCGCCGAT
CACACATAACGGTGAGGGCGTATTTAAGGGGCTGGCAAATCCACTCACCGTGACACGCTACCATTCGCTGGTGGTGGAGC
CTGACTCATTACCGGAGTGCTTTGAAGTGACGGCCTGGAGCGAAACCCGCGAGATTATGGGGATTCGCCATCGCCAGTGG
GATCTGGAAGGCGTACAGTTCCATCCAGAAAGTATTCTCAGCGAACAAGGGCATCAACTGCTGGCTAATTTCCTGGAGCG
CTGA

Upstream 100 bases:

>100_bases
ATGGGGGATCTCACCGCGCTGCAGATGATATTTAGCAAAGTGGTAAGCGAAGCCGGGGAATCTGAGTAAAATAGCGCGGT
TCTTTCGTACCGGAGCCGCC

Downstream 100 bases:

>100_bases
TTTCTGATTGCCATTCAGTGATTTTTTATGCATATTTTGTGATTATAATTTCACGTTGAGTTATGCGTAACAGGGTGATC
ATGAGATGGCAATTGAACAA

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDTLKPQKIVISPGPCTPDDAGISLDVIRHYAGSLPILGVCL
GHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFKGLANPLTVTRYHSLVVEPDSLPECFEVTAWSETREIMGIRHRQW
DLEGVQFHPESILSEQGHQLLANFLER

Sequences:

>Translated_187_residues
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDTLKPQKIVISPGPCTPDDAGISLDVIRHYAGSLPILGVCL
GHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFKGLANPLTVTRYHSLVVEPDSLPECFEVTAWSETREIMGIRHRQW
DLEGVQFHPESILSEQGHQLLANFLER
>Mature_187_residues
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDTLKPQKIVISPGPCTPDDAGISLDVIRHYAGSLPILGVCL
GHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFKGLANPLTVTRYHSLVVEPDSLPECFEVTAWSETREIMGIRHRQW
DLEGVQFHPESILSEQGHQLLANFLER

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=96.2566844919786, Blast_Score=379, Evalue=1e-107,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=43.3155080213904, Blast_Score=149, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=52.972972972973, Blast_Score=221, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=31.1320754716981, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 20755; Mature: 20755

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00442 GATASE_TYPE_I ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDTLKPQKIVISPGPCTPDDAG
CEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCEEEECCCCCCCCCCC
ISLDVIRHYAGSLPILGVCLGHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFKGLAN
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCC
PLTVTRYHSLVVEPDSLPECFEVTAWSETREIMGIRHRQWDLEGVQFHPESILSEQGHQL
CEEEEEEEEEEECCCCCCHHHEECCCHHHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHH
LANFLER
HHHHHCC
>Mature Secondary Structure
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDTLKPQKIVISPGPCTPDDAG
CEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCEEEECCCCCCCCCCC
ISLDVIRHYAGSLPILGVCLGHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFKGLAN
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCC
PLTVTRYHSLVVEPDSLPECFEVTAWSETREIMGIRHRQWDLEGVQFHPESILSEQGHQL
CEEEEEEEEEEECCCCCCHHHEECCCHHHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHH
LANFLER
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350604; 2403545; 9278503; 2546924; 8096767 [H]