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The map label for this gene is yagR [H]

Identifier: 218550133

GI number: 218550133

Start: 2887831

End: 2890029

Strand: Direct

Name: yagR [H]

Synonym: EFER_2821

Alternate gene names: 218550133

Gene position: 2887831-2890029 (Clockwise)

Preceding gene: 218550132

Following gene: 218550134

Centisome position: 62.93

GC content: 52.52

Gene sequence:

>2199_bases
ATGAAATTTGATAAACCAGCAGGTCAAAACCCTGTTGATCGGCTCCTGGTTGTCGGTCATCCTCATGACCGCATTGATGG
TAAACGTAAAGTCACTGGTACTGCTCCGTACGCCTGGGAATGGCATGATGAAGCCACAAAAGTTGCGTATGGCTACATTG
TGACCTCAGCTATCGCCAAAGGTCGGATTACATCACTCGACACACACAATGCGGACAACGCACCTGGTGTGCTGGCGGTA
GTTACGGCACAAAATGCCGGGCCACTCGGTAAAGGAGAACAAAACACAGCTACACTGCTCGGTGGCCCGGAAATTGAACA
CTACCATCAGGCTATTGCGCTGGTAGTGGCTGAAACGTTTGAACAGGCGCGAGCTGCTGCTTCTCTGGTTCAGGTGCAAT
ATGAACAGCAAGCTGGTGAGTATGATCTTGCCGCAGCCATACCCAATGCCACTGCGCCCCCCGAATATGAAGAAGATAAA
ACAACGGGTGACTTCGCCAGTGCCTTTGCAGGTGCTGCGATAACCCTTGATGCAACCTACACCACGCCGGATCAAAGCCA
TATGGCAATGGAACCCCATGCATCATTAGCTTTCTGGCATGGCGATCAACTAACGATCCGCACTTCCAATCAGATGATCG
ACTGGTGTCGTAGCGATCTGGCGAAAACGCTAAAAATACCAAAGGAAAAGATCCGCGTGTTATCGCCGTGGATCGGCGGC
GGTTTTGGCGGAAAACTGTTTCTGCGCAGTGATGCCCTACTGGCAGCGATTGGCGCAAGAATGATCCAGCGTCCGGTGAA
AGTGATGCTCCCTCGCCCTGTCATAGCAAATAACACCACCCATCGCCCGGCAACCATTCAGCGTATTCGTCTTGGCACCG
ATATTGAAGGACGTATTTGCGCAATTTCGCATAAAAGTTATTCCGGCAATCTGCCCGGCGGCACTCCAGAAATCGCCGTT
CAACAAAGTGAACTTCTGTATGCAGGAGCTCATCGTCATACCGGATTGCGACTGGCAAAACTCGATCTTCCTGAGGGCAA
TGCCATGCGTGCCCCCGGCGAAACGCCGGGATTGATGGCTCTGGAGATCGCTATCGATGAAATTGCGGAAAAAGCGGGCC
TCGATCCTGTAGAGTTCCGCATACTTAACGACACACAAGTTGATCCCGCTAACCCGAATCGCCCCTTCTCGCGTCGTCAA
TTGGTTGAATGCCTGCGCACGGGTGCAGACCGTTTTGGCTGGAGCAAACGCAACGCCAGACCAGGACAAAACAAAGAAGG
TGAATGGCTGACAGGAATGGGAATGGCGGCTGGTTTTCGCAATAATTTGCTGACCCCTTCCGGGGCACGTGTGCATCTGG
AGTTGGACGGTACGCTTACGGTTGAAACCGATATGACGGATATCGGTACGGGCAGTTACACCATCATTGCCCAGACTGCC
GCCGAAATGTTGGGGCTGCCACTGGAAAAAGTGAATGTGCACCTTGGTGATTCCAGTTTTCCGATATCCGGTGGTTCGGG
CGGACAATGGGGAGCCAACACATCGACATCGGGCGTTTATGCTGCCTGCGTCAAACTACGTGAAGCCATTGCTAAAAAGC
TGGGATTTGCGCCCGACGATACGGAGTTTACCGGCGAGAAGGTGCATTGTGGTGAGCGTCATGCGCGTTTAACGGATGCA
CTCAACAACGGCAGAATCAGCGCGCAGGATCAGATTGAATTTGGCGATCTGGATGAACAGTTCCAGCAATCCACTTTTGC
CGGGCATTTTATTGAAGTTGCTGTACACCGGATGACCGGTGAGATTCGTGTACGACGAATGTTGGCAGTATGTGCTGCCG
GGCGAATTCTTAACCCCAAAACAGCACGTAGCCAGGTGATTGGTGCTATGACCATGGGCCTGGGTGCGGCATTAATGGAG
GAGTTGTTGGTTGATACTCGCCAGGGTTATTTCGTTAATCATGATATGGCGAGCTATGAGATCCCGGTACATGCTGACAT
CCCCCTTCAGGAAGTGATCTTCCTGGATGATACAGATCCCGTCTCATCGCCTGTGAAAGCCAAAGGGGTAGGAGAACTGG
GGCTTTGCGGCGTCAGCGCGGCAATTGCCAACGCGATTTATAACGCCACCGGTGTACGCCGACGAGATTACCCCATTACG
CCAGATAAACTCCTGTGCGCCCTTCCTGATCGCTTGTGA

Upstream 100 bases:

>100_bases
AACTGTTCGCTACTGCCCACCCGACTGCAGAAAATGAATACAAGCTCATTCTGGCGAAGCGCACACTCGCCTCAGTATTA
ACGCAAGCGGGAGTAACACG

Downstream 100 bases:

>100_bases
GGTTAAACCATGTTGCAAAAGGTCACTCACAATCACATTTTAGCCACGCCAAAGCAGGCACTGCTAACCGATGACCGTCA
GAGGGTTTTACGTTTTGCTG

Product: xanthine dehydrogenase, molybdenum binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MKFDKPAGQNPVDRLLVVGHPHDRIDGKRKVTGTAPYAWEWHDEATKVAYGYIVTSAIAKGRITSLDTHNADNAPGVLAV
VTAQNAGPLGKGEQNTATLLGGPEIEHYHQAIALVVAETFEQARAAASLVQVQYEQQAGEYDLAAAIPNATAPPEYEEDK
TTGDFASAFAGAAITLDATYTTPDQSHMAMEPHASLAFWHGDQLTIRTSNQMIDWCRSDLAKTLKIPKEKIRVLSPWIGG
GFGGKLFLRSDALLAAIGARMIQRPVKVMLPRPVIANNTTHRPATIQRIRLGTDIEGRICAISHKSYSGNLPGGTPEIAV
QQSELLYAGAHRHTGLRLAKLDLPEGNAMRAPGETPGLMALEIAIDEIAEKAGLDPVEFRILNDTQVDPANPNRPFSRRQ
LVECLRTGADRFGWSKRNARPGQNKEGEWLTGMGMAAGFRNNLLTPSGARVHLELDGTLTVETDMTDIGTGSYTIIAQTA
AEMLGLPLEKVNVHLGDSSFPISGGSGGQWGANTSTSGVYAACVKLREAIAKKLGFAPDDTEFTGEKVHCGERHARLTDA
LNNGRISAQDQIEFGDLDEQFQQSTFAGHFIEVAVHRMTGEIRVRRMLAVCAAGRILNPKTARSQVIGAMTMGLGAALME
ELLVDTRQGYFVNHDMASYEIPVHADIPLQEVIFLDDTDPVSSPVKAKGVGELGLCGVSAAIANAIYNATGVRRRDYPIT
PDKLLCALPDRL

Sequences:

>Translated_732_residues
MKFDKPAGQNPVDRLLVVGHPHDRIDGKRKVTGTAPYAWEWHDEATKVAYGYIVTSAIAKGRITSLDTHNADNAPGVLAV
VTAQNAGPLGKGEQNTATLLGGPEIEHYHQAIALVVAETFEQARAAASLVQVQYEQQAGEYDLAAAIPNATAPPEYEEDK
TTGDFASAFAGAAITLDATYTTPDQSHMAMEPHASLAFWHGDQLTIRTSNQMIDWCRSDLAKTLKIPKEKIRVLSPWIGG
GFGGKLFLRSDALLAAIGARMIQRPVKVMLPRPVIANNTTHRPATIQRIRLGTDIEGRICAISHKSYSGNLPGGTPEIAV
QQSELLYAGAHRHTGLRLAKLDLPEGNAMRAPGETPGLMALEIAIDEIAEKAGLDPVEFRILNDTQVDPANPNRPFSRRQ
LVECLRTGADRFGWSKRNARPGQNKEGEWLTGMGMAAGFRNNLLTPSGARVHLELDGTLTVETDMTDIGTGSYTIIAQTA
AEMLGLPLEKVNVHLGDSSFPISGGSGGQWGANTSTSGVYAACVKLREAIAKKLGFAPDDTEFTGEKVHCGERHARLTDA
LNNGRISAQDQIEFGDLDEQFQQSTFAGHFIEVAVHRMTGEIRVRRMLAVCAAGRILNPKTARSQVIGAMTMGLGAALME
ELLVDTRQGYFVNHDMASYEIPVHADIPLQEVIFLDDTDPVSSPVKAKGVGELGLCGVSAAIANAIYNATGVRRRDYPIT
PDKLLCALPDRL
>Mature_732_residues
MKFDKPAGQNPVDRLLVVGHPHDRIDGKRKVTGTAPYAWEWHDEATKVAYGYIVTSAIAKGRITSLDTHNADNAPGVLAV
VTAQNAGPLGKGEQNTATLLGGPEIEHYHQAIALVVAETFEQARAAASLVQVQYEQQAGEYDLAAAIPNATAPPEYEEDK
TTGDFASAFAGAAITLDATYTTPDQSHMAMEPHASLAFWHGDQLTIRTSNQMIDWCRSDLAKTLKIPKEKIRVLSPWIGG
GFGGKLFLRSDALLAAIGARMIQRPVKVMLPRPVIANNTTHRPATIQRIRLGTDIEGRICAISHKSYSGNLPGGTPEIAV
QQSELLYAGAHRHTGLRLAKLDLPEGNAMRAPGETPGLMALEIAIDEIAEKAGLDPVEFRILNDTQVDPANPNRPFSRRQ
LVECLRTGADRFGWSKRNARPGQNKEGEWLTGMGMAAGFRNNLLTPSGARVHLELDGTLTVETDMTDIGTGSYTIIAQTA
AEMLGLPLEKVNVHLGDSSFPISGGSGGQWGANTSTSGVYAACVKLREAIAKKLGFAPDDTEFTGEKVHCGERHARLTDA
LNNGRISAQDQIEFGDLDEQFQQSTFAGHFIEVAVHRMTGEIRVRRMLAVCAAGRILNPKTARSQVIGAMTMGLGAALME
ELLVDTRQGYFVNHDMASYEIPVHADIPLQEVIFLDDTDPVSSPVKAKGVGELGLCGVSAAIANAIYNATGVRRRDYPIT
PDKLLCALPDRL

Specific function: Unknown

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=775, Percent_Identity=26.9677419354839, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI71773480, Length=767, Percent_Identity=25.4237288135593, Blast_Score=157, Evalue=3e-38,
Organism=Escherichia coli, GI1786478, Length=730, Percent_Identity=76.1643835616438, Blast_Score=1132, Evalue=0.0,
Organism=Escherichia coli, GI1789230, Length=756, Percent_Identity=28.8359788359788, Blast_Score=240, Evalue=3e-64,
Organism=Escherichia coli, GI1789246, Length=818, Percent_Identity=26.161369193154, Blast_Score=190, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17540638, Length=755, Percent_Identity=25.1655629139073, Blast_Score=156, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI32566215, Length=556, Percent_Identity=24.6402877697842, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24647193, Length=749, Percent_Identity=24.56608811749, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17737937, Length=734, Percent_Identity=25.0681198910082, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24647199, Length=747, Percent_Identity=22.3560910307898, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24647201, Length=743, Percent_Identity=23.4185733512786, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24647195, Length=735, Percent_Identity=23.9455782312925, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24647197, Length=726, Percent_Identity=23.9669421487603, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 78933; Mature: 78933

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDKPAGQNPVDRLLVVGHPHDRIDGKRKVTGTAPYAWEWHDEATKVAYGYIVTSAIAK
CCCCCCCCCCHHHEEEEEECCCHHCCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHHC
GRITSLDTHNADNAPGVLAVVTAQNAGPLGKGEQNTATLLGGPEIEHYHQAIALVVAETF
CCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
EQARAAASLVQVQYEQQAGEYDLAAAIPNATAPPEYEEDKTTGDFASAFAGAAITLDATY
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEE
TTPDQSHMAMEPHASLAFWHGDQLTIRTSNQMIDWCRSDLAKTLKIPKEKIRVLSPWIGG
CCCCCCCEEECCCCCEEEEECCEEEEEECHHHHHHHHHHHHHHHHCCHHHHHEECCCCCC
GFGGKLFLRSDALLAAIGARMIQRPVKVMLPRPVIANNTTHRPATIQRIRLGTDIEGRIC
CCCCEEEEECCHHHHHHHHHHHHCCHHHHCCCCEECCCCCCCCCEEEEEEECCCCCCCEE
AISHKSYSGNLPGGTPEIAVQQSELLYAGAHRHTGLRLAKLDLPEGNAMRAPGETPGLMA
EEEECCCCCCCCCCCCCEEEECCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
LEIAIDEIAEKAGLDPVEFRILNDTQVDPANPNRPFSRRQLVECLRTGADRFGWSKRNAR
EHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCC
PGQNKEGEWLTGMGMAAGFRNNLLTPSGARVHLELDGTLTVETDMTDIGTGSYTIIAQTA
CCCCCCCCEEECCCHHHHHHCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCEEEEHHHH
AEMLGLPLEKVNVHLGDSSFPISGGSGGQWGANTSTSGVYAACVKLREAIAKKLGFAPDD
HHHHCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
TEFTGEKVHCGERHARLTDALNNGRISAQDQIEFGDLDEQFQQSTFAGHFIEVAVHRMTG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EIRVRRMLAVCAAGRILNPKTARSQVIGAMTMGLGAALMEELLVDTRQGYFVNHDMASYE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEE
IPVHADIPLQEVIFLDDTDPVSSPVKAKGVGELGLCGVSAAIANAIYNATGVRRRDYPIT
EEEECCCCHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
PDKLLCALPDRL
HHHHHCCCCCCC
>Mature Secondary Structure
MKFDKPAGQNPVDRLLVVGHPHDRIDGKRKVTGTAPYAWEWHDEATKVAYGYIVTSAIAK
CCCCCCCCCCHHHEEEEEECCCHHCCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHHC
GRITSLDTHNADNAPGVLAVVTAQNAGPLGKGEQNTATLLGGPEIEHYHQAIALVVAETF
CCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
EQARAAASLVQVQYEQQAGEYDLAAAIPNATAPPEYEEDKTTGDFASAFAGAAITLDATY
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEE
TTPDQSHMAMEPHASLAFWHGDQLTIRTSNQMIDWCRSDLAKTLKIPKEKIRVLSPWIGG
CCCCCCCEEECCCCCEEEEECCEEEEEECHHHHHHHHHHHHHHHHCCHHHHHEECCCCCC
GFGGKLFLRSDALLAAIGARMIQRPVKVMLPRPVIANNTTHRPATIQRIRLGTDIEGRIC
CCCCEEEEECCHHHHHHHHHHHHCCHHHHCCCCEECCCCCCCCCEEEEEEECCCCCCCEE
AISHKSYSGNLPGGTPEIAVQQSELLYAGAHRHTGLRLAKLDLPEGNAMRAPGETPGLMA
EEEECCCCCCCCCCCCCEEEECCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
LEIAIDEIAEKAGLDPVEFRILNDTQVDPANPNRPFSRRQLVECLRTGADRFGWSKRNAR
EHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCC
PGQNKEGEWLTGMGMAAGFRNNLLTPSGARVHLELDGTLTVETDMTDIGTGSYTIIAQTA
CCCCCCCCEEECCCHHHHHHCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCEEEEHHHH
AEMLGLPLEKVNVHLGDSSFPISGGSGGQWGANTSTSGVYAACVKLREAIAKKLGFAPDD
HHHHCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
TEFTGEKVHCGERHARLTDALNNGRISAQDQIEFGDLDEQFQQSTFAGHFIEVAVHRMTG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EIRVRRMLAVCAAGRILNPKTARSQVIGAMTMGLGAALMEELLVDTRQGYFVNHDMASYE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEE
IPVHADIPLQEVIFLDDTDPVSSPVKAKGVGELGLCGVSAAIANAIYNATGVRRRDYPIT
EEEECCCCHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
PDKLLCALPDRL
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]