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The map label for this gene is uxuR [H]

Identifier: 218549980

GI number: 218549980

Start: 2741864

End: 2742535

Strand: Direct

Name: uxuR [H]

Synonym: EFER_2665

Alternate gene names: 218549980

Gene position: 2741864-2742535 (Clockwise)

Preceding gene: 218549979

Following gene: 218549986

Centisome position: 59.75

GC content: 39.73

Gene sequence:

>672_bases
ATGCTAATTCCAGAAATTAAACAGGAAAGGCTCTATCAAAAGATAGCGAATCTTATTATTAAGCTCATCAATGATAATGT
GTTTCCACCAGGTAGCTTTTTACCTCCAGAACGTGAACTGGCGAAACAACTGGGGGTTAGTCGTTCATCGCTAAGAGAAG
CGCTTATAGTTCTGGAGATATCTGGCTGGATTATTATTCAGTCTGGAAATGGGGTGATTGTCAGCGATAAAAAACACCCT
CCTGTCGATTACACTATCGAAGAAATTCTTTATACCCGTGATTTAGTTGATAGTCATTGTGCCCGACTTGCAGCACTGGC
TAATAATGAAACAATGATTAATAAAATTGAGGCACTTTATTTACGAATGGAAAATGCCATTAACGAAAATAATGTGGCTG
AATTTTATACGCTTGATAAGCAGTTTCATCTGGCCATTTCTGAAGCCAGTCATAATCGGGTGTTATTAGATATGTCACGG
ATGCTTTGGGAGCAGCGCATCAATATACCCTATGCCGGGCTGGATAAACGTTCCGGCGATAAGAATGTACTTATCAACCT
TAATCAACAGCATAAAGCAATCATTGAGGCGATTCGTGCAGGAGATGCAGACAATGCCTTGCAACAGGCACTGCTACATT
TGAAGTATGTGCGAGAAATAATTGGTTATTAA

Upstream 100 bases:

>100_bases
GGCTGATTTTTCGTCATTGTCACTCGAAAGCAGTAGATCCGAACCAGGGATGGTATGATAATTCGTCGGATAACTAACGA
TAAAATCGAGCGGGAGGCAC

Downstream 100 bases:

>100_bases
CCTTTTCTGCGCTAAAAAAACGCGTAGTGAATTCACTACGCGTTTTGATTTTTGCTAATTAAATGAATTTCACGTTAATT
TTCAGATGGCGTTCCGGGAA

Product: gntR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MLIPEIKQERLYQKIANLIIKLINDNVFPPGSFLPPERELAKQLGVSRSSLREALIVLEISGWIIIQSGNGVIVSDKKHP
PVDYTIEEILYTRDLVDSHCARLAALANNETMINKIEALYLRMENAINENNVAEFYTLDKQFHLAISEASHNRVLLDMSR
MLWEQRINIPYAGLDKRSGDKNVLINLNQQHKAIIEAIRAGDADNALQQALLHLKYVREIIGY

Sequences:

>Translated_223_residues
MLIPEIKQERLYQKIANLIIKLINDNVFPPGSFLPPERELAKQLGVSRSSLREALIVLEISGWIIIQSGNGVIVSDKKHP
PVDYTIEEILYTRDLVDSHCARLAALANNETMINKIEALYLRMENAINENNVAEFYTLDKQFHLAISEASHNRVLLDMSR
MLWEQRINIPYAGLDKRSGDKNVLINLNQQHKAIIEAIRAGDADNALQQALLHLKYVREIIGY
>Mature_223_residues
MLIPEIKQERLYQKIANLIIKLINDNVFPPGSFLPPERELAKQLGVSRSSLREALIVLEISGWIIIQSGNGVIVSDKKHP
PVDYTIEEILYTRDLVDSHCARLAALANNETMINKIEALYLRMENAINENNVAEFYTLDKQFHLAISEASHNRVLLDMSR
MLWEQRINIPYAGLDKRSGDKNVLINLNQQHKAIIEAIRAGDADNALQQALLHLKYVREIIGY

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=227, Percent_Identity=34.8017621145374, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1790032, Length=221, Percent_Identity=33.0316742081448, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786303, Length=238, Percent_Identity=31.0924369747899, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI87082208, Length=219, Percent_Identity=28.7671232876712, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1789353, Length=210, Percent_Identity=32.3809523809524, Blast_Score=77, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25409; Mature: 25409

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIPEIKQERLYQKIANLIIKLINDNVFPPGSFLPPERELAKQLGVSRSSLREALIVLEI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHEEEEEEE
SGWIIIQSGNGVIVSDKKHPPVDYTIEEILYTRDLVDSHCARLAALANNETMINKIEALY
CCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LRMENAINENNVAEFYTLDKQFHLAISEASHNRVLLDMSRMLWEQRINIPYAGLDKRSGD
HHHHHHCCCCCCHHHEEECCCEEEEEECCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCC
KNVLINLNQQHKAIIEAIRAGDADNALQQALLHLKYVREIIGY
CEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLIPEIKQERLYQKIANLIIKLINDNVFPPGSFLPPERELAKQLGVSRSSLREALIVLEI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHEEEEEEE
SGWIIIQSGNGVIVSDKKHPPVDYTIEEILYTRDLVDSHCARLAALANNETMINKIEALY
CCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LRMENAINENNVAEFYTLDKQFHLAISEASHNRVLLDMSRMLWEQRINIPYAGLDKRSGD
HHHHHHCCCCCCHHHEEECCCEEEEEECCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCC
KNVLINLNQQHKAIIEAIRAGDADNALQQALLHLKYVREIIGY
CEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]