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The map label for this gene is dcuC [H]

Identifier: 218549801

GI number: 218549801

Start: 2544237

End: 2545625

Strand: Direct

Name: dcuC [H]

Synonym: EFER_2482

Alternate gene names: 218549801

Gene position: 2544237-2545625 (Clockwise)

Preceding gene: 218549798

Following gene: 218549802

Centisome position: 55.45

GC content: 48.09

Gene sequence:

>1389_bases
TTGAACACAGGGGAAACAATGTTAACTTTTATCGAACTCCTGATTGGGGTAATCGTTATAGTGGGTGTTGCCCGCTACAT
TATTAAGGGGTATTCCGCCACTGGCGTACTCTTTGTCGGCGGTCTGGCGTTATTGATTATTAGCGCTTTGATGGGCCACA
AAGTACTGCCGTCCAGCGCCACCAGTACTGGTTACTCAGCGACTGATATCGTTGAATATATTAAGATATTACTGATGAGT
CGTGGCGGCGACCTTGGCATGATGATTATGATGTTGTGCGGATTTGCTGCGTACATGACTCATATTGGTGCCAATGATAT
GGTTGTAAAGCTGGCTTCCAAACCATTGCAGTATATTAACTCGCCTTATTTGCTGATGATTGCAGCTTATTTTGTCGCTT
GCCTGATGTCTCTTGCGGTTTCCTCTGCGACAGGGCTTGGTGTGTTGTTAATGGCGACCTTATTCCCGGTAATGGTTAAC
GTTGGTATCAGTCGTGGTGCGGCGGCCGCTATATGTGCCTCTCCTGCGGCAATCATTCTTTCTCCAACTTCTGGCGATGT
GGTTCTGGCAGCAGAAGCCGCAGAAATGCCATTAATTGATTTTGCCTTTAAAACAACGCTGCCCATTTCTATAGCGGCAA
TCATTGGTATGGCGATTGCCCACTTTTTCTGGCAGCGCTATCTCGATAAGAAAGAACATATCTCCCATGAGATGCTGGAC
GTCAACGAAATCACCACTACGGCTCCGGCGTTTTACGCCATTCTGCCGTTTACCCCGATCATCGGTGTTCTGATTTTTGA
CGGCAAATGGGGGCCACAGCTGCACATCATTACCATTCTGGTTATTTGTATGTTGTTAGCTGCCGTACTGGAATTTGTTC
GTGGTTTTGATACCCAGAAAGTCTTCTCCGGGCTGGAAGTGGCGTATCGCGGCATGGCAGATGCGTTTGCCAGTGTAGTA
ATGTTGTTGGTTGCTGCCGGGGTTTTTGCTCAAGGGTTGAGCACAATCGGCTTTATCCAGAGCTTGATTTCCATTGCCAC
CTCATTTGGCTCGGCAAGCATTATTCTGATGCTGGTTCTGGTAATTTTAACCATGCTGGCAGCGATGACCACCGGATCGG
GTAATGCGCCGTTCTATGCTTTTGTTGAGATGATCCCCAAACTGGCCCATTCATCAGGAATCAATCCGGCTTATTTATCG
ATTCCTATGCTACAGGCATCCAACCTGGGACGTACCATCTCACCGGTTTCTGGCGTGGTTGTTGCAGTGGCAGGGATGGC
AAAAATCTCCCCCTTCGAAGTAGTAAAACGCACTTCTGTACCGGTACTGGTGGGGTTATTGATTGTGATAATCGCCACTG
AGATCCTGGTTCCTGGAGCTGCAGCCTAA

Upstream 100 bases:

>100_bases
TAATTTTCTGAAAATTGATTTTAATCAGCAAGCTCCTGTCGTTTATTAGGCATATTCCCCTTTCAATTAAGATTTTTTTA
CTTTTTAAATTTTTGGTGAC

Downstream 100 bases:

>100_bases
AAATGCGTCGCCGGAGGCCTCTCCGGCGCGCTCCTTCTTAACCATGGTAAATACGCTGCGGTCCATGAATGAAAAAATGA
TTAGCCATACTGGCTGGTCG

Product: C4-dicarboxylate transporter DcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNTGETMLTFIELLIGVIVIVGVARYIIKGYSATGVLFVGGLALLIISALMGHKVLPSSATSTGYSATDIVEYIKILLMS
RGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVN
VGISRGAAAAICASPAAIILSPTSGDVVLAAEAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKEHISHEMLD
VNEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFDTQKVFSGLEVAYRGMADAFASVV
MLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLS
IPMLQASNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLLIVIIATEILVPGAAA

Sequences:

>Translated_462_residues
MNTGETMLTFIELLIGVIVIVGVARYIIKGYSATGVLFVGGLALLIISALMGHKVLPSSATSTGYSATDIVEYIKILLMS
RGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVN
VGISRGAAAAICASPAAIILSPTSGDVVLAAEAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKEHISHEMLD
VNEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFDTQKVFSGLEVAYRGMADAFASVV
MLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLS
IPMLQASNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLLIVIIATEILVPGAAA
>Mature_462_residues
MNTGETMLTFIELLIGVIVIVGVARYIIKGYSATGVLFVGGLALLIISALMGHKVLPSSATSTGYSATDIVEYIKILLMS
RGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVN
VGISRGAAAAICASPAAIILSPTSGDVVLAAEAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKEHISHEMLD
VNEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFDTQKVFSGLEVAYRGMADAFASVV
MLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLS
IPMLQASNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLLIVIIATEILVPGAAA

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=456, Percent_Identity=94.2982456140351, Blast_Score=724, Evalue=0.0,
Organism=Escherichia coli, GI1789622, Length=447, Percent_Identity=35.7941834451902, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 48485; Mature: 48485

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTGETMLTFIELLIGVIVIVGVARYIIKGYSATGVLFVGGLALLIISALMGHKVLPSSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
TSTGYSATDIVEYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYIN
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
SPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAICASPAAIIL
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEE
SPTSGDVVLAAEAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKEHISHEMLD
ECCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
VNEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFDTQK
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
VFSGLEVAYRGMADAFASVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQASNLGRTISPVSGVV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEHHHHCCCCCCCCHHHHHH
VAVAGMAKISPFEVVKRTSVPVLVGLLIVIIATEILVPGAAA
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNTGETMLTFIELLIGVIVIVGVARYIIKGYSATGVLFVGGLALLIISALMGHKVLPSSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
TSTGYSATDIVEYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYIN
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
SPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAICASPAAIIL
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEE
SPTSGDVVLAAEAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKEHISHEMLD
ECCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
VNEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFDTQK
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
VFSGLEVAYRGMADAFASVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQASNLGRTISPVSGVV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEHHHHCCCCCCCCHHHHHH
VAVAGMAKISPFEVVKRTSVPVLVGLLIVIIATEILVPGAAA
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]