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The map label for this gene is rcsA [H]

Identifier: 218549276

GI number: 218549276

Start: 1986438

End: 1987061

Strand: Direct

Name: rcsA [H]

Synonym: EFER_1936

Alternate gene names: 218549276

Gene position: 1986438-1987061 (Clockwise)

Preceding gene: 218549275

Following gene: 218549278

Centisome position: 43.29

GC content: 37.98

Gene sequence:

>624_bases
ATGTCAACGATTATTATGGATCTATGCAGTTACACCCGGCTGGGTTTGACCGGGTATCTTGTTAGCAGAGGGGTTAAGAA
AAGGGAAATCAACGACATCGAAAGCGTTGATCAACTTAAGGTCGCTTGTGACTTACATCATCCTTCAGTGGTGTTTATTA
ATGAAGACTGTTTTATCCATGACCCGGCAAACAGTCAGCACATCAAGCAAATCATTAATCAACATCCCAACACTTTATTT
ATTGTATTTATGGCGATTGCCAATATCCATTTTGATGAGTATCTGCTTGTCCGCAAAAATTTATTGATCAGTTCCAAGTC
GATTAAACCGGAATCTCTTGACGATATCCTTGGCGATATTCTGAAAAAAGAGGTCGATATTGCCAGTGTAATTAATTTAC
CCACGTTATCATTAAGTCGAACTGAATCAAGCATGTTACGTATGTGGATGGCAGGCCAGGGTACGATTCAGATTTCTGAC
CAGATGAATATCAAGGCTAAAACGGTATCGTCACACAAGGGAAATATTAAACGTAAGATTAAAACGCATAATAAACAGGT
TATTTATCATGTGGTACGTTTAACAGACAATGTAACTAACGGTATATTTGTTAATATGCGCTAA

Upstream 100 bases:

>100_bases
CCTGAAAAATCGCGTAAAGCGTCACCTGAGGTCATTAATTATTTCTACAACGATATTCAGGTAAGGGGAATTATCGTTAC
GCATTGAGTGAGGGTATGCC

Downstream 100 bases:

>100_bases
TAGCTGCTGACTGGTGGCTACACCACCAGTCAGATGTACTCGCTGCCCTATTCCATTTTCTCGACAAAAATACCATCCGG
GTGCCCTGACTCATTAAAGA

Product: DNA-binding transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSTIIMDLCSYTRLGLTGYLVSRGVKKREINDIESVDQLKVACDLHHPSVVFINEDCFIHDPANSQHIKQIINQHPNTLF
IVFMAIANIHFDEYLLVRKNLLISSKSIKPESLDDILGDILKKEVDIASVINLPTLSLSRTESSMLRMWMAGQGTIQISD
QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR

Sequences:

>Translated_207_residues
MSTIIMDLCSYTRLGLTGYLVSRGVKKREINDIESVDQLKVACDLHHPSVVFINEDCFIHDPANSQHIKQIINQHPNTLF
IVFMAIANIHFDEYLLVRKNLLISSKSIKPESLDDILGDILKKEVDIASVINLPTLSLSRTESSMLRMWMAGQGTIQISD
QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR
>Mature_206_residues
STIIMDLCSYTRLGLTGYLVSRGVKKREINDIESVDQLKVACDLHHPSVVFINEDCFIHDPANSQHIKQIINQHPNTLFI
VFMAIANIHFDEYLLVRKNLLISSKSIKPESLDDILGDILKKEVDIASVINLPTLSLSRTESSMLRMWMAGQGTIQISDQ
MNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR

Specific function: Positive regulator of capsular polysaccharide synthesis. RcsA and rcsB form a complex to promote transcription of the genes for capsule synthesis [H]

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788262, Length=207, Percent_Identity=90.8212560386473, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 23497; Mature: 23366

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIIMDLCSYTRLGLTGYLVSRGVKKREINDIESVDQLKVACDLHHPSVVFINEDCFIH
CCHHHHHHHHHHHHCHHHHHHHCCCCHHHCCCHHHHHHHEEEEECCCCEEEEEECCEEEE
DPANSQHIKQIINQHPNTLFIVFMAIANIHFDEYLLVRKNLLISSKSIKPESLDDILGDI
CCCCHHHHHHHHHCCCCEEEHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
LKKEVDIASVINLPTLSLSRTESSMLRMWMAGQGTIQISDQMNIKAKTVSSHKGNIKRKI
HHHHCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCHHHHH
KTHNKQVIYHVVRLTDNVTNGIFVNMR
HHCCHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
STIIMDLCSYTRLGLTGYLVSRGVKKREINDIESVDQLKVACDLHHPSVVFINEDCFIH
CHHHHHHHHHHHHCHHHHHHHCCCCHHHCCCHHHHHHHEEEEECCCCEEEEEECCEEEE
DPANSQHIKQIINQHPNTLFIVFMAIANIHFDEYLLVRKNLLISSKSIKPESLDDILGDI
CCCCHHHHHHHHHCCCCEEEHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
LKKEVDIASVINLPTLSLSRTESSMLRMWMAGQGTIQISDQMNIKAKTVSSHKGNIKRKI
HHHHCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCCCHHHHH
KTHNKQVIYHVVRLTDNVTNGIFVNMR
HHCCHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]