Click here to switch to the map view.

The map label for this gene is pabC [H]

Identifier: 218549177

GI number: 218549177

Start: 1884641

End: 1885456

Strand: Reverse

Name: pabC [H]

Synonym: EFER_1831

Alternate gene names: 218549177

Gene position: 1885456-1884641 (Counterclockwise)

Preceding gene: 218549178

Following gene: 218549176

Centisome position: 41.09

GC content: 47.18

Gene sequence:

>816_bases
ATGTTCTTAATAAATGGTCAAAAACAAACATGGCTGGCCGCGAGTGACAGAGCGACGCAGTTTGGTGATGGATGTTTCAC
CACCGCACGTATTCAGGATGGACATGTAATTATGCTCACAGAGCATATCCGGCGATTACAGGATGCCTGCATTAAATTGA
TGATTACCTTTGAGCAGTGGGAGTTACTGCAACTGGAAATGGAAACTCTGGCAAGGGAACATAAAAGTGGTGTGCTTAAG
GTGATTATCACTCGTGGTAGTGGTGGTCGTGGTTACAGTCCTGGCAGTTGTCACTCACCAGGCCGAATTTTGTCCGTTTC
TGCATATCCAGAGCATTATTCCCGCTGGCGACAGAAGGGAATTACGCTAACTCTCAGCCCTGTTCGCCTGGGCCGCAATC
CCTTACTTGCAGGAATTAAGCATCTTAATCGGCTGGAGCAAGTGTTGATCCGGACACATCTCGATCAGACAACTGCTGAC
GAGGCACTTGTTCTTGACAGCGAAGGATGGGTTACGGAATGCTGCGCAGCTAATTTATTCTGGCGACAGGGAAATGTGGT
TTATACACCGAGCCTTGAATATGCCGGTGTGAAGGGCATTATGCGACAATTCTGTATCCATTTATTGGCACAATCTTCTT
ATCGTGTTGTCGAAGTTCAGGCTCGACCGGAAGAGGTAATGGCGGCAGATGAAATTTTGCTTTGTAATGCGCTGATGCCC
GTCATTCCCGTACGCACCTGTGGTGATAAGTTGCTGTCTTCGAGACAATTATTTGAGTTTTTAGCCCCACTTTGTGAGCA
CCCGAATTCATTATGA

Upstream 100 bases:

>100_bases
TATTAAAGGTCCGCTTGCGGGCCTTTTTTCATGTATATGCAACAGACTTGTCCTGATGTGTTCAAACTGCCAAACTTATT
CAAAACGATAGGGAGCCAGT

Downstream 100 bases:

>100_bases
AAAAATTGTTATTTGTCCTTTTGCTGTTGTTGATTGTACTGGGCATTGCCGCAGGCGTGGGCATGTGGAAAGTTCGTCAG
TTCGCTGACAGTAAATTGTT

Product: Aminodeoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MFLINGQKQTWLAASDRATQFGDGCFTTARIQDGHVIMLTEHIRRLQDACIKLMITFEQWELLQLEMETLAREHKSGVLK
VIITRGSGGRGYSPGSCHSPGRILSVSAYPEHYSRWRQKGITLTLSPVRLGRNPLLAGIKHLNRLEQVLIRTHLDQTTAD
EALVLDSEGWVTECCAANLFWRQGNVVYTPSLEYAGVKGIMRQFCIHLLAQSSYRVVEVQARPEEVMAADEILLCNALMP
VIPVRTCGDKLLSSRQLFEFLAPLCEHPNSL

Sequences:

>Translated_271_residues
MFLINGQKQTWLAASDRATQFGDGCFTTARIQDGHVIMLTEHIRRLQDACIKLMITFEQWELLQLEMETLAREHKSGVLK
VIITRGSGGRGYSPGSCHSPGRILSVSAYPEHYSRWRQKGITLTLSPVRLGRNPLLAGIKHLNRLEQVLIRTHLDQTTAD
EALVLDSEGWVTECCAANLFWRQGNVVYTPSLEYAGVKGIMRQFCIHLLAQSSYRVVEVQARPEEVMAADEILLCNALMP
VIPVRTCGDKLLSSRQLFEFLAPLCEHPNSL
>Mature_271_residues
MFLINGQKQTWLAASDRATQFGDGCFTTARIQDGHVIMLTEHIRRLQDACIKLMITFEQWELLQLEMETLAREHKSGVLK
VIITRGSGGRGYSPGSCHSPGRILSVSAYPEHYSRWRQKGITLTLSPVRLGRNPLLAGIKHLNRLEQVLIRTHLDQTTAD
EALVLDSEGWVTECCAANLFWRQGNVVYTPSLEYAGVKGIMRQFCIHLLAQSSYRVVEVQARPEEVMAADEILLCNALMP
VIPVRTCGDKLLSSRQLFEFLAPLCEHPNSL

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=269, Percent_Identity=72.1189591078067, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI48994963, Length=258, Percent_Identity=23.2558139534884, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 30474; Mature: 30474

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLINGQKQTWLAASDRATQFGDGCFTTARIQDGHVIMLTEHIRRLQDACIKLMITFEQW
CEEECCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHH
ELLQLEMETLAREHKSGVLKVIITRGSGGRGYSPGSCHSPGRILSVSAYPEHYSRWRQKG
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHCC
ITLTLSPVRLGRNPLLAGIKHLNRLEQVLIRTHLDQTTADEALVLDSEGWVTECCAANLF
CEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHE
WRQGNVVYTPSLEYAGVKGIMRQFCIHLLAQSSYRVVEVQARPEEVMAADEILLCNALMP
EECCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
VIPVRTCGDKLLSSRQLFEFLAPLCEHPNSL
HHCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFLINGQKQTWLAASDRATQFGDGCFTTARIQDGHVIMLTEHIRRLQDACIKLMITFEQW
CEEECCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHH
ELLQLEMETLAREHKSGVLKVIITRGSGGRGYSPGSCHSPGRILSVSAYPEHYSRWRQKG
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHCC
ITLTLSPVRLGRNPLLAGIKHLNRLEQVLIRTHLDQTTADEALVLDSEGWVTECCAANLF
CEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHE
WRQGNVVYTPSLEYAGVKGIMRQFCIHLLAQSSYRVVEVQARPEEVMAADEILLCNALMP
EECCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
VIPVRTCGDKLLSSRQLFEFLAPLCEHPNSL
HHCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]