Click here to switch to the map view.

The map label for this gene is nikD [H]

Identifier: 218549128

GI number: 218549128

Start: 1831078

End: 1831851

Strand: Reverse

Name: nikD [H]

Synonym: EFER_1780

Alternate gene names: 218549128

Gene position: 1831851-1831078 (Counterclockwise)

Preceding gene: 218549129

Following gene: 218549127

Centisome position: 39.92

GC content: 49.87

Gene sequence:

>774_bases
ATGTTGAGTTTGCAACAAGTGACTCTGGAAGTCGCACGCTATCGTTGGTTTGGTGCCAAACGCTGGTCTCCTTTACTGGA
GGATATTTCTTTTGAGCTCGCGCCAGGGGAGTTGGTGGCGTTAGTGGGTGGCAGTGGGGAAGGGAAAAGCCTGTTATTGC
AGTCACTACTCGATTTGCTGCCAGACAATATCCGCTTAACGGGGAAGATATCCCTTAATGGCTCACCTGTGGATAATCAT
CGTTTGCGACAACTGCGTGGCAAAACATTCAGTTATGTGCCGCAGGGCGTGCAGGCGCTAAATCCGATGTTGGATGTGCA
AAAACATTTGCAACGGGCGTATCAATTAACGGGTAAAAACTGGAATATCCACCATGTGACGCAACTGCTGGCACAAAATC
AACTGGAATCCTCCGTTCTTCGGCGTTATCCACGACAGCTTTCTGGCGGTATGGCGAAACGTGTCCTGGCCTGTCATGCA
GCGTTAAGCGATTGCCGGTATATACTGGCTGATGAAATTACTGCATGGCTGGATGCACCACTGGCGCATCAGCTCATGCA
ACAATTGCAGGACTTGTGCAAACAAGGTTATGGGGTGCTATGGGTGACACACGATTTAATGCTGGCCGGGCAGTATGCTG
ACCGCATTGTCTCGCTTCATCGGGGGCGAGTCAGCGATAACCTTAGTCGGGAACAACTTCTGCAAGGCGAGATGAGCGAA
CAATTAAAGCGTCAGTGGCAGGCATTGCCAGAAAAAAATCTACTTTTTGTCTGA

Upstream 100 bases:

>100_bases
GGTGGCTGGTTTTATTTCCTGGTTTGATGCTCTTTATTCTGGTGATGTTATTTGATCAACTGGCAAGAGCAGTTCAGCAG
TTATGGTTAAGGAACGATAA

Downstream 100 bases:

>100_bases
ATGGGGAAGAAGAATGCTTAGCTGTCGTGATCTGCTCATTCGTCAGGGGGAGAAAGTCCTTTGGCAGAATCTGTCATTTT
CCTTAAGACCGGGCGAGCGG

Product: ATPase of ABC-type transport system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLSLQQVTLEVARYRWFGAKRWSPLLEDISFELAPGELVALVGGSGEGKSLLLQSLLDLLPDNIRLTGKISLNGSPVDNH
RLRQLRGKTFSYVPQGVQALNPMLDVQKHLQRAYQLTGKNWNIHHVTQLLAQNQLESSVLRRYPRQLSGGMAKRVLACHA
ALSDCRYILADEITAWLDAPLAHQLMQQLQDLCKQGYGVLWVTHDLMLAGQYADRIVSLHRGRVSDNLSREQLLQGEMSE
QLKRQWQALPEKNLLFV

Sequences:

>Translated_257_residues
MLSLQQVTLEVARYRWFGAKRWSPLLEDISFELAPGELVALVGGSGEGKSLLLQSLLDLLPDNIRLTGKISLNGSPVDNH
RLRQLRGKTFSYVPQGVQALNPMLDVQKHLQRAYQLTGKNWNIHHVTQLLAQNQLESSVLRRYPRQLSGGMAKRVLACHA
ALSDCRYILADEITAWLDAPLAHQLMQQLQDLCKQGYGVLWVTHDLMLAGQYADRIVSLHRGRVSDNLSREQLLQGEMSE
QLKRQWQALPEKNLLFV
>Mature_257_residues
MLSLQQVTLEVARYRWFGAKRWSPLLEDISFELAPGELVALVGGSGEGKSLLLQSLLDLLPDNIRLTGKISLNGSPVDNH
RLRQLRGKTFSYVPQGVQALNPMLDVQKHLQRAYQLTGKNWNIHHVTQLLAQNQLESSVLRRYPRQLSGGMAKRVLACHA
ALSDCRYILADEITAWLDAPLAHQLMQQLQDLCKQGYGVLWVTHDLMLAGQYADRIVSLHRGRVSDNLSREQLLQGEMSE
QLKRQWQALPEKNLLFV

Specific function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system [H]

COG id: COG1123

COG function: function code R; ATPase components of various ABC-type transport systems, contain duplicated ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1789890, Length=226, Percent_Identity=31.858407079646, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI48994883, Length=211, Percent_Identity=29.3838862559242, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787759, Length=216, Percent_Identity=32.8703703703704, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI145693107, Length=243, Percent_Identity=27.5720164609054, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787029, Length=235, Percent_Identity=27.6595744680851, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788506, Length=215, Percent_Identity=31.1627906976744, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787105, Length=207, Percent_Identity=32.3671497584541, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789963, Length=238, Percent_Identity=27.7310924369748, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788225, Length=217, Percent_Identity=29.9539170506912, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=29.6803652968037, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790467, Length=215, Percent_Identity=31.6279069767442, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789672, Length=254, Percent_Identity=24.0157480314961, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87081834, Length=222, Percent_Identity=31.0810810810811, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789962, Length=228, Percent_Identity=25.4385964912281, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787548, Length=251, Percent_Identity=25.4980079681275, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788761, Length=219, Percent_Identity=30.5936073059361, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786872, Length=249, Percent_Identity=26.9076305220884, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786563, Length=243, Percent_Identity=31.6872427983539, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789991, Length=235, Percent_Identity=23.4042553191489, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788450, Length=215, Percent_Identity=28.3720930232558, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789032, Length=229, Percent_Identity=26.2008733624454, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787089, Length=254, Percent_Identity=29.5275590551181, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790739, Length=217, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787712, Length=218, Percent_Identity=28.8990825688073, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787370, Length=224, Percent_Identity=28.125, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787500, Length=249, Percent_Identity=21.6867469879518, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788644, Length=169, Percent_Identity=26.6272189349112, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787792, Length=223, Percent_Identity=26.9058295964126, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082267, Length=232, Percent_Identity=29.3103448275862, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786703, Length=208, Percent_Identity=32.2115384615385, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1790544, Length=255, Percent_Identity=27.0588235294118, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1787547, Length=243, Percent_Identity=24.6913580246914, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=230, Percent_Identity=29.5652173913043, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17569143, Length=219, Percent_Identity=26.027397260274, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115532730, Length=169, Percent_Identity=28.4023668639053, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI45552805, Length=181, Percent_Identity=30.3867403314917, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17647219, Length=181, Percent_Identity=30.3867403314917, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015857
- InterPro:   IPR003593
- InterPro:   IPR014138 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.24 [H]

Molecular weight: Translated: 29122; Mature: 29122

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLQQVTLEVARYRWFGAKRWSPLLEDISFELAPGELVALVGGSGEGKSLLLQSLLDLL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHC
PDNIRLTGKISLNGSPVDNHRLRQLRGKTFSYVPQGVQALNPMLDVQKHLQRAYQLTGKN
CCCEEEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WNIHHVTQLLAQNQLESSVLRRYPRQLSGGMAKRVLACHAALSDCRYILADEITAWLDAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LAHQLMQQLQDLCKQGYGVLWVTHDLMLAGQYADRIVSLHRGRVSDNLSREQLLQGEMSE
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
QLKRQWQALPEKNLLFV
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLSLQQVTLEVARYRWFGAKRWSPLLEDISFELAPGELVALVGGSGEGKSLLLQSLLDLL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHC
PDNIRLTGKISLNGSPVDNHRLRQLRGKTFSYVPQGVQALNPMLDVQKHLQRAYQLTGKN
CCCEEEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WNIHHVTQLLAQNQLESSVLRRYPRQLSGGMAKRVLACHAALSDCRYILADEITAWLDAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LAHQLMQQLQDLCKQGYGVLWVTHDLMLAGQYADRIVSLHRGRVSDNLSREQLLQGEMSE
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
QLKRQWQALPEKNLLFV
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]