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The map label for this gene is tonB [H]

Identifier: 218549055

GI number: 218549055

Start: 1749482

End: 1750309

Strand: Reverse

Name: tonB [H]

Synonym: EFER_1702

Alternate gene names: 218549055

Gene position: 1750309-1749482 (Counterclockwise)

Preceding gene: 218549059

Following gene: 218549050

Centisome position: 38.14

GC content: 49.28

Gene sequence:

>828_bases
ATGCCATTTCATCGTGCTCAGCTCTGTTGCCTTATTGAATATGATTGCTATTTGCATTTAAAATCAGGGCCTGGTTTTTT
AACTGAAACGATTATGACTTCAATGACGCTTGATTTACCTCGTCGCTTTCCCTGGCCAGCGTTACTTTCGGTCTGCATTC
ACGGTGCACTTGTGGCGGGAATTCTTTATACCTCGGTACATCAGGTTATTGAGCTACCTGCGCCTGCGCAGCCTATTTCA
GTAACAATGGTTGCACCAGCCGATCTGGAGCCGCCGCAGGCTGTACAACCGCCACCGCAACCCGTGGTTGAGCCGGAACC
TGAACCGGAGCCAGAACCCATTCCTGAACCGCCAAAAGAAGCACCAGTGGTGATTGAGAAACCTAAACCGAAGCCTAAGC
CAAAACCAAAGCCAGTGAAAAAGGTGCAGGAACAACCAAAGCGAGATGTACCACCAGCAGAACCTCGTGCGGCATCACCT
TTTGATAATAACGCCGCTGCACGTCCGACTAGCAGTACTGCTACGGCAGCAAATGCCAGACCAGTGGCGAGTGTTGCGTC
TGGACCTCGTGCGCTAAGTCGTAACTCGCCGCAGTATCCGAGACGAGCTCAGGCATTACGACTTGAAGGGCAGGTTAAAG
TAAAGTTTGACGTAACGCCTGATGGTAGAGTAGATAATGTACAGATCCTCTCGGCCAAACCGGCAAATATGTTTGAAAAA
GATGTAAAAACTGCAATGCGCAAATGGCGTTACGAACCCGGCAAACCGGGAAGTGGAATTGTGGTTAATATTTTGTTCCG
GATGAATGGAGCAACCCAAATCCAATAA

Upstream 100 bases:

>100_bases
AAAGTTGTGAAGTACGTTATTTGAAACATCTCACAACTGCAACGCAAAGATAGTGGATTTGTTACAACCATACCTTTAGA
AAGGTTATTTTCGGATAAAA

Downstream 100 bases:

>100_bases
TCAGCCATAAAAAACAAAAGCCTCCGGACAGGAGGCTTTTGCTATTACGGTACGGGCAGTGGTCGAGGTTTTCCATCGGG
ATCCACTGCAACATATTTAA

Product: transport protein TonB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MPFHRAQLCCLIEYDCYLHLKSGPGFLTETIMTSMTLDLPRRFPWPALLSVCIHGALVAGILYTSVHQVIELPAPAQPIS
VTMVAPADLEPPQAVQPPPQPVVEPEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVPPAEPRAASP
FDNNAAARPTSSTATAANARPVASVASGPRALSRNSPQYPRRAQALRLEGQVKVKFDVTPDGRVDNVQILSAKPANMFEK
DVKTAMRKWRYEPGKPGSGIVVNILFRMNGATQIQ

Sequences:

>Translated_275_residues
MPFHRAQLCCLIEYDCYLHLKSGPGFLTETIMTSMTLDLPRRFPWPALLSVCIHGALVAGILYTSVHQVIELPAPAQPIS
VTMVAPADLEPPQAVQPPPQPVVEPEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVPPAEPRAASP
FDNNAAARPTSSTATAANARPVASVASGPRALSRNSPQYPRRAQALRLEGQVKVKFDVTPDGRVDNVQILSAKPANMFEK
DVKTAMRKWRYEPGKPGSGIVVNILFRMNGATQIQ
>Mature_274_residues
PFHRAQLCCLIEYDCYLHLKSGPGFLTETIMTSMTLDLPRRFPWPALLSVCIHGALVAGILYTSVHQVIELPAPAQPISV
TMVAPADLEPPQAVQPPPQPVVEPEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVPPAEPRAASPF
DNNAAARPTSSTATAANARPVASVASGPRALSRNSPQYPRRAQALRLEGQVKVKFDVTPDGRVDNVQILSAKPANMFEKD
VKTAMRKWRYEPGKPGSGIVVNILFRMNGATQIQ

Specific function: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates such as cobalamin, and various iron compounds (such as iron dicitrate, enterochelin, aerobac

COG id: COG0810

COG function: function code M; Periplasmic protein TonB, links inner and outer membranes

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB family [H]

Homologues:

Organism=Escherichia coli, GI1787505, Length=241, Percent_Identity=86.3070539419087, Blast_Score=313, Evalue=6e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003538
- InterPro:   IPR006260 [H]

Pfam domain/function: PF03544 TonB [H]

EC number: NA

Molecular weight: Translated: 30028; Mature: 29897

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFHRAQLCCLIEYDCYLHLKSGPGFLTETIMTSMTLDLPRRFPWPALLSVCIHGALVAG
CCCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ILYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPQPVVEPEPEPEPEPIPEPPKE
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APVVIEKPKPKPKPKPKPVKKVQEQPKRDVPPAEPRAASPFDNNAAARPTSSTATAANAR
CCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVASVASGPRALSRNSPQYPRRAQALRLEGQVKVKFDVTPDGRVDNVQILSAKPANMFEK
CHHHHHCCCHHHCCCCCCCCCHHHHEEECCEEEEEEECCCCCCCCCEEEEECCCHHHHHH
DVKTAMRKWRYEPGKPGSGIVVNILFRMNGATQIQ
HHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure 
PFHRAQLCCLIEYDCYLHLKSGPGFLTETIMTSMTLDLPRRFPWPALLSVCIHGALVAG
CCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ILYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPQPVVEPEPEPEPEPIPEPPKE
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APVVIEKPKPKPKPKPKPVKKVQEQPKRDVPPAEPRAASPFDNNAAARPTSSTATAANAR
CCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVASVASGPRALSRNSPQYPRRAQALRLEGQVKVKFDVTPDGRVDNVQILSAKPANMFEK
CHHHHHCCCHHHCCCCCCCCCHHHHEEECCEEEEEEECCCCCCCCCEEEEECCCHHHHHH
DVKTAMRKWRYEPGKPGSGIVVNILFRMNGATQIQ
HHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6310567; 9097039; 9278503; 1885532; 8316087; 11328822 [H]