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The map label for this gene is pcaI [H]

Identifier: 218548988

GI number: 218548988

Start: 1682602

End: 1683324

Strand: Reverse

Name: pcaI [H]

Synonym: EFER_1636

Alternate gene names: 218548988

Gene position: 1683324-1682602 (Counterclockwise)

Preceding gene: 218548990

Following gene: 218548987

Centisome position: 36.68

GC content: 50.9

Gene sequence:

>723_bases
ATGTGCGAAATCCGCACGACAAGGAGCAACCTGATGATTGATAAACGTGTGTCATCGCTCGAAGAGGCCATCGCCGGGAT
TGCGGATGGCGACACCATAATGATTGGTGGATTTGGCACCGCCGGACAACCCACGTATCTGATCGATGCCCTGATCGATC
AAGGGGCACGCGATCTCACCATTATTAACAACAATGCCGGCAACGGTGAAGTAGGACTGGCGGCGCTACTTAAAGCAAAA
CGAGTAAGGAAAATGATTTGCTCGTTTCCCCGTCAGGTGGACTCGCAAATTTTTGACGCCTTATACCGCAATAAAGAAAT
AGAGCTTGAACTTGTGCCACAGGGTAACCTGGCGGCACGTATCCAGGCTGCGGGGGCAGGGCTGGGCGCGATTTTTACCC
CAACAGGTTACGGTACTACGCTTGCAGAAGGTAAAGAAACACGCCACATCGACGGACGTGACTATGTACTGGAATACCCT
ATCAAAGCTGACTTTGCCCTGATCAAAGCGCATCAGGCTGACCGTTGGGGAAATCTGGTATATCGCAAAGCTGCACGTAA
TTTTGGTCCGATTATGGCCACTGCGGCGAAAACCACCGTTGTGGAAGTCAGCCAGTTTGTTGAGCTGGGAGAACTGGATC
CAGAACATATCATTACGCCAGGCATCTTCGTCCAACGCGTTTTTTCCCTTGAAAATCTGCAAGATAACGCACTGAGCGCC
TAA

Upstream 100 bases:

>100_bases
CTAACAAATATATCTGATGTTCGATAATCGCACCATATTTCGATTATCGCCCTTGATTGCATTCGTTATGTGGGTCACAT
TTTGTGCGAACAACGTATAA

Downstream 100 bases:

>100_bases
GGAGTCAATAATGAAAAAGCTTTCGCGTGATGAAATGGCGAAACGCGTTGCCCAGGATATCCCGGAAGGCGCATACGTCA
ATCTTGGGATTGGTCTGCCG

Product: 3-oxoadipate CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MCEIRTTRSNLMIDKRVSSLEEAIAGIADGDTIMIGGFGTAGQPTYLIDALIDQGARDLTIINNNAGNGEVGLAALLKAK
RVRKMICSFPRQVDSQIFDALYRNKEIELELVPQGNLAARIQAAGAGLGAIFTPTGYGTTLAEGKETRHIDGRDYVLEYP
IKADFALIKAHQADRWGNLVYRKAARNFGPIMATAAKTTVVEVSQFVELGELDPEHIITPGIFVQRVFSLENLQDNALSA

Sequences:

>Translated_240_residues
MCEIRTTRSNLMIDKRVSSLEEAIAGIADGDTIMIGGFGTAGQPTYLIDALIDQGARDLTIINNNAGNGEVGLAALLKAK
RVRKMICSFPRQVDSQIFDALYRNKEIELELVPQGNLAARIQAAGAGLGAIFTPTGYGTTLAEGKETRHIDGRDYVLEYP
IKADFALIKAHQADRWGNLVYRKAARNFGPIMATAAKTTVVEVSQFVELGELDPEHIITPGIFVQRVFSLENLQDNALSA
>Mature_240_residues
MCEIRTTRSNLMIDKRVSSLEEAIAGIADGDTIMIGGFGTAGQPTYLIDALIDQGARDLTIINNNAGNGEVGLAALLKAK
RVRKMICSFPRQVDSQIFDALYRNKEIELELVPQGNLAARIQAAGAGLGAIFTPTGYGTTLAEGKETRHIDGRDYVLEYP
IKADFALIKAHQADRWGNLVYRKAARNFGPIMATAAKTTVVEVSQFVELGELDPEHIITPGIFVQRVFSLENLQDNALSA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=231, Percent_Identity=43.2900432900433, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI11545841, Length=224, Percent_Identity=43.75, Blast_Score=172, Evalue=3e-43,
Organism=Escherichia coli, GI1788551, Length=220, Percent_Identity=42.7272727272727, Blast_Score=184, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17531517, Length=248, Percent_Identity=40.3225806451613, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21358325, Length=229, Percent_Identity=41.0480349344978, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24655794, Length=229, Percent_Identity=41.0480349344978, Blast_Score=174, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 26065; Mature: 26065

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCEIRTTRSNLMIDKRVSSLEEAIAGIADGDTIMIGGFGTAGQPTYLIDALIDQGARDLT
CCCEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEE
IINNNAGNGEVGLAALLKAKRVRKMICSFPRQVDSQIFDALYRNKEIELELVPQGNLAAR
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEE
IQAAGAGLGAIFTPTGYGTTLAEGKETRHIDGRDYVLEYPIKADFALIKAHQADRWGNLV
EEECCCCCCEEECCCCCCCCHHCCCCCCCCCCCCEEEECCCCCCEEEEEHHCCCHHHHHH
YRKAARNFGPIMATAAKTTVVEVSQFVELGELDPEHIITPGIFVQRVFSLENLQDNALSA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MCEIRTTRSNLMIDKRVSSLEEAIAGIADGDTIMIGGFGTAGQPTYLIDALIDQGARDLT
CCCEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEE
IINNNAGNGEVGLAALLKAKRVRKMICSFPRQVDSQIFDALYRNKEIELELVPQGNLAAR
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEE
IQAAGAGLGAIFTPTGYGTTLAEGKETRHIDGRDYVLEYPIKADFALIKAHQADRWGNLV
EEECCCCCCEEECCCCCCCCHHCCCCCCCCCCCCEEEECCCCCCEEEEEHHCCCHHHHHH
YRKAARNFGPIMATAAKTTVVEVSQFVELGELDPEHIITPGIFVQRVFSLENLQDNALSA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]