BacMap

Definition	Escherichia fergusonii ATCC 35469 chromosome, complete genome.
Accession	NC_011740
Length	4,588,711

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The map label for this gene is ydfG [H]

Identifier: 218548891

GI number: 218548891

Start: 1569555

End: 1570301

Strand: Reverse

Name: ydfG [H]

Synonym: EFER_1536

Alternate gene names: 218548891

Gene position: 1570301-1569555 (Counterclockwise)

Preceding gene: 218548893

Following gene: 218548890

Centisome position: 34.22

GC content: 48.06

Gene sequence:

>747_bases
ATGATCGTTTTAGTTACCGGGGCTACTGCAGGTTTTGGGGAAAGCATCACGCGTCGTTTTATCCAGAACGGCCATAAAGT
TATAGCGACCGGGCGTCGCCAGGAGCGACTTCAGGAGTTGAAAGATGAATTAGGCGCAAACTTATTCATCGCCCAGCTCG
ATGTACGTAATCGGGCAGCCATTGAAGAGATGCTTGAATCGTTACCGCCTGAGTTTCGCGACATTGATATTTTAGTTAAT
AACGCCGGTCTGGCACTGGGGCTGGAACCTGCCCATAAAGCCAATGTTGAAGACTGGGAAACGATGATCGATACCAACAA
TAAAGGGCTGATTTATATGACTCGCGCTGTACTGCCAGGCATGGTTGAGCGCAATCGGGGGCATATTATTAATATCGGTT
CCACGGCAGGTAGCTGGCCCTATGCTGGTGGCAACGTCTATGGCGCCACAAAAGCGTTTGTCCGTCAGTTCAGTCTGAAT
TTACGTACAGATTTACATGGTACAGCGGTACGTGTAACAGATATTGAACCCGGTTTAGTCGGCGGCACTGAATTTTCTAA
CGTCCGCTTTAAAGGCGACGATGATAAAGCCGGTAAAACTTACGAAAATACCGTTGCGCTGACGCCAGAAGATATAACTG
AAGCGGTCTGGTGGGTTTCAACTCTACCCGCGCATGTCAATGTGAATACCCTTGAAATTATGCCCGTTACCCAAACTTAT
GCGGGTCTAAACATTCATCGCCAGTAA

Upstream 100 bases:

>100_bases
GCATTGGCGGTTACAGGCGCAATGTTGTAATCCTTATTACCCGCCCTCAGTTAACGCGTGCTATGTTATTAGCTTCCGAA
AAGTGCTGAGGAACAGTGAA

Downstream 100 bases:

>100_bases
TTTTATACCCGGCTTAATCGCCGGGTTATAGCTTAAGGCAAAAAAGTGGTAAACTTGTAAGGTTTACTCACTGAAAAGCC
AGAACAATGACCGTCGAAAC

Product: 3-hydroxy acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MIVLVTGATAGFGESITRRFIQNGHKVIATGRRQERLQELKDELGANLFIAQLDVRNRAAIEEMLESLPPEFRDIDILVN
NAGLALGLEPAHKANVEDWETMIDTNNKGLIYMTRAVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDDKAGKTYENTVALTPEDITEAVWWVSTLPAHVNVNTLEIMPVTQTY
AGLNIHRQ

Sequences:

>Translated_248_residues
MIVLVTGATAGFGESITRRFIQNGHKVIATGRRQERLQELKDELGANLFIAQLDVRNRAAIEEMLESLPPEFRDIDILVN
NAGLALGLEPAHKANVEDWETMIDTNNKGLIYMTRAVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDDKAGKTYENTVALTPEDITEAVWWVSTLPAHVNVNTLEIMPVTQTY
AGLNIHRQ
>Mature_248_residues
MIVLVTGATAGFGESITRRFIQNGHKVIATGRRQERLQELKDELGANLFIAQLDVRNRAAIEEMLESLPPEFRDIDILVN
NAGLALGLEPAHKANVEDWETMIDTNNKGLIYMTRAVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDDKAGKTYENTVALTPEDITEAVWWVSTLPAHVNVNTLEIMPVTQTY
AGLNIHRQ

Specific function: Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine [H]

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=33.8709677419355, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI7705855, Length=204, Percent_Identity=30.3921568627451, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=30.0518134715026, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI7657478, Length=263, Percent_Identity=29.6577946768061, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI19923817, Length=188, Percent_Identity=29.2553191489362, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI150247226, Length=190, Percent_Identity=31.5789473684211, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=31.0526315789474, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI22507405, Length=178, Percent_Identity=32.0224719101124, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI157739938, Length=187, Percent_Identity=26.7379679144385, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI40548397, Length=179, Percent_Identity=31.8435754189944, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI214010158, Length=179, Percent_Identity=31.8435754189944, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI214010156, Length=179, Percent_Identity=31.8435754189944, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI22758144, Length=179, Percent_Identity=31.8435754189944, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4557649, Length=179, Percent_Identity=30.1675977653631, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19743808, Length=178, Percent_Identity=29.7752808988764, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI32483357, Length=227, Percent_Identity=26.431718061674, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI119392083, Length=190, Percent_Identity=28.4210526315789, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40254992, Length=180, Percent_Identity=25.5555555555556, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=29.6296296296296, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4504503, Length=217, Percent_Identity=24.8847926267281, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI44680136, Length=184, Percent_Identity=29.3478260869565, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI44680133, Length=184, Percent_Identity=29.3478260869565, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI17738292, Length=184, Percent_Identity=29.3478260869565, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=192, Percent_Identity=26.0416666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31542939, Length=190, Percent_Identity=31.0526315789474, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503817, Length=183, Percent_Identity=25.6830601092896, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI50726952, Length=180, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031737, Length=197, Percent_Identity=26.3959390862944, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI66933014, Length=167, Percent_Identity=29.940119760479, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI7705925, Length=179, Percent_Identity=28.4916201117318, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787820, Length=248, Percent_Identity=91.1290322580645, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1787335, Length=197, Percent_Identity=35.0253807106599, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI87082100, Length=181, Percent_Identity=33.7016574585635, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786812, Length=179, Percent_Identity=29.0502793296089, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790717, Length=179, Percent_Identity=26.8156424581006, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787526, Length=224, Percent_Identity=25, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=204, Percent_Identity=30.8823529411765, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=245, Percent_Identity=28.1632653061224, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=236, Percent_Identity=26.6949152542373, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=241, Percent_Identity=28.2157676348548, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=247, Percent_Identity=28.3400809716599, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=235, Percent_Identity=25.531914893617, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=190, Percent_Identity=27.8947368421053, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=213, Percent_Identity=30.9859154929577, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=226, Percent_Identity=27.8761061946903, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=223, Percent_Identity=30.0448430493274, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=188, Percent_Identity=30.3191489361702, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=25.8196721311475, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=187, Percent_Identity=28.8770053475936, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25152911, Length=221, Percent_Identity=29.8642533936652, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=191, Percent_Identity=28.7958115183246, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560176, Length=215, Percent_Identity=29.3023255813954, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=212, Percent_Identity=27.3584905660377, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=189, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559552, Length=222, Percent_Identity=27.9279279279279, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=250, Percent_Identity=27.2, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17557668, Length=215, Percent_Identity=29.3023255813954, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=29.2929292929293, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=29.2929292929293, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=191, Percent_Identity=28.7958115183246, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI212646214, Length=222, Percent_Identity=27.4774774774775, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=194, Percent_Identity=27.319587628866, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=181, Percent_Identity=26.5193370165746, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=187, Percent_Identity=27.807486631016, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=156, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=154, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=179, Percent_Identity=30.1675977653631, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=244, Percent_Identity=39.344262295082, Blast_Score=168, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=27.0408163265306, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=30.1136363636364, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=193, Percent_Identity=24.8704663212435, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI116007236, Length=253, Percent_Identity=31.6205533596838, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281364494, Length=253, Percent_Identity=29.6442687747036, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21358495, Length=223, Percent_Identity=29.5964125560538, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI23397609, Length=180, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641388, Length=251, Percent_Identity=29.4820717131474, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24643142, Length=179, Percent_Identity=32.4022346368715, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24641232, Length=254, Percent_Identity=27.9527559055118, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=29.8969072164948, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=31.7204301075269, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24663911, Length=252, Percent_Identity=26.984126984127, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571526, Length=233, Percent_Identity=27.4678111587983, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24648693, Length=253, Percent_Identity=28.4584980237154, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21355889, Length=253, Percent_Identity=28.4584980237154, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI28571387, Length=252, Percent_Identity=27.3809523809524, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI116007234, Length=253, Percent_Identity=28.0632411067194, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357041, Length=183, Percent_Identity=26.775956284153, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24584748, Length=181, Percent_Identity=28.1767955801105, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161076933, Length=181, Percent_Identity=28.1767955801105, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17737361, Length=191, Percent_Identity=29.8429319371728, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574402, Length=186, Percent_Identity=30.1075268817204, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584744, Length=186, Percent_Identity=30.1075268817204, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644339, Length=205, Percent_Identity=24.8780487804878, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580925, Length=224, Percent_Identity=26.3392857142857, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648944, Length=240, Percent_Identity=25.8333333333333, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584752, Length=182, Percent_Identity=28.021978021978, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331216, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355631, Length=180, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24665247, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639444, Length=190, Percent_Identity=30.5263157894737, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27311; Mature: 27311

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLVTGATAGFGESITRRFIQNGHKVIATGRRQERLQELKDELGANLFIAQLDVRNRAA
CEEEEECCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCEEEEEEECCCCHHH
IEEMLESLPPEFRDIDILVNNAGLALGLEPAHKANVEDWETMIDTNNKGLIYMTRAVLPG
HHHHHHHCCCCCCEEEEEEECCCEEEECCCCCCCCCHHHHHHHCCCCCCEEEEHHHHCCH
MVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDIEPGLV
HHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECCCCCC
GGTEFSNVRFKGDDDKAGKTYENTVALTPEDITEAVWWVSTLPAHVNVNTLEIMPVTQTY
CCCCCCCEEEECCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCEECCEEEEEEEECHHH
AGLNIHRQ
CCCEEECC
>Mature Secondary Structure
MIVLVTGATAGFGESITRRFIQNGHKVIATGRRQERLQELKDELGANLFIAQLDVRNRAA
CEEEEECCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCEEEEEEECCCCHHH
IEEMLESLPPEFRDIDILVNNAGLALGLEPAHKANVEDWETMIDTNNKGLIYMTRAVLPG
HHHHHHHCCCCCCEEEEEEECCCEEEECCCCCCCCCHHHHHHHCCCCCCEEEEHHHHCCH
MVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDIEPGLV
HHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECCCCCC
GGTEFSNVRFKGDDDKAGKTYENTVALTPEDITEAVWWVSTLPAHVNVNTLEIMPVTQTY
CCCCCCCEEEECCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCEECCEEEEEEEECHHH
AGLNIHRQ
CCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]