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The map label for this gene is tehB [H]

Identifier: 218548863

GI number: 218548863

Start: 1543310

End: 1543906

Strand: Direct

Name: tehB [H]

Synonym: EFER_1508

Alternate gene names: 218548863

Gene position: 1543310-1543906 (Clockwise)

Preceding gene: 218548861

Following gene: 218548864

Centisome position: 33.63

GC content: 47.4

Gene sequence:

>597_bases
ATGATCGTTCGTGACGAAAATTACTTCACTGAAAAATATGAATTAACCCGTACACATTCAGAAGTGCTCGATGCTGTTAA
AGTGGTTAAACCGGGTAAAACATTGGATCTGGGATGCGGTAATGGTCGGAACAGCCTTTATCTGGCAGCCAATGGGTTTG
ATGTGGATGCCTGGGATAAAAATGCCATGAGCATCGCTAACGTCGAGCGAATTAAGGCTCTTGAAGGGCTGGAGAATCTG
CACACCCGGATTGTGGATCTCAATACTCTCAGATTCGAAGGGCAGTATGATTTCATTCTTTCCACCGTGGTGTTGATGTT
CCTAGAGGCGAAGACGATCCCTGGTTTAATCGCCAATATGCAGCACTGTACCAGACCGGGCGGTTACAACTTGATTGTGG
CGGCTATGGATACTGATGATTTCCCTTGTACAGTTGGTTTTCCGTTTGCCTTTAAAGAAGGGGAGTTACGGGACTATTAC
GCTGGCTGGGAGCCGCTGAAGTACAACGAAGATGTGGGGGAACTGCACCGTACCGACGAAAATGGCAACCGTATTAAATT
GCGTTTTGCCACCATGCTGGCGCGTAAAACCGTCTGA

Upstream 100 bases:

>100_bases
TGTTTCCGACCGCGTTGCCATCCATACCTTCGTACATCTGATACAACGGAAATTGTTAACCAGAATGAGCGCGCCGTATT
AATGAAATCCGAGGAAAAAC

Downstream 100 bases:

>100_bases
TATTCTGCCAATTGTTAACTGCTCTGCGTCCCCCCGACGCAGAGAAATATATGTGAACCTGTTACCATTTTTAGTGCGAC
AGAAATGATTTCACTTTGCT

Product: tellurite resistance protein TehB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MIVRDENYFTEKYELTRTHSEVLDAVKVVKPGKTLDLGCGNGRNSLYLAANGFDVDAWDKNAMSIANVERIKALEGLENL
HTRIVDLNTLRFEGQYDFILSTVVLMFLEAKTIPGLIANMQHCTRPGGYNLIVAAMDTDDFPCTVGFPFAFKEGELRDYY
AGWEPLKYNEDVGELHRTDENGNRIKLRFATMLARKTV

Sequences:

>Translated_198_residues
MIVRDENYFTEKYELTRTHSEVLDAVKVVKPGKTLDLGCGNGRNSLYLAANGFDVDAWDKNAMSIANVERIKALEGLENL
HTRIVDLNTLRFEGQYDFILSTVVLMFLEAKTIPGLIANMQHCTRPGGYNLIVAAMDTDDFPCTVGFPFAFKEGELRDYY
AGWEPLKYNEDVGELHRTDENGNRIKLRFATMLARKTV
>Mature_198_residues
MIVRDENYFTEKYELTRTHSEVLDAVKVVKPGKTLDLGCGNGRNSLYLAANGFDVDAWDKNAMSIANVERIKALEGLENL
HTRIVDLNTLRFEGQYDFILSTVVLMFLEAKTIPGLIANMQHCTRPGGYNLIVAAMDTDDFPCTVGFPFAFKEGELRDYY
AGWEPLKYNEDVGELHRTDENGNRIKLRFATMLARKTV

Specific function: Probable S-adenosyl-L-methionine dependent methyltransferase that is responsible for tellurite resistance when present in high copy number. Binds tellurite and S-adenosyl- L-methionine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable). Note=Probably a peripheral membrane protein that interacts with TehA [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TehB family [H]

Homologues:

Organism=Escherichia coli, GI1787700, Length=196, Percent_Identity=88.7755102040816, Blast_Score=369, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004537
- InterPro:   IPR015985 [H]

Pfam domain/function: PF03848 TehB [H]

EC number: NA

Molecular weight: Translated: 22436; Mature: 22436

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRDENYFTEKYELTRTHSEVLDAVKVVKPGKTLDLGCGNGRNSLYLAANGFDVDAWDK
CEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCCC
NAMSIANVERIKALEGLENLHTRIVDLNTLRFEGQYDFILSTVVLMFLEAKTIPGLIANM
CCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHH
QHCTRPGGYNLIVAAMDTDDFPCTVGFPFAFKEGELRDYYAGWEPLKYNEDVGELHRTDE
HHHCCCCCCEEEEEEECCCCCCEEECCCEEECCCCCHHHHCCCCCCCCCCCHHHHHCCCC
NGNRIKLRFATMLARKTV
CCCEEEEEHHHHHHHCCC
>Mature Secondary Structure
MIVRDENYFTEKYELTRTHSEVLDAVKVVKPGKTLDLGCGNGRNSLYLAANGFDVDAWDK
CEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCCC
NAMSIANVERIKALEGLENLHTRIVDLNTLRFEGQYDFILSTVVLMFLEAKTIPGLIANM
CCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHH
QHCTRPGGYNLIVAAMDTDDFPCTVGFPFAFKEGELRDYYAGWEPLKYNEDVGELHRTDE
HHHCCCCCCEEEEEEECCCCCCEEECCCEEECCCCCHHHHCCCCCCCCCCCHHHHHCCCC
NGNRIKLRFATMLARKTV
CCCEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2060788; 9097039; 9278503; 8169225 [H]