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The map label for this gene is idnR [H]

Identifier: 218548831

GI number: 218548831

Start: 1511964

End: 1513007

Strand: Direct

Name: idnR [H]

Synonym: EFER_1474

Alternate gene names: 218548831

Gene position: 1511964-1513007 (Clockwise)

Preceding gene: 218548828

Following gene: 218548832

Centisome position: 32.95

GC content: 48.95

Gene sequence:

>1044_bases
ATGCAGAATAAAATTCAAAATAAATCAGAGGCTTCTGTTGTGAAAATACCAAAATCGCCACGAGCGCCGACGCTGGATGA
TGTTGCCCGTAATGCAGGATTATCGTCAATGACGGTGAGTCGGGCACTGAACACACCACAACTGGTGCGCCCGGCAACAC
TGGAAAAAGTTATGCAAGCGGTACGCGCAACCGGGTATATCCCCAATGCGCTGGCGGGAGGGCTGGCGTCACGGCGCAGT
AAACTTATTGCCGTAGTAGTACCGCAAATCAACAACAGTATGTTTGTTGATACAATCCAGGCGTTAAGTGATGAGTTGGC
GATTCGTGGCTATCATATTTTGCTCTGCGTGACAGGTTATAGCGAAGAAACAGAAGCCGAACTGGTTGCGACACTGCTTT
CCCGCCGTCCTGACGGGGTAGTATTAACGGGCATTCACCATACTCATGAACTGAAAAAAATCATCCTGAATGCAGCAATT
CCGGTGATAGAAATCTGGGATTTAACGCCAACGCCACTTGATATGTTAGTTGGTTTCTCTCATGAAAAAGTGGGGCAGGC
GACAGGCGAATATTTAATTAAAAAAGGTTATCGTCGCCCTGGTTTGTTATGGACTGATGATCGCCGGGCGGCTCAGCGTA
AACAGGGTCTGTGTGACATATTTTTTCGTCATGGTGTTACTCACCTGGCGCAAGTCAATGTTCCGCTGCCTGCGTCGTTG
TCGCTCGGACGTAGTGGTCTTGCTGAGCTATTTGCCATGGCTGAATTTGATGTCATTGTCTGCAGCTCTGATACCCTGGC
TCAGGGCGCGATAATGCAAGCCGAAAGTCAGGGTATGCGTGTGCCAAAAGATATCGCAGTAATGGGCTTTGGCGATCTCG
ATTTTGCCGCCAGTAATCGGCCTTCCATTACGACAGTGAGTGTCGACAGAAGCGGGATGGGGCAACGAGCCGCTGCACTG
CTTGCTGATCGTATAGAAAACATTGAACGCGACGCATCAATTATTGATCTTGGTTTTCATCTTATTGAGCGCGACTCCGC
ATAA

Upstream 100 bases:

>100_bases
AAATGCACAATTTTTCATGATAGCGATAACATTCATCAACTATCCGCTATGATTATCTGGACAAAGTATCCGTTGGGACT
GGAGTTTAGTTTGAGCAGCA

Downstream 100 bases:

>100_bases
ACAAACAAATGCCAGTCGCAGACTGTGCTAGCTTTGCTAATACTTTCAAAAGGAGCAAAACAATGCCGCATATCGATATC
AAATGTTTTCCGCGTGAACT

Product: lacI family transcriptional regulator

Products: NA

Alternate protein names: L-idonate regulatory protein [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MQNKIQNKSEASVVKIPKSPRAPTLDDVARNAGLSSMTVSRALNTPQLVRPATLEKVMQAVRATGYIPNALAGGLASRRS
KLIAVVVPQINNSMFVDTIQALSDELAIRGYHILLCVTGYSEETEAELVATLLSRRPDGVVLTGIHHTHELKKIILNAAI
PVIEIWDLTPTPLDMLVGFSHEKVGQATGEYLIKKGYRRPGLLWTDDRRAAQRKQGLCDIFFRHGVTHLAQVNVPLPASL
SLGRSGLAELFAMAEFDVIVCSSDTLAQGAIMQAESQGMRVPKDIAVMGFGDLDFAASNRPSITTVSVDRSGMGQRAAAL
LADRIENIERDASIIDLGFHLIERDSA

Sequences:

>Translated_347_residues
MQNKIQNKSEASVVKIPKSPRAPTLDDVARNAGLSSMTVSRALNTPQLVRPATLEKVMQAVRATGYIPNALAGGLASRRS
KLIAVVVPQINNSMFVDTIQALSDELAIRGYHILLCVTGYSEETEAELVATLLSRRPDGVVLTGIHHTHELKKIILNAAI
PVIEIWDLTPTPLDMLVGFSHEKVGQATGEYLIKKGYRRPGLLWTDDRRAAQRKQGLCDIFFRHGVTHLAQVNVPLPASL
SLGRSGLAELFAMAEFDVIVCSSDTLAQGAIMQAESQGMRVPKDIAVMGFGDLDFAASNRPSITTVSVDRSGMGQRAAAL
LADRIENIERDASIIDLGFHLIERDSA
>Mature_347_residues
MQNKIQNKSEASVVKIPKSPRAPTLDDVARNAGLSSMTVSRALNTPQLVRPATLEKVMQAVRATGYIPNALAGGLASRRS
KLIAVVVPQINNSMFVDTIQALSDELAIRGYHILLCVTGYSEETEAELVATLLSRRPDGVVLTGIHHTHELKKIILNAAI
PVIEIWDLTPTPLDMLVGFSHEKVGQATGEYLIKKGYRRPGLLWTDDRRAAQRKQGLCDIFFRHGVTHLAQVNVPLPASL
SLGRSGLAELFAMAEFDVIVCSSDTLAQGAIMQAESQGMRVPKDIAVMGFGDLDFAASNRPSITTVSVDRSGMGQRAAAL
LADRIENIERDASIIDLGFHLIERDSA

Specific function: Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790715, Length=321, Percent_Identity=30.2180685358255, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI48994940, Length=327, Percent_Identity=31.4984709480122, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790369, Length=325, Percent_Identity=27.0769230769231, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790194, Length=341, Percent_Identity=28.4457478005865, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787948, Length=337, Percent_Identity=24.0356083086053, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788474, Length=314, Percent_Identity=27.7070063694268, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=26.1016949152542, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786540, Length=305, Percent_Identity=27.8688524590164, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786268, Length=307, Percent_Identity=24.4299674267101, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787906, Length=255, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37625; Mature: 37625

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNKIQNKSEASVVKIPKSPRAPTLDDVARNAGLSSMTVSRALNTPQLVRPATLEKVMQA
CCCCCCCCCCCCEEECCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCHHCCHHHHHHHHHH
VRATGYIPNALAGGLASRRSKLIAVVVPQINNSMFVDTIQALSDELAIRGYHILLCVTGY
HHHCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECC
SEETEAELVATLLSRRPDGVVLTGIHHTHELKKIILNAAIPVIEIWDLTPTPLDMLVGFS
CCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHCCC
HEKVGQATGEYLIKKGYRRPGLLWTDDRRAAQRKQGLCDIFFRHGVTHLAQVNVPLPASL
HHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCHHHHHHHCCHHHHEEECCCCCCCC
SLGRSGLAELFAMAEFDVIVCSSDTLAQGAIMQAESQGMRVPKDIAVMGFGDLDFAASNR
CCCHHHHHHHHHHHHCCEEEECCCCHHHCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCC
PSITTVSVDRSGMGQRAAALLADRIENIERDASIIDLGFHLIERDSA
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQNKIQNKSEASVVKIPKSPRAPTLDDVARNAGLSSMTVSRALNTPQLVRPATLEKVMQA
CCCCCCCCCCCCEEECCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCHHCCHHHHHHHHHH
VRATGYIPNALAGGLASRRSKLIAVVVPQINNSMFVDTIQALSDELAIRGYHILLCVTGY
HHHCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECC
SEETEAELVATLLSRRPDGVVLTGIHHTHELKKIILNAAIPVIEIWDLTPTPLDMLVGFS
CCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHCCC
HEKVGQATGEYLIKKGYRRPGLLWTDDRRAAQRKQGLCDIFFRHGVTHLAQVNVPLPASL
HHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCHHHHHHHCCHHHHEEECCCCCCCC
SLGRSGLAELFAMAEFDVIVCSSDTLAQGAIMQAESQGMRVPKDIAVMGFGDLDFAASNR
CCCHHHHHHHHHHHHCCEEEECCCCHHHCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCC
PSITTVSVDRSGMGQRAAALLADRIENIERDASIIDLGFHLIERDSA
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]