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The map label for this gene is rstA [H]

Identifier: 218548790

GI number: 218548790

Start: 1469777

End: 1470538

Strand: Reverse

Name: rstA [H]

Synonym: EFER_1429

Alternate gene names: 218548790

Gene position: 1470538-1469777 (Counterclockwise)

Preceding gene: 218548792

Following gene: 218548789

Centisome position: 32.05

GC content: 46.33

Gene sequence:

>762_bases
GTGCCAGTGTATGGTGAGGTTTTTATTTCCACTATGAATATTATGAACACACTCGTTTTTGTCGAAGATGATGCTGAAGT
AGGCTCTCTGATTGCTGCTTATCTGGCAAAACATGATCTTAATGTTATCGTCGAACCGCGTGGTGATAAGGCGGAAGAAG
TCATTGCCAGCATTCAACCAAACCTGGTATTGCTGGATATTATGCTTCCTGGCAAAGACGGGATGAGTATTTGTCGTGAT
TTGCGTGGTAAATATGCCGGCCCTATTGTGCTTCTGACATCACTTGATAGCGACATGAATCATATTCTGGCGCTGGAATT
GGGGGCTTGTGACTATATTCTGAAAACGACACCCCCGGCTGTGTTGCTGGCGCGGTTACGTTTGCACTTGCGACAAAATG
AACTAACGCAACAGAGCAAAGGTATTCAGGACTCTGTGCTGAAAATGCATAGCACGTTGTGCTTTGGTTCTTTGAGTATC
GATCCTATTAATCGCAGTGTACTTCTTGCCGGAGAAGAGGTCGTGCTTTCTACTGCCGATTTCGAACTGCTTTGGGAACT
GGCTACCCATGCCGGGCAAATAATGGACCGCGATGCCCTACTGATGAGTCTGCGCGGTGTCAGTTATGACGGCTTAGATC
GAAGCGTGGATGTCGCTGTTTCTCGTTTACGTAAGAAATTACTCGATAACGCCGCCGAACCTTACCGGATCAAAACTATT
CGTAATAAAGGTTATTTGTTCGCGCCACACGCCTGGGAATAA

Upstream 100 bases:

>100_bases
TACTAAACCCATCCTCATTCACCTTAACACTTTAATAACATATTCTCAGTAGAATACCTTATGCTCTTTTGTTTAGGAAC
GATTGATATGCAGGTAAAAC

Downstream 100 bases:

>100_bases
ACGGGTTAAGATATGAAAAAACTTTTTGTTCAGTTTTATCTGCTTCTCTTCACCTGTTTTCTGGTAATGACCTTGTTAGT
GGGGCTGGTATATAAATTCA

Product: DNA-binding transcriptional regulator RstA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MPVYGEVFISTMNIMNTLVFVEDDAEVGSLIAAYLAKHDLNVIVEPRGDKAEEVIASIQPNLVLLDIMLPGKDGMSICRD
LRGKYAGPIVLLTSLDSDMNHILALELGACDYILKTTPPAVLLARLRLHLRQNELTQQSKGIQDSVLKMHSTLCFGSLSI
DPINRSVLLAGEEVVLSTADFELLWELATHAGQIMDRDALLMSLRGVSYDGLDRSVDVAVSRLRKKLLDNAAEPYRIKTI
RNKGYLFAPHAWE

Sequences:

>Translated_253_residues
MPVYGEVFISTMNIMNTLVFVEDDAEVGSLIAAYLAKHDLNVIVEPRGDKAEEVIASIQPNLVLLDIMLPGKDGMSICRD
LRGKYAGPIVLLTSLDSDMNHILALELGACDYILKTTPPAVLLARLRLHLRQNELTQQSKGIQDSVLKMHSTLCFGSLSI
DPINRSVLLAGEEVVLSTADFELLWELATHAGQIMDRDALLMSLRGVSYDGLDRSVDVAVSRLRKKLLDNAAEPYRIKTI
RNKGYLFAPHAWE
>Mature_252_residues
PVYGEVFISTMNIMNTLVFVEDDAEVGSLIAAYLAKHDLNVIVEPRGDKAEEVIASIQPNLVLLDIMLPGKDGMSICRDL
RGKYAGPIVLLTSLDSDMNHILALELGACDYILKTTPPAVLLARLRLHLRQNELTQQSKGIQDSVLKMHSTLCFGSLSID
PINRSVLLAGEEVVLSTADFELLWELATHAGQIMDRDALLMSLRGVSYDGLDRSVDVAVSRLRKKLLDNAAEPYRIKTIR
NKGYLFAPHAWE

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=82.0083682008368, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=31.7596566523605, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=33.0472103004292, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=186, Percent_Identity=37.0967741935484, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=32.034632034632, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=31.0924369747899, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=28.2051282051282, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=28.448275862069, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787229, Length=212, Percent_Identity=29.2452830188679, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786911, Length=233, Percent_Identity=28.3261802575107, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=30.1310043668122, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=28.3261802575107, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=27.5423728813559, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787375, Length=244, Percent_Identity=25.8196721311475, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28000; Mature: 27869

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVYGEVFISTMNIMNTLVFVEDDAEVGSLIAAYLAKHDLNVIVEPRGDKAEEVIASIQP
CCCHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCC
NLVLLDIMLPGKDGMSICRDLRGKYAGPIVLLTSLDSDMNHILALELGACDYILKTTPPA
CEEEEEEEECCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEHHCCCHH
VLLARLRLHLRQNELTQQSKGIQDSVLKMHSTLCFGSLSIDPINRSVLLAGEEVVLSTAD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCEECCCCCEEEEECCEEEEECCC
FELLWELATHAGQIMDRDALLMSLRGVSYDGLDRSVDVAVSRLRKKLLDNAAEPYRIKTI
HHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE
RNKGYLFAPHAWE
ECCCEEECCCCCC
>Mature Secondary Structure 
PVYGEVFISTMNIMNTLVFVEDDAEVGSLIAAYLAKHDLNVIVEPRGDKAEEVIASIQP
CCHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCC
NLVLLDIMLPGKDGMSICRDLRGKYAGPIVLLTSLDSDMNHILALELGACDYILKTTPPA
CEEEEEEEECCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEHHCCCHH
VLLARLRLHLRQNELTQQSKGIQDSVLKMHSTLCFGSLSIDPINRSVLLAGEEVVLSTAD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCEECCCCCEEEEECCEEEEECCC
FELLWELATHAGQIMDRDALLMSLRGVSYDGLDRSVDVAVSRLRKKLLDNAAEPYRIKTI
HHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE
RNKGYLFAPHAWE
ECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]