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The map label for this gene is ydhB [H]

Identifier: 218548746

GI number: 218548746

Start: 1422097

End: 1423029

Strand: Direct

Name: ydhB [H]

Synonym: EFER_1385

Alternate gene names: 218548746

Gene position: 1422097-1423029 (Clockwise)

Preceding gene: 218548743

Following gene: 218548748

Centisome position: 30.99

GC content: 51.13

Gene sequence:

>933_bases
ATGTGGTCTGAATACTCTCTTGAAGTGGTTGATGCGGTGGCGCGCAATGGCAGCTTTAGCGCAGCAGCACAGGAATTACA
TCGAGTGCCTTCTGCCGTCAGCTATACCGTAAGACAACTGGAAGAATGGTTAGCGGTGCCTCTTTTCGAACGCCGACACC
GTGATGTAGAACTGACTCCGGCGGGAGCATGGTTTCTGAAAGAGGGGCGATCTGTTATCAAAAAAATGCAGATCACGCGA
CAACAATGCCAGCAAATTGCCAATGGGTGGCGAGGTGAGTTGGCCATCGCGGTGGATAACATTGTTCGTCCAGAACGTAC
ACGTCAATTGATCGTCGATTTTTACCGTCATTTTGACGATGTTGAATTGCGCGTATTCCAGGAAGTCTTCAATGGTGTCT
GGGATGCACTGGCTGACGGACGTGTGGAACTGGCTATAGGCGCGACACAAGCGATTCCTGTAGGGGGGCGCTATACGTTT
CGCGATATGGGAATGTTGAGTTGGTGTTGCGTGGTTGCCAGTCATCATCCACTGGCAGCAATGCCGGGGCCATTAAGTGA
TGATACGTTGCGCAACTGGCCCTCGTTGGTGCGTGAAGACACATCAAGAAATCTACCAAAACGTATTACCTGGTTGTTGG
ATAACCAAAAAAGGGTAGTGGTACCGGACTGGGAGTCTTCAGCTACCTGTATTTCCGCTGGGTTATGCATGGCGATGGTA
CCTACGCATTTTGCCAAGCCGTGGATCGACAGCGGTAAATGGGTAGCGCTACAGCTTGAAAATCCATTCCCGGACGCTGC
CTGTTGTCTTACCTGGCAGCAAAACGATATGTCACCAGCGCTCGCCTGGTTGCTGGATTATCTGGGAGACAGCGAAACGC
TGAATAAAGAGTGGTTGCGGGAGCCAGAATCGGCTCCCACAAAGACATCTTAA

Upstream 100 bases:

>100_bases
TAGTTATCAGTAAGACATCGGCGCAAAGTGTAGGGAGTGAAATTCTGATTGTGAAACGTTAATATTTGACGGGTGATTTC
AAAAATTTTGTAGGCAGAAT

Downstream 100 bases:

>100_bases
CGACGATAGTCGCGGAAAGGACCATCTGCGACAGAACGACGTTCAATCAGGCGCGGATGTACTTCAATGGATTGCGGTTC
TTCACGCTTATTCACAATAC

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTPAGAWFLKEGRSVIKKMQITR
QQCQQIANGWRGELAIAVDNIVRPERTRQLIVDFYRHFDDVELRVFQEVFNGVWDALADGRVELAIGATQAIPVGGRYTF
RDMGMLSWCCVVASHHPLAAMPGPLSDDTLRNWPSLVREDTSRNLPKRITWLLDNQKRVVVPDWESSATCISAGLCMAMV
PTHFAKPWIDSGKWVALQLENPFPDAACCLTWQQNDMSPALAWLLDYLGDSETLNKEWLREPESAPTKTS

Sequences:

>Translated_310_residues
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTPAGAWFLKEGRSVIKKMQITR
QQCQQIANGWRGELAIAVDNIVRPERTRQLIVDFYRHFDDVELRVFQEVFNGVWDALADGRVELAIGATQAIPVGGRYTF
RDMGMLSWCCVVASHHPLAAMPGPLSDDTLRNWPSLVREDTSRNLPKRITWLLDNQKRVVVPDWESSATCISAGLCMAMV
PTHFAKPWIDSGKWVALQLENPFPDAACCLTWQQNDMSPALAWLLDYLGDSETLNKEWLREPESAPTKTS
>Mature_310_residues
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTPAGAWFLKEGRSVIKKMQITR
QQCQQIANGWRGELAIAVDNIVRPERTRQLIVDFYRHFDDVELRVFQEVFNGVWDALADGRVELAIGATQAIPVGGRYTF
RDMGMLSWCCVVASHHPLAAMPGPLSDDTLRNWPSLVREDTSRNLPKRITWLLDNQKRVVVPDWESSATCISAGLCMAMV
PTHFAKPWIDSGKWVALQLENPFPDAACCLTWQQNDMSPALAWLLDYLGDSETLNKEWLREPESAPTKTS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787949, Length=306, Percent_Identity=92.156862745098, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI1786508, Length=285, Percent_Identity=29.8245614035088, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI87082024, Length=249, Percent_Identity=32.1285140562249, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786713, Length=275, Percent_Identity=30.1818181818182, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789492, Length=280, Percent_Identity=30.7142857142857, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI157672245, Length=175, Percent_Identity=31.4285714285714, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=279, Percent_Identity=21.505376344086, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789204, Length=252, Percent_Identity=25, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35168; Mature: 35168

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTP
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHCCCCEEECC
AGAWFLKEGRSVIKKMQITRQQCQQIANGWRGELAIAVDNIVRPERTRQLIVDFYRHFDD
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCHHHHHHHHHHHHCCCH
VELRVFQEVFNGVWDALADGRVELAIGATQAIPVGGRYTFRDMGMLSWCCVVASHHPLAA
HHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCCCEEHHHHHHHHHHHHHHCCCCCCC
MPGPLSDDTLRNWPSLVREDTSRNLPKRITWLLDNQKRVVVPDWESSATCISAGLCMAMV
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHEECCCCEEEECCCCCCHHHHHHHHHHHHH
PTHFAKPWIDSGKWVALQLENPFPDAACCLTWQQNDMSPALAWLLDYLGDSETLNKEWLR
HHHHCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHC
EPESAPTKTS
CCCCCCCCCC
>Mature Secondary Structure
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTP
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHCCCCEEECC
AGAWFLKEGRSVIKKMQITRQQCQQIANGWRGELAIAVDNIVRPERTRQLIVDFYRHFDD
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCHHHHHHHHHHHHCCCH
VELRVFQEVFNGVWDALADGRVELAIGATQAIPVGGRYTFRDMGMLSWCCVVASHHPLAA
HHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCCCEEHHHHHHHHHHHHHHCCCCCCC
MPGPLSDDTLRNWPSLVREDTSRNLPKRITWLLDNQKRVVVPDWESSATCISAGLCMAMV
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHEECCCCEEEECCCCCCHHHHHHHHHHHHH
PTHFAKPWIDSGKWVALQLENPFPDAACCLTWQQNDMSPALAWLLDYLGDSETLNKEWLR
HHHHCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHC
EPESAPTKTS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]