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The map label for this gene is holE [H]

Identifier: 218548597

GI number: 218548597

Start: 1273011

End: 1273328

Strand: Reverse

Name: holE [H]

Synonym: EFER_1231

Alternate gene names: 218548597

Gene position: 1273328-1273011 (Counterclockwise)

Preceding gene: 218548603

Following gene: 218548596

Centisome position: 27.75

GC content: 46.54

Gene sequence:

>318_bases
ATGAATGAGTCGAGAATCATCAACTCAGACTTGCTATCGAACGCTTCTCTTAGTAACTTTTGCCCGCTATCGAATCAGGA
GAAGCTCATGAAGATTAATCTGGCGCAGCTTGATCAAGTGGAAATGGATAAGGTGAATGTTGACCTTGCCGCCGCAGGAG
TTGCTTTCAAAGAACGTTATAATATGCCGGTTATCGCCGAAGCCGTGGAACGTGAACAACCAGAGCATTTGCGTTCATGG
TTTCGCGAACGACTGATCGCCCATCGCCTCGCTTCTGTTTCTCTTTCACGGTTGCCCTACGAACCCAAAATGAAATAA

Upstream 100 bases:

>100_bases
TAACAACAAACAGAACAGTCCAGCAAATTTTTTTTACAGATGAAGCCATATTTACATTCCCTTTTGTAATAACTTATTAG
CAAGAGCATAACCTTCAATA

Downstream 100 bases:

>100_bases
ATTAGCACTATAATTACAACTCCTTACATGTTGCCTGTTAATTTATAAGCAAATTCTTAACCTATGCTTTAGAGTTGCTA
ACAGGCACTATGAAAAGGAA

Product: DNA polymerase III subunit theta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MNESRIINSDLLSNASLSNFCPLSNQEKLMKINLAQLDQVEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQPEHLRSW
FRERLIAHRLASVSLSRLPYEPKMK

Sequences:

>Translated_105_residues
MNESRIINSDLLSNASLSNFCPLSNQEKLMKINLAQLDQVEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQPEHLRSW
FRERLIAHRLASVSLSRLPYEPKMK
>Mature_105_residues
MNESRIINSDLLSNASLSNFCPLSNQEKLMKINLAQLDQVEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQPEHLRSW
FRERLIAHRLASVSLSRLPYEPKMK

Specific function: The exact function of the theta subunit is unknown [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788147, Length=73, Percent_Identity=94.5205479452055, Blast_Score=145, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009052
- InterPro:   IPR011325
- ProDom:   PD057609 [H]

Pfam domain/function: PF06440 DNA_pol3_theta [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 12056; Mature: 12056

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESRIINSDLLSNASLSNFCPLSNQEKLMKINLAQLDQVEMDKVNVDLAAAGVAFKERY
CCCCCCCCHHHHCCCCCCCCCCCCCCCHHHEHHHHHCCCHHHHHCCCHHHHHHHHHHHHC
NMPVIAEAVEREQPEHLRSWFRERLIAHRLASVSLSRLPYEPKMK
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNESRIINSDLLSNASLSNFCPLSNQEKLMKINLAQLDQVEMDKVNVDLAAAGVAFKERY
CCCCCCCCHHHHCCCCCCCCCCCCCCCHHHEHHHHHCCCHHHHHCCCHHHHHHHHHHHHC
NMPVIAEAVEREQPEHLRSWFRERLIAHRLASVSLSRLPYEPKMK
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]