Click here to switch to the map view.

The map label for this gene is acrD [H]

Identifier: 218548097

GI number: 218548097

Start: 723538

End: 726651

Strand: Reverse

Name: acrD [H]

Synonym: EFER_0708

Alternate gene names: 218548097

Gene position: 726651-723538 (Counterclockwise)

Preceding gene: 218548098

Following gene: 218548096

Centisome position: 15.84

GC content: 51.09

Gene sequence:

>3114_bases
ATGGCGAATTTCTTTATTGATCGCCCCATTTTTGCCTGGGTGCTGGCAATCCTGATCTGCCTGACAGGTACCCTGGCGAT
TTTTTCTCTTCCCGTTGAACAGTACCCGGAACTTTCGCCGCCTAATGTGCGTATCTCGGCAAACTATCCGGGCGCTTCGG
CACAAACACTGGAAAATACAGTTACCCAGGTTATCGAGCAAAATATGACCGGACTGGATAACCTGATGTATATGTCGTCG
CAAAGCAGCGGTACAGGCCAGGCATCAGTAACGCTGACTTTCGAAGCGGGTACTGATCCTGACGAAGCCGTTCAACAGGT
ACAAAACCAGCTGCAATCGGCACTGCGTAAGCTACCGCAAGCAGTACAAAATCAGGGCGTGACAGTACGGAAAACCGGTG
ATACCAACATTCTCACCATCGCCTTCGTTTCTACTGATGGTTCGATGGATAAACAAGATATTGCCGATTACGTTGCCAGT
AATATTCAGGACCCGTTAAGTCGCGTGAATGGCGTCGGGGATATCGATGCCTATGGTTCACAATATTCCATGCGTATCTG
GCTGGATCCGGCGAAACTCAATAGTTTCCAGATGACGGCTAAAGATGTCACTGATGCCATTGAGTCACAGAATGCTCAGA
TTGCGGTCGGGCAACTAGGCGGTACGCCGTCAATTCCTCAACAGGCACTGAATGCCACCATCAATGCTCAGTCGCTTTTA
CAAACACCTGAACAGTTTCGCGCAATCACGTTACGCGTTAATCAGGATGGTTCCGAAGTTAAATTAGGTGACGTAGCCAC
TGTTGAAATGGGTGCGGAGAAGTATGACTATCTTAGCCGCTTTAATGGCAATCCGGCATCCGGGCTGGGGGTAAAACTGG
CTTCTGGCGCCAACGAAATGGCGACAGCCAAACGAGTCATTGAGCGGCTGGACGAACTGGCGCAATACTTCCCTCATGGG
CTGGAGTACAAGGTAGCCTATGAAACCACTTCGTTTGTTAAAGCCTCTATTGAAGATGTGGTAAAGACGCTACTGGAAGC
AGTAGCACTGGTATTTCTTGTGATGTATCTGTTTTTGCAGAACATCCGCGCGACACTTATCCCGACCATTGCTGTTCCTG
TGGTGCTGCTTGGCACTTTTGCGGTGCTTTACGCCTTTGATTACAGTATCAACACCCTAACGATGTTTGCGATGGTGCTG
GCGATCGGTCTACTGGTGGATGACGCTATCGTGGTGGTGGAAAACGTCGAACGCATCATGAGTGAAGAAGGATTGTCGCC
TCGCGCAGCCACACGTAAATCAATGGGGCAGATCCAGGGCGCACTGGTCGGCATTGCCATGGTGCTCTCCGCTGTGTTTA
TTCCAATGGCATTTTTTGGTGGCACAACCGGGGCCATTTATCGCCAGTTCTCTATCACCATTGTCTCTGCAATGGTGCTT
TCCGTGTTGGTGGCATTAATACTTACTCCTGCATTGTGCGCCACAATCCTCAAACCATTGCATAAAGGCGAGCAGCACGG
GCAGAAAGGTTTTTTTGGCTGGTTCAACCGCGTGTTTAACCGCAACGCTGATCGCTATGAAAGAGGCGTGGCAAAAATTC
TTCATCGCAGCCTGCGCTGGCTGCTTATTTACCTGTTACTGATTAGCGGCATGGTGGTTTTATTTATGCGCCTGCCCTCT
TCGTTTTTGCCGCAGGAAGACCGTGGAATGTTTACCACGTCAGTACAGTTACCCAGCGGCTCCACTCAACAACAAACCCT
GAAAGTTGTCGAGCAAGTGGAGAAGTATTTCTTCACTCACGAGAAAGATAACATTATGTCGGTGTTTGCCACCGTCGGTT
CCGGGCCTGGGGGTAACGGTCAGAACGTAGCCCGCATGTTTGTTCGCCTGAAAGACTGGGATGATCGCGATCCGAAAACC
GGCAGTGCTTTTGCCATTATTGATCGCGCCACACAAGCTTTTAAGAAGATCAACGAAGCGAAAGTGACTGCCAGTAATCC
ACCGTCGATCAGCGGTCTTGGTAGTTCTGCTGGTTTCGATATGGAATTACAGGATCACGCCGGAGCGGGACACGACGCGT
TGATGGCCGCCAGAGACAAACTGCTGGAACTGGCGGGCAAAGATCCTTCCCTGACACGTGTTCGGCATAATGGTCTCGAC
GACAGTCCACAGTTACAAATTGATATCGACCAGCGTAAAGCACAGGCACTGGGGCTCTCCATTGATGATATTAACGATAC
CCTGCAAACGGCCTGGGGCTCTAGTTACGTTAACGACTTTATGGATCGTGGCCGTGTGAAGAAGGTTTATGTGCAGGCCG
CTGCGCCGTATCGCATGCTGCCAGACGATATTAATCTGTGGTATGTACGCAATAAAGATGGCGGCATGGTGCCTTTTTCC
GCTTTTGCGACCTCTCGTTGGGAGACCGGCTCGCCACGCCTGGAGCGCTATAATGGCTATTCGGCAGTTGAAATTGTCGG
TGAAGCTGCCAGAGGCGTGAGCACGGGAACGGCGATGGAGATTATGGAAAATCTGGTGCATCAGCTGCCCGGTGGATTCG
GACTGGAGTGGACAGCAATGTCGTATCAGGAGCGGCTTTCCGGTGCCCAGGCCCCGGCACTGTATGCGATTTCGTTGCTG
GTTATCTTCCTGTGCCTTGCTGCATTGTATGAAAGTTGGTCCGTCCCCTTCTCCGTCATGTTAGTTGTGCCACTGGGTGT
GGTGGGGGCGCTACTGGCAACCTGGATGCGCGGACTGGAAAACGATGTCTATTTCAAAGTGGGGTTGTTAACAGTAATTG
GCCTTGCAGCGAAGAACGCCATTCTGATTGTTGAATTCGCCAATGATATGAATCAGAAAGGACATGATTTGCTGGAAGCG
ACGCTCCATGCCTGTCGCCAGCGTTTACGTCCAATTTTGATGACATCGCTGGCATTTATTTTCGGCGTATTGCCAATGGC
GATCAGCAATGGTGCGGGCTCTGCCAGCCAACATGCAGTAGGTACAGGTGTAATGGGCGGGATGATTTCGGCGACTATTC
TCGCCATATACTTCGTGCCGCTATTCTTTGTCCTGGTGCGTCGCCGCTTCCCACTGAAGCCGCGCCCGGAATAA

Upstream 100 bases:

>100_bases
CATTATCTCCTTTTTTTCTCCACGATTGGCCCGTACCTTGCCGCTACAGTGAAACAAGGTATGCCCATAACGATACGCAG
AAACACGAGGTTCTCTTTTA

Downstream 100 bases:

>100_bases
TCAAACAAAAAGGCGACTTGCCAATGAGTCGCCTTTTCCATCTTTATGATTTATAGCCCTGGACTCAGGGCCTGATGTTA
CGCATTTCGTCCAGAAGCTT

Product: aminoglycoside/multidrug efflux system

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Acriflavine resistance protein D [H]

Number of amino acids: Translated: 1037; Mature: 1036

Protein sequence:

>1037_residues
MANFFIDRPIFAWVLAILICLTGTLAIFSLPVEQYPELSPPNVRISANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS
QSSGTGQASVTLTFEAGTDPDEAVQQVQNQLQSALRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSIPQQALNATINAQSLL
QTPEQFRAITLRVNQDGSEVKLGDVATVEMGAEKYDYLSRFNGNPASGLGVKLASGANEMATAKRVIERLDELAQYFPHG
LEYKVAYETTSFVKASIEDVVKTLLEAVALVFLVMYLFLQNIRATLIPTIAVPVVLLGTFAVLYAFDYSINTLTMFAMVL
AIGLLVDDAIVVVENVERIMSEEGLSPRAATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGTTGAIYRQFSITIVSAMVL
SVLVALILTPALCATILKPLHKGEQHGQKGFFGWFNRVFNRNADRYERGVAKILHRSLRWLLIYLLLISGMVVLFMRLPS
SFLPQEDRGMFTTSVQLPSGSTQQQTLKVVEQVEKYFFTHEKDNIMSVFATVGSGPGGNGQNVARMFVRLKDWDDRDPKT
GSAFAIIDRATQAFKKINEAKVTASNPPSISGLGSSAGFDMELQDHAGAGHDALMAARDKLLELAGKDPSLTRVRHNGLD
DSPQLQIDIDQRKAQALGLSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS
AFATSRWETGSPRLERYNGYSAVEIVGEAARGVSTGTAMEIMENLVHQLPGGFGLEWTAMSYQERLSGAQAPALYAISLL
VIFLCLAALYESWSVPFSVMLVVPLGVVGALLATWMRGLENDVYFKVGLLTVIGLAAKNAILIVEFANDMNQKGHDLLEA
TLHACRQRLRPILMTSLAFIFGVLPMAISNGAGSASQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRPE

Sequences:

>Translated_1037_residues
MANFFIDRPIFAWVLAILICLTGTLAIFSLPVEQYPELSPPNVRISANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS
QSSGTGQASVTLTFEAGTDPDEAVQQVQNQLQSALRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSIPQQALNATINAQSLL
QTPEQFRAITLRVNQDGSEVKLGDVATVEMGAEKYDYLSRFNGNPASGLGVKLASGANEMATAKRVIERLDELAQYFPHG
LEYKVAYETTSFVKASIEDVVKTLLEAVALVFLVMYLFLQNIRATLIPTIAVPVVLLGTFAVLYAFDYSINTLTMFAMVL
AIGLLVDDAIVVVENVERIMSEEGLSPRAATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGTTGAIYRQFSITIVSAMVL
SVLVALILTPALCATILKPLHKGEQHGQKGFFGWFNRVFNRNADRYERGVAKILHRSLRWLLIYLLLISGMVVLFMRLPS
SFLPQEDRGMFTTSVQLPSGSTQQQTLKVVEQVEKYFFTHEKDNIMSVFATVGSGPGGNGQNVARMFVRLKDWDDRDPKT
GSAFAIIDRATQAFKKINEAKVTASNPPSISGLGSSAGFDMELQDHAGAGHDALMAARDKLLELAGKDPSLTRVRHNGLD
DSPQLQIDIDQRKAQALGLSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS
AFATSRWETGSPRLERYNGYSAVEIVGEAARGVSTGTAMEIMENLVHQLPGGFGLEWTAMSYQERLSGAQAPALYAISLL
VIFLCLAALYESWSVPFSVMLVVPLGVVGALLATWMRGLENDVYFKVGLLTVIGLAAKNAILIVEFANDMNQKGHDLLEA
TLHACRQRLRPILMTSLAFIFGVLPMAISNGAGSASQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRPE
>Mature_1036_residues
ANFFIDRPIFAWVLAILICLTGTLAIFSLPVEQYPELSPPNVRISANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQ
SSGTGQASVTLTFEAGTDPDEAVQQVQNQLQSALRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASN
IQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSIPQQALNATINAQSLLQ
TPEQFRAITLRVNQDGSEVKLGDVATVEMGAEKYDYLSRFNGNPASGLGVKLASGANEMATAKRVIERLDELAQYFPHGL
EYKVAYETTSFVKASIEDVVKTLLEAVALVFLVMYLFLQNIRATLIPTIAVPVVLLGTFAVLYAFDYSINTLTMFAMVLA
IGLLVDDAIVVVENVERIMSEEGLSPRAATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGTTGAIYRQFSITIVSAMVLS
VLVALILTPALCATILKPLHKGEQHGQKGFFGWFNRVFNRNADRYERGVAKILHRSLRWLLIYLLLISGMVVLFMRLPSS
FLPQEDRGMFTTSVQLPSGSTQQQTLKVVEQVEKYFFTHEKDNIMSVFATVGSGPGGNGQNVARMFVRLKDWDDRDPKTG
SAFAIIDRATQAFKKINEAKVTASNPPSISGLGSSAGFDMELQDHAGAGHDALMAARDKLLELAGKDPSLTRVRHNGLDD
SPQLQIDIDQRKAQALGLSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFSA
FATSRWETGSPRLERYNGYSAVEIVGEAARGVSTGTAMEIMENLVHQLPGGFGLEWTAMSYQERLSGAQAPALYAISLLV
IFLCLAALYESWSVPFSVMLVVPLGVVGALLATWMRGLENDVYFKVGLLTVIGLAAKNAILIVEFANDMNQKGHDLLEAT
LHACRQRLRPILMTSLAFIFGVLPMAISNGAGSASQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRPE

Specific function: Participates in the efflux of aminoglycosides. Confers resistance to a variety of these substances [H]

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1788814, Length=1037, Percent_Identity=91.6104146576664, Blast_Score=1985, Evalue=0.0,
Organism=Escherichia coli, GI1786667, Length=1019, Percent_Identity=65.7507360157017, Blast_Score=1363, Evalue=0.0,
Organism=Escherichia coli, GI1789666, Length=1032, Percent_Identity=62.984496124031, Blast_Score=1307, Evalue=0.0,
Organism=Escherichia coli, GI1789930, Length=1019, Percent_Identity=60.1570166830226, Blast_Score=1243, Evalue=0.0,
Organism=Escherichia coli, GI1788390, Length=1040, Percent_Identity=30.5769230769231, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1788391, Length=1058, Percent_Identity=29.0170132325142, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1786788, Length=1047, Percent_Identity=22.7316141356256, Blast_Score=212, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR004764 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 113027; Mature: 112896

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANFFIDRPIFAWVLAILICLTGTLAIFSLPVEQYPELSPPNVRISANYPGASAQTLENT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEECCCCCCCHHHHHHH
VTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLTFEAGTDPDEAVQQVQNQLQSALRKLPQ
HHHHHHHHCCCHHHHHEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
AVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQDPLSRVNGVGDIDAYGS
HHHHCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
QYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSIPQQALNATINAQSLL
CEEEEEEECHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCCCCHHHHH
QTPEQFRAITLRVNQDGSEVKLGDVATVEMGAEKYDYLSRFNGNPASGLGVKLASGANEM
CCHHHHEEEEEEECCCCCEEEECCEEEEHHCHHHHHHHHHCCCCCCCCCCEEECCCCHHH
ATAKRVIERLDELAQYFPHGLEYKVAYETTSFVKASIEDVVKTLLEAVALVFLVMYLFLQ
HHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIRATLIPTIAVPVVLLGTFAVLYAFDYSINTLTMFAMVLAIGLLVDDAIVVVENVERIM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEEGLSPRAATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGTTGAIYRQFSITIVSAMVL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SVLVALILTPALCATILKPLHKGEQHGQKGFFGWFNRVFNRNADRYERGVAKILHRSLRW
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLIYLLLISGMVVLFMRLPSSFLPQEDRGMFTTSVQLPSGSTQQQTLKVVEQVEKYFFTH
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
EKDNIMSVFATVGSGPGGNGQNVARMFVRLKDWDDRDPKTGSAFAIIDRATQAFKKINEA
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHC
KVTASNPPSISGLGSSAGFDMELQDHAGAGHDALMAARDKLLELAGKDPSLTRVRHNGLD
EEECCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
DSPQLQIDIDQRKAQALGLSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRML
CCCCEEEEECHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCCCC
PDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAARGVSTGTAME
CCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCHHHHH
IMENLVHQLPGGFGLEWTAMSYQERLSGAQAPALYAISLLVIFLCLAALYESWSVPFSVM
HHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LVVPLGVVGALLATWMRGLENDVYFKVGLLTVIGLAAKNAILIVEFANDMNQKGHDLLEA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHH
TLHACRQRLRPILMTSLAFIFGVLPMAISNGAGSASQHAVGTGVMGGMISATILAIYFVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LFFVLVRRRFPLKPRPE
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ANFFIDRPIFAWVLAILICLTGTLAIFSLPVEQYPELSPPNVRISANYPGASAQTLENT
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEECCCCCCCHHHHHHH
VTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLTFEAGTDPDEAVQQVQNQLQSALRKLPQ
HHHHHHHHCCCHHHHHEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
AVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQDPLSRVNGVGDIDAYGS
HHHHCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
QYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSIPQQALNATINAQSLL
CEEEEEEECHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCCCCHHHHH
QTPEQFRAITLRVNQDGSEVKLGDVATVEMGAEKYDYLSRFNGNPASGLGVKLASGANEM
CCHHHHEEEEEEECCCCCEEEECCEEEEHHCHHHHHHHHHCCCCCCCCCCEEECCCCHHH
ATAKRVIERLDELAQYFPHGLEYKVAYETTSFVKASIEDVVKTLLEAVALVFLVMYLFLQ
HHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIRATLIPTIAVPVVLLGTFAVLYAFDYSINTLTMFAMVLAIGLLVDDAIVVVENVERIM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEEGLSPRAATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGTTGAIYRQFSITIVSAMVL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SVLVALILTPALCATILKPLHKGEQHGQKGFFGWFNRVFNRNADRYERGVAKILHRSLRW
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLIYLLLISGMVVLFMRLPSSFLPQEDRGMFTTSVQLPSGSTQQQTLKVVEQVEKYFFTH
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
EKDNIMSVFATVGSGPGGNGQNVARMFVRLKDWDDRDPKTGSAFAIIDRATQAFKKINEA
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHC
KVTASNPPSISGLGSSAGFDMELQDHAGAGHDALMAARDKLLELAGKDPSLTRVRHNGLD
EEECCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
DSPQLQIDIDQRKAQALGLSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRML
CCCCEEEEECHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCCCC
PDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAARGVSTGTAME
CCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCHHHHH
IMENLVHQLPGGFGLEWTAMSYQERLSGAQAPALYAISLLVIFLCLAALYESWSVPFSVM
HHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LVVPLGVVGALLATWMRGLENDVYFKVGLLTVIGLAAKNAILIVEFANDMNQKGHDLLEA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHH
TLHACRQRLRPILMTSLAFIFGVLPMAISNGAGSASQHAVGTGVMGGMISATILAIYFVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LFFVLVRRRFPLKPRPE
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 1644752; 10692383 [H]