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The map label for this gene is benK [H]

Identifier: 218236094

GI number: 218236094

Start: 387237

End: 388538

Strand: Reverse

Name: benK [H]

Synonym: BCB4264_A0412

Alternate gene names: 218236094

Gene position: 388538-387237 (Counterclockwise)

Preceding gene: 218232430

Following gene: 218232248

Centisome position: 7.17

GC content: 37.25

Gene sequence:

>1302_bases
ATGCAACCTTCAGCTCCACCTCATCTAGAATCTACAGAAACTATCTTTCCAAGCTCTATTACAAAACTTGTTGTTTTTAT
TTGTTGGCTAGCCATTTTAGCTGATGGATATGATTTAGGTATTTACGGTGCCGTTCTACCAAAGCTTCTAGAAGACAAAA
GCTGGGCGCTATCACCAGCGCATGCTGGTACAATTGCAAGCTATGCTTTATTTGGGATGTTTATTGGAGCTATTCTAGTT
GGAACGATTACAGATCTAATTGGGCGTAAATGGACGCTTATATGCTGTTTAGCACTTTTTTCTATCACAATGGGTTTAGC
GGCTATCGCTCCTTCTCCTGAGTTATTTGGATTATCTCGATTTATAGGAGGAATCGGATTAGGCGGTGTTATCCCTACGG
CTTCAGCACTCACTGTTGAATATTCACCCAAAAAAAGGAAATCTTTTATTTATGCTCTTATGTTTACTGGCTATCCTTTA
GGTATCGTGTTAGGTGCTATTTTGTCCATGCTTATGTTAGAAGATTTCGGATGGAGAATTATGTTTGGTATCGGAATGAT
TCCACTACTCCTCATTCCTTTCATTATTCGCTATTTACCCGAGTCCATTCAATTTTTATTATCACGTAATCGCCAAGAAG
AAGTGAACCAAATTCTTAATCGTTTTCAAATTGAATTTCATATAAAAAATAAAACTCATCAAGCTCCATCTACTATACGA
AAGAAAAATGGATTTTTCACTTTATTCTCAAAAGAATATATAAAAGCAACACTACTTTTTTGGATCACTTATATAATGGG
AATGTTTTTAATATATGGTTTAAACACTTGGTTACCACAGATGATGCGCCAGGCGGGATATCCTCTTGGATCTAGTCTGT
CTTTTCTACTTATGCTAAATATTACCGCAGCTATCGGCGCATTATTTGCTGGAGCAATTGCTGATCGTATAGGCGCAAAA
ATTGTTATTAGCATCTCTTATCTTATGGCAGCCATATGTATCGGACTATTAACAATCAAACCATCTGTTACAATCATTTA
TCTTTTAATTGGCCTTGCTGGTATTGGATCAGTCGGTATTACTCAAATATTAAATGCATATGTAACACAATACTTCCCAT
CACATATCCGAGCTACCTCCTTAGGCTGGGGACTGGGGCTTGGCCGAGTTGGTGCAATTGCTGGCCCAATTCTCGTCGGT
ATTATTATGACAATGCAATATGACTTAGCATGGAATTTTTACTTATTCTCCTTTGCAGGTCTTATCGCAGCTATATCTGT
TTTCTTCATTCCTACAAAATAA

Upstream 100 bases:

>100_bases
TTGTTATAAACCCTTTTCAGATAAAATTCGACACAAGGAGGAAAATATTAACATTAAATAAAATAATATATTCATCTACA
AATTAAAAGGGGTGAATATT

Downstream 100 bases:

>100_bases
AAAGAGCACAAACTTACTTGTGCTCTTTTTCATATGCTTCAAACAACATATCTCGAAACAATGTATTTAAACTCTCAATA
TCGATTCCTGATCCCTTTTC

Product: putative benzoate transport protein

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MQPSAPPHLESTETIFPSSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDKSWALSPAHAGTIASYALFGMFIGAILV
GTITDLIGRKWTLICCLALFSITMGLAAIAPSPELFGLSRFIGGIGLGGVIPTASALTVEYSPKKRKSFIYALMFTGYPL
GIVLGAILSMLMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVNQILNRFQIEFHIKNKTHQAPSTIR
KKNGFFTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRIGAK
IVISISYLMAAICIGLLTIKPSVTIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAGPILVG
IIMTMQYDLAWNFYLFSFAGLIAAISVFFIPTK

Sequences:

>Translated_433_residues
MQPSAPPHLESTETIFPSSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDKSWALSPAHAGTIASYALFGMFIGAILV
GTITDLIGRKWTLICCLALFSITMGLAAIAPSPELFGLSRFIGGIGLGGVIPTASALTVEYSPKKRKSFIYALMFTGYPL
GIVLGAILSMLMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVNQILNRFQIEFHIKNKTHQAPSTIR
KKNGFFTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRIGAK
IVISISYLMAAICIGLLTIKPSVTIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAGPILVG
IIMTMQYDLAWNFYLFSFAGLIAAISVFFIPTK
>Mature_433_residues
MQPSAPPHLESTETIFPSSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDKSWALSPAHAGTIASYALFGMFIGAILV
GTITDLIGRKWTLICCLALFSITMGLAAIAPSPELFGLSRFIGGIGLGGVIPTASALTVEYSPKKRKSFIYALMFTGYPL
GIVLGAILSMLMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVNQILNRFQIEFHIKNKTHQAPSTIR
KKNGFFTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRIGAK
IVISISYLMAAICIGLLTIKPSVTIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAGPILVG
IIMTMQYDLAWNFYLFSFAGLIAAISVFFIPTK

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=434, Percent_Identity=26.2672811059908, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI166064021, Length=367, Percent_Identity=24.2506811989101, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI7662270, Length=309, Percent_Identity=22.3300970873786, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI216548223, Length=308, Percent_Identity=21.7532467532468, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI31542327, Length=376, Percent_Identity=20.7446808510638, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI213021148, Length=412, Percent_Identity=22.5728155339806, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081723, Length=387, Percent_Identity=27.906976744186, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI87082404, Length=421, Percent_Identity=24.2280285035629, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082159, Length=369, Percent_Identity=28.4552845528455, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788074, Length=426, Percent_Identity=24.1784037558685, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786229, Length=409, Percent_Identity=26.8948655256724, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082231, Length=423, Percent_Identity=20.8037825059102, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788068, Length=373, Percent_Identity=25.7372654155496, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789312, Length=333, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1789207, Length=311, Percent_Identity=23.1511254019293, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788292, Length=206, Percent_Identity=28.1553398058252, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=429, Percent_Identity=24.9417249417249, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71989525, Length=351, Percent_Identity=25.3561253561254, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71989531, Length=351, Percent_Identity=25.3561253561254, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322632, Length=126, Percent_Identity=36.5079365079365, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320595, Length=205, Percent_Identity=27.8048780487805, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19922874, Length=432, Percent_Identity=23.8425925925926, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24640198, Length=447, Percent_Identity=21.923937360179, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640196, Length=447, Percent_Identity=21.923937360179, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640200, Length=447, Percent_Identity=21.923937360179, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24668456, Length=373, Percent_Identity=26.2734584450402, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47331; Mature: 47331

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSAPPHLESTETIFPSSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDKSWALSPA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
HAGTIASYALFGMFIGAILVGTITDLIGRKWTLICCLALFSITMGLAAIAPSPELFGLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FIGGIGLGGVIPTASALTVEYSPKKRKSFIYALMFTGYPLGIVLGAILSMLMLEDFGWRI
HHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
MFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVNQILNRFQIEFHIKNKTHQAPSTIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCCCHHHHH
KKNGFFTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLN
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ITAAIGALFAGAIADRIGAKIVISISYLMAAICIGLLTIKPSVTIIYLLIGLAGIGSVGI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
TQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAGPILVGIIMTMQYDLAWNFYLFSFAG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAAISVFFIPTK
HHHHHHHHHCCCC
>Mature Secondary Structure
MQPSAPPHLESTETIFPSSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDKSWALSPA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
HAGTIASYALFGMFIGAILVGTITDLIGRKWTLICCLALFSITMGLAAIAPSPELFGLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FIGGIGLGGVIPTASALTVEYSPKKRKSFIYALMFTGYPLGIVLGAILSMLMLEDFGWRI
HHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
MFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVNQILNRFQIEFHIKNKTHQAPSTIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCCCHHHHH
KKNGFFTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLN
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ITAAIGALFAGAIADRIGAKIVISISYLMAAICIGLLTIKPSVTIIYLLIGLAGIGSVGI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
TQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAGPILVGIIMTMQYDLAWNFYLFSFAG
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAAISVFFIPTK
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]