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The map label for this gene is scrK [H]

Identifier: 218234688

GI number: 218234688

Start: 782963

End: 783904

Strand: Reverse

Name: scrK [H]

Synonym: BCB4264_A0808

Alternate gene names: 218234688

Gene position: 783904-782963 (Counterclockwise)

Preceding gene: 218232203

Following gene: 218235926

Centisome position: 14.47

GC content: 35.99

Gene sequence:

>942_bases
ATGAGAAATGTCTTTTGTATAGGTGAACTATTAATTGATTTTGTGTGCCGAAATACTAATGTTTCTTTAGTAAACGGTTC
AGATTTCGAAAAAAAAGCTGGTGGAGCACCCGCTAACGTTGCTGCTGCGATTACAAAATTAGGTGGACACGCTACATTTA
TGGGGCAAGTAGGAAACGACCCATTTGGTGAGTTTCTTGAACAAACTTTACAGCGTGCGAAAGTCGATACATCCATGCTC
ATAAAAGATAAACAAACAACACTTGCATTCGTATCCATCGATCAAGATGGCGAACGTGATTTTACTTTTATGCGTGGTGC
AGATGGTGAATATCAATTCAATAGCATTGATTTATCAAAAATACAAACGAATGATTTAATACATTTCGGTTCAGCGACAG
CTTTACTATCAAGCCCATTAAAAGAAACGTATTTTCAGTTGTTACAATATGCGAAAGATAAAGGTCATTTTATTTCTTTT
GATCCAAATTATCGAAGTGCACTCATTACAAATACAGAACAATTCTCTCAAGATTGTCTAACCTTTATAAAACATGCACA
CTTCGTAAAAGTAAGTCAAGAGGAAGCTACTATGCTCTCTAAAGAGATTGATTTACAACAAGCTGCACTCAAATTATTAA
ATTATGGCGCAAAAGTAGTAGCTATTACACTTGGAAAAGACGGTACCCTTCTTGCGACAAATGAAGGTCAAACTATTGTC
TCTTCTATTTCCATTCAACAAGTCGATACAACTGGTGCTGGTGATGCTTTCGTTGGAGCAATGTTATATCAGATTGCCCA
AAGTGAACATACACTTTCGTATCATTTCAAAGACTTAACAGCATTTATCTCCTTTGCCAATAAAGTAGGCGCTATCACAT
GTACAAATTACGGTGCAATTGCCTCTCTTCCATCATTAACAGATATAAAAGCATACGATTAA

Upstream 100 bases:

>100_bases
GAGTTTTTCCTCGAAAAGACATGAAACATCATATCGCAATCTTTTCAGATGCAAAACTAAACTTTACCATCACACAATAT
AAGCTGAAAAGAGGGATTGT

Downstream 100 bases:

>100_bases
TCGTATGCTTTTTTACATCCCTCTCCAAAAATCATGCATAATAAAAAAGTACAAAATAACGAGAACGGCCGTCCCGCATA
GGGTAATGCGCCGATATATA

Product: fructokinase

Products: ADP; D-fructose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRNVFCIGELLIDFVCRNTNVSLVNGSDFEKKAGGAPANVAAAITKLGGHATFMGQVGNDPFGEFLEQTLQRAKVDTSML
IKDKQTTLAFVSIDQDGERDFTFMRGADGEYQFNSIDLSKIQTNDLIHFGSATALLSSPLKETYFQLLQYAKDKGHFISF
DPNYRSALITNTEQFSQDCLTFIKHAHFVKVSQEEATMLSKEIDLQQAALKLLNYGAKVVAITLGKDGTLLATNEGQTIV
SSISIQQVDTTGAGDAFVGAMLYQIAQSEHTLSYHFKDLTAFISFANKVGAITCTNYGAIASLPSLTDIKAYD

Sequences:

>Translated_313_residues
MRNVFCIGELLIDFVCRNTNVSLVNGSDFEKKAGGAPANVAAAITKLGGHATFMGQVGNDPFGEFLEQTLQRAKVDTSML
IKDKQTTLAFVSIDQDGERDFTFMRGADGEYQFNSIDLSKIQTNDLIHFGSATALLSSPLKETYFQLLQYAKDKGHFISF
DPNYRSALITNTEQFSQDCLTFIKHAHFVKVSQEEATMLSKEIDLQQAALKLLNYGAKVVAITLGKDGTLLATNEGQTIV
SSISIQQVDTTGAGDAFVGAMLYQIAQSEHTLSYHFKDLTAFISFANKVGAITCTNYGAIASLPSLTDIKAYD
>Mature_313_residues
MRNVFCIGELLIDFVCRNTNVSLVNGSDFEKKAGGAPANVAAAITKLGGHATFMGQVGNDPFGEFLEQTLQRAKVDTSML
IKDKQTTLAFVSIDQDGERDFTFMRGADGEYQFNSIDLSKIQTNDLIHFGSATALLSSPLKETYFQLLQYAKDKGHFISF
DPNYRSALITNTEQFSQDCLTFIKHAHFVKVSQEEATMLSKEIDLQQAALKLLNYGAKVVAITLGKDGTLLATNEGQTIV
SSISIQQVDTTGAGDAFVGAMLYQIAQSEHTLSYHFKDLTAFISFANKVGAITCTNYGAIASLPSLTDIKAYD

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=25.3378378378378, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081971, Length=311, Percent_Identity=24.7588424437299, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790193, Length=297, Percent_Identity=26.5993265993266, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082281, Length=277, Percent_Identity=22.7436823104693, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20128807, Length=286, Percent_Identity=24.4755244755245, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.4

Molecular weight: Translated: 34140; Mature: 34140

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNVFCIGELLIDFVCRNTNVSLVNGSDFEKKAGGAPANVAAAITKLGGHATFMGQVGND
CCCEEHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCEEEEECCCCC
PFGEFLEQTLQRAKVDTSMLIKDKQTTLAFVSIDQDGERDFTFMRGADGEYQFNSIDLSK
HHHHHHHHHHHHHHCCHHHEEECCCCEEEEEEECCCCCCCEEEEECCCCCEEECEEEHHH
IQTNDLIHFGSATALLSSPLKETYFQLLQYAKDKGHFISFDPNYRSALITNTEQFSQDCL
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECHHHHHHHHH
TFIKHAHFVKVSQEEATMLSKEIDLQQAALKLLNYGAKVVAITLGKDGTLLATNEGQTIV
HHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEEE
SSISIQQVDTTGAGDAFVGAMLYQIAQSEHTLSYHFKDLTAFISFANKVGAITCTNYGAI
EEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCEEEECCCCCH
ASLPSLTDIKAYD
HCCCCCCCCCCCC
>Mature Secondary Structure
MRNVFCIGELLIDFVCRNTNVSLVNGSDFEKKAGGAPANVAAAITKLGGHATFMGQVGND
CCCEEHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCEEEEECCCCC
PFGEFLEQTLQRAKVDTSMLIKDKQTTLAFVSIDQDGERDFTFMRGADGEYQFNSIDLSK
HHHHHHHHHHHHHHCCHHHEEECCCCEEEEEEECCCCCCCEEEEECCCCCEEECEEEHHH
IQTNDLIHFGSATALLSSPLKETYFQLLQYAKDKGHFISFDPNYRSALITNTEQFSQDCL
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECHHHHHHHHH
TFIKHAHFVKVSQEEATMLSKEIDLQQAALKLLNYGAKVVAITLGKDGTLLATNEGQTIV
HHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEEE
SSISIQQVDTTGAGDAFVGAMLYQIAQSEHTLSYHFKDLTAFISFANKVGAITCTNYGAI
EEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCEEEECCCCCH
ASLPSLTDIKAYD
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-fructose

Specific reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]