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The map label for this gene is resE [H]

Identifier: 218233945

GI number: 218233945

Start: 676210

End: 677601

Strand: Reverse

Name: resE [H]

Synonym: BCB4264_A0686

Alternate gene names: 218233945

Gene position: 677601-676210 (Counterclockwise)

Preceding gene: 218236076

Following gene: 218231818

Centisome position: 12.5

GC content: 33.84

Gene sequence:

>1392_bases
ATGAAACGAATTTCAATTCAATTCGGATTTTATTTTTTAATTGTTACACTTTTAATTGAAAGTGTTCTCTTTATTTTGCT
CTATTATAGTCTTGTAAACACTAGAGTAAATGAAGAAATGACAGCTTTATTAAAGCGAGGAAATAGTCATCGAGATGTAC
TTGAAAAATATTACGATGAGCAAACCATCTCTCACGTAGCATTAATGGAATCTGAAGCTGAAACAACTGTCGTTATTACA
AATGCAAATAAAGAAATACTAGCTAAATCTAACGAAATAAACACGACTATAAACGATCATATTAGTAAAATGCAAACTCG
AACAGACCATAATGGAGCGATTATAGAAAATCATTGGAAAACATCTAATTATATATGTACAGTTAGCCCCATTGTAGTAG
ATGGAAAACATGAAGGCTATGTGTACATGTTTCTTGGAACAGAATCAATTGAAAAGTTAGTTAATGGATTAACGAAACAA
TTCATTATTGCTGGTGCCATCACATTTCTACTCACAGTCATCACAATTTTCCTATTATCACGTTTATTAACAAAACCATT
GTTACACATGAAACATGCAACTGAAAAAATGAGTAAAGGCGATTTGTCCGTTTCGTTAACGACTACTCGTAATGATGAAA
TTGGTGAACTGGCATCATCTATTCAAACGCTCGCAAATGATTTGCATTATATGAAAACAGAGCGAAGTGAATTTCTAGCA
AGTGTTGCTCACGAATTACGAACACCGTTAACATACGTAAGAGGTTATGCTGACATTGCTTTAAAAGAAAGCACCCCTTC
TGAACAACGTTTGCGATATTTATCAATTATAAAAGATGAGTCTGATTACATTACAAACTTAGTTCAAGATTTATTTTCAC
TTGCACAAATGGAACAACATAACTTTTCTATTCAAGTAAAGGAAGTGCATTTACACACCTTCCTTACGCGTATATGTGAA
AAAGTAAACGCCATGTATAAAGAAAGGTACATTAAAGTTTCTTTCTCTTGTCCTCCTACACTGCTAGTAAACTTAGATGA
ACAACGATTCGAACAAGTTGTGGTGAATATTTTAAATAACGCTTATAGACATTCAAAAGAGCATTCTCATATAAACATTT
CTGTTACAGAAGAACATAAACATATTTCCATTGCAATTGAAGATGAAGGCGAAGGTATTCCGCTTGAAGACCTCCCTCAC
ATTTTTGACCGCTTTTATCGAGTTGATAAAGCAAGATCACGAGCTACAGGTGGAACTGGTTTAGGACTATCTATCGTGAA
AGAAATTGTAGAGTTACACGGCGGGACGATTACTGTCACGAGTGAAGTTGATCATGGATCTTGTTTTATCATTTCATTAC
CATCTGTAAAGAAACACGACTACCATCAGTAG

Upstream 100 bases:

>100_bases
ATAAATTGCGAAAAGCAAATTTTCCTATTGATCATCATTTAAAAACCGTGTATGGAATAGGTTATCGATGGATTGATACT
GAACAGTAAGGGGCAAAACG

Downstream 100 bases:

>100_bases
TCGTGTTTCTTTATCATTTTACTTTATAATATAAATTTACAAATTGCCCAAAACGTTTCGTATCCGTCAAAGTTAAATTA
ATTTCTGGGTTCTTGTCTTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKRISIQFGFYFLIVTLLIESVLFILLYYSLVNTRVNEEMTALLKRGNSHRDVLEKYYDEQTISHVALMESEAETTVVIT
NANKEILAKSNEINTTINDHISKMQTRTDHNGAIIENHWKTSNYICTVSPIVVDGKHEGYVYMFLGTESIEKLVNGLTKQ
FIIAGAITFLLTVITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKESTPSEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRICE
KVNAMYKERYIKVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSHINISVTEEHKHISIAIEDEGEGIPLEDLPH
IFDRFYRVDKARSRATGGTGLGLSIVKEIVELHGGTITVTSEVDHGSCFIISLPSVKKHDYHQ

Sequences:

>Translated_463_residues
MKRISIQFGFYFLIVTLLIESVLFILLYYSLVNTRVNEEMTALLKRGNSHRDVLEKYYDEQTISHVALMESEAETTVVIT
NANKEILAKSNEINTTINDHISKMQTRTDHNGAIIENHWKTSNYICTVSPIVVDGKHEGYVYMFLGTESIEKLVNGLTKQ
FIIAGAITFLLTVITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKESTPSEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRICE
KVNAMYKERYIKVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSHINISVTEEHKHISIAIEDEGEGIPLEDLPH
IFDRFYRVDKARSRATGGTGLGLSIVKEIVELHGGTITVTSEVDHGSCFIISLPSVKKHDYHQ
>Mature_463_residues
MKRISIQFGFYFLIVTLLIESVLFILLYYSLVNTRVNEEMTALLKRGNSHRDVLEKYYDEQTISHVALMESEAETTVVIT
NANKEILAKSNEINTTINDHISKMQTRTDHNGAIIENHWKTSNYICTVSPIVVDGKHEGYVYMFLGTESIEKLVNGLTKQ
FIIAGAITFLLTVITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKESTPSEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRICE
KVNAMYKERYIKVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSHINISVTEEHKHISIAIEDEGEGIPLEDLPH
IFDRFYRVDKARSRATGGTGLGLSIVKEIVELHGGTITVTSEVDHGSCFIISLPSVKKHDYHQ

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=277, Percent_Identity=30.6859205776173, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1786783, Length=348, Percent_Identity=28.1609195402299, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=31.2741312741313, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=30.2788844621514, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1790346, Length=338, Percent_Identity=26.3313609467456, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787894, Length=286, Percent_Identity=26.2237762237762, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=27.0161290322581, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=27.3858921161826, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=30.5555555555556, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI48994928, Length=237, Percent_Identity=29.535864978903, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87081816, Length=336, Percent_Identity=25.297619047619, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=28.6995515695067, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790861, Length=385, Percent_Identity=22.0779220779221, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082128, Length=304, Percent_Identity=23.6842105263158, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=30.8035714285714, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789808, Length=290, Percent_Identity=27.9310344827586, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788279, Length=320, Percent_Identity=26.25, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=28.2685512367491, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787374, Length=299, Percent_Identity=24.4147157190635, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790300, Length=249, Percent_Identity=28.1124497991968, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789403, Length=324, Percent_Identity=25.6172839506173, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52759; Mature: 52759

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRISIQFGFYFLIVTLLIESVLFILLYYSLVNTRVNEEMTALLKRGNSHRDVLEKYYDE
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QTISHVALMESEAETTVVITNANKEILAKSNEINTTINDHISKMQTRTDHNGAIIENHWK
HHHHHHHHHCCCCCEEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCC
TSNYICTVSPIVVDGKHEGYVYMFLGTESIEKLVNGLTKQFIIAGAITFLLTVITIFLLS
CCCEEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAHELRTPLTYVRGYADIALKESTPSEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQH
HHHHHHHCCHHHHCCHHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
NFSIQVKEVHLHTFLTRICEKVNAMYKERYIKVSFSCPPTLLVNLDEQRFEQVVVNILNN
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHHHHHHHHHHH
AYRHSKEHSHINISVTEEHKHISIAIEDEGEGIPLEDLPHIFDRFYRVDKARSRATGGTG
HHHCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
LGLSIVKEIVELHGGTITVTSEVDHGSCFIISLPSVKKHDYHQ
CCHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKRISIQFGFYFLIVTLLIESVLFILLYYSLVNTRVNEEMTALLKRGNSHRDVLEKYYDE
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QTISHVALMESEAETTVVITNANKEILAKSNEINTTINDHISKMQTRTDHNGAIIENHWK
HHHHHHHHHCCCCCEEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCC
TSNYICTVSPIVVDGKHEGYVYMFLGTESIEKLVNGLTKQFIIAGAITFLLTVITIFLLS
CCCEEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELASSIQTLANDLHYMKTERSEFLA
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAHELRTPLTYVRGYADIALKESTPSEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQH
HHHHHHHCCHHHHCCHHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
NFSIQVKEVHLHTFLTRICEKVNAMYKERYIKVSFSCPPTLLVNLDEQRFEQVVVNILNN
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHHHHHHHHHHH
AYRHSKEHSHINISVTEEHKHISIAIEDEGEGIPLEDLPHIFDRFYRVDKARSRATGGTG
HHHCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
LGLSIVKEIVELHGGTITVTSEVDHGSCFIISLPSVKKHDYHQ
CCHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]