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The map label for this gene is yclF [H]

Identifier: 218233391

GI number: 218233391

Start: 711895

End: 713280

Strand: Reverse

Name: yclF [H]

Synonym: BCB4264_A0721

Alternate gene names: 218233391

Gene position: 713280-711895 (Counterclockwise)

Preceding gene: 218230996

Following gene: 218231066

Centisome position: 13.16

GC content: 38.1

Gene sequence:

>1386_bases
ATGGAATCAGCGATACAACTAGAAAGAGAACAACAAAGAAAAAAGAAACATCCTCCAGGTTTATACTTACTCTTCTTTAC
AGAAATGTGGGAAAGATTTAGTTACTATGGATTACGAGGATTATTAACATTATATTTAACGACAGCTTTAGTAAGCGGTG
GTCTTGGGTTTAGTCCCGCATGGGCACTCTCTATTTACGGATTTTACACTGGAGCCTGTTATTTCACACCAATGATTGGT
GGATACTTAACAGACCGTTTTCTAGGTAGACGAAAAGCAATCACAATTGGTGGTATAACAATGGCAATCGGTAACCTTAC
ACTATTTGCCTTGCAAAACCAATTAGGCCTATACCTCGGATTAGCGCTTATTATTATCGGTAACGGATTCTTCAAACCGA
ACATCTCTACACTGGTTGGGGAATTATACGAAGAGAACGATCCAAAACGTGATAGTGCATTTACCATTTTCTATATGGGT
ATTAACGTCGGGTCATTTTTAGCTCCACTCGTTTGCGGATTTTTATCAGAAAATTTATTCAAAACAACAGTTGATGGCGT
TGTACATTACGGATTCCGTTACGGTTTCTTAGCCGCTTCAATCGGAATGATTATTGGACAAATTTTATTTACAACACTAT
CAAATCGCTTCCTTGGTAATATCGGTAAAAAACCAACTCGCGATTTACAAACAGCTGCTGGACAACCATCAGTAGGAGAT
ACACCATTAACAAAAAAAGAAAAACAACGTACCGCAGTTATCGTCATTTTAACATGCTTCGTTGTCTTCTTCTGGGCTGG
CTTTGAACAAGCTGGTAGCTCATTAACATTATATACAAACAAATTTGTAGACCGCTCTGTGTTCGGATGGGAAGTTCCAA
CATCTTGGTTCCAATCAGTCAATCCATTATTTATTATTTTGCTTGCTCCAGTCATTTCTGCATTATGGGCAAAACTTGCA
ACTCGCAAGCAGGGTGATTTAAAAATCCCAACTAAAATGGGACTTGGTATGATCTTGCTCGGTATCGGTTATATCATTCT
CGTTATCGCTACATTAAAAACAGGTAGTGATGAACATAACATTACAGAAAAAGCAAACTTACTGTTTATCGTCTTTACGT
ATCTTTTCCATACGTTAGGTGAGCTATTCTTATCACCTGTCGGACTATCAATGGTTAGTGCGCTTGCTCCGGTAAAATTA
GCATCTTTACTAATGGGTGTATGGCTAGCAAGTTCAGGTATCGCCAACATTTTAGGCGGACAACTTGCAAGCTTCACAAC
TTCACTTGGATACGCTGAAGTATTCACAGTTATTGGCGCTGTGGCAATTGTACTAGGTTGTGTTTTATTATTAATTTCTA
AGAAATTAGTGAAATGGATGGATTAA

Upstream 100 bases:

>100_bases
GAAAAATCAACCTTTATTGACTTATAATAGTTAATAAGGTAAAATATTAAATGTACAAAATTATTAACTTTGTTTTTGTT
TGTGTCAGGAGGAAAATAAC

Downstream 100 bases:

>100_bases
AAAAAGATGAGGAATTTCTCCTCATCTTTTTTTATGCTGTTTTACCTTGTTCTATTGCTTGTTCGTACAGCTCTTTATGT
TCTTTATATTCACTTGGTAC

Product: proton/peptide symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MESAIQLEREQQRKKKHPPGLYLLFFTEMWERFSYYGLRGLLTLYLTTALVSGGLGFSPAWALSIYGFYTGACYFTPMIG
GYLTDRFLGRRKAITIGGITMAIGNLTLFALQNQLGLYLGLALIIIGNGFFKPNISTLVGELYEENDPKRDSAFTIFYMG
INVGSFLAPLVCGFLSENLFKTTVDGVVHYGFRYGFLAASIGMIIGQILFTTLSNRFLGNIGKKPTRDLQTAAGQPSVGD
TPLTKKEKQRTAVIVILTCFVVFFWAGFEQAGSSLTLYTNKFVDRSVFGWEVPTSWFQSVNPLFIILLAPVISALWAKLA
TRKQGDLKIPTKMGLGMILLGIGYIILVIATLKTGSDEHNITEKANLLFIVFTYLFHTLGELFLSPVGLSMVSALAPVKL
ASLLMGVWLASSGIANILGGQLASFTTSLGYAEVFTVIGAVAIVLGCVLLLISKKLVKWMD

Sequences:

>Translated_461_residues
MESAIQLEREQQRKKKHPPGLYLLFFTEMWERFSYYGLRGLLTLYLTTALVSGGLGFSPAWALSIYGFYTGACYFTPMIG
GYLTDRFLGRRKAITIGGITMAIGNLTLFALQNQLGLYLGLALIIIGNGFFKPNISTLVGELYEENDPKRDSAFTIFYMG
INVGSFLAPLVCGFLSENLFKTTVDGVVHYGFRYGFLAASIGMIIGQILFTTLSNRFLGNIGKKPTRDLQTAAGQPSVGD
TPLTKKEKQRTAVIVILTCFVVFFWAGFEQAGSSLTLYTNKFVDRSVFGWEVPTSWFQSVNPLFIILLAPVISALWAKLA
TRKQGDLKIPTKMGLGMILLGIGYIILVIATLKTGSDEHNITEKANLLFIVFTYLFHTLGELFLSPVGLSMVSALAPVKL
ASLLMGVWLASSGIANILGGQLASFTTSLGYAEVFTVIGAVAIVLGCVLLLISKKLVKWMD
>Mature_461_residues
MESAIQLEREQQRKKKHPPGLYLLFFTEMWERFSYYGLRGLLTLYLTTALVSGGLGFSPAWALSIYGFYTGACYFTPMIG
GYLTDRFLGRRKAITIGGITMAIGNLTLFALQNQLGLYLGLALIIIGNGFFKPNISTLVGELYEENDPKRDSAFTIFYMG
INVGSFLAPLVCGFLSENLFKTTVDGVVHYGFRYGFLAASIGMIIGQILFTTLSNRFLGNIGKKPTRDLQTAAGQPSVGD
TPLTKKEKQRTAVIVILTCFVVFFWAGFEQAGSSLTLYTNKFVDRSVFGWEVPTSWFQSVNPLFIILLAPVISALWAKLA
TRKQGDLKIPTKMGLGMILLGIGYIILVIATLKTGSDEHNITEKANLLFIVFTYLFHTLGELFLSPVGLSMVSALAPVKL
ASLLMGVWLASSGIANILGGQLASFTTSLGYAEVFTVIGAVAIVLGCVLLLISKKLVKWMD

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=383, Percent_Identity=25.8485639686684, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI226371746, Length=355, Percent_Identity=27.0422535211268, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI226371748, Length=346, Percent_Identity=26.3005780346821, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1786927, Length=498, Percent_Identity=31.5261044176707, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1790572, Length=458, Percent_Identity=31.0043668122271, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1787922, Length=494, Percent_Identity=29.5546558704453, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1789911, Length=496, Percent_Identity=27.6209677419355, Blast_Score=189, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71987453, Length=378, Percent_Identity=26.4550264550265, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17569141, Length=166, Percent_Identity=30.7228915662651, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571098, Length=367, Percent_Identity=27.5204359673025, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571102, Length=399, Percent_Identity=26.8170426065163, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571100, Length=399, Percent_Identity=26.8170426065163, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24639581, Length=348, Percent_Identity=25.8620689655172, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639585, Length=334, Percent_Identity=26.0479041916168, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639583, Length=334, Percent_Identity=26.0479041916168, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 50473; Mature: 50473

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00501 SPASE_I_1 ; PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAIQLEREQQRKKKHPPGLYLLFFTEMWERFSYYGLRGLLTLYLTTALVSGGLGFSPA
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
WALSIYGFYTGACYFTPMIGGYLTDRFLGRRKAITIGGITMAIGNLTLFALQNQLGLYLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
LALIIIGNGFFKPNISTLVGELYEENDPKRDSAFTIFYMGINVGSFLAPLVCGFLSENLF
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
KTTVDGVVHYGFRYGFLAASIGMIIGQILFTTLSNRFLGNIGKKPTRDLQTAAGQPSVGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCC
TPLTKKEKQRTAVIVILTCFVVFFWAGFEQAGSSLTLYTNKFVDRSVFGWEVPTSWFQSV
CCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEEHHHHCCCCCCCCCCHHHHHCC
NPLFIILLAPVISALWAKLATRKQGDLKIPTKMGLGMILLGIGYIILVIATLKTGSDEHN
CHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ITEKANLLFIVFTYLFHTLGELFLSPVGLSMVSALAPVKLASLLMGVWLASSGIANILGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
QLASFTTSLGYAEVFTVIGAVAIVLGCVLLLISKKLVKWMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MESAIQLEREQQRKKKHPPGLYLLFFTEMWERFSYYGLRGLLTLYLTTALVSGGLGFSPA
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
WALSIYGFYTGACYFTPMIGGYLTDRFLGRRKAITIGGITMAIGNLTLFALQNQLGLYLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
LALIIIGNGFFKPNISTLVGELYEENDPKRDSAFTIFYMGINVGSFLAPLVCGFLSENLF
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
KTTVDGVVHYGFRYGFLAASIGMIIGQILFTTLSNRFLGNIGKKPTRDLQTAAGQPSVGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCC
TPLTKKEKQRTAVIVILTCFVVFFWAGFEQAGSSLTLYTNKFVDRSVFGWEVPTSWFQSV
CCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEEEHHHHCCCCCCCCCCHHHHHCC
NPLFIILLAPVISALWAKLATRKQGDLKIPTKMGLGMILLGIGYIILVIATLKTGSDEHN
CHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ITEKANLLFIVFTYLFHTLGELFLSPVGLSMVSALAPVKLASLLMGVWLASSGIANILGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
QLASFTTSLGYAEVFTVIGAVAIVLGCVLLLISKKLVKWMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]