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The map label for this gene is ina [H]

Identifier: 218230864

GI number: 218230864

Start: 2875401

End: 2877788

Strand: Reverse

Name: ina [H]

Synonym: BCB4264_A3001

Alternate gene names: 218230864

Gene position: 2877788-2875401 (Counterclockwise)

Preceding gene: 218234704

Following gene: 218234936

Centisome position: 53.11

GC content: 39.74

Gene sequence:

>2388_bases
TTGAAAAAGAAAAAGAAATTAAAACCATTAGCGGTATTAACAACAGCAGCAGTACTAAGTAGTACGTTTGCTTTTGGAGG
TCACGCAGCGTATGCTGAGACACCAACATCATCTCTACCAATAGATGAGCACTTAATACCGGAGGAGCGTTTGGCTGAAG
CGCTAAAACAACGGGGGGTAATTGATCAATCTGCATCGCAAGCTGAGACGTCAAAGGCTGTCGAAAAATATGTTGAGAAA
AAGAAAGGGGAAAACCCTGGGAAAGAAATCTTAACAGGAGATAGTCTTACGCAAGAAGCTTCTGATTTTATGAAAAAAGT
AAAAGATGCAAAAATGAAGGAAAATGAACAGGCGCAGCAGCCTGAAGTAGGCCCGGTAGCTGGACAAGGTGCAGCATTGA
ACCCTGGGAAATTAAATGGAAAAGTACCTACTACATCAGCGAAGCAAGAAGAATACAATGGAGCTGTTCGAAAAGATAAA
GTACTTGTTTTACTTGTAGAATTTAGCGATTTTAAGCATAACAATATTGATCAAGAGCCAGGATACATGTATTCTAAAGA
CTTTAATCGTGAACATTATCAAAAAATGTTATTTGGTGATGAACCATTTACTTTATTTGATGGATCGAAGATTAACACAT
TTAAGCAATATTATGAAGAACAATCTGGTGGTAGCTACACAGTTGATGGGACTGTAACAGAATGGCTTACTGTTCCAGGA
AAAGCATCAGATTATGGTGCTGATGCAGGTACTGGGCATGATAACAAGGGGCCTTTAGGACCAAAAGATTTTGTGAAAGA
AGCATTAAAAGCAGCGGTAGCAAAAGGAATCAATTTAGCAGACTATGACCAATTTGATCAATACGATCAAGATGGTGATG
GAAATAAAAATGAGCCAGATGGCATTATTGATCATTTAATGGTTGTACATGCTGGCGTTGGTCAAGAAGCTGGCGGCGGT
AAATTGAAAGATGATGCGATTTGGTCACATCGTTCAAAACTAGGTTCAAAACCATATGCAATTGATGGCACGAAATCTTC
TGTTTCGAACTGGGGCGGAAAGATGGCTGCATATGATTATACAATCGAGCCTGAAGACGGGGCAGTTGGTGTGTTTGCAC
ATGAGTATGGCCATGATTTAGGCTTACCAGATGAATATGATACAAAGTACTCAGGACAAGGTGAACCTGTTGAGTCATGG
TCTATTATGAGTGGTGGTAGCTGGGCTGGAAAAATTGCAGGAACAGAGCCAACGAGTTTCTCACCACAAAATAAAGAGTT
TTTCCAAAAGAATATGAAGGGGAACTGGGCGAATATCCTTGAAGTAGATTATGACAAACTTAGCAAAGGAATCGGTGTTG
CGACATATGTAGATCAAAGTACTACAAAATCTAAACGACCTGGAATCGTTCGTGTTAACTTGCCAGACAAAGATATAAAA
AATATCGAATCAGCGTTTGGTAAGAAGTTCTATTACAGTACAAAAGGAAATGACATTCATACAACACTTGAGACACCAGT
ATTTGACTTAACAAATGCAAAGGATGCTAAGTTCGATTATAAGGCATTTTACGAACTTGAAGCGAAGTATGATTTCCTTG
ACGTATATGCGATTGCAGAAGATGGAACGAAGACACGCATTGATAGAATGGGCGAAAAAGATGTAAAAGGCGGCGCGGAT
ACAACTGATGGTAAGTGGGTTGATAAATCATACGATTTAAGCCAATTCAAAGGAAAAAAAGTAAAACTGCAATTTGAGTA
CTTAACAGATATTGCAGTAGCTTATAAAGGGTTTGCGTTAGATAATGCAGCATTAACTGTAGATGGAAAAGTTGTTTTCT
CTGATGATGCAGAAGGTCAGCCAGCAATGACGTTAAAAGGCTTTACTGTGTCTAACGGATTTGAACAGAAAAAACATAAT
TACTATGTAGAGTGGAGAAATTACGCTGGTTCTGACACTGCGTTACAACATGCACGTGGCCCAGTATTTAATACAGGAAT
GGTTGTATGGTATGCGGATCAAAGCTTTACAGATAACTGGGTAGGCGTTCATCCAGGTGAAGGGTTCTTAGGAGTAGTAG
ATTCTCATCCAGAGGCAATTGTAGGGACATTAAACGGACAACCTACTGTGAAGAGCAGTACGCGTTACCAAATTGCCGAT
GCGGCATTCTCATTTGATCAAACACCAGCATGGAAAGTAAATTCACCAACTCGCGGTATCTTCGATTATAAAGGATTACC
AGGAGTGGCAAAATTTGATGATTCTAAGCAATACATCAACAGTATTATTCCTGATGCAGGACGTAAGTTACCGAAACTAG
GACTGAAGTTTGAAGTGGTAGGCCAAGCTGAAGACAAGTCTGCAGGTGCAGTGTGGCTTCATCGATAA

Upstream 100 bases:

>100_bases
CATTTTATTTGTTGAAAAAGATTGAATATTCGTATTATAACGAATATTATGTTGTTATCGGCAAAAAACGATAATTTGCA
GACACTGGGGAGGAAATACA

Downstream 100 bases:

>100_bases
AATAAGGTAAAACGAAGAGGAGCTGCGATAAGTCGGTGAAACTGACTTATCGCAGCTTTTTTCTTCTTGTGAAAAAACTT
GCTGTTTTTTTTATGTACTT

Product: immune inhibitor A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 795; Mature: 795

Protein sequence:

>795_residues
MKKKKKLKPLAVLTTAAVLSSTFAFGGHAAYAETPTSSLPIDEHLIPEERLAEALKQRGVIDQSASQAETSKAVEKYVEK
KKGENPGKEILTGDSLTQEASDFMKKVKDAKMKENEQAQQPEVGPVAGQGAALNPGKLNGKVPTTSAKQEEYNGAVRKDK
VLVLLVEFSDFKHNNIDQEPGYMYSKDFNREHYQKMLFGDEPFTLFDGSKINTFKQYYEEQSGGSYTVDGTVTEWLTVPG
KASDYGADAGTGHDNKGPLGPKDFVKEALKAAVAKGINLADYDQFDQYDQDGDGNKNEPDGIIDHLMVVHAGVGQEAGGG
KLKDDAIWSHRSKLGSKPYAIDGTKSSVSNWGGKMAAYDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGQGEPVESW
SIMSGGSWAGKIAGTEPTSFSPQNKEFFQKNMKGNWANILEVDYDKLSKGIGVATYVDQSTTKSKRPGIVRVNLPDKDIK
NIESAFGKKFYYSTKGNDIHTTLETPVFDLTNAKDAKFDYKAFYELEAKYDFLDVYAIAEDGTKTRIDRMGEKDVKGGAD
TTDGKWVDKSYDLSQFKGKKVKLQFEYLTDIAVAYKGFALDNAALTVDGKVVFSDDAEGQPAMTLKGFTVSNGFEQKKHN
YYVEWRNYAGSDTALQHARGPVFNTGMVVWYADQSFTDNWVGVHPGEGFLGVVDSHPEAIVGTLNGQPTVKSSTRYQIAD
AAFSFDQTPAWKVNSPTRGIFDYKGLPGVAKFDDSKQYINSIIPDAGRKLPKLGLKFEVVGQAEDKSAGAVWLHR

Sequences:

>Translated_795_residues
MKKKKKLKPLAVLTTAAVLSSTFAFGGHAAYAETPTSSLPIDEHLIPEERLAEALKQRGVIDQSASQAETSKAVEKYVEK
KKGENPGKEILTGDSLTQEASDFMKKVKDAKMKENEQAQQPEVGPVAGQGAALNPGKLNGKVPTTSAKQEEYNGAVRKDK
VLVLLVEFSDFKHNNIDQEPGYMYSKDFNREHYQKMLFGDEPFTLFDGSKINTFKQYYEEQSGGSYTVDGTVTEWLTVPG
KASDYGADAGTGHDNKGPLGPKDFVKEALKAAVAKGINLADYDQFDQYDQDGDGNKNEPDGIIDHLMVVHAGVGQEAGGG
KLKDDAIWSHRSKLGSKPYAIDGTKSSVSNWGGKMAAYDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGQGEPVESW
SIMSGGSWAGKIAGTEPTSFSPQNKEFFQKNMKGNWANILEVDYDKLSKGIGVATYVDQSTTKSKRPGIVRVNLPDKDIK
NIESAFGKKFYYSTKGNDIHTTLETPVFDLTNAKDAKFDYKAFYELEAKYDFLDVYAIAEDGTKTRIDRMGEKDVKGGAD
TTDGKWVDKSYDLSQFKGKKVKLQFEYLTDIAVAYKGFALDNAALTVDGKVVFSDDAEGQPAMTLKGFTVSNGFEQKKHN
YYVEWRNYAGSDTALQHARGPVFNTGMVVWYADQSFTDNWVGVHPGEGFLGVVDSHPEAIVGTLNGQPTVKSSTRYQIAD
AAFSFDQTPAWKVNSPTRGIFDYKGLPGVAKFDDSKQYINSIIPDAGRKLPKLGLKFEVVGQAEDKSAGAVWLHR
>Mature_795_residues
MKKKKKLKPLAVLTTAAVLSSTFAFGGHAAYAETPTSSLPIDEHLIPEERLAEALKQRGVIDQSASQAETSKAVEKYVEK
KKGENPGKEILTGDSLTQEASDFMKKVKDAKMKENEQAQQPEVGPVAGQGAALNPGKLNGKVPTTSAKQEEYNGAVRKDK
VLVLLVEFSDFKHNNIDQEPGYMYSKDFNREHYQKMLFGDEPFTLFDGSKINTFKQYYEEQSGGSYTVDGTVTEWLTVPG
KASDYGADAGTGHDNKGPLGPKDFVKEALKAAVAKGINLADYDQFDQYDQDGDGNKNEPDGIIDHLMVVHAGVGQEAGGG
KLKDDAIWSHRSKLGSKPYAIDGTKSSVSNWGGKMAAYDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGQGEPVESW
SIMSGGSWAGKIAGTEPTSFSPQNKEFFQKNMKGNWANILEVDYDKLSKGIGVATYVDQSTTKSKRPGIVRVNLPDKDIK
NIESAFGKKFYYSTKGNDIHTTLETPVFDLTNAKDAKFDYKAFYELEAKYDFLDVYAIAEDGTKTRIDRMGEKDVKGGAD
TTDGKWVDKSYDLSQFKGKKVKLQFEYLTDIAVAYKGFALDNAALTVDGKVVFSDDAEGQPAMTLKGFTVSNGFEQKKHN
YYVEWRNYAGSDTALQHARGPVFNTGMVVWYADQSFTDNWVGVHPGEGFLGVVDSHPEAIVGTLNGQPTVKSSTRYQIAD
AAFSFDQTPAWKVNSPTRGIFDYKGLPGVAKFDDSKQYINSIIPDAGRKLPKLGLKFEVVGQAEDKSAGAVWLHR

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: COG4412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 87261; Mature: 87261

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKKKLKPLAVLTTAAVLSSTFAFGGHAAYAETPTSSLPIDEHLIPEERLAEALKQRGV
CCCCHHCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHCCCHHHHHHHHHHCCC
IDQSASQAETSKAVEKYVEKKKGENPGKEILTGDSLTQEASDFMKKVKDAKMKENEQAQQ
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHCCCHHHCC
PEVGPVAGQGAALNPGKLNGKVPTTSAKQEEYNGAVRKDKVLVLLVEFSDFKHNNIDQEP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCC
GYMYSKDFNREHYQKMLFGDEPFTLFDGSKINTFKQYYEEQSGGSYTVDGTVTEWLTVPG
CEEECCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCEEECCCEEEEEECCC
KASDYGADAGTGHDNKGPLGPKDFVKEALKAAVAKGINLADYDQFDQYDQDGDGNKNEPD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCH
GIIDHLMVVHAGVGQEAGGGKLKDDAIWSHRSKLGSKPYAIDGTKSSVSNWGGKMAAYDY
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHCCCCEEEEEE
TIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGQGEPVESWSIMSGGSWAGKIAGTEPTSF
EECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCC
SPQNKEFFQKNMKGNWANILEVDYDKLSKGIGVATYVDQSTTKSKRPGIVRVNLPDKDIK
CCCCHHHHHHHCCCCCCEEEEECHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCHHHH
NIESAFGKKFYYSTKGNDIHTTLETPVFDLTNAKDAKFDYKAFYELEAKYDFLDVYAIAE
HHHHHHCCEEEEECCCCEEEEEECCCEEECCCCCCCCCCEEEEEEEECCCCEEEEEEEEC
DGTKTRIDRMGEKDVKGGADTTDGKWVDKSYDLSQFKGKKVKLQFEYLTDIAVAYKGFAL
CCCHHHHHHCCCHHCCCCCCCCCCCEECCCCCHHHCCCCEEEEEHHHHHHHHHHHHCEEE
DNAALTVDGKVVFSDDAEGQPAMTLKGFTVSNGFEQKKHNYYVEWRNYAGSDTALQHARG
CCEEEEECCEEEECCCCCCCCCEEEECEEECCCCHHCCCCEEEEECCCCCCHHHHHHHCC
PVFNTGMVVWYADQSFTDNWVGVHPGEGFLGVVDSHPEAIVGTLNGQPTVKSSTRYQIAD
CEEECCEEEEEECCCCCCCCCEECCCCCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEH
AAFSFDQTPAWKVNSPTRGIFDYKGLPGVAKFDDSKQYINSIIPDAGRKLPKLGLKFEVV
HHHCCCCCCCEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCCCCCCHHCCCEEEEE
GQAEDKSAGAVWLHR
ECCCCCCCCEEEEEC
>Mature Secondary Structure
MKKKKKLKPLAVLTTAAVLSSTFAFGGHAAYAETPTSSLPIDEHLIPEERLAEALKQRGV
CCCCHHCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHCCCHHHHHHHHHHCCC
IDQSASQAETSKAVEKYVEKKKGENPGKEILTGDSLTQEASDFMKKVKDAKMKENEQAQQ
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHCCCHHHCC
PEVGPVAGQGAALNPGKLNGKVPTTSAKQEEYNGAVRKDKVLVLLVEFSDFKHNNIDQEP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCC
GYMYSKDFNREHYQKMLFGDEPFTLFDGSKINTFKQYYEEQSGGSYTVDGTVTEWLTVPG
CEEECCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCEEECCCEEEEEECCC
KASDYGADAGTGHDNKGPLGPKDFVKEALKAAVAKGINLADYDQFDQYDQDGDGNKNEPD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCH
GIIDHLMVVHAGVGQEAGGGKLKDDAIWSHRSKLGSKPYAIDGTKSSVSNWGGKMAAYDY
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHCCCCEEEEEE
TIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGQGEPVESWSIMSGGSWAGKIAGTEPTSF
EECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCC
SPQNKEFFQKNMKGNWANILEVDYDKLSKGIGVATYVDQSTTKSKRPGIVRVNLPDKDIK
CCCCHHHHHHHCCCCCCEEEEECHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCHHHH
NIESAFGKKFYYSTKGNDIHTTLETPVFDLTNAKDAKFDYKAFYELEAKYDFLDVYAIAE
HHHHHHCCEEEEECCCCEEEEEECCCEEECCCCCCCCCCEEEEEEEECCCCEEEEEEEEC
DGTKTRIDRMGEKDVKGGADTTDGKWVDKSYDLSQFKGKKVKLQFEYLTDIAVAYKGFAL
CCCHHHHHHCCCHHCCCCCCCCCCCEECCCCCHHHCCCCEEEEEHHHHHHHHHHHHCEEE
DNAALTVDGKVVFSDDAEGQPAMTLKGFTVSNGFEQKKHNYYVEWRNYAGSDTALQHARG
CCEEEEECCEEEECCCCCCCCCEEEECEEECCCCHHCCCCEEEEECCCCCCHHHHHHHCC
PVFNTGMVVWYADQSFTDNWVGVHPGEGFLGVVDSHPEAIVGTLNGQPTVKSSTRYQIAD
CEEECCEEEEEECCCCCCCCCEECCCCCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEH
AAFSFDQTPAWKVNSPTRGIFDYKGLPGVAKFDDSKQYINSIIPDAGRKLPKLGLKFEVV
HHHCCCCCCCEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCCCCCCHHCCCEEEEE
GQAEDKSAGAVWLHR
ECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]