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The map label for this gene is engA

Identifier: 21672838

GI number: 21672838

Start: 639041

End: 640402

Strand: Reverse

Name: engA

Synonym: BUsg582

Alternate gene names: 21672838

Gene position: 640402-639041 (Counterclockwise)

Preceding gene: 21672839

Following gene: 21672832

Centisome position: 99.84

GC content: 22.69

Gene sequence:

>1362_bases
ATGTTACCTATAATCGTATTAATTGGACGCACTAATGTAGGAAAATCTACTTTATTTAATATATTAAGTAAAACAAGAAA
TGCATTAGTTGCTGATTATCCCGGACTTACTAGAGACAGAAATTATGGATATTGTTACTTAAAAGAAAATAAAAAAATAA
CTATAGTAGATACAGCAGGAATCAATTTTAAATCACAAAAAATAGAAAAACAAAGTCATGAACAAACCTTAAAAGCAATT
AAAGAATGCGACGGAATTTTATTTTTAGTAAATGCTCGTGATGGAGTTATGCCAGAGGAATATGAAATTTCTCGAAAAAT
AAGAAAATATGAAAAAAAAACAATATTAGTAATTAACAAAATAGATGGAATTAAAGAAATTTCTAAAATTAATGAATTTT
ATTCTTTAGGATTTAAAGAAAATATAAAAATTTCTGCAAGTCATAACCAAGGAATTAATAATCTTATTTCAAAATATTTA
ACTCCTTGGATTAACTCAAAATTTAAAGAAAAAAAACTAGAAAAAATAAGTCAAGAGCATTCTAAAAAAGAAAAAAATTC
AGTAAAAATAGCATGTATAGGAAAACCAAATGTTGGAAAATCAACATTAATTAATTCACTACTAATGAAAAAAAGAATGA
TTACTTCAAACAAAGCCGGTACAACGTTAGATACTGTATTAGTACCTATTAAATATAATTATAAAAATTATATTTTTATA
GATACAGCAGGAATGTCTAAGAAAAAATCTAAAACAAATAAAATAGAAAAATTTTGCAAAATTAAAACTTTACAAACAAT
TGAAAAATCTCATTTAACTTTACTCATAATAGATGCAAAAGATCAAATATCTAAACAAGATTTGTTATTATCTAGTTTTA
TTGAAAAATCTGGAAAACCATTAATTATCGTAATTAACAAATGTGATTTATTAAGTTTAAAAGAAAAAAAAAATTTAGAA
AACTTAATCAAAAAACAATTAAAATGTAACTTTTTTTCAAAAATACATTTTATATCAGCACTGAATAATGAGGGAACAGT
AGAATTATTTAAATCTATTGATACCTCTTATCATACTTCTCAAAAGAAAATAAAAACCTCTCAAGTTATGAAAATAATGC
ATAAAGCAGTAAAAAAACATCAACCTCCAATTATAAATGGAAGACGAATAAAGCTAAAATATGCACATCTAGGAAATTCT
AATCCAATCGAGATAATGATACATGGTAATCAAGTAAAAAATTTATCTTTATGCTATAAAAAATATTTAAAAAATTTCTT
TTACAAAACGCTAAAAATGAATGGAACACCAATAAAAATACAATTTAAAGAAACTATGAATCCATATATCTCAAAAAAAT
AA

Upstream 100 bases:

>100_bases
TACCTTGAAAAATCTAATGCATCTAAAGAAATTATTAACATGAAAATTAACGAAATAAAAAGATAAATGCAAAAATTAAA
ATAAAAATGGATATCTTATT

Downstream 100 bases:

>100_bases
TTAATTTTCTATTATATAGTTAGTATTATATAAGGGAATTTGTACTTCTATATCAATATTTCCAATAATTGCTTGACAAC
TCAAACGACTTGTAGACTCT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MLPIIVLIGRTNVGKSTLFNILSKTRNALVADYPGLTRDRNYGYCYLKENKKITIVDTAGINFKSQKIEKQSHEQTLKAI
KECDGILFLVNARDGVMPEEYEISRKIRKYEKKTILVINKIDGIKEISKINEFYSLGFKENIKISASHNQGINNLISKYL
TPWINSKFKEKKLEKISQEHSKKEKNSVKIACIGKPNVGKSTLINSLLMKKRMITSNKAGTTLDTVLVPIKYNYKNYIFI
DTAGMSKKKSKTNKIEKFCKIKTLQTIEKSHLTLLIIDAKDQISKQDLLLSSFIEKSGKPLIIVINKCDLLSLKEKKNLE
NLIKKQLKCNFFSKIHFISALNNEGTVELFKSIDTSYHTSQKKIKTSQVMKIMHKAVKKHQPPIINGRRIKLKYAHLGNS
NPIEIMIHGNQVKNLSLCYKKYLKNFFYKTLKMNGTPIKIQFKETMNPYISKK

Sequences:

>Translated_453_residues
MLPIIVLIGRTNVGKSTLFNILSKTRNALVADYPGLTRDRNYGYCYLKENKKITIVDTAGINFKSQKIEKQSHEQTLKAI
KECDGILFLVNARDGVMPEEYEISRKIRKYEKKTILVINKIDGIKEISKINEFYSLGFKENIKISASHNQGINNLISKYL
TPWINSKFKEKKLEKISQEHSKKEKNSVKIACIGKPNVGKSTLINSLLMKKRMITSNKAGTTLDTVLVPIKYNYKNYIFI
DTAGMSKKKSKTNKIEKFCKIKTLQTIEKSHLTLLIIDAKDQISKQDLLLSSFIEKSGKPLIIVINKCDLLSLKEKKNLE
NLIKKQLKCNFFSKIHFISALNNEGTVELFKSIDTSYHTSQKKIKTSQVMKIMHKAVKKHQPPIINGRRIKLKYAHLGNS
NPIEIMIHGNQVKNLSLCYKKYLKNFFYKTLKMNGTPIKIQFKETMNPYISKK
>Mature_453_residues
MLPIIVLIGRTNVGKSTLFNILSKTRNALVADYPGLTRDRNYGYCYLKENKKITIVDTAGINFKSQKIEKQSHEQTLKAI
KECDGILFLVNARDGVMPEEYEISRKIRKYEKKTILVINKIDGIKEISKINEFYSLGFKENIKISASHNQGINNLISKYL
TPWINSKFKEKKLEKISQEHSKKEKNSVKIACIGKPNVGKSTLINSLLMKKRMITSNKAGTTLDTVLVPIKYNYKNYIFI
DTAGMSKKKSKTNKIEKFCKIKTLQTIEKSHLTLLIIDAKDQISKQDLLLSSFIEKSGKPLIIVINKCDLLSLKEKKNLE
NLIKKQLKCNFFSKIHFISALNNEGTVELFKSIDTSYHTSQKKIKTSQVMKIMHKAVKKHQPPIINGRRIKLKYAHLGNS
NPIEIMIHGNQVKNLSLCYKKYLKNFFYKTLKMNGTPIKIQFKETMNPYISKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=469, Percent_Identity=43.0703624733475, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI2367268, Length=154, Percent_Identity=31.1688311688312, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=196, Percent_Identity=32.1428571428571, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45550813, Length=161, Percent_Identity=31.055900621118, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_BUCAP (O51881)

Other databases:

- EMBL:   AF008210
- EMBL:   AE013218
- RefSeq:   NP_660905.1
- ProteinModelPortal:   O51881
- EnsemblBacteria:   EBBUCT00000000250
- GeneID:   1005618
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg582
- GeneTree:   EBGT00050000007774
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   BAPH198804:BUSG582-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 52048; Mature: 52048

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPIIVLIGRTNVGKSTLFNILSKTRNALVADYPGLTRDRNYGYCYLKENKKITIVDTAG
CCEEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEECCCEEEEEEECC
INFKSQKIEKQSHEQTLKAIKECDGILFLVNARDGVMPEEYEISRKIRKYEKKTILVINK
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEC
IDGIKEISKINEFYSLGFKENIKISASHNQGINNLISKYLTPWINSKFKEKKLEKISQEH
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SKKEKNSVKIACIGKPNVGKSTLINSLLMKKRMITSNKAGTTLDTVLVPIKYNYKNYIFI
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCEEEEE
DTAGMSKKKSKTNKIEKFCKIKTLQTIEKSHLTLLIIDAKDQISKQDLLLSSFIEKSGKP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHCCHHHHHHHHHHHHCCCE
LIIVINKCDLLSLKEKKNLENLIKKQLKCNFFSKIHFISALNNEGTVELFKSIDTSYHTS
EEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCH
QKKIKTSQVMKIMHKAVKKHQPPIINGRRIKLKYAHLGNSNPIEIMIHGNQVKNLSLCYK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHHHHH
KYLKNFFYKTLKMNGTPIKIQFKETMNPYISKK
HHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCC
>Mature Secondary Structure
MLPIIVLIGRTNVGKSTLFNILSKTRNALVADYPGLTRDRNYGYCYLKENKKITIVDTAG
CCEEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEECCCEEEEEEECC
INFKSQKIEKQSHEQTLKAIKECDGILFLVNARDGVMPEEYEISRKIRKYEKKTILVINK
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEC
IDGIKEISKINEFYSLGFKENIKISASHNQGINNLISKYLTPWINSKFKEKKLEKISQEH
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SKKEKNSVKIACIGKPNVGKSTLINSLLMKKRMITSNKAGTTLDTVLVPIKYNYKNYIFI
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCEEEEE
DTAGMSKKKSKTNKIEKFCKIKTLQTIEKSHLTLLIIDAKDQISKQDLLLSSFIEKSGKP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHCCHHHHHHHHHHHHCCCE
LIIVINKCDLLSLKEKKNLENLIKKQLKCNFFSKIHFISALNNEGTVELFKSIDTSYHTS
EEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCH
QKKIKTSQVMKIMHKAVKKHQPPIINGRRIKLKYAHLGNSNPIEIMIHGNQVKNLSLCYK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHHHHH
KYLKNFFYKTLKMNGTPIKIQFKETMNPYISKK
HHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9516544; 12089438