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The map label for this gene is rnr

Identifier: 21672806

GI number: 21672806

Start: 596477

End: 598657

Strand: Reverse

Name: rnr

Synonym: BUsg545

Alternate gene names: 21672806

Gene position: 598657-596477 (Counterclockwise)

Preceding gene: 21672807

Following gene: 21672805

Centisome position: 93.33

GC content: 27.56

Gene sequence:

>2181_bases
ATGGTAGTAGATTCCTACCAAAAAAAAGAGACTAAGAAATATAGAAATTTTATCCCACGTCGAGAACAAATTTTATTTTT
GTTAAAAACTGATAAAGACCTAATAAGTCAAAAAAAATTAGAAAAAAAATTTAGTATCAATAGTCAAGAACAAAAAAAAG
CACTACGTCGGAGATTAAGAGCAATGGAACGAGATGGTCAAATTATATACACTCGAAATCGTTGTTATATTACTCCAGAA
AATTTAAAAATAGTTACAGGTAAAGTTATAGGTCACAGAGATGGCTATGGTTTTCTTAGAACAGAAACATTTAAAGATGA
TCTCTGGCTTTCAATAGAACAAATGAAATTATGTATTCATGGTGATGTTATTTTAGCACATATTGTCAAATCTGATAGAA
AAGGAAGAAATTCGGCAAAAGTATTAAAAATATTGCGACCAAATGATGTTTTGATTGTAGGTCGATATTGCGTCGATAAT
AAAAAAAAATTTGTTATCCCAAACGATACTCGATTTAATTTTAAAATATTTATTTTAGATTCACTTATTTCTAATGAAAA
TATTTCTATAGGAACAATTGTGGTAGTAAAATTACGAGAAAATGCCACGAAAAAAAGTAAGATACAAGGAACTATAGTAG
AAGTTCTTGGAAAAGAAATGGGAACAAATTTAGCTATAAAAATAGCATTACGTACTCATTGTATCCCCTATTTATGGTCA
AAAGAAGTTGAATACCAATTATGTGGAATAAAGAGTAAAATCAATGAAAAAGATTTTAAAAATCGTATAGATTTAAGACA
TCTCCCATTTTTTACAATTGATGAAGAAGATGCTCGTGATTTTGACGATGCTATTTTTTGTAAAAAAAAAACTAATGGAG
AAAAAGGATGGAAACTATGGGTAGCAATTTCTGATGTAAGTTACTATATCCAGCCTGATACTGCTTTAGACAAAGCTGCT
TCAAAAAGAGGTACATCTATTTATTTTCCCTCTTTAGTTATACCTATGTTACCAGAAAAAATATCTATAGATGTGTGCTC
TTTAAATCCAAATGCAGAACGTTTATCTTTAATATGCGAAATGAATTTATCAAATAAAGGAGAATTAATCACATATAAAC
ATTATGAAGCAGTCATATGTTCTCATGGACGTTTTACATATAATGAAATATTTAAAATTTGGAATGGCGATATTGAACTT
TGTTTTAAATATAAAAAATTATTAAAATACATTCAAAATTTATCGTCTTTACAAAAAATTTTAAAGAAATACAATGTTTC
TAAAAGAGGTATTTATTTTGAAAATATAGAAGCTAAATTTATATTAGATTCTAATTATCGAATTAAAAATATTTCCCAAA
ACATTCGAAATGATGCGCATAAATTTATTGAATCATGTATGATATTAGCGAATATAGCTTCAGCTGAATTTGTTAAAAAG
CATAAGTCTCCAGTTTTGTTTCGCAATCATGATCGTCCTGATAAAGATAGTATTATTAATTTTCGATCAGTTTTAAAAAA
ATTAGGATTGTCTTTGTTAGGAGGAGAAATACCAGAATCTACGGATTATTCAGAATTATTAAAAAAAATTTCTACTCGCC
CTGATTATGAAATGATTCAAACTATATTATTGCGTTCTATGAAACAAGCTGTATACTCTCCAGATAATCGTGGCCACTTT
GGTTTATCTTTATCAAGCTATGTTCACTTTACTTCTCCTATTAGGCGCTATCCTGATCTTTTAGTTCACAGAGTTATTAA
AAACTTACTATTAAAAGAAAAAAATCTATCTAAATATCATTTATATAATCTTAATGAAGTAACAAAAATAGGTCTTCATT
GTTCAATGACAGAAAGACGTGCAGATGAAGCTACTAGAGATGTATTAGATTGGTTAAAATGCGATTTTATGCAAAAAAAA
ATAGGAGACGTATTAACAGGAGTTATTTCTAATGTTACTTCGTTTGGTTTTTTTGTGCGTTTAAATCAATTTTTCATTGA
TGGATTAGTGCATATAGCAACTTTAATTGATGATTACTATTATTTTGATTCTATTGGATTAAAACTTATTGGTAAGTCAA
GTAAAAATACTTATTGTCTTGGTGATACCTTAAAAGTAAAGGTTATTTCTGTTAATTTAAATGAGCGTAAGATAGAATTA
TCCCTATATATGTCTCGTTGA

Upstream 100 bases:

>100_bases
AAAAAATAAGATTTTTAAATAAATTTGACGATTATTAATTGATGATAAATTATTTTTAATAAAACATATATTATAGAATA
ATATAATTGGAGAAGTAAAT

Downstream 100 bases:

>100_bases
TTTTTAATTTAGAAAGAATATTTTTTTAAAAATGAAATTTTATTGATTTTTTTTTTAAATTAAAATACCATATATATAAT
TAGCTATAATCTTTTTACAA

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog

Number of amino acids: Translated: 726; Mature: 726

Protein sequence:

>726_residues
MVVDSYQKKETKKYRNFIPRREQILFLLKTDKDLISQKKLEKKFSINSQEQKKALRRRLRAMERDGQIIYTRNRCYITPE
NLKIVTGKVIGHRDGYGFLRTETFKDDLWLSIEQMKLCIHGDVILAHIVKSDRKGRNSAKVLKILRPNDVLIVGRYCVDN
KKKFVIPNDTRFNFKIFILDSLISNENISIGTIVVVKLRENATKKSKIQGTIVEVLGKEMGTNLAIKIALRTHCIPYLWS
KEVEYQLCGIKSKINEKDFKNRIDLRHLPFFTIDEEDARDFDDAIFCKKKTNGEKGWKLWVAISDVSYYIQPDTALDKAA
SKRGTSIYFPSLVIPMLPEKISIDVCSLNPNAERLSLICEMNLSNKGELITYKHYEAVICSHGRFTYNEIFKIWNGDIEL
CFKYKKLLKYIQNLSSLQKILKKYNVSKRGIYFENIEAKFILDSNYRIKNISQNIRNDAHKFIESCMILANIASAEFVKK
HKSPVLFRNHDRPDKDSIINFRSVLKKLGLSLLGGEIPESTDYSELLKKISTRPDYEMIQTILLRSMKQAVYSPDNRGHF
GLSLSSYVHFTSPIRRYPDLLVHRVIKNLLLKEKNLSKYHLYNLNEVTKIGLHCSMTERRADEATRDVLDWLKCDFMQKK
IGDVLTGVISNVTSFGFFVRLNQFFIDGLVHIATLIDDYYYFDSIGLKLIGKSSKNTYCLGDTLKVKVISVNLNERKIEL
SLYMSR

Sequences:

>Translated_726_residues
MVVDSYQKKETKKYRNFIPRREQILFLLKTDKDLISQKKLEKKFSINSQEQKKALRRRLRAMERDGQIIYTRNRCYITPE
NLKIVTGKVIGHRDGYGFLRTETFKDDLWLSIEQMKLCIHGDVILAHIVKSDRKGRNSAKVLKILRPNDVLIVGRYCVDN
KKKFVIPNDTRFNFKIFILDSLISNENISIGTIVVVKLRENATKKSKIQGTIVEVLGKEMGTNLAIKIALRTHCIPYLWS
KEVEYQLCGIKSKINEKDFKNRIDLRHLPFFTIDEEDARDFDDAIFCKKKTNGEKGWKLWVAISDVSYYIQPDTALDKAA
SKRGTSIYFPSLVIPMLPEKISIDVCSLNPNAERLSLICEMNLSNKGELITYKHYEAVICSHGRFTYNEIFKIWNGDIEL
CFKYKKLLKYIQNLSSLQKILKKYNVSKRGIYFENIEAKFILDSNYRIKNISQNIRNDAHKFIESCMILANIASAEFVKK
HKSPVLFRNHDRPDKDSIINFRSVLKKLGLSLLGGEIPESTDYSELLKKISTRPDYEMIQTILLRSMKQAVYSPDNRGHF
GLSLSSYVHFTSPIRRYPDLLVHRVIKNLLLKEKNLSKYHLYNLNEVTKIGLHCSMTERRADEATRDVLDWLKCDFMQKK
IGDVLTGVISNVTSFGFFVRLNQFFIDGLVHIATLIDDYYYFDSIGLKLIGKSSKNTYCLGDTLKVKVISVNLNERKIEL
SLYMSR
>Mature_726_residues
MVVDSYQKKETKKYRNFIPRREQILFLLKTDKDLISQKKLEKKFSINSQEQKKALRRRLRAMERDGQIIYTRNRCYITPE
NLKIVTGKVIGHRDGYGFLRTETFKDDLWLSIEQMKLCIHGDVILAHIVKSDRKGRNSAKVLKILRPNDVLIVGRYCVDN
KKKFVIPNDTRFNFKIFILDSLISNENISIGTIVVVKLRENATKKSKIQGTIVEVLGKEMGTNLAIKIALRTHCIPYLWS
KEVEYQLCGIKSKINEKDFKNRIDLRHLPFFTIDEEDARDFDDAIFCKKKTNGEKGWKLWVAISDVSYYIQPDTALDKAA
SKRGTSIYFPSLVIPMLPEKISIDVCSLNPNAERLSLICEMNLSNKGELITYKHYEAVICSHGRFTYNEIFKIWNGDIEL
CFKYKKLLKYIQNLSSLQKILKKYNVSKRGIYFENIEAKFILDSNYRIKNISQNIRNDAHKFIESCMILANIASAEFVKK
HKSPVLFRNHDRPDKDSIINFRSVLKKLGLSLLGGEIPESTDYSELLKKISTRPDYEMIQTILLRSMKQAVYSPDNRGHF
GLSLSSYVHFTSPIRRYPDLLVHRVIKNLLLKEKNLSKYHLYNLNEVTKIGLHCSMTERRADEATRDVLDWLKCDFMQKK
IGDVLTGVISNVTSFGFFVRLNQFFIDGLVHIATLIDDYYYFDSIGLKLIGKSSKNTYCLGDTLKVKVISVNLNERKIEL
SLYMSR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain

Homologues:

Organism=Homo sapiens, GI190014623, Length=390, Percent_Identity=31.5384615384615, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI190014625, Length=390, Percent_Identity=31.5384615384615, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI134288890, Length=371, Percent_Identity=27.2237196765499, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI219521928, Length=633, Percent_Identity=23.2227488151659, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI19115966, Length=633, Percent_Identity=23.2227488151659, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI87082383, Length=732, Percent_Identity=54.9180327868852, Blast_Score=851, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=588, Percent_Identity=25.6802721088435, Blast_Score=163, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17553506, Length=405, Percent_Identity=29.6296296296296, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI212645896, Length=424, Percent_Identity=26.1792452830189, Blast_Score=150, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6324552, Length=492, Percent_Identity=28.4552845528455, Blast_Score=134, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24649634, Length=390, Percent_Identity=31.025641025641, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24654592, Length=377, Percent_Identity=29.7082228116711, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI19922976, Length=377, Percent_Identity=29.7082228116711, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24654597, Length=377, Percent_Identity=29.7082228116711, Blast_Score=139, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNR_BUCAP (Q8K917)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660873.1
- ProteinModelPortal:   Q8K917
- SMR:   Q8K917
- EnsemblBacteria:   EBBUCT00000000390
- GeneID:   1005642
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg545
- GeneTree:   EBGT00050000007716
- HOGENOM:   HBG690243
- OMA:   GHRDGFG
- ProtClustDB:   CLSK315844
- BioCyc:   BAPH198804:BUSG545-MONOMER
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR23355:SF9
- SMART:   SM00357
- SMART:   SM00955
- SMART:   SM00316
- TIGRFAMs:   TIGR00358
- TIGRFAMs:   TIGR02063

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1; SSF50249 Nucleic_acid_OB

EC number: 3.1.-.- [C]

Molecular weight: Translated: 84329; Mature: 84329

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS01175 RIBONUCLEASE_II; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVDSYQKKETKKYRNFIPRREQILFLLKTDKDLISQKKLEKKFSINSQEQKKALRRRLR
CCCCCHHHHHHHHHHHHCCCCHHEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AMERDGQIIYTRNRCYITPENLKIVTGKVIGHRDGYGFLRTETFKDDLWLSIEQMKLCIH
HHCCCCCEEEECCEEEECCCCCEEEEEEEEECCCCCCCEEECCCCCCCEEEHHHHEEHHC
GDVILAHIVKSDRKGRNSAKVLKILRPNDVLIVGRYCVDNKKKFVIPNDTRFNFKIFILD
CHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEEEECCCCEEECCCCCCEEEEEEEEE
SLISNENISIGTIVVVKLRENATKKSKIQGTIVEVLGKEMGTNLAIKIALRTHCIPYLWS
HHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHCCHHHHHC
KEVEYQLCGIKSKINEKDFKNRIDLRHLPFFTIDEEDARDFDDAIFCKKKTNGEKGWKLW
CCCCEEEECCHHHCCHHHHHHCCCCEECCEEEECCHHCCCCCCCEEEECCCCCCCCEEEE
VAISDVSYYIQPDTALDKAASKRGTSIYFPSLVIPMLPEKISIDVCSLNPNAERLSLICE
EEEECEEEEECCCHHHHHHHHCCCCEEEECHHHHHCCCCCEEEEEEECCCCHHHEEEEEE
MNLSNKGELITYKHYEAVICSHGRFTYNEIFKIWNGDIELCFKYKKLLKYIQNLSSLQKI
ECCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LKKYNVSKRGIYFENIEAKFILDSNYRIKNISQNIRNDAHKFIESCMILANIASAEFVKK
HHHCCCCCCCEEEECCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKSPVLFRNHDRPDKDSIINFRSVLKKLGLSLLGGEIPESTDYSELLKKISTRPDYEMIQ
CCCCCEECCCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHH
TILLRSMKQAVYSPDNRGHFGLSLSSYVHFTSPIRRYPDLLVHRVIKNLLLKEKNLSKYH
HHHHHHHHHHHCCCCCCCEECEEHHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LYNLNEVTKIGLHCSMTERRADEATRDVLDWLKCDFMQKKIGDVLTGVISNVTSFGFFVR
EECCCHHHEECEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNQFFIDGLVHIATLIDDYYYFDSIGLKLIGKSSKNTYCLGDTLKVKVISVNLNERKIEL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCEEEEEEEEEECCCEEEEE
SLYMSR
EEEECC
>Mature Secondary Structure
MVVDSYQKKETKKYRNFIPRREQILFLLKTDKDLISQKKLEKKFSINSQEQKKALRRRLR
CCCCCHHHHHHHHHHHHCCCCHHEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AMERDGQIIYTRNRCYITPENLKIVTGKVIGHRDGYGFLRTETFKDDLWLSIEQMKLCIH
HHCCCCCEEEECCEEEECCCCCEEEEEEEEECCCCCCCEEECCCCCCCEEEHHHHEEHHC
GDVILAHIVKSDRKGRNSAKVLKILRPNDVLIVGRYCVDNKKKFVIPNDTRFNFKIFILD
CHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEEEECCCCEEECCCCCCEEEEEEEEE
SLISNENISIGTIVVVKLRENATKKSKIQGTIVEVLGKEMGTNLAIKIALRTHCIPYLWS
HHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHCCHHHHHC
KEVEYQLCGIKSKINEKDFKNRIDLRHLPFFTIDEEDARDFDDAIFCKKKTNGEKGWKLW
CCCCEEEECCHHHCCHHHHHHCCCCEECCEEEECCHHCCCCCCCEEEECCCCCCCCEEEE
VAISDVSYYIQPDTALDKAASKRGTSIYFPSLVIPMLPEKISIDVCSLNPNAERLSLICE
EEEECEEEEECCCHHHHHHHHCCCCEEEECHHHHHCCCCCEEEEEEECCCCHHHEEEEEE
MNLSNKGELITYKHYEAVICSHGRFTYNEIFKIWNGDIELCFKYKKLLKYIQNLSSLQKI
ECCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LKKYNVSKRGIYFENIEAKFILDSNYRIKNISQNIRNDAHKFIESCMILANIASAEFVKK
HHHCCCCCCCEEEECCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKSPVLFRNHDRPDKDSIINFRSVLKKLGLSLLGGEIPESTDYSELLKKISTRPDYEMIQ
CCCCCEECCCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHH
TILLRSMKQAVYSPDNRGHFGLSLSSYVHFTSPIRRYPDLLVHRVIKNLLLKEKNLSKYH
HHHHHHHHHHHCCCCCCCEECEEHHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LYNLNEVTKIGLHCSMTERRADEATRDVLDWLKCDFMQKKIGDVLTGVISNVTSFGFFVR
EECCCHHHEECEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNQFFIDGLVHIATLIDDYYYFDSIGLKLIGKSSKNTYCLGDTLKVKVISVNLNERKIEL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCEEEEEEEEEECCCEEEEE
SLYMSR
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438