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The map label for this gene is uup

Identifier: 21672627

GI number: 21672627

Start: 399433

End: 401211

Strand: Direct

Name: uup

Synonym: BUsg352

Alternate gene names: 21672627

Gene position: 399433-401211 (Clockwise)

Preceding gene: 21672626

Following gene: 21672631

Centisome position: 62.27

GC content: 21.02

Gene sequence:

>1779_bases
ATGCCTCTAATCAGTATCCAAAATGCCTTTTTAGCATTCAGTGATTTAGAAATCTTGAAAAATGCTGTACTTTATATAAA
TAAAAAAGAAAGAATCAGTTTAATTGGAAAAAATGGTGCTGGAAAATCAACTTTATTAAAAGTAATTAATAAAAATCAAG
AATTAGATCATGGTTCTATTATTTATCAAAAAAATATAAAAATATCTTATTTAAAGCAAGATAACCCAAAAAATTTAGAT
ATTTCTATATATGATTTTATTAAAAATCAATTAAAAAAAGAAAACAACAAAGAAATAAATATTAATACAATTGTAGAAAT
AAAAAAAATAATTAAAACTTTTCAAATTGATAAACATTCTTTACTTTCAGAATTATCTGGAGGTTCTTTAAGAAAAGTGG
TACTAGGTTCAGCATTATTAAGTCAACCAGATGTTTTGTTACTTGACGAACCAACTAATCATTTGGATATTAACACTATT
GCATGGTTAGAAAAATTTTTAAAAAAATTTTCAGGAACAACATTGTTTATATCACATGATAGATCTTTTATTCAAAATTT
ATGCACAAGAATTATTGATCTTGATAGAGGAAAATTAACTTCTTTTCCAGGAGATTATAAAGAGTTTATAAAATTAAAAA
AAGAAAATAATCGGATTGAAAAAACAAAAAAAAAATTATTTGATCAACATTTAGAAAAAGAAGAAATCTGGATTAGAAAA
GGAATTAAAGCTCGTACTACTCGCAATGAAGGAAGAGTAAGAAATTTAAAAGTATTACGAAAAGAATATAAAAACTATAA
AAAAATAGAAAATTTCAATAATGTTATAATCAATGAAATTAAAAATTATTCAGGAAAAATAATTTTTAAATTAAAAAATA
TAAGTTTTTTTATTGAAAAAAAGACTATTATTCAAAGTTTTTCTTCAATAATACAATATGGTGATAAAATAGGATTAATA
GGTAACAACGGATCTGGAAAAAGTACTATGATAAAAATACTTATGGGAGAAAAAAAAATTCAAAAAGGTTCTATTCATTT
TGGAACAAAATTAAATATAGCATATTTCGATCAAGATCGATCAACTTTAGATTCTAATAAATCTATTTTAGAAAATGTAA
ATAATGGAAGAGAAAAAATCGTATTAAATGGAAAAGAACAACATTTGATAGGATATCTAAAAAAATTTCTTTTTAAACCA
AATCAAATGAAATGTTTGGTAAAAAATTTATCTGGAGGTGAATGTAATAGATTACTTTTAGCAAAATTATTCTTGAAACC
AAGTAATGTTTTAATTCTTGATGAACCGACAAATGATTTAGATTTAGATACACTTGAGTTATTAGAAAACATTATTATTA
AATATTCAGGAACAGTTTTAATAGTAAGTCATGACAGGAATTTTATTGAAAATACAGTAAATAAATATTGGATATTTAAA
GGAGATGGATTGATAAATACACATTTTAGTTCACATAACAATATAATAAAAGAAAAGAACAAAAAAATTCAAAAGAAATA
TGTATTAAATCCAATTAAATCTAATATTAGTTTTTTAAAAACAAAACAAAATCAAGTAAAAAAAGAACTAAAAAAAGTAT
TAAATGAAATAGAAAAAATAGAAAATAGTATTAAAACTTTGAAAATTCAAATGAATGAACCGGATTTTTTTAAACAGCAT
ATTAAAAATCAATTACCAATTGTAAAGCAATTTAATATAGAAGAAAAAAAATTAGAAAAAATATTAATATATTGGGAAAA
TTTAGAAAAAAAATTATAA

Upstream 100 bases:

>100_bases
AAAAATTACTAATTTAGTGAAAACAAAAGATTTTTTAAAAAAAAATTATCATTCTTGGTTAATAAAACACATTTAAAAAA
TTCAAAAAAAAGAGAAATAT

Downstream 100 bases:

>100_bases
ATTATTTTTTAAAAAAATAATTTATAGATGCTGCATACAGTATTTAGAACAACATTTTTTAAATTTTATTGTACAATCTT
TACATTGAATAAAAAGAAGA

Product: ABC transporter ATP-binding protein Uup

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MPLISIQNAFLAFSDLEILKNAVLYINKKERISLIGKNGAGKSTLLKVINKNQELDHGSIIYQKNIKISYLKQDNPKNLD
ISIYDFIKNQLKKENNKEININTIVEIKKIIKTFQIDKHSLLSELSGGSLRKVVLGSALLSQPDVLLLDEPTNHLDINTI
AWLEKFLKKFSGTTLFISHDRSFIQNLCTRIIDLDRGKLTSFPGDYKEFIKLKKENNRIEKTKKKLFDQHLEKEEIWIRK
GIKARTTRNEGRVRNLKVLRKEYKNYKKIENFNNVIINEIKNYSGKIIFKLKNISFFIEKKTIIQSFSSIIQYGDKIGLI
GNNGSGKSTMIKILMGEKKIQKGSIHFGTKLNIAYFDQDRSTLDSNKSILENVNNGREKIVLNGKEQHLIGYLKKFLFKP
NQMKCLVKNLSGGECNRLLLAKLFLKPSNVLILDEPTNDLDLDTLELLENIIIKYSGTVLIVSHDRNFIENTVNKYWIFK
GDGLINTHFSSHNNIIKEKNKKIQKKYVLNPIKSNISFLKTKQNQVKKELKKVLNEIEKIENSIKTLKIQMNEPDFFKQH
IKNQLPIVKQFNIEEKKLEKILIYWENLEKKL

Sequences:

>Translated_592_residues
MPLISIQNAFLAFSDLEILKNAVLYINKKERISLIGKNGAGKSTLLKVINKNQELDHGSIIYQKNIKISYLKQDNPKNLD
ISIYDFIKNQLKKENNKEININTIVEIKKIIKTFQIDKHSLLSELSGGSLRKVVLGSALLSQPDVLLLDEPTNHLDINTI
AWLEKFLKKFSGTTLFISHDRSFIQNLCTRIIDLDRGKLTSFPGDYKEFIKLKKENNRIEKTKKKLFDQHLEKEEIWIRK
GIKARTTRNEGRVRNLKVLRKEYKNYKKIENFNNVIINEIKNYSGKIIFKLKNISFFIEKKTIIQSFSSIIQYGDKIGLI
GNNGSGKSTMIKILMGEKKIQKGSIHFGTKLNIAYFDQDRSTLDSNKSILENVNNGREKIVLNGKEQHLIGYLKKFLFKP
NQMKCLVKNLSGGECNRLLLAKLFLKPSNVLILDEPTNDLDLDTLELLENIIIKYSGTVLIVSHDRNFIENTVNKYWIFK
GDGLINTHFSSHNNIIKEKNKKIQKKYVLNPIKSNISFLKTKQNQVKKELKKVLNEIEKIENSIKTLKIQMNEPDFFKQH
IKNQLPIVKQFNIEEKKLEKILIYWENLEKKL
>Mature_591_residues
PLISIQNAFLAFSDLEILKNAVLYINKKERISLIGKNGAGKSTLLKVINKNQELDHGSIIYQKNIKISYLKQDNPKNLDI
SIYDFIKNQLKKENNKEININTIVEIKKIIKTFQIDKHSLLSELSGGSLRKVVLGSALLSQPDVLLLDEPTNHLDINTIA
WLEKFLKKFSGTTLFISHDRSFIQNLCTRIIDLDRGKLTSFPGDYKEFIKLKKENNRIEKTKKKLFDQHLEKEEIWIRKG
IKARTTRNEGRVRNLKVLRKEYKNYKKIENFNNVIINEIKNYSGKIIFKLKNISFFIEKKTIIQSFSSIIQYGDKIGLIG
NNGSGKSTMIKILMGEKKIQKGSIHFGTKLNIAYFDQDRSTLDSNKSILENVNNGREKIVLNGKEQHLIGYLKKFLFKPN
QMKCLVKNLSGGECNRLLLAKLFLKPSNVLILDEPTNDLDLDTLELLENIIIKYSGTVLIVSHDRNFIENTVNKYWIFKG
DGLINTHFSSHNNIIKEKNKKIQKKYVLNPIKSNISFLKTKQNQVKKELKKVLNEIEKIENSIKTLKIQMNEPDFFKQHI
KNQLPIVKQFNIEEKKLEKILIYWENLEKKL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains

Homologues:

Organism=Homo sapiens, GI148612853, Length=552, Percent_Identity=28.0797101449275, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI27881506, Length=516, Percent_Identity=28.2945736434109, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI10947137, Length=516, Percent_Identity=28.2945736434109, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI10947135, Length=512, Percent_Identity=26.3671875, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI69354671, Length=512, Percent_Identity=26.3671875, Blast_Score=163, Evalue=4e-40,
Organism=Escherichia coli, GI1787182, Length=633, Percent_Identity=42.4960505529226, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI2367384, Length=503, Percent_Identity=33.2007952286282, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1789751, Length=645, Percent_Identity=27.1317829457364, Blast_Score=228, Evalue=9e-61,
Organism=Escherichia coli, GI1787041, Length=516, Percent_Identity=26.7441860465116, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI1788506, Length=554, Percent_Identity=24.0072202166065, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788165, Length=190, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789891, Length=206, Percent_Identity=26.2135922330097, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788761, Length=213, Percent_Identity=25.3521126760563, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787758, Length=223, Percent_Identity=25.1121076233184, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790467, Length=271, Percent_Identity=24.3542435424354, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790525, Length=493, Percent_Identity=21.501014198783, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787712, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081834, Length=208, Percent_Identity=26.4423076923077, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559834, Length=539, Percent_Identity=25.2319109461967, Blast_Score=165, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17553372, Length=534, Percent_Identity=29.0262172284644, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17555318, Length=543, Percent_Identity=25.0460405156538, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI115533608, Length=215, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=259, Percent_Identity=25.8687258687259, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=246, Percent_Identity=27.6422764227642, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=248, Percent_Identity=25, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=293, Percent_Identity=27.3037542662116, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=517, Percent_Identity=26.6924564796905, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321121, Length=516, Percent_Identity=28.8759689922481, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6325030, Length=378, Percent_Identity=27.2486772486773, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323278, Length=421, Percent_Identity=28.0285035629454, Blast_Score=121, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6324314, Length=353, Percent_Identity=28.0453257790368, Blast_Score=113, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24666836, Length=515, Percent_Identity=28.7378640776699, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24641342, Length=537, Percent_Identity=28.1191806331471, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24642252, Length=516, Percent_Identity=26.7441860465116, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI18859989, Length=516, Percent_Identity=26.7441860465116, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI85726357, Length=216, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221500365, Length=189, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007184, Length=189, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24659289, Length=222, Percent_Identity=27.4774774774775, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UUP_BUCAP (Q8K9I3)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660694.1
- ProteinModelPortal:   Q8K9I3
- EnsemblBacteria:   EBBUCT00000000180
- GeneID:   1005803
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg352
- GeneTree:   EBGT00050000007760
- HOGENOM:   HBG758042
- OMA:   WIRKGIK
- ProtClustDB:   CLSK315984
- BioCyc:   BAPH198804:BUSG352-MONOMER
- GO:   GO:0006810
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 68734; Mature: 68602

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLISIQNAFLAFSDLEILKNAVLYINKKERISLIGKNGAGKSTLLKVINKNQELDHGSI
CCCEEECHHHHHHHHHHHHHCHHEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCE
IYQKNIKISYLKQDNPKNLDISIYDFIKNQLKKENNKEININTIVEIKKIIKTFQIDKHS
EEEECCEEEEEECCCCCCCCEEHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCHHH
LLSELSGGSLRKVVLGSALLSQPDVLLLDEPTNHLDINTIAWLEKFLKKFSGTTLFISHD
HHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECC
RSFIQNLCTRIIDLDRGKLTSFPGDYKEFIKLKKENNRIEKTKKKLFDQHLEKEEIWIRK
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHC
GIKARTTRNEGRVRNLKVLRKEYKNYKKIENFNNVIINEIKNYSGKIIFKLKNISFFIEK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEHH
KTIIQSFSSIIQYGDKIGLIGNNGSGKSTMIKILMGEKKIQKGSIHFGTKLNIAYFDQDR
HHHHHHHHHHHHCCCCEEEEECCCCCHHHEEEEEECCCHHCCCCEEECEEEEEEEECCCC
STLDSNKSILENVNNGREKIVLNGKEQHLIGYLKKFLFKPNQMKCLVKNLSGGECNRLLL
HHHCCCHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHH
AKLFLKPSNVLILDEPTNDLDLDTLELLENIIIKYSGTVLIVSHDRNFIENTVNKYWIFK
HHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHEECCEEEEEECCCHHHHHCCCEEEEEE
GDGLINTHFSSHNNIIKEKNKKIQKKYVLNPIKSNISFLKTKQNQVKKELKKVLNEIEKI
CCCEEEECCCCCCCHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ENSIKTLKIQMNEPDFFKQHIKNQLPIVKQFNIEEKKLEKILIYWENLEKKL
HCCCEEEEEEECCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PLISIQNAFLAFSDLEILKNAVLYINKKERISLIGKNGAGKSTLLKVINKNQELDHGSI
CCEEECHHHHHHHHHHHHHCHHEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCE
IYQKNIKISYLKQDNPKNLDISIYDFIKNQLKKENNKEININTIVEIKKIIKTFQIDKHS
EEEECCEEEEEECCCCCCCCEEHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCHHH
LLSELSGGSLRKVVLGSALLSQPDVLLLDEPTNHLDINTIAWLEKFLKKFSGTTLFISHD
HHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECC
RSFIQNLCTRIIDLDRGKLTSFPGDYKEFIKLKKENNRIEKTKKKLFDQHLEKEEIWIRK
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHC
GIKARTTRNEGRVRNLKVLRKEYKNYKKIENFNNVIINEIKNYSGKIIFKLKNISFFIEK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEHH
KTIIQSFSSIIQYGDKIGLIGNNGSGKSTMIKILMGEKKIQKGSIHFGTKLNIAYFDQDR
HHHHHHHHHHHHCCCCEEEEECCCCCHHHEEEEEECCCHHCCCCEEECEEEEEEEECCCC
STLDSNKSILENVNNGREKIVLNGKEQHLIGYLKKFLFKPNQMKCLVKNLSGGECNRLLL
HHHCCCHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHH
AKLFLKPSNVLILDEPTNDLDLDTLELLENIIIKYSGTVLIVSHDRNFIENTVNKYWIFK
HHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHEECCEEEEEECCCHHHHHCCCEEEEEE
GDGLINTHFSSHNNIIKEKNKKIQKKYVLNPIKSNISFLKTKQNQVKKELKKVLNEIEKI
CCCEEEECCCCCCCHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ENSIKTLKIQMNEPDFFKQHIKNQLPIVKQFNIEEKKLEKILIYWENLEKKL
HCCCEEEEEEECCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438