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The map label for this gene is yoaE [C]

Identifier: 21672590

GI number: 21672590

Start: 360592

End: 362139

Strand: Direct

Name: yoaE [C]

Synonym: BUsg314

Alternate gene names: 21672590

Gene position: 360592-362139 (Clockwise)

Preceding gene: 21672589

Following gene: 21672591

Centisome position: 56.21

GC content: 28.68

Gene sequence:

>1548_bases
ATGGAGTTTTTTTTAGACCCGTCAATTTGGGCCGGCTTATTAACATTAGTTGTTTTAGAAGTAGTATTAGGGATTGATAA
TTTAATATTTGTAGCAATTTTATCAGAAAAATTACCTCCTAATCAAAGAGATAAGGCACGTTTAATTGGTTTAGGACTGG
CTTTAATTATGCGATTAGCGTTATTATCATTGATATCTTGGGTAGTAACACTCACTTCTCCTATTATTAGTAATAATTTT
TTTTCTTTGTCAATACGTGATTTAATATTACTTATTGGTGGTTTATTTCTTTTATTTAAAGCTACAATTGAATTACATGA
AAGACTAGAAAATGAAGACCATGAAAATACAGAAAATAAAAATTATGCCAGTTTTTGGGCTGTAGTTATTCAAATAGTTG
TATTAGATGCAGTGTTTTCCTTAGATGCAATAATTACAGCAGTGGGCATGGTAAATCAATTATTAATCATGATGATAGCA
GTTGTATTAGCTACAATATTAATGTTATTAGCATCGAAAGCATTAACAAATTTTATTAATATACATCAAACTGTAGTTGT
ATTATGCCTTAGTTTCTTATTAATGATTGGTTTTAGTTTAGTCGCAGAAGCTTTAAAGTTTTATATTCCAAAAGGATATT
TATATGCAGCAATAGGTTTTTCTATTTTAATCGAGATTTTTAATCAAATTGCTCGTCATAATTTTATGAAAAATCAATCT
AGAAAACCTATGAGACAAAGAGCAGCTGAAGCAATTTTACGTTTAATGATAAGAGAAAAGAATAACAATAAAAATAGAAT
AAAAACTGATAATAAAGCAGAAATAGTACTTTCATCTTCCTTAGAAACAGAAACTTTTAAAGATGAAGAAAAATATATGA
TTAATGGAGTTCTTACTTTAGCCGGTCGATCAATTAAAAGTATTATGACTCCACGAAGTAATATATCTTGGGTAAATACA
GAAAAAACAATCAATGAAATTCGATTACAATTATTAGATACACCTCATAATTTATTTCCTGTTTGTAAAGGTGAATTAGA
TGAAATAATCGGTATTGTACGAGCTAAGGAATTATTAGTCGCTATTGAAAAAAATATAGACGTTTATACATTTGCCTCTC
AAATACCACCTATTATTATACCAGATACTCTTGATCCTATAAATTTACTTGGAGTACTTCGTCGTGCTCAAGGTAGTTTT
GTAATTGTCAGTAATGAATTCGGTGTTGTTCAAGGATTAATTACACCTTTAGATGTTTTAGAAGCTATAGCAGGTGAATT
TCCAGACGCAGATGAAACTCCAGATATTATAAAAGAACAAAACAGCTGGTTAGTTAAGGGAGAAACAGATTTACATTCTT
TACAACAATTACTTAATACTAAAGAATTAATTAAACAAGATGACTGTGCTTCTTTAGGAGGATTGCTAATTTCTCAAAAA
GGTCAATTACCTCTCCCAGGAGAAACAATTAAGATTAATTCTTTTTCTTTTCACATTGTTAATGCTACAGAATATCGTAT
CGATTTAGTGAGAATAACTAAAAATTAA

Upstream 100 bases:

>100_bases
GATATAATAAAATATTATATAATCTCAAATTACATTATATCTTAAATATTTAGATATATTAAATATTGGGCTGTCCTATT
TTTTTTACGGAGTTTTTCTG

Downstream 100 bases:

>100_bases
GATATAAATAGCAAGTTTTCTAAGTAATTTTTTGTTTAAAAAAATTTTTTACTGAACTTATTTCGAGTAAGATATGTCTG
ACATAATTTTAGCCATTGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MEFFLDPSIWAGLLTLVVLEVVLGIDNLIFVAILSEKLPPNQRDKARLIGLGLALIMRLALLSLISWVVTLTSPIISNNF
FSLSIRDLILLIGGLFLLFKATIELHERLENEDHENTENKNYASFWAVVIQIVVLDAVFSLDAIITAVGMVNQLLIMMIA
VVLATILMLLASKALTNFINIHQTVVVLCLSFLLMIGFSLVAEALKFYIPKGYLYAAIGFSILIEIFNQIARHNFMKNQS
RKPMRQRAAEAILRLMIREKNNNKNRIKTDNKAEIVLSSSLETETFKDEEKYMINGVLTLAGRSIKSIMTPRSNISWVNT
EKTINEIRLQLLDTPHNLFPVCKGELDEIIGIVRAKELLVAIEKNIDVYTFASQIPPIIIPDTLDPINLLGVLRRAQGSF
VIVSNEFGVVQGLITPLDVLEAIAGEFPDADETPDIIKEQNSWLVKGETDLHSLQQLLNTKELIKQDDCASLGGLLISQK
GQLPLPGETIKINSFSFHIVNATEYRIDLVRITKN

Sequences:

>Translated_515_residues
MEFFLDPSIWAGLLTLVVLEVVLGIDNLIFVAILSEKLPPNQRDKARLIGLGLALIMRLALLSLISWVVTLTSPIISNNF
FSLSIRDLILLIGGLFLLFKATIELHERLENEDHENTENKNYASFWAVVIQIVVLDAVFSLDAIITAVGMVNQLLIMMIA
VVLATILMLLASKALTNFINIHQTVVVLCLSFLLMIGFSLVAEALKFYIPKGYLYAAIGFSILIEIFNQIARHNFMKNQS
RKPMRQRAAEAILRLMIREKNNNKNRIKTDNKAEIVLSSSLETETFKDEEKYMINGVLTLAGRSIKSIMTPRSNISWVNT
EKTINEIRLQLLDTPHNLFPVCKGELDEIIGIVRAKELLVAIEKNIDVYTFASQIPPIIIPDTLDPINLLGVLRRAQGSF
VIVSNEFGVVQGLITPLDVLEAIAGEFPDADETPDIIKEQNSWLVKGETDLHSLQQLLNTKELIKQDDCASLGGLLISQK
GQLPLPGETIKINSFSFHIVNATEYRIDLVRITKN
>Mature_515_residues
MEFFLDPSIWAGLLTLVVLEVVLGIDNLIFVAILSEKLPPNQRDKARLIGLGLALIMRLALLSLISWVVTLTSPIISNNF
FSLSIRDLILLIGGLFLLFKATIELHERLENEDHENTENKNYASFWAVVIQIVVLDAVFSLDAIITAVGMVNQLLIMMIA
VVLATILMLLASKALTNFINIHQTVVVLCLSFLLMIGFSLVAEALKFYIPKGYLYAAIGFSILIEIFNQIARHNFMKNQS
RKPMRQRAAEAILRLMIREKNNNKNRIKTDNKAEIVLSSSLETETFKDEEKYMINGVLTLAGRSIKSIMTPRSNISWVNT
EKTINEIRLQLLDTPHNLFPVCKGELDEIIGIVRAKELLVAIEKNIDVYTFASQIPPIIIPDTLDPINLLGVLRRAQGSF
VIVSNEFGVVQGLITPLDVLEAIAGEFPDADETPDIIKEQNSWLVKGETDLHSLQQLLNTKELIKQDDCASLGGLLISQK
GQLPLPGETIKINSFSFHIVNATEYRIDLVRITKN

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=243, Percent_Identity=25.1028806584362, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788119, Length=515, Percent_Identity=66.4077669902913, Blast_Score=689, Evalue=0.0,
Organism=Escherichia coli, GI87082033, Length=523, Percent_Identity=45.3154875717017, Blast_Score=404, Evalue=1e-113,
Organism=Escherichia coli, GI1789197, Length=225, Percent_Identity=47.5555555555556, Blast_Score=188, Evalue=8e-49,
Organism=Escherichia coli, GI1790664, Length=254, Percent_Identity=26.7716535433071, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786879, Length=244, Percent_Identity=26.6393442622951, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693175, Length=281, Percent_Identity=25.2669039145907, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y314_BUCAP (Q8K9M0)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660657.1
- ProteinModelPortal:   Q8K9M0
- SMR:   Q8K9M0
- EnsemblBacteria:   EBBUCT00000000463
- GeneID:   1005519
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg314
- GeneTree:   EBGT00050000007724
- HOGENOM:   HBG470183
- OMA:   QIARHNF
- ProtClustDB:   CLSK866497
- BioCyc:   BAPH198804:BUSG314-MONOMER
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC

EC number: NA

Molecular weight: Translated: 57609; Mature: 57609

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS51371 CBS; PS00027 HOMEOBOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb37fa88)-; HASH(0x40484710)-; HASH(0xbff940c)-; HASH(0x969512c)-; HASH(0xc6452e8)-; HASH(0x404866cc)-; HASH(0xae39b18)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFFLDPSIWAGLLTLVVLEVVLGIDNLIFVAILSEKLPPNQRDKARLIGLGLALIMRLA
CCCEECHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LLSLISWVVTLTSPIISNNFFSLSIRDLILLIGGLFLLFKATIELHERLENEDHENTENK
HHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NYASFWAVVIQIVVLDAVFSLDAIITAVGMVNQLLIMMIAVVLATILMLLASKALTNFIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHQTVVVLCLSFLLMIGFSLVAEALKFYIPKGYLYAAIGFSILIEIFNQIARHNFMKNQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RKPMRQRAAEAILRLMIREKNNNKNRIKTDNKAEIVLSSSLETETFKDEEKYMINGVLTL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHCCCCHHHHHHHHHHH
AGRSIKSIMTPRSNISWVNTEKTINEIRLQLLDTPHNLFPVCKGELDEIIGIVRAKELLV
HCHHHHHHHCCCCCCCEECHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AIEKNIDVYTFASQIPPIIIPDTLDPINLLGVLRRAQGSFVIVSNEFGVVQGLITPLDVL
HHHCCCCEEEEHHCCCCEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
EAIAGEFPDADETPDIIKEQNSWLVKGETDLHSLQQLLNTKELIKQDDCASLGGLLISQK
HHHHCCCCCCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHCCHHCCCC
GQLPLPGETIKINSFSFHIVNATEYRIDLVRITKN
CCCCCCCCEEEEECEEEEEEECEEEEEEEEEEECH
>Mature Secondary Structure
MEFFLDPSIWAGLLTLVVLEVVLGIDNLIFVAILSEKLPPNQRDKARLIGLGLALIMRLA
CCCEECHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LLSLISWVVTLTSPIISNNFFSLSIRDLILLIGGLFLLFKATIELHERLENEDHENTENK
HHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NYASFWAVVIQIVVLDAVFSLDAIITAVGMVNQLLIMMIAVVLATILMLLASKALTNFIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHQTVVVLCLSFLLMIGFSLVAEALKFYIPKGYLYAAIGFSILIEIFNQIARHNFMKNQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RKPMRQRAAEAILRLMIREKNNNKNRIKTDNKAEIVLSSSLETETFKDEEKYMINGVLTL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHCCCCHHHHHHHHHHH
AGRSIKSIMTPRSNISWVNTEKTINEIRLQLLDTPHNLFPVCKGELDEIIGIVRAKELLV
HCHHHHHHHCCCCCCCEECHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AIEKNIDVYTFASQIPPIIIPDTLDPINLLGVLRRAQGSFVIVSNEFGVVQGLITPLDVL
HHHCCCCEEEEHHCCCCEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
EAIAGEFPDADETPDIIKEQNSWLVKGETDLHSLQQLLNTKELIKQDDCASLGGLLISQK
HHHHCCCCCCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHCCHHCCCC
GQLPLPGETIKINSFSFHIVNATEYRIDLVRITKN
CCCCCCCCEEEEECEEEEEEECEEEEEEEEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438