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The map label for this gene is trxB

Identifier: 21672580

GI number: 21672580

Start: 348469

End: 349428

Strand: Direct

Name: trxB

Synonym: BUsg304

Alternate gene names: 21672580

Gene position: 348469-349428 (Clockwise)

Preceding gene: 21672573

Following gene: 21672581

Centisome position: 54.32

GC content: 26.35

Gene sequence:

>960_bases
ATGGAATTAAAAAATCATAAAAAAATAATAATTTTAGGTTCAGGACCAGCAGGATACACTGCTGCTATATATAGTTCTAG
AGCTAATTTAAATCCTTTATTAATTACTGGTATTAATAAAGGTGGTCAATTAATGAATACTAATGAAATTGAAAATTGGC
CTGGTGATTTTAAAAAAATTACTGGTCCTGAACTAATGAATCGTATGCATGAACATTCATTAAAATTTAAAACAGAAATT
GTATATGATAATATCATTTCAGTAGAATTTAAAAAAAAACCATTTTTTTTACTGGGAGAATATAATAAGTATACATGTGA
TGCAGTAATTATTGCTACAGGTGCAAATCCTCGTTATTTAGGATTAAGTTCAGAAAACAAATTTAAAGGAAAAGGTATTT
CTACTTGTGCTGTATGTGATGGTTTTTTTTATAAAAATAAGGAAATAGCAGTAGTAGGAGGAGGGAATACAGCTATAGAA
GAAACATTATATTTGTCAAATTTTGTAAAAAAAATATATTTAATTCATCGTAGAAACAATTTTAAAGCTGAAAAAATTCT
AATTGATCGATTATTAAAAATTGTAAAAACTAAAAAAGTGATCCTGCATTTAAATTCAACTATAGAAGACATTTTAGGCA
ATAATAAAGGTGTTACGCATTTACTAATTAAAAATAAAAATTTAAAAGAAAAGAAAAAACTAAAAATTGCAGTTTCTGGA
TTATTTGTTGCAATTGGTTATATCCCGAATACAGATATATTTACTGATCAATTAAAAATGAAAGATGGATATATTAAAAT
AAAAAAAGGGACACATGGAAACTATACACAAACGAATATACCAGGTGTATTTGCAGCAGGTGATGTAATTGATCATGTAT
ATAGACAAGCTATTACATCATCTGCTAGTGGTTGTATGGCTGCATTAGATAGCGAACGTTATCTTAATTCATTATCTTAA

Upstream 100 bases:

>100_bases
TTTTATTTAAATTAATAGAATATATTATTATTCCTTTTTTATAAAAAAATTTATATTTATATTTTATATGTCATTCTAAA
ATATTTTAAGGAAAAATAAC

Downstream 100 bases:

>100_bases
TCCTGTTATTTTAATAAATTAATAAAAACATACTAGTCAAAATGACTAGTATAAGATATAATAAAAAATGCTCAATATTT
TAATAATTCTTTAAAAATAA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MELKNHKKIIILGSGPAGYTAAIYSSRANLNPLLITGINKGGQLMNTNEIENWPGDFKKITGPELMNRMHEHSLKFKTEI
VYDNIISVEFKKKPFFLLGEYNKYTCDAVIIATGANPRYLGLSSENKFKGKGISTCAVCDGFFYKNKEIAVVGGGNTAIE
ETLYLSNFVKKIYLIHRRNNFKAEKILIDRLLKIVKTKKVILHLNSTIEDILGNNKGVTHLLIKNKNLKEKKKLKIAVSG
LFVAIGYIPNTDIFTDQLKMKDGYIKIKKGTHGNYTQTNIPGVFAAGDVIDHVYRQAITSSASGCMAALDSERYLNSLS

Sequences:

>Translated_319_residues
MELKNHKKIIILGSGPAGYTAAIYSSRANLNPLLITGINKGGQLMNTNEIENWPGDFKKITGPELMNRMHEHSLKFKTEI
VYDNIISVEFKKKPFFLLGEYNKYTCDAVIIATGANPRYLGLSSENKFKGKGISTCAVCDGFFYKNKEIAVVGGGNTAIE
ETLYLSNFVKKIYLIHRRNNFKAEKILIDRLLKIVKTKKVILHLNSTIEDILGNNKGVTHLLIKNKNLKEKKKLKIAVSG
LFVAIGYIPNTDIFTDQLKMKDGYIKIKKGTHGNYTQTNIPGVFAAGDVIDHVYRQAITSSASGCMAALDSERYLNSLS
>Mature_319_residues
MELKNHKKIIILGSGPAGYTAAIYSSRANLNPLLITGINKGGQLMNTNEIENWPGDFKKITGPELMNRMHEHSLKFKTEI
VYDNIISVEFKKKPFFLLGEYNKYTCDAVIIATGANPRYLGLSSENKFKGKGISTCAVCDGFFYKNKEIAVVGGGNTAIE
ETLYLSNFVKKIYLIHRRNNFKAEKILIDRLLKIVKTKKVILHLNSTIEDILGNNKGVTHLLIKNKNLKEKKKLKIAVSG
LFVAIGYIPNTDIFTDQLKMKDGYIKIKKGTHGNYTQTNIPGVFAAGDVIDHVYRQAITSSASGCMAALDSERYLNSLS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=59.2476489028213, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI87081763, Length=304, Percent_Identity=28.6184210526316, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6320560, Length=325, Percent_Identity=44.3076923076923, Blast_Score=261, Evalue=9e-71,
Organism=Saccharomyces cerevisiae, GI6321898, Length=324, Percent_Identity=42.5925925925926, Blast_Score=254, Evalue=9e-69,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRXB_BUCAP (P81433)

Other databases:

- EMBL:   L43549
- EMBL:   AE013218
- RefSeq:   NP_660647.1
- ProteinModelPortal:   P81433
- SMR:   P81433
- EnsemblBacteria:   EBBUCT00000000259
- GeneID:   1005508
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg304
- GeneTree:   EBGT00050000008065
- HOGENOM:   HBG669726
- OMA:   PSCGPCH
- ProtClustDB:   CLSK315876
- BioCyc:   BAPH198804:BUSG304-MONOMER
- GO:   GO:0005737
- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- PRINTS:   PR00368
- PRINTS:   PR00469
- TIGRFAMs:   TIGR01292

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.8.1.9

Molecular weight: Translated: 35544; Mature: 35544

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKNHKKIIILGSGPAGYTAAIYSSRANLNPLLITGINKGGQLMNTNEIENWPGDFKKI
CCCCCCCEEEEEECCCCCCEEEEEECCCCCCEEEEEEECCCCCEEECCCCCCCCCCHHCC
TGPELMNRMHEHSLKFKTEIVYDNIISVEFKKKPFFLLGEYNKYTCDAVIIATGANPRYL
CCHHHHHHHHHHCCEEEEEEEECCEEEEEECCCCEEEEECCCCEEEEEEEEEECCCCEEE
GLSSENKFKGKGISTCAVCDGFFYKNKEIAVVGGGNTAIEETLYLSNFVKKIYLIHRRNN
ECCCCCCCCCCCCCEEEEECCEEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEEECCCC
FKAEKILIDRLLKIVKTKKVILHLNSTIEDILGNNKGVTHLLIKNKNLKEKKKLKIAVSG
CCHHHHHHHHHHHHHHHCEEEEEECCHHHHHHCCCCCEEEEEEECCCCCCHHEEEEEEEE
LFVAIGYIPNTDIFTDQLKMKDGYIKIKKGTHGNYTQTNIPGVFAAGDVIDHVYRQAITS
EEEEEECCCCCCEEECEEEECCCEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHC
SASGCMAALDSERYLNSLS
CCCCHHHHHCHHHHHHHCC
>Mature Secondary Structure
MELKNHKKIIILGSGPAGYTAAIYSSRANLNPLLITGINKGGQLMNTNEIENWPGDFKKI
CCCCCCCEEEEEECCCCCCEEEEEECCCCCCEEEEEEECCCCCEEECCCCCCCCCCHHCC
TGPELMNRMHEHSLKFKTEIVYDNIISVEFKKKPFFLLGEYNKYTCDAVIIATGANPRYL
CCHHHHHHHHHHCCEEEEEEEECCEEEEEECCCCEEEEECCCCEEEEEEEEEECCCCEEE
GLSSENKFKGKGISTCAVCDGFFYKNKEIAVVGGGNTAIEETLYLSNFVKKIYLIHRRNN
ECCCCCCCCCCCCCEEEEECCEEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEEECCCC
FKAEKILIDRLLKIVKTKKVILHLNSTIEDILGNNKGVTHLLIKNKNLKEKKKLKIAVSG
CCHHHHHHHHHHHHHHHCEEEEEECCHHHHHHCCCCCEEEEEEECCCCCCHHEEEEEEEE
LFVAIGYIPNTDIFTDQLKMKDGYIKIKKGTHGNYTQTNIPGVFAAGDVIDHVYRQAITS
EEEEEECCCCCCEEECEEEECCCEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHC
SASGCMAALDSERYLNSLS
CCCCHHHHHCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438