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The map label for this gene is gpt

Identifier: 21672523

GI number: 21672523

Start: 280218

End: 280682

Strand: Direct

Name: gpt

Synonym: BUsg242

Alternate gene names: 21672523

Gene position: 280218-280682 (Clockwise)

Preceding gene: 21672522

Following gene: 21672524

Centisome position: 43.68

GC content: 32.9

Gene sequence:

>465_bases
ATGAGTGAGAAATATATTGTTACTTGGGATATGCTTCAAATTCATACTAGAATACTAGCTCATCGACTACTTAAAACAAA
AAATGCTTGGAACGGGATAATTGCTGTAAGCCGGGGAGGTCTTGTCCCCTCTGCTATATTAGCAAGGGAATTAGGTATTC
GATGTGTAGACACCGTATGTATTGCAAGCTATAATTATGATTGTTTACAAAAAAATAGAAAAATAATTAAAAAAGCAAGG
GGCGATGGAGAAAAGATTATTGTTGTAGACGATCTTGTTGACACAGGAGGGACAGCAAAAATTATTCGTAATTTGTACCC
AAAAGCATACTTTGTAACTATTTTTGCAAAACCGTTAGGTCGATTATTAGTAGATGATTATATTATCGACATTGATCAAA
ACATATGGATAGAACAACCATGGGATATGTCAATATCTTATATTTCACCTCTTATTAAAAAATAA

Upstream 100 bases:

>100_bases
ATCATTGACTTTTATTTTAATAATTATAAATCCTACAATAATTACAAATTATTTCCACTTTTCTAATAAATACTATTTTA
TAGTTTTGGATTTTTTTTTT

Downstream 100 bases:

>100_bases
TAATACTAATTTCAAAAATTAAAAAATTGTTTTTTATAAAAAATACTATAAAATTACATCAATAAATATGTATTAAATTG
TAAAAAAGGTACATTTATGA

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSEKYIVTWDMLQIHTRILAHRLLKTKNAWNGIIAVSRGGLVPSAILARELGIRCVDTVCIASYNYDCLQKNRKIIKKAR
GDGEKIIVVDDLVDTGGTAKIIRNLYPKAYFVTIFAKPLGRLLVDDYIIDIDQNIWIEQPWDMSISYISPLIKK

Sequences:

>Translated_154_residues
MSEKYIVTWDMLQIHTRILAHRLLKTKNAWNGIIAVSRGGLVPSAILARELGIRCVDTVCIASYNYDCLQKNRKIIKKAR
GDGEKIIVVDDLVDTGGTAKIIRNLYPKAYFVTIFAKPLGRLLVDDYIIDIDQNIWIEQPWDMSISYISPLIKK
>Mature_153_residues
SEKYIVTWDMLQIHTRILAHRLLKTKNAWNGIIAVSRGGLVPSAILARELGIRCVDTVCIASYNYDCLQKNRKIIKKARG
DGEKIIVVDDLVDTGGTAKIIRNLYPKAYFVTIFAKPLGRLLVDDYIIDIDQNIWIEQPWDMSISYISPLIKK

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily

Homologues:

Organism=Escherichia coli, GI1786433, Length=151, Percent_Identity=68.8741721854305, Blast_Score=219, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XGPT_BUCAP (Q8K9R8)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660590.1
- ProteinModelPortal:   Q8K9R8
- SMR:   Q8K9R8
- EnsemblBacteria:   EBBUCT00000000095
- GeneID:   1005443
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg242
- GeneTree:   EBGT00050000007835
- HOGENOM:   HBG503428
- OMA:   LVDTFIT
- ProtClustDB:   PRK09177
- BioCyc:   BAPH198804:BUSG242-MONOMER
- HAMAP:   MF_01903
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 17549; Mature: 17418

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 94-94 BINDING 137-137

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKYIVTWDMLQIHTRILAHRLLKTKNAWNGIIAVSRGGLVPSAILARELGIRCVDTVC
CCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHH
IASYNYDCLQKNRKIIKKARGDGEKIIVVDDLVDTGGTAKIIRNLYPKAYFVTIFAKPLG
HHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEHHHHHHHH
RLLVDDYIIDIDQNIWIEQPWDMSISYISPLIKK
HHHHHHEEEECCCCCEEECCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SEKYIVTWDMLQIHTRILAHRLLKTKNAWNGIIAVSRGGLVPSAILARELGIRCVDTVC
CCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHH
IASYNYDCLQKNRKIIKKARGDGEKIIVVDDLVDTGGTAKIIRNLYPKAYFVTIFAKPLG
HHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEHHHHHHHH
RLLVDDYIIDIDQNIWIEQPWDMSISYISPLIKK
HHHHHHEEEECCCCCEEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438