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The map label for this gene is nuoH

Identifier: 21672443

GI number: 21672443

Start: 172818

End: 173786

Strand: Direct

Name: nuoH

Synonym: BUsg153

Alternate gene names: 21672443

Gene position: 172818-173786 (Clockwise)

Preceding gene: 21672442

Following gene: 21672444

Centisome position: 26.94

GC content: 26.32

Gene sequence:

>969_bases
ATGAATTCTTTAGGAATCAATATTTATGAAATATTATTTCAAATTTTACATATAACGTTGATTATAATTTTTATTATTTT
TTTTGCAGCAACTTTAAGTATTTTGGAACGTAAATTTTTAGCATTTTTTCAAAATAGACATGGTCCTAATCGAGTCGGTT
GGTTTGGCAGTTTACAATTATGCGCTGATATGATTAAAATTTTATTCAAAGAAGATTGGGTTCCTCAATTTAGTAAAAAA
TCAATTTTTATTTTGTCTCCAATTATAGCTTTTGTTTCTTTATTGTTAGTTATTCCAACAATACCCTTTACACCTAATTT
TTTGATAATAAATCTAAATATAGGAATTTTATTTTTTTTAATGATGGCTTCTTTATCAGTTTATGCAGTATTATTTGCTG
GTTGGTCAAGTAATAATAAATATTCTTTATTAGGTGCGATTCGCGCTTCTGCTCAAACTTTGAGCTATGAAGTTTTTTTA
GGTTTATCATTAATGGGTGTAATAGCTCGATCAGGATCTTTTAATATAGTAGATATTGTTAATAGTCAAAAAGAAGTTTG
GAATGTTATACCCCAATTCTTTGGTTTTTTATGTTTTTTTATAGCTGGTATAGCTCTTTGTCATAGACATCCCTTTGATC
AACCTGAATCTGAACAAGAGTTAGCTGATGGGTATCATATTGAATATTCTGGTATGAAATTTGGTTTATTTTTTATTGGT
GAATACATTTCTATTATTACAGTTTCAGCATTAATTTCGACAGTTTTTTTTGGAGGATATTTTGGTTTTTGGGGATCTAG
TTTTTTTTGGCTTTTTTTAAAAACAGTTTTTTTTATTTTGATTTTTATTTTAATTCGAGCATCTTTACCAAGACCTAAAT
ACGATCAAATAATGTCTTTTGGATGGAAAATTTGTTTACCGTTAACGCTATTGAATTTAATTATAACAGCTTTTTTTATA
TTAATATAA

Upstream 100 bases:

>100_bases
AACATTTAACTTCAAAGCACATAGGTTTACCTATAGGAAGAAAAGGATTTCCTATCTCTCTTATAGGTGAAAAAGTCAAA
TCTTTATGGGAAGTTATGTC

Downstream 100 bases:

>100_bases
GCTTTATTAAGAGATAATTATATGACTGTAAAAGAAATTATTATTGGATTTTTACTGCAAATAAGAAGTATTTTGATGGT
TTTCAAAAACATATTTTCTA

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNSLGINIYEILFQILHITLIIIFIIFFAATLSILERKFLAFFQNRHGPNRVGWFGSLQLCADMIKILFKEDWVPQFSKK
SIFILSPIIAFVSLLLVIPTIPFTPNFLIINLNIGILFFLMMASLSVYAVLFAGWSSNNKYSLLGAIRASAQTLSYEVFL
GLSLMGVIARSGSFNIVDIVNSQKEVWNVIPQFFGFLCFFIAGIALCHRHPFDQPESEQELADGYHIEYSGMKFGLFFIG
EYISIITVSALISTVFFGGYFGFWGSSFFWLFLKTVFFILIFILIRASLPRPKYDQIMSFGWKICLPLTLLNLIITAFFI
LI

Sequences:

>Translated_322_residues
MNSLGINIYEILFQILHITLIIIFIIFFAATLSILERKFLAFFQNRHGPNRVGWFGSLQLCADMIKILFKEDWVPQFSKK
SIFILSPIIAFVSLLLVIPTIPFTPNFLIINLNIGILFFLMMASLSVYAVLFAGWSSNNKYSLLGAIRASAQTLSYEVFL
GLSLMGVIARSGSFNIVDIVNSQKEVWNVIPQFFGFLCFFIAGIALCHRHPFDQPESEQELADGYHIEYSGMKFGLFFIG
EYISIITVSALISTVFFGGYFGFWGSSFFWLFLKTVFFILIFILIRASLPRPKYDQIMSFGWKICLPLTLLNLIITAFFI
LI
>Mature_322_residues
MNSLGINIYEILFQILHITLIIIFIIFFAATLSILERKFLAFFQNRHGPNRVGWFGSLQLCADMIKILFKEDWVPQFSKK
SIFILSPIIAFVSLLLVIPTIPFTPNFLIINLNIGILFFLMMASLSVYAVLFAGWSSNNKYSLLGAIRASAQTLSYEVFL
GLSLMGVIARSGSFNIVDIVNSQKEVWNVIPQFFGFLCFFIAGIALCHRHPFDQPESEQELADGYHIEYSGMKFGLFFIG
EYISIITVSALISTVFFGGYFGFWGSSFFWLFLKTVFFILIFILIRASLPRPKYDQIMSFGWKICLPLTLLNLIITAFFI
LI

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family

Homologues:

Organism=Homo sapiens, GI251831107, Length=281, Percent_Identity=40.9252669039146, Blast_Score=205, Evalue=5e-53,
Organism=Escherichia coli, GI1788618, Length=321, Percent_Identity=68.5358255451713, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOH_BUCAP (Q8K9Y1)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660510.1
- EnsemblBacteria:   EBBUCT00000000511
- GeneID:   1005351
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg153
- GeneTree:   EBGT00050000007740
- HOGENOM:   HBG727670
- OMA:   MSWLTPE
- ProtClustDB:   PRK06076
- BioCyc:   BAPH198804:BUSG153-MONOMER
- HAMAP:   MF_01350
- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086
- PANTHER:   PTHR11432

Pfam domain/function: PF00146 NADHdh

EC number: =1.6.99.5

Molecular weight: Translated: 36697; Mature: 36697

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS00667 COMPLEX1_ND1_1; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc1ab868)-; HASH(0xc2f3c0c)-; HASH(0xc2eb528)-; HASH(0xc2e8154)-; HASH(0xc2ee980)-; HASH(0xc2f3e70)-; HASH(0xc2f3c9c)-; HASH(0x9696d6c)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLGINIYEILFQILHITLIIIFIIFFAATLSILERKFLAFFQNRHGPNRVGWFGSLQL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
CADMIKILFKEDWVPQFSKKSIFILSPIIAFVSLLLVIPTIPFTPNFLIINLNIGILFFL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHH
MMASLSVYAVLFAGWSSNNKYSLLGAIRASAQTLSYEVFLGLSLMGVIARSGSFNIVDIV
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
NSQKEVWNVIPQFFGFLCFFIAGIALCHRHPFDQPESEQELADGYHIEYSGMKFGLFFIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEECCCCHHHHHHH
EYISIITVSALISTVFFGGYFGFWGSSFFWLFLKTVFFILIFILIRASLPRPKYDQIMSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHC
GWKICLPLTLLNLIITAFFILI
CHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MNSLGINIYEILFQILHITLIIIFIIFFAATLSILERKFLAFFQNRHGPNRVGWFGSLQL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
CADMIKILFKEDWVPQFSKKSIFILSPIIAFVSLLLVIPTIPFTPNFLIINLNIGILFFL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHH
MMASLSVYAVLFAGWSSNNKYSLLGAIRASAQTLSYEVFLGLSLMGVIARSGSFNIVDIV
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
NSQKEVWNVIPQFFGFLCFFIAGIALCHRHPFDQPESEQELADGYHIEYSGMKFGLFFIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEECCCCHHHHHHH
EYISIITVSALISTVFFGGYFGFWGSSFFWLFLKTVFFILIFILIRASLPRPKYDQIMSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHC
GWKICLPLTLLNLIITAFFILI
CHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438