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The map label for this gene is surA

Identifier: 21672423

GI number: 21672423

Start: 146862

End: 148160

Strand: Direct

Name: surA

Synonym: BUsg133

Alternate gene names: 21672423

Gene position: 146862-148160 (Clockwise)

Preceding gene: 21672421

Following gene: 21672424

Centisome position: 22.9

GC content: 17.94

Gene sequence:

>1299_bases
ATGAAAGTATATTTTTTTTTAATTTTATATGTTTTTTTAAGTTTTTTTTCTATTACTTATTCTAAAGAATTAGAAATTGA
TAAAATTATTGCTATCGTAAATAATCAAATTATATTAAATAGTGATGTAAATCAAGTTCTTTTTTCGTTAAAAGAAGAAG
ATCAAAGAGTAAAAATACCTTTAAAAATTAATTTTTTAAGAAATAAAATAATTAAAAAATTAATTACAGAAACTTTAATT
TTAGAAGAAGCAAAAAAATTTAATATTGTAGTAACTGATGATCAAGTAAATAATGTACTTAGTAAATACGCTTTAAAAAA
AAATATTACTATTGAAGAATTAAAAAGAAATATATTAATGAACAATACTAATACTTCTTTCAGTTACAATGATTATTTTA
ACAAGATTAAAAATTCATTAAAAGTTAAAATTATTCAAGATTATGTGTTACATAATCGCGTTCATATTTCAGAAAAAGAA
GTAGATTTATTTTTAAATAAACTAATAAATACTCAAAATGAATTAAAAAAAATAGATATTAATTGTATTTTTCTACCTTT
TATAAAAGAAAAAAATAAAATTTTTATTAAAAATACAAAAATTTTAGCAGATCATTTTGCCAAAAAAATAAAGAAAGATG
CTTCTTTCAACTATTATTATGAATATTTTAAAAAAAATAATAATATATTTTTATCAAAAGAAATAAGATCTAAATCGTTA
AAATATTTAAAAAAAATATTCTTGAATAAATTAAAAATTATTAAAAAAAATCAAATATTAGGTCCTATTTTAGGATTGAA
AGGTTTTTATATTTTAAAAATAAATAAAATTGAAAACGAGAATAAAGAAAACTTGACAACTGAATTTCATATACAACATT
GTTTAATACGTCCTTCTGTTATTTTAGATGATAAACAAGCAAAAAATAGTATATATTATATATATAATAATATTAAAAAC
AAAAAATATAGTTTCGATTACGCTGTTCAAAAGCTATCTCATGATGTTTATTCATCTCACAAAAAAGGTGACTTAGGATG
GATTTCAACTGATTTTTTTAGCAATGATTTTCGCAATTTTTTGACTGATTTAAGAAAAAATGAAATCAGTAAACCAATTA
AATCTAATTTTGGATGGCATATAATTAAGTTGTTAGATATACGTCAAGTAGATAAATCCAATAGAATAGATAAAAATTTA
GTTTATCGTTTTTTGTTAGAAAAAAAGATAAAAAAAGAAAGATATAATTGGATAAGACAACTAAAAAAATCATCTTATAT
TAAGATTTTTAAAAATTAA

Upstream 100 bases:

>100_bases
TTAAAATTATAACAAAAAATAATTAAAAATTAATATTTTGAGAAAATTTAAGCATTTTTTCTAAAAAAATCAAGAAAATT
TAAAAGAAAGAAGAATAATA

Downstream 100 bases:

>100_bases
TTAAATTTAAAATTAACTTTTTAGTAAAAAAAGTTTAATTCTTATATCAAGTAATTACTATATTCTAATGAAAAAAAAAA
TAAAAAAACATTTGCCTCTT

Product: survival protein SurA precursor

Products: Isomerized Proline [C]

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MKVYFFLILYVFLSFFSITYSKELEIDKIIAIVNNQIILNSDVNQVLFSLKEEDQRVKIPLKINFLRNKIIKKLITETLI
LEEAKKFNIVVTDDQVNNVLSKYALKKNITIEELKRNILMNNTNTSFSYNDYFNKIKNSLKVKIIQDYVLHNRVHISEKE
VDLFLNKLINTQNELKKIDINCIFLPFIKEKNKIFIKNTKILADHFAKKIKKDASFNYYYEYFKKNNNIFLSKEIRSKSL
KYLKKIFLNKLKIIKKNQILGPILGLKGFYILKINKIENENKENLTTEFHIQHCLIRPSVILDDKQAKNSIYYIYNNIKN
KKYSFDYAVQKLSHDVYSSHKKGDLGWISTDFFSNDFRNFLTDLRKNEISKPIKSNFGWHIIKLLDIRQVDKSNRIDKNL
VYRFLLEKKIKKERYNWIRQLKKSSYIKIFKN

Sequences:

>Translated_432_residues
MKVYFFLILYVFLSFFSITYSKELEIDKIIAIVNNQIILNSDVNQVLFSLKEEDQRVKIPLKINFLRNKIIKKLITETLI
LEEAKKFNIVVTDDQVNNVLSKYALKKNITIEELKRNILMNNTNTSFSYNDYFNKIKNSLKVKIIQDYVLHNRVHISEKE
VDLFLNKLINTQNELKKIDINCIFLPFIKEKNKIFIKNTKILADHFAKKIKKDASFNYYYEYFKKNNNIFLSKEIRSKSL
KYLKKIFLNKLKIIKKNQILGPILGLKGFYILKINKIENENKENLTTEFHIQHCLIRPSVILDDKQAKNSIYYIYNNIKN
KKYSFDYAVQKLSHDVYSSHKKGDLGWISTDFFSNDFRNFLTDLRKNEISKPIKSNFGWHIIKLLDIRQVDKSNRIDKNL
VYRFLLEKKIKKERYNWIRQLKKSSYIKIFKN
>Mature_432_residues
MKVYFFLILYVFLSFFSITYSKELEIDKIIAIVNNQIILNSDVNQVLFSLKEEDQRVKIPLKINFLRNKIIKKLITETLI
LEEAKKFNIVVTDDQVNNVLSKYALKKNITIEELKRNILMNNTNTSFSYNDYFNKIKNSLKVKIIQDYVLHNRVHISEKE
VDLFLNKLINTQNELKKIDINCIFLPFIKEKNKIFIKNTKILADHFAKKIKKDASFNYYYEYFKKNNNIFLSKEIRSKSL
KYLKKIFLNKLKIIKKNQILGPILGLKGFYILKINKIENENKENLTTEFHIQHCLIRPSVILDDKQAKNSIYYIYNNIKN
KKYSFDYAVQKLSHDVYSSHKKGDLGWISTDFFSNDFRNFLTDLRKNEISKPIKSNFGWHIIKLLDIRQVDKSNRIDKNL
VYRFLLEKKIKKERYNWIRQLKKSSYIKIFKN

Specific function: Chaperone involved in the folding of extracytoplasmic proteins

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains

Homologues:

Organism=Escherichia coli, GI1786238, Length=434, Percent_Identity=28.8018433179723, Blast_Score=232, Evalue=3e-62,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SURA_BUCAP (Q8KA01)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660490.1
- ProteinModelPortal:   Q8KA01
- SMR:   Q8KA01
- EnsemblBacteria:   EBBUCT00000000107
- GeneID:   1005950
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg133
- GeneTree:   EBGT00050000008069
- HOGENOM:   HBG366212
- OMA:   RHILIKT
- ProtClustDB:   CLSK315493
- BioCyc:   BAPH198804:BUSG133-MONOMER
- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: 5.2.1.8 [C]

Molecular weight: Translated: 51748; Mature: 51748

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYFFLILYVFLSFFSITYSKELEIDKIIAIVNNQIILNSDVNQVLFSLKEEDQRVKIP
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHCCCCEEEEE
LKINFLRNKIIKKLITETLILEEAKKFNIVVTDDQVNNVLSKYALKKNITIEELKRNILM
EEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHEE
NNTNTSFSYNDYFNKIKNSLKVKIIQDYVLHNRVHISEKEVDLFLNKLINTQNELKKIDI
CCCCCCCCHHHHHHHHHHHHEEHHHHHHHHHCCEECCHHHHHHHHHHHHCCHHHHEEEEC
NCIFLPFIKEKNKIFIKNTKILADHFAKKIKKDASFNYYYEYFKKNNNIFLSKEIRSKSL
EEEEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHEEECCCCEEEEHHHHHHHH
KYLKKIFLNKLKIIKKNQILGPILGLKGFYILKINKIENENKENLTTEFHIQHCLIRPSV
HHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEEECCCCCCCCCCHHEEHHHHHCCCCE
ILDDKQAKNSIYYIYNNIKNKKYSFDYAVQKLSHDVYSSHKKGDLGWISTDFFSNDFRNF
EECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHH
LTDLRKNEISKPIKSNFGWHIIKLLDIRQVDKSNRIDKNLVYRFLLEKKIKKERYNWIRQ
HHHHHHHHCCCHHHCCCCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKKSSYIKIFKN
HHCCCCEEEECC
>Mature Secondary Structure
MKVYFFLILYVFLSFFSITYSKELEIDKIIAIVNNQIILNSDVNQVLFSLKEEDQRVKIP
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHCCCCEEEEE
LKINFLRNKIIKKLITETLILEEAKKFNIVVTDDQVNNVLSKYALKKNITIEELKRNILM
EEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHEE
NNTNTSFSYNDYFNKIKNSLKVKIIQDYVLHNRVHISEKEVDLFLNKLINTQNELKKIDI
CCCCCCCCHHHHHHHHHHHHEEHHHHHHHHHCCEECCHHHHHHHHHHHHCCHHHHEEEEC
NCIFLPFIKEKNKIFIKNTKILADHFAKKIKKDASFNYYYEYFKKNNNIFLSKEIRSKSL
EEEEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHEEECCCCEEEEHHHHHHHH
KYLKKIFLNKLKIIKKNQILGPILGLKGFYILKINKIENENKENLTTEFHIQHCLIRPSV
HHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEEECCCCCCCCCCHHEEHHHHHCCCCE
ILDDKQAKNSIYYIYNNIKNKKYSFDYAVQKLSHDVYSSHKKGDLGWISTDFFSNDFRNF
EECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHH
LTDLRKNEISKPIKSNFGWHIIKLLDIRQVDKSNRIDKNLVYRFLLEKKIKKERYNWIRQ
HHHHHHHHCCCHHHCCCCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKKSSYIKIFKN
HHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proline Imidic Peptide Bonds In Oligopeptides [C]

Specific reaction: Cis-Trans Isomerization Of Proline Imidic Peptide Bonds In Oligopeptides. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438