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The map label for this gene is aroH [H]

Identifier: 21672407

GI number: 21672407

Start: 129783

End: 130829

Strand: Direct

Name: aroH [H]

Synonym: BUsg116

Alternate gene names: 21672407

Gene position: 129783-130829 (Clockwise)

Preceding gene: 21672406

Following gene: 21672408

Centisome position: 20.23

GC content: 31.9

Gene sequence:

>1047_bases
ATGAAAAAAACAGATGAACTACGTACAATACGAATTGATCCATTGATAACACCATCTGAATTAGCAAAAAAATATGCTAT
TACTTCAGAAATCATGGATAATGTTATTATAACGAGACAAAATATAGCTCGAATTATGACTGGAGAAGATTTGCGTTTGC
TTGTTGTAATAGGTCCATGTTCAGTACATGATCCAATTGCAGCAGTTGAATATGCTCATCGATTATATGAACTACGTAAA
AAATATCAAGATCGTCTTGAAATTATAATGCGTACATATTTTGAAAAACCAAGAACAGTAGTTGGTTGGAAGGGATTAAT
TTCAGATCCAGATTTAAATGGTAGTTTCAGAGTTAATCATGGTTTAGCTGTTGCACGTAAATTATTATTAGATATCAATG
AACTAGGAATGCCTGCAGCAACAGAGTTTTTAGATATGGTAATAGGGCAATTTATTGCGGATTTAATTAGCTGGGGTGCG
ATTGGAGCTAGAACTACTGAAAGTCAAATTCATAGAGAAATGGCTTCAGCTCTTTCTTGTCCAGTAGGTTTTAAAAATGG
AACAGATGGAAATATACGTATTGCAATTGATGCTATTAGAGCAGCACAAGCACGTCATTTGTTTTTTGCTCCGAATAAAG
ATGGACAAATGACTATTAATCATACCAGTGGAAATCCTTATGGACATATAATTATGAGAGGTGGTCGAACTCCTAATTAT
CATGCTCACGATATTAATTCAGCAATAGAACATTTACGTGAATTTAATTTGTTAGAACATTTAATGATTGATTTTAGTCA
TGGTAATTGTTTAAAGGAACATATTCGTCAAAAAGATGTTGCTAAATCTGTTTCAAAACAAATTTCTCAAGGTTCAAAAA
CTATATTTGGTGTAATGATTGAAAGTTTTTTAGAAGAAGGTTTTCAAACAGTTAAAGAAAATCAACCACTAATATATGGA
AAATCAATTACTGATGCATGTTTAAATTGGAAAGACAGTGTCCTTATTATTAAGCAATTAGCAGATGCGGTAGATACTCG
TTTTTAA

Upstream 100 bases:

>100_bases
TAAAAATTTATTAGAAATGAGTTTATGACTAGTTAGTTTATCGTGATTTTATCACATCTTGCTATTCTTTTCAGGATAAA
AAATTCATTTAGAGAACAAA

Downstream 100 bases:

>100_bases
TAATTATTGTGTATGCTAGTCAAAAATTTGACTAGCATCTTTTTATTAAACTCAACAGTTGAAATTTTTTAAATAATTTT
TAAAAAATAATATTTTTTTA

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKKTDELRTIRIDPLITPSELAKKYAITSEIMDNVIITRQNIARIMTGEDLRLLVVIGPCSVHDPIAAVEYAHRLYELRK
KYQDRLEIIMRTYFEKPRTVVGWKGLISDPDLNGSFRVNHGLAVARKLLLDINELGMPAATEFLDMVIGQFIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNIRIAIDAIRAAQARHLFFAPNKDGQMTINHTSGNPYGHIIMRGGRTPNY
HAHDINSAIEHLREFNLLEHLMIDFSHGNCLKEHIRQKDVAKSVSKQISQGSKTIFGVMIESFLEEGFQTVKENQPLIYG
KSITDACLNWKDSVLIIKQLADAVDTRF

Sequences:

>Translated_348_residues
MKKTDELRTIRIDPLITPSELAKKYAITSEIMDNVIITRQNIARIMTGEDLRLLVVIGPCSVHDPIAAVEYAHRLYELRK
KYQDRLEIIMRTYFEKPRTVVGWKGLISDPDLNGSFRVNHGLAVARKLLLDINELGMPAATEFLDMVIGQFIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNIRIAIDAIRAAQARHLFFAPNKDGQMTINHTSGNPYGHIIMRGGRTPNY
HAHDINSAIEHLREFNLLEHLMIDFSHGNCLKEHIRQKDVAKSVSKQISQGSKTIFGVMIESFLEEGFQTVKENQPLIYG
KSITDACLNWKDSVLIIKQLADAVDTRF
>Mature_348_residues
MKKTDELRTIRIDPLITPSELAKKYAITSEIMDNVIITRQNIARIMTGEDLRLLVVIGPCSVHDPIAAVEYAHRLYELRK
KYQDRLEIIMRTYFEKPRTVVGWKGLISDPDLNGSFRVNHGLAVARKLLLDINELGMPAATEFLDMVIGQFIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNIRIAIDAIRAAQARHLFFAPNKDGQMTINHTSGNPYGHIIMRGGRTPNY
HAHDINSAIEHLREFNLLEHLMIDFSHGNCLKEHIRQKDVAKSVSKQISQGSKTIFGVMIESFLEEGFQTVKENQPLIYG
KSITDACLNWKDSVLIIKQLADAVDTRF

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=348, Percent_Identity=68.6781609195402, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=55.9420289855072, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1788953, Length=327, Percent_Identity=48.6238532110092, Blast_Score=334, Evalue=5e-93,
Organism=Saccharomyces cerevisiae, GI6320240, Length=354, Percent_Identity=43.7853107344633, Blast_Score=305, Evalue=9e-84,
Organism=Saccharomyces cerevisiae, GI6319726, Length=346, Percent_Identity=45.6647398843931, Blast_Score=303, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39149; Mature: 39149

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTDELRTIRIDPLITPSELAKKYAITSEIMDNVIITRQNIARIMTGEDLRLLVVIGPC
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
SVHDPIAAVEYAHRLYELRKKYQDRLEIIMRTYFEKPRTVVGWKGLISDPDLNGSFRVNH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECH
GLAVARKLLLDINELGMPAATEFLDMVIGQFIADLISWGAIGARTTESQIHREMASALSC
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNIRIAIDAIRAAQARHLFFAPNKDGQMTINHTSGNPYGHIIMRGGRTPNY
CCCCCCCCCCEEEEEEEHHHHHHHCEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCC
HAHDINSAIEHLREFNLLEHLMIDFSHGNCLKEHIRQKDVAKSVSKQISQGSKTIFGVMI
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ESFLEEGFQTVKENQPLIYGKSITDACLNWKDSVLIIKQLADAVDTRF
HHHHHHHHHHHHCCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKTDELRTIRIDPLITPSELAKKYAITSEIMDNVIITRQNIARIMTGEDLRLLVVIGPC
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
SVHDPIAAVEYAHRLYELRKKYQDRLEIIMRTYFEKPRTVVGWKGLISDPDLNGSFRVNH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECH
GLAVARKLLLDINELGMPAATEFLDMVIGQFIADLISWGAIGARTTESQIHREMASALSC
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNIRIAIDAIRAAQARHLFFAPNKDGQMTINHTSGNPYGHIIMRGGRTPNY
CCCCCCCCCCEEEEEEEHHHHHHHCEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCC
HAHDINSAIEHLREFNLLEHLMIDFSHGNCLKEHIRQKDVAKSVSKQISQGSKTIFGVMI
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ESFLEEGFQTVKENQPLIYGKSITDACLNWKDSVLIIKQLADAVDTRF
HHHHHHHHHHHHCCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]