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The map label for this gene is atpD

Identifier: 21672302

GI number: 21672302

Start: 6783

End: 8183

Strand: Direct

Name: atpD

Synonym: BUsg008

Alternate gene names: 21672302

Gene position: 6783-8183 (Clockwise)

Preceding gene: 21672301

Following gene: 21672303

Centisome position: 1.06

GC content: 33.12

Gene sequence:

>1401_bases
ATGATAGCTACTGGAAAAATTATTCAAATTATTGGTGCCGTAGTAGATGTAGAATTTGATCAAAATTCAGTACCAAAGAT
ATATAACGCTCTAGAAGTAAAAAATAAAAAAATACAACTTATTTTAGAAGTACAGCAACAATTAGGTGCTGGAATTGTAC
GAACAATAGCTATGGGTTCTACTAATGGTTTGAAAAGGGGATTGATTGTTATTGATCTTGGACACTATATTAAAGTTCCG
GTAGGGCAAGCTACGTTAGGTCGCATAATTAATGTGTTAGGAAAAACAATAGACAATAAAGGACCATTAAAAAATTTAGA
TAATTCTAAATTAGAGTACTGGGAAATTCATCGTTCTGCACCAAGTTATCAAGAACAAGCATCTTCTCAAGAAATATTGG
AAACGGGTATAAAAGTTATTGATTTAATTTGTCCTTTTTCAAAAGGTGGAAAAGTTGGTTTATTTGGTGGAGCAGGTGTA
GGTAAAACAGTTAATATGATGGAATTGATTAGAAATATTGCAATAGAACATTCTGGTTATTCAGTATTTACTGGGGTTGG
TGAAAGAACTCGTGAAGGTAATGATTTTTATCATGAAATGAAAGATTCTAAAGTATTAGATAAAGTTTCTCTTGTCTACG
GTCAGATGAATGAACCTCCTGGTAATCGATTACGTGTGGCTTTTACAGGATTAACTATTGCTGAAAAATTTCGTGATGAA
GGTAGAGATGTTTTGTTATTTATTGATAATATATATCGTTATACCTTAGCTGGAACAGAAGTTTCTGCACTTCTTGGTCG
AATGCCCTCTGCTGTAGGTTATCAACCAACCTTAGCTGAAGAAATGGGCTTGCTTCAAGAAAGAATTACCTCGACTAAAG
AAGGTTCCATTACATCTGTTCAAGCAGTATATGTTCCAGCTGATGATTTAACTGATCCCTCTCCAGCTACTACGTTTGCG
CATTTAGATTCTACAGTAACATTAAGTCGTCAAATAGCTGCTTTAGGTATTTATCCAGCTATTGATCCTTTAAATTCGAC
TAGTCGTCAATTAGATCCTTATATTGTAGGCGACGAACATTATGATACAGCGCGAGGGGTACAGTCAATCTTACAAAGAT
ATCAAGAACTAAAAGATATTATTGCAATTTTAGGCATGGACGAATTATCTCAAGAAGATAAAATTTTAGTTTCAAGAGCG
CGCAAGATACAGAGATTTTTATCTCAACCATTTTTTGTAGCAGAAGTTTTTACTGGTTTTCCAGGAAAATATGTATCTTT
AAAAGATAATATTCGTGCTTTTAAAGGAATTATTGGAGGTGAATTTGATAATTTACCAGAGCAGGCGTTTTATATGGTAG
GTACTATTGAAGAAGTAATAAAAAAAGCAAAATTATTATAA

Upstream 100 bases:

>100_bases
TAATAAAGTTCGTCAAGCTAACATTACTCAAGAATTGACTGAAATTGTTGCAGGAGCATCAGCAGTATCAGTAGATTAAA
AATTGGTTAGAGGTTTTAAA

Downstream 100 bases:

>100_bases
TTAAATATTTTGGATATATCCATGGATTTTTACTTAGATATTGTTAGTGTTGAAAAGCGCATATTTTCTGGATTAGTCGA
TAGAATACAGGTATCTGGAA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MIATGKIIQIIGAVVDVEFDQNSVPKIYNALEVKNKKIQLILEVQQQLGAGIVRTIAMGSTNGLKRGLIVIDLGHYIKVP
VGQATLGRIINVLGKTIDNKGPLKNLDNSKLEYWEIHRSAPSYQEQASSQEILETGIKVIDLICPFSKGGKVGLFGGAGV
GKTVNMMELIRNIAIEHSGYSVFTGVGERTREGNDFYHEMKDSKVLDKVSLVYGQMNEPPGNRLRVAFTGLTIAEKFRDE
GRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGLLQERITSTKEGSITSVQAVYVPADDLTDPSPATTFA
HLDSTVTLSRQIAALGIYPAIDPLNSTSRQLDPYIVGDEHYDTARGVQSILQRYQELKDIIAILGMDELSQEDKILVSRA
RKIQRFLSQPFFVAEVFTGFPGKYVSLKDNIRAFKGIIGGEFDNLPEQAFYMVGTIEEVIKKAKLL

Sequences:

>Translated_466_residues
MIATGKIIQIIGAVVDVEFDQNSVPKIYNALEVKNKKIQLILEVQQQLGAGIVRTIAMGSTNGLKRGLIVIDLGHYIKVP
VGQATLGRIINVLGKTIDNKGPLKNLDNSKLEYWEIHRSAPSYQEQASSQEILETGIKVIDLICPFSKGGKVGLFGGAGV
GKTVNMMELIRNIAIEHSGYSVFTGVGERTREGNDFYHEMKDSKVLDKVSLVYGQMNEPPGNRLRVAFTGLTIAEKFRDE
GRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGLLQERITSTKEGSITSVQAVYVPADDLTDPSPATTFA
HLDSTVTLSRQIAALGIYPAIDPLNSTSRQLDPYIVGDEHYDTARGVQSILQRYQELKDIIAILGMDELSQEDKILVSRA
RKIQRFLSQPFFVAEVFTGFPGKYVSLKDNIRAFKGIIGGEFDNLPEQAFYMVGTIEEVIKKAKLL
>Mature_466_residues
MIATGKIIQIIGAVVDVEFDQNSVPKIYNALEVKNKKIQLILEVQQQLGAGIVRTIAMGSTNGLKRGLIVIDLGHYIKVP
VGQATLGRIINVLGKTIDNKGPLKNLDNSKLEYWEIHRSAPSYQEQASSQEILETGIKVIDLICPFSKGGKVGLFGGAGV
GKTVNMMELIRNIAIEHSGYSVFTGVGERTREGNDFYHEMKDSKVLDKVSLVYGQMNEPPGNRLRVAFTGLTIAEKFRDE
GRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGLLQERITSTKEGSITSVQAVYVPADDLTDPSPATTFA
HLDSTVTLSRQIAALGIYPAIDPLNSTSRQLDPYIVGDEHYDTARGVQSILQRYQELKDIIAILGMDELSQEDKILVSRA
RKIQRFLSQPFFVAEVFTGFPGKYVSLKDNIRAFKGIIGGEFDNLPEQAFYMVGTIEEVIKKAKLL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=471, Percent_Identity=67.7282377919321, Blast_Score=641, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=352, Percent_Identity=27.8409090909091, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI50345984, Length=308, Percent_Identity=25, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4757810, Length=308, Percent_Identity=25, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI19913428, Length=365, Percent_Identity=24.6575342465753, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI19913426, Length=365, Percent_Identity=24.1095890410959, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1790170, Length=465, Percent_Identity=82.1505376344086, Blast_Score=793, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=310, Percent_Identity=29.3548387096774, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1790172, Length=313, Percent_Identity=26.1980830670927, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=471, Percent_Identity=66.4543524416136, Blast_Score=624, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI17565854, Length=326, Percent_Identity=28.5276073619632, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=353, Percent_Identity=24.929178470255, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71988080, Length=308, Percent_Identity=25.6493506493506, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=308, Percent_Identity=25.6493506493506, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=353, Percent_Identity=23.7960339943343, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988074, Length=269, Percent_Identity=24.5353159851301, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322581, Length=463, Percent_Identity=67.170626349892, Blast_Score=628, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319370, Length=316, Percent_Identity=26.8987341772152, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319603, Length=356, Percent_Identity=26.123595505618, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320016, Length=284, Percent_Identity=26.4084507042254, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24638766, Length=469, Percent_Identity=66.7377398720682, Blast_Score=622, Evalue=1e-178,
Organism=Drosophila melanogaster, GI28574560, Length=471, Percent_Identity=62.6326963906582, Blast_Score=580, Evalue=1e-166,
Organism=Drosophila melanogaster, GI20129479, Length=340, Percent_Identity=27.6470588235294, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583992, Length=365, Percent_Identity=27.1232876712329, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24583988, Length=330, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24583986, Length=330, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24583984, Length=330, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=60.8695652173913, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24658560, Length=308, Percent_Identity=25.6493506493506, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281361666, Length=412, Percent_Identity=24.2718446601942, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24646341, Length=412, Percent_Identity=24.2718446601942, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17136796, Length=412, Percent_Identity=24.2718446601942, Blast_Score=99, Evalue=7e-21,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_BUCAP (Q07232)

Other databases:

- EMBL:   AF008210
- EMBL:   AE013218
- EMBL:   Z15147
- EMBL:   AJ247128
- PIR:   S37647
- RefSeq:   NP_660369.1
- ProteinModelPortal:   Q07232
- SMR:   Q07232
- EnsemblBacteria:   EBBUCT00000000222
- GeneID:   1005596
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg008
- GeneTree:   EBGT00050000007862
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- ProtClustDB:   PRK09280
- BioCyc:   BAPH198804:BUSG008-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 51350; Mature: 51350

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIATGKIIQIIGAVVDVEFDQNSVPKIYNALEVKNKKIQLILEVQQQLGAGIVRTIAMGS
CCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHCCC
TNGLKRGLIVIDLGHYIKVPVGQATLGRIINVLGKTIDNKGPLKNLDNSKLEYWEIHRSA
CCCCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCC
PSYQEQASSQEILETGIKVIDLICPFSKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGY
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
SVFTGVGERTREGNDFYHEMKDSKVLDKVSLVYGQMNEPPGNRLRVAFTGLTIAEKFRDE
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHC
GRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGLLQERITSTKEGSITSV
CCEEEEEEECHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEE
QAVYVPADDLTDPSPATTFAHLDSTVTLSRQIAALGIYPAIDPLNSTSRQLDPYIVGDEH
EEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEEECCCC
YDTARGVQSILQRYQELKDIIAILGMDELSQEDKILVSRARKIQRFLSQPFFVAEVFTGF
CHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHCC
PGKYVSLKDNIRAFKGIIGGEFDNLPEQAFYMVGTIEEVIKKAKLL
CCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIATGKIIQIIGAVVDVEFDQNSVPKIYNALEVKNKKIQLILEVQQQLGAGIVRTIAMGS
CCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHCCC
TNGLKRGLIVIDLGHYIKVPVGQATLGRIINVLGKTIDNKGPLKNLDNSKLEYWEIHRSA
CCCCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCC
PSYQEQASSQEILETGIKVIDLICPFSKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGY
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
SVFTGVGERTREGNDFYHEMKDSKVLDKVSLVYGQMNEPPGNRLRVAFTGLTIAEKFRDE
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHC
GRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGLLQERITSTKEGSITSV
CCEEEEEEECHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEE
QAVYVPADDLTDPSPATTFAHLDSTVTLSRQIAALGIYPAIDPLNSTSRQLDPYIVGDEH
EEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEEECCCC
YDTARGVQSILQRYQELKDIIAILGMDELSQEDKILVSRARKIQRFLSQPFFVAEVFTGF
CHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHCC
PGKYVSLKDNIRAFKGIIGGEFDNLPEQAFYMVGTIEEVIKKAKLL
CCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9216881; 9516544; 12089438; 7763501