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The map label for this gene is ycgM [C]

Identifier: 21244904

GI number: 21244904

Start: 4924365

End: 4925222

Strand: Direct

Name: ycgM [C]

Synonym: XAC4187

Alternate gene names: 21244904

Gene position: 4924365-4925222 (Clockwise)

Preceding gene: 21244903

Following gene: 21244905

Centisome position: 95.15

GC content: 65.03

Gene sequence:

>858_bases
ATGAAACTCGTACGCATTGGCGCCGAAGGCCACGAACGCCCTGGCCTGATCGATCGCCAAGGCCGCATCCGCGACCTCAG
CGGTGTGATCGACGATGTGGCCGGCGAACACATCACCGCCGCCGGCCTGGAAAAACTGCGCGCACTGGATGTGGCCACGC
TGCCGTTGATCGAAGGCGAGGTGCGTTACGGTGCTGCGGTGGGCCGCATCGGTAAATTCATCTGCGTTGGCTTGAACTAC
GCCGACCACGCCGCCGAATCGGGCATGGAAGTGCCCAAGATGCCGATTCTTTTCATGAAAGCCACCACGGCGGTGTGCGG
CCCCAACGACACGGTGATCATCCCGCGCGGCTCGGTGAAGAGCGACTGGGAAGTGGAGCTGGGCGTGGTGATCGGCGACG
TGGCGCGCGATGTATCGGTGGAGCAAGCGCTGAACCATGTGGCTGGCTACGCCGTGATCAACGACCTGTCCGAGCGCGAA
TTCCAGCTCGAACATGGCGGCCAGTGGGTCAAGGGCAAGAGCGCGGACACCTTCGGCCCGATCGGCCCGTGGCTGGTCAC
CCGCGACGAAATCGCCGACCCGCAGAACCTGTCGATGTGGCTGGAGGTCAACGGCCACCGCTACCAGAACGGCAGCACGC
GCACGATGGTGTTCGGCGTGGCCGAGCTGGTCAGCCACATCAGCCGCTACATGACGCTGATGCCGGGCGATGTGATCAGC
ACCGGTACGCCGCCGGGCGTGGGCCTGGGCCAGAAGCCGCCGGTCTACCTCAAGCCGGGCGATGTGATGGAACTGGAGAT
CGAAGGCCTGGGTCGTCAGCGTCAGCCGGTCGTGGCGCATCCGCGCGATGGGGGTTGA

Upstream 100 bases:

>100_bases
CATGTGCCCGCCTCGAGATGCGCACACCGTCCCTACCCACCCGATGCATGCGCGCTAGGTTTGCTAGCCGCTCCCCTTCT
CATCTGCAAAGGAAGACCGC

Downstream 100 bases:

>100_bases
GGCTTTACGTGTGGAAGAATTGAGGTCGTACTGCAGTGTATTGCGTCCACCTCCAAGAATTTTTCTTGCGCGAAAGCCGA
AGTACTCACGCAACTCGAAT

Product: 2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase/5-carboxymethyl-2-oxo-hex-3-ene-1, 7-dioatedecarboxylase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKLVRIGAEGHERPGLIDRQGRIRDLSGVIDDVAGEHITAAGLEKLRALDVATLPLIEGEVRYGAAVGRIGKFICVGLNY
ADHAAESGMEVPKMPILFMKATTAVCGPNDTVIIPRGSVKSDWEVELGVVIGDVARDVSVEQALNHVAGYAVINDLSERE
FQLEHGGQWVKGKSADTFGPIGPWLVTRDEIADPQNLSMWLEVNGHRYQNGSTRTMVFGVAELVSHISRYMTLMPGDVIS
TGTPPGVGLGQKPPVYLKPGDVMELEIEGLGRQRQPVVAHPRDGG

Sequences:

>Translated_285_residues
MKLVRIGAEGHERPGLIDRQGRIRDLSGVIDDVAGEHITAAGLEKLRALDVATLPLIEGEVRYGAAVGRIGKFICVGLNY
ADHAAESGMEVPKMPILFMKATTAVCGPNDTVIIPRGSVKSDWEVELGVVIGDVARDVSVEQALNHVAGYAVINDLSERE
FQLEHGGQWVKGKSADTFGPIGPWLVTRDEIADPQNLSMWLEVNGHRYQNGSTRTMVFGVAELVSHISRYMTLMPGDVIS
TGTPPGVGLGQKPPVYLKPGDVMELEIEGLGRQRQPVVAHPRDGG
>Mature_285_residues
MKLVRIGAEGHERPGLIDRQGRIRDLSGVIDDVAGEHITAAGLEKLRALDVATLPLIEGEVRYGAAVGRIGKFICVGLNY
ADHAAESGMEVPKMPILFMKATTAVCGPNDTVIIPRGSVKSDWEVELGVVIGDVARDVSVEQALNHVAGYAVINDLSERE
FQLEHGGQWVKGKSADTFGPIGPWLVTRDEIADPQNLSMWLEVNGHRYQNGSTRTMVFGVAELVSHISRYMTLMPGDVIS
TGTPPGVGLGQKPPVYLKPGDVMELEIEGLGRQRQPVVAHPRDGG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=233, Percent_Identity=47.6394849785408, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI40786394, Length=233, Percent_Identity=46.3519313304721, Blast_Score=214, Evalue=7e-56,
Organism=Homo sapiens, GI66348062, Length=213, Percent_Identity=37.5586854460094, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI215422413, Length=203, Percent_Identity=37.9310344827586, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI13654274, Length=201, Percent_Identity=38.3084577114428, Blast_Score=131, Evalue=9e-31,
Organism=Escherichia coli, GI1787428, Length=203, Percent_Identity=36.9458128078818, Blast_Score=134, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17557057, Length=197, Percent_Identity=36.5482233502538, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324161, Length=232, Percent_Identity=31.8965517241379, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28572127, Length=210, Percent_Identity=47.6190476190476, Blast_Score=201, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24663695, Length=277, Percent_Identity=32.8519855595668, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=35.7843137254902, Blast_Score=131, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30715; Mature: 30715

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVRIGAEGHERPGLIDRQGRIRDLSGVIDDVAGEHITAAGLEKLRALDVATLPLIEGE
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHEECCEECCC
VRYGAAVGRIGKFICVGLNYADHAAESGMEVPKMPILFMKATTAVCGPNDTVIIPRGSVK
HHHHHHHHHCCEEEEEECCCHHHHHHCCCCCCCCCEEEEEEEEEEECCCCEEEEECCCCC
SDWEVELGVVIGDVARDVSVEQALNHVAGYAVINDLSEREFQLEHGGQWVKGKSADTFGP
CCCEEEEEEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCC
IGPWLVTRDEIADPQNLSMWLEVNGHRYQNGSTRTMVFGVAELVSHISRYMTLMPGDVIS
CCCEEEEHHHCCCCCCCEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCC
TGTPPGVGLGQKPPVYLKPGDVMELEIEGLGRQRQPVVAHPRDGG
CCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLVRIGAEGHERPGLIDRQGRIRDLSGVIDDVAGEHITAAGLEKLRALDVATLPLIEGE
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHEECCEECCC
VRYGAAVGRIGKFICVGLNYADHAAESGMEVPKMPILFMKATTAVCGPNDTVIIPRGSVK
HHHHHHHHHCCEEEEEECCCHHHHHHCCCCCCCCCEEEEEEEEEEECCCCEEEEECCCCC
SDWEVELGVVIGDVARDVSVEQALNHVAGYAVINDLSEREFQLEHGGQWVKGKSADTFGP
CCCEEEEEEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCC
IGPWLVTRDEIADPQNLSMWLEVNGHRYQNGSTRTMVFGVAELVSHISRYMTLMPGDVIS
CCCEEEEHHHCCCCCCCEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCC
TGTPPGVGLGQKPPVYLKPGDVMELEIEGLGRQRQPVVAHPRDGG
CCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA