Click here to switch to the map view.

The map label for this gene is dsbC [H]

Identifier: 21244275

GI number: 21244275

Start: 4209358

End: 4210161

Strand: Reverse

Name: dsbC [H]

Synonym: XAC3550

Alternate gene names: 21244275

Gene position: 4210161-4209358 (Counterclockwise)

Preceding gene: 161485706

Following gene: 21244274

Centisome position: 81.35

GC content: 67.04

Gene sequence:

>804_bases
ATGTATCGTCTTGCCATCGCCGCGCTGCTGGGCGCGATCAGCCTTACCGCCTGCGCACAATCCTCGCAGCCTGCGGCAAG
CACTGCCGGCGCCAAGCCAGCCGCTGCGCCCGCCGCCACCGGCACCGGCACCGTGGACCAGCGCGTGAGCACGGCGCTCA
AGGCGCTGGACCCGGATTTCAAACCCGATTACATCGGCGCTGCGCCGTTCCCCGGCTTTCGCGAAGTGGTCGTCGGCGGG
CAGGTGCTGTACGTCAGCGACGACGGTCGTTACCTGATCCAGGCGCAGCCGTTCGACATCCAGAACAAGCAGTTCGCCGC
CAGCCCGGGCTTGCTGGCCTACCGCCGCAAGCAGCTGGACACCGTGCCCAAGGCCGACCGCATCGTGTTCGCGCCGGCCA
ACCCGAAGTACACCGTCACCGTCTTCACCGATGTGGAGTGCGGTTACTGCCGTAAGTTGCATAGCGAGATCGGCGAGCTC
AACAAGCAGGGCATCGCGGTGGAATACCTGGCGTTCCCGCGCATGGGCCTGGGCAGCCAGGACCATAAGGAAATGATTGC
GGTGTGGTGCGCTGCCGATCGCAAGCAGGCGCTCACGGCCGCCAAGTCGGGTCAGCCGGTCGCCTCCAAGGACTGCAAGA
ACCCGGTGTCGATGGAATACAACCTGGGCCAGCGCCTGGGCGTCAACGGAACGCCGGCGATCTTCGCCCCCGACGGCACC
CAGCTCGGTGGCTACCTGCCGCCAGCCCAGTTGCGTGAGGCGCTGGAAAAGCGTGCCGTGAGCACGGCGGGCGGCAGCCG
CTGA

Upstream 100 bases:

>100_bases
CAACGGGGTGCCTGCAGCGCTCACAAACTGTCGCGGCCGCGGCCAGGCTTCATCTGCGCTGTGCGAGAATCCCGGCACCT
CATTCCATCTGGATGCGTGA

Downstream 100 bases:

>100_bases
GGCCGTCTCGGCTCTGATCATCGTGGCGCGTCGCCGATAGCGCCGTTGCGTTGATCGTCTGCGCAACGACAAGGCCCGGG
TCCGACTGCATCCGGGCCTT

Product: disulfide isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MYRLAIAALLGAISLTACAQSSQPAASTAGAKPAAAPAATGTGTVDQRVSTALKALDPDFKPDYIGAAPFPGFREVVVGG
QVLYVSDDGRYLIQAQPFDIQNKQFAASPGLLAYRRKQLDTVPKADRIVFAPANPKYTVTVFTDVECGYCRKLHSEIGEL
NKQGIAVEYLAFPRMGLGSQDHKEMIAVWCAADRKQALTAAKSGQPVASKDCKNPVSMEYNLGQRLGVNGTPAIFAPDGT
QLGGYLPPAQLREALEKRAVSTAGGSR

Sequences:

>Translated_267_residues
MYRLAIAALLGAISLTACAQSSQPAASTAGAKPAAAPAATGTGTVDQRVSTALKALDPDFKPDYIGAAPFPGFREVVVGG
QVLYVSDDGRYLIQAQPFDIQNKQFAASPGLLAYRRKQLDTVPKADRIVFAPANPKYTVTVFTDVECGYCRKLHSEIGEL
NKQGIAVEYLAFPRMGLGSQDHKEMIAVWCAADRKQALTAAKSGQPVASKDCKNPVSMEYNLGQRLGVNGTPAIFAPDGT
QLGGYLPPAQLREALEKRAVSTAGGSR
>Mature_267_residues
MYRLAIAALLGAISLTACAQSSQPAASTAGAKPAAAPAATGTGTVDQRVSTALKALDPDFKPDYIGAAPFPGFREVVVGG
QVLYVSDDGRYLIQAQPFDIQNKQFAASPGLLAYRRKQLDTVPKADRIVFAPANPKYTVTVFTDVECGYCRKLHSEIGEL
NKQGIAVEYLAFPRMGLGSQDHKEMIAVWCAADRKQALTAAKSGQPVASKDCKNPVSMEYNLGQRLGVNGTPAIFAPDGT
QLGGYLPPAQLREALEKRAVSTAGGSR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=207, Percent_Identity=39.1304347826087, Blast_Score=162, Evalue=2e-41,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 28262; Mature: 28262

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRLAIAALLGAISLTACAQSSQPAASTAGAKPAAAPAATGTGTVDQRVSTALKALDPDF
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
KPDYIGAAPFPGFREVVVGGQVLYVSDDGRYLIQAQPFDIQNKQFAASPGLLAYRRKQLD
CCCCCCCCCCCCHHHHEECCEEEEEECCCCEEEEECCCCCCCCEECCCCCHHHHHHHHHC
TVPKADRIVFAPANPKYTVTVFTDVECGYCRKLHSEIGELNKQGIAVEYLAFPRMGLGSQ
CCCCCCEEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC
DHKEMIAVWCAADRKQALTAAKSGQPVASKDCKNPVSMEYNLGQRLGVNGTPAIFAPDGT
HHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCCCCCEEECCCCCCCCCCCCEEECCCCC
QLGGYLPPAQLREALEKRAVSTAGGSR
CCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYRLAIAALLGAISLTACAQSSQPAASTAGAKPAAAPAATGTGTVDQRVSTALKALDPDF
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
KPDYIGAAPFPGFREVVVGGQVLYVSDDGRYLIQAQPFDIQNKQFAASPGLLAYRRKQLD
CCCCCCCCCCCCHHHHEECCEEEEEECCCCEEEEECCCCCCCCEECCCCCHHHHHHHHHC
TVPKADRIVFAPANPKYTVTVFTDVECGYCRKLHSEIGELNKQGIAVEYLAFPRMGLGSQ
CCCCCCEEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC
DHKEMIAVWCAADRKQALTAAKSGQPVASKDCKNPVSMEYNLGQRLGVNGTPAIFAPDGT
HHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCCCCCEEECCCCCCCCCCCCEEECCCCC
QLGGYLPPAQLREALEKRAVSTAGGSR
CCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]