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The map label for this gene is purL

Identifier: 21244274

GI number: 21244274

Start: 4204772

End: 4208818

Strand: Reverse

Name: purL

Synonym: XAC3549

Alternate gene names: 21244274

Gene position: 4208818-4204772 (Counterclockwise)

Preceding gene: 21244275

Following gene: 77748727

Centisome position: 81.32

GC content: 68.32

Gene sequence:

>4047_bases
ATGATGGTCCTCGAGGGCGCTTCCGCCCTTTCGCCGTTCCGCCGCGCTCGGCTCGAAACCCGCCTGCAAACCCTCGTTCC
CGCGCTGCGTATCACTGGCGCCTGGCACGTGTACTTCATCCGTCCCGAGGCCGGGCAATCGCCCGACCAGGCCACCTTGC
AGCGGATCCTGCAGGCCAACGCCGCGCCCGCCGAGCGCGATGCCGATGCCTCCTCGCGCTACGTGGTGCCGCGCCTGGGC
ACCTTGTCGCCGTGGTCGAGCAAGGCCACCGAACTGGTGCGCGGGGCTGGGCAGCCGATCCAGCGCGTGGAGCGCGGCAC
CCGCATCGATCTGGCCGGCTGGCCGGACGACGCGTCCGCCCAGGCCGCCGTGGCCAAGTTGCTGCACGACCCGATGACGC
AATCGCTGCTCGGTTCGGCCGCCGCTGCCGAAGCGCTGTTCAACGTGCCCGACCCGGGCCAGCTGCGGCGCGTGCCGCTG
GATGGGCTGGAGCAGGCCAACCGCGACCTGGGCCTGGCCCTGGCGCAGGACGAGATCGACTACCTGCGCGAACGTTTCGG
CGCGCTGGGCCGCGACCCGGCCGACGTCGAGCTGATGATGTTCGCCCAGGCCAACTCCGAGCATTGCCGGCACAAGATCT
TCAATGCCACCTGGACCATCGACGGCAAGCCGCAGGAGCGCTCGCTGTTCCGCATGATCAAGCACACCCACCAGCAGACC
CCGCAGCACACCTTGTCGGCCTACAGCGACAACGCGGCGGTGGTGGAAGGCGTGCCGGCTGCGCGCTATCGCCCGGATCC
GGCCACCGGCCAATACCGCAGCGAAGCGGTGCTGCCGTCGGCGTTTGCGATCAAGGTGGAAACGCATAACCACCCGACCG
CGATCGCACCGTTCCCCGGCGCGGCCACCGGTGCGGGCGGCGAAATTCGCGACGAAGGCGCCACTGGGCGCGGCGGCAAG
CCCAAGGCCGGCCTGACCGGGTTTTCGGTCTCGCACCTGCGCATTCCGACCCTGCCGCAGCCCTGGGAAGCGCCGCGCGC
GCTGAACCCGCGCATGGCGCCGGCGCTGGACATCATGCTCGACGGCCCTCTCGGCGGCGCAGCGTTCAACAACGAATTCG
GCCGGCCGAACCTGCTCGGCTATTTCCGCAGCTTCGAGCTTGCCGAAGGCCCGGGCCTGACCCGCGCCTACGACAAGCCG
ATCATGCTGGCCGGTGGCCTGGGCGCGATCGACCGCAACCAGGTGGAAAAGCTGCGCCTGCAGCCGGGCGATGCGGTGAT
CGTGCTCGGCGGCCCGGCGATGCTGATCGGCCTGGGCGGCGGTGCGGCCAGTTCGGTGGCGGCCGGCGACAGCGCCGAGG
CACTGGATTTCGCCAGCGTGCAACGCGAAAACCCGGAAATGGAACGTCGCTGCCAGGAGGTCATCGACCGCTGCGTGGCG
CTGGGCGTGGACAACCCGATCCGCTGGTTCCACGACGTGGGCGCGGGTGGTTTGTCCAACGCCATCCCCGAGCTGCTGCA
CGATTCGGGCGTGGGCGGCATCATCGACCTGGGCCGCGTGCTCACCGACGACCCGTCGCTGTCGCCGCTGGAACTGTGGT
GCAACGAATCGCAGGAGCGCTACGTGCTCGGCGTGCCGCAGGCGCGCCTTGAAGAATTCGCCGCCATCTGCGCCCGCGAA
CGCTGCCCGTTCGCCGCCGTCGGCGTGGCGACGGCCGAGGAGCGGCTGGTGGTGGGCTATGGCGTCCTGGACGCCGGGAA
TCGGGAATCGGGAGTCGGGAATCGTAACGGCACGCTTGTGGCTGCCGACACCGCTTCACACCATTCCCCATTCCCGACTC
GCGATTCCCAGCTCCCGATCGATCTGCCCATGGACGTGCTGTTCGGCAAGGCGCCGAAGATGCATCGCGATGCGGCGCAT
CCGGGTGCGCCGCAATGGCCGGTGCTGCAGACCGCGTCGCTGGACCTGCAGCAGGCGGGCCTGCGCGTGTTGGCGCATCC
CACCGTGGCGTCCAAGAGCTTTCTGGTCACCATCGGCGATCGCAGCGTTGGCGGTCTGACCGCACGCGAACAGATGATCG
GTCCGTGGCAGCTGCCGCTGGCCGATTGCGCGATCACGCTGGCCGGTTTCGATACCTTCGAAGGCGAAGCGATGTCGATC
GGCGAGCGCACGCCGCTGGCGCTGTTGAATGCCGCCGCATCTGCGCGCATGGCCGTGGGCGAAGCGATCACCAACCTGTG
CGCCGCACCGGTGCAGACGCTGGACAGCATCAAGCTCTCGGCCAACTGGATGGCCGCCGCCGGCCATAGCGGCGAAGACG
CGTTGCTGTACGACGCCGTGCGCGCGATCGGCATGGAGCTGTGCCCGGCACTCGAACTGAGCGTGCCGGTGGGCAAGGAT
TCGCTGTCGATGCAGGCGCAGTGGCAGGTCGGGAATCGGGAATCGGGAATCGGGAATGGTGAAACGCCTCAGCCCTCCGC
TTCCACCATTCCCGATTCTCCATTCCCTATTCCCGGTGAAACGCTGAAAAGCGTTTCGCCGGTCTCGTTGATCATCAGTG
CGTTCGCCCCGGTTGGCGATGTGCGCACGCAGCTGACGCCGTTGCTGCGCAGCGGTGAAGAGAGCGAGTTGTGGTTGATC
GGGCTGGGAGGCGGCAAGCAGCGGCTGGGCGGGTCGGTGCTGGCGCAGGTGTATGCCGACGACACCGCGCTGCCGGCGTT
CGGCGGCGAGGTGCCGGATCTGGACGATGCGCAGCGGCTGCGCAGCTTCTTCGAATTGATTCGCGACGCGCGCGACAGCG
GGCTGTTGCTGGCGTATCACGATCGCAGCGATGGCGGTGCGTTTGCTGCGCTGTGCGAGATGGCGTTTGCGTCGCGGCAG
GGCCTGGATATCACGCTGGATGCATGGGGCGACGATGCGTTCCGCAGCCTGTTCAACGAAGAATTGGGCGCAGTGGTGCA
GATCGCCAGCGAAGACCGCGCCGCGTTCGCCGACCTGGTCGAGCGCCACGCATTGACCGAATGCGCGCAGCGCATTGCAC
GCCCCACCGGCACGCCGCGCATCCGCGTGAGCGGGCAGGGCCGCGTGCTGGCCGAATGGCGCTGGGAAGAGCTGTTCGAT
GCGTGGTGGTCGGTGACCCATGCGATGCAGAAGCTGCGCGACAACCCGGACAGCGCCGATGAAGAACGCGCCCTGGCGCG
TGATTTCAAGGCGTCAGGCCTGCGCCCGAAGCTGGTGTTCGACCCTTCCGACGATGTCGCGGCGCCATTCGTGGCCACCG
GCACGCGGCCCAAGGTGGCGATCCTGCGCGAGCAGGGCGTCAACGGGCAGATCGAAATGGCCTACAACTTCGAGCGTGCC
GGTTTCCGTCCCTACGACGTGCACATGAGCGACCTGATCGAGGGCCGCGTGGACCTGAGCGCGTTCGTGGGCTTTGCGGC
GTGCGGCGGTTTCAGCTACGGCGACGTGCTGGGTGCAGGCCGCGGCTGGGCGACATCCATCCTGGAGCGCTCGGCGCTGC
GCGACGCGTTCGCCGCGTTCTTCGCACGCAGCGATACGTTCGCGCTGGGCGTGTGCAACGGATGCCAGATGCTCAGCCAG
CTCAAGGACATCATTCCCGGTGCCGAGCATTGGCCGCGCTTCCTGCGTAATCGCAGCGAGCAGTTCGAAGCGCGCACCGC
GCTGCTGGAAGTGGTGGAGTCGCCGTCGATCTTCCTGCGCGGCATGGCCGGCTCGCGGATTCCGGTGGCGGTTGCGCATG
GCGAAGGCCGCGCAGAGTTCGATAGCGCCGTGGACCAGGCCGCCGCACGCGTGGCATTGCGTTACATCGATGGCGACGGC
GCGGTGGCGTCGCAGTATCCGCTCAATCCGAACGGTTCCCCCGACGGCATCACCGGGCTGACCAGCAGCGACGGCCGCGT
CACCATCCTGATGCCGCATCCGGAGCGCACGCCACGCAGCGCAAACCTGAGCTGGTACCCGGTCGACTGGGGCGACGACT
CGCCGTGGCTGCGGATGTTCCGCAACGCGCGGGTGTGGTGCGGTTGA

Upstream 100 bases:

>100_bases
GATTCCCATTCCCGAGTCCCGCCATCGCACGCGCAGTCCGGCGTCGATTCATCAGCTCCGTTACAATCTGCAGCCCCGTT
TCTGACACGGTTCCCCGGAC

Downstream 100 bases:

>100_bases
TGCCGTGCGGCTGATCGGCAGCCGCTGACGCATGACCCGACGGCCGTGTGCAGCGATGCACACGGCCGTTGTCGTTTAGG
CCGGCGCGCTGAATCTGCAA

Product: phosphoribosylformylglycinamidine synthase

Products: NA

Alternate protein names: FGAM synthase; FGAMS; Formylglycinamide ribotide amidotransferase; FGARAT; Formylglycinamide ribotide synthetase

Number of amino acids: Translated: 1348; Mature: 1348

Protein sequence:

>1348_residues
MMVLEGASALSPFRRARLETRLQTLVPALRITGAWHVYFIRPEAGQSPDQATLQRILQANAAPAERDADASSRYVVPRLG
TLSPWSSKATELVRGAGQPIQRVERGTRIDLAGWPDDASAQAAVAKLLHDPMTQSLLGSAAAAEALFNVPDPGQLRRVPL
DGLEQANRDLGLALAQDEIDYLRERFGALGRDPADVELMMFAQANSEHCRHKIFNATWTIDGKPQERSLFRMIKHTHQQT
PQHTLSAYSDNAAVVEGVPAARYRPDPATGQYRSEAVLPSAFAIKVETHNHPTAIAPFPGAATGAGGEIRDEGATGRGGK
PKAGLTGFSVSHLRIPTLPQPWEAPRALNPRMAPALDIMLDGPLGGAAFNNEFGRPNLLGYFRSFELAEGPGLTRAYDKP
IMLAGGLGAIDRNQVEKLRLQPGDAVIVLGGPAMLIGLGGGAASSVAAGDSAEALDFASVQRENPEMERRCQEVIDRCVA
LGVDNPIRWFHDVGAGGLSNAIPELLHDSGVGGIIDLGRVLTDDPSLSPLELWCNESQERYVLGVPQARLEEFAAICARE
RCPFAAVGVATAEERLVVGYGVLDAGNRESGVGNRNGTLVAADTASHHSPFPTRDSQLPIDLPMDVLFGKAPKMHRDAAH
PGAPQWPVLQTASLDLQQAGLRVLAHPTVASKSFLVTIGDRSVGGLTAREQMIGPWQLPLADCAITLAGFDTFEGEAMSI
GERTPLALLNAAASARMAVGEAITNLCAAPVQTLDSIKLSANWMAAAGHSGEDALLYDAVRAIGMELCPALELSVPVGKD
SLSMQAQWQVGNRESGIGNGETPQPSASTIPDSPFPIPGETLKSVSPVSLIISAFAPVGDVRTQLTPLLRSGEESELWLI
GLGGGKQRLGGSVLAQVYADDTALPAFGGEVPDLDDAQRLRSFFELIRDARDSGLLLAYHDRSDGGAFAALCEMAFASRQ
GLDITLDAWGDDAFRSLFNEELGAVVQIASEDRAAFADLVERHALTECAQRIARPTGTPRIRVSGQGRVLAEWRWEELFD
AWWSVTHAMQKLRDNPDSADEERALARDFKASGLRPKLVFDPSDDVAAPFVATGTRPKVAILREQGVNGQIEMAYNFERA
GFRPYDVHMSDLIEGRVDLSAFVGFAACGGFSYGDVLGAGRGWATSILERSALRDAFAAFFARSDTFALGVCNGCQMLSQ
LKDIIPGAEHWPRFLRNRSEQFEARTALLEVVESPSIFLRGMAGSRIPVAVAHGEGRAEFDSAVDQAAARVALRYIDGDG
AVASQYPLNPNGSPDGITGLTSSDGRVTILMPHPERTPRSANLSWYPVDWGDDSPWLRMFRNARVWCG

Sequences:

>Translated_1348_residues
MMVLEGASALSPFRRARLETRLQTLVPALRITGAWHVYFIRPEAGQSPDQATLQRILQANAAPAERDADASSRYVVPRLG
TLSPWSSKATELVRGAGQPIQRVERGTRIDLAGWPDDASAQAAVAKLLHDPMTQSLLGSAAAAEALFNVPDPGQLRRVPL
DGLEQANRDLGLALAQDEIDYLRERFGALGRDPADVELMMFAQANSEHCRHKIFNATWTIDGKPQERSLFRMIKHTHQQT
PQHTLSAYSDNAAVVEGVPAARYRPDPATGQYRSEAVLPSAFAIKVETHNHPTAIAPFPGAATGAGGEIRDEGATGRGGK
PKAGLTGFSVSHLRIPTLPQPWEAPRALNPRMAPALDIMLDGPLGGAAFNNEFGRPNLLGYFRSFELAEGPGLTRAYDKP
IMLAGGLGAIDRNQVEKLRLQPGDAVIVLGGPAMLIGLGGGAASSVAAGDSAEALDFASVQRENPEMERRCQEVIDRCVA
LGVDNPIRWFHDVGAGGLSNAIPELLHDSGVGGIIDLGRVLTDDPSLSPLELWCNESQERYVLGVPQARLEEFAAICARE
RCPFAAVGVATAEERLVVGYGVLDAGNRESGVGNRNGTLVAADTASHHSPFPTRDSQLPIDLPMDVLFGKAPKMHRDAAH
PGAPQWPVLQTASLDLQQAGLRVLAHPTVASKSFLVTIGDRSVGGLTAREQMIGPWQLPLADCAITLAGFDTFEGEAMSI
GERTPLALLNAAASARMAVGEAITNLCAAPVQTLDSIKLSANWMAAAGHSGEDALLYDAVRAIGMELCPALELSVPVGKD
SLSMQAQWQVGNRESGIGNGETPQPSASTIPDSPFPIPGETLKSVSPVSLIISAFAPVGDVRTQLTPLLRSGEESELWLI
GLGGGKQRLGGSVLAQVYADDTALPAFGGEVPDLDDAQRLRSFFELIRDARDSGLLLAYHDRSDGGAFAALCEMAFASRQ
GLDITLDAWGDDAFRSLFNEELGAVVQIASEDRAAFADLVERHALTECAQRIARPTGTPRIRVSGQGRVLAEWRWEELFD
AWWSVTHAMQKLRDNPDSADEERALARDFKASGLRPKLVFDPSDDVAAPFVATGTRPKVAILREQGVNGQIEMAYNFERA
GFRPYDVHMSDLIEGRVDLSAFVGFAACGGFSYGDVLGAGRGWATSILERSALRDAFAAFFARSDTFALGVCNGCQMLSQ
LKDIIPGAEHWPRFLRNRSEQFEARTALLEVVESPSIFLRGMAGSRIPVAVAHGEGRAEFDSAVDQAAARVALRYIDGDG
AVASQYPLNPNGSPDGITGLTSSDGRVTILMPHPERTPRSANLSWYPVDWGDDSPWLRMFRNARVWCG
>Mature_1348_residues
MMVLEGASALSPFRRARLETRLQTLVPALRITGAWHVYFIRPEAGQSPDQATLQRILQANAAPAERDADASSRYVVPRLG
TLSPWSSKATELVRGAGQPIQRVERGTRIDLAGWPDDASAQAAVAKLLHDPMTQSLLGSAAAAEALFNVPDPGQLRRVPL
DGLEQANRDLGLALAQDEIDYLRERFGALGRDPADVELMMFAQANSEHCRHKIFNATWTIDGKPQERSLFRMIKHTHQQT
PQHTLSAYSDNAAVVEGVPAARYRPDPATGQYRSEAVLPSAFAIKVETHNHPTAIAPFPGAATGAGGEIRDEGATGRGGK
PKAGLTGFSVSHLRIPTLPQPWEAPRALNPRMAPALDIMLDGPLGGAAFNNEFGRPNLLGYFRSFELAEGPGLTRAYDKP
IMLAGGLGAIDRNQVEKLRLQPGDAVIVLGGPAMLIGLGGGAASSVAAGDSAEALDFASVQRENPEMERRCQEVIDRCVA
LGVDNPIRWFHDVGAGGLSNAIPELLHDSGVGGIIDLGRVLTDDPSLSPLELWCNESQERYVLGVPQARLEEFAAICARE
RCPFAAVGVATAEERLVVGYGVLDAGNRESGVGNRNGTLVAADTASHHSPFPTRDSQLPIDLPMDVLFGKAPKMHRDAAH
PGAPQWPVLQTASLDLQQAGLRVLAHPTVASKSFLVTIGDRSVGGLTAREQMIGPWQLPLADCAITLAGFDTFEGEAMSI
GERTPLALLNAAASARMAVGEAITNLCAAPVQTLDSIKLSANWMAAAGHSGEDALLYDAVRAIGMELCPALELSVPVGKD
SLSMQAQWQVGNRESGIGNGETPQPSASTIPDSPFPIPGETLKSVSPVSLIISAFAPVGDVRTQLTPLLRSGEESELWLI
GLGGGKQRLGGSVLAQVYADDTALPAFGGEVPDLDDAQRLRSFFELIRDARDSGLLLAYHDRSDGGAFAALCEMAFASRQ
GLDITLDAWGDDAFRSLFNEELGAVVQIASEDRAAFADLVERHALTECAQRIARPTGTPRIRVSGQGRVLAEWRWEELFD
AWWSVTHAMQKLRDNPDSADEERALARDFKASGLRPKLVFDPSDDVAAPFVATGTRPKVAILREQGVNGQIEMAYNFERA
GFRPYDVHMSDLIEGRVDLSAFVGFAACGGFSYGDVLGAGRGWATSILERSALRDAFAAFFARSDTFALGVCNGCQMLSQ
LKDIIPGAEHWPRFLRNRSEQFEARTALLEVVESPSIFLRGMAGSRIPVAVAHGEGRAEFDSAVDQAAARVALRYIDGDG
AVASQYPLNPNGSPDGITGLTSSDGRVTILMPHPERTPRSANLSWYPVDWGDDSPWLRMFRNARVWCG

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Homo sapiens, GI31657129, Length=1311, Percent_Identity=36.6895499618612, Blast_Score=669, Evalue=0.0,
Organism=Escherichia coli, GI48994899, Length=1366, Percent_Identity=51.9765739385066, Blast_Score=1304, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17553022, Length=1355, Percent_Identity=32.0295202952029, Blast_Score=581, Evalue=1e-166,
Organism=Saccharomyces cerevisiae, GI6321498, Length=1330, Percent_Identity=47.5187969924812, Blast_Score=1130, Evalue=0.0,
Organism=Drosophila melanogaster, GI24582111, Length=1324, Percent_Identity=35.1208459214501, Blast_Score=647, Evalue=0.0,
Organism=Drosophila melanogaster, GI24582109, Length=1324, Percent_Identity=35.1208459214501, Blast_Score=647, Evalue=0.0,
Organism=Drosophila melanogaster, GI17137292, Length=1324, Percent_Identity=35.1208459214501, Blast_Score=647, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PUR4_XANAC (Q8PGR7)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643856.1
- ProteinModelPortal:   Q8PGR7
- GeneID:   1157620
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC3549
- NMPDR:   fig|190486.1.peg.3500
- HOGENOM:   HBG335309
- OMA:   ERGIAYY
- ProtClustDB:   PRK05297
- BioCyc:   XAXO190486:XAC3549-MONOMER
- BRENDA:   6.3.5.3
- GO:   GO:0005737
- HAMAP:   MF_00419
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR017926
- InterPro:   IPR010073
- InterPro:   IPR022940
- InterPro:   IPR016188
- TIGRFAMs:   TIGR01735

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =6.3.5.3

Molecular weight: Translated: 144663; Mature: 144663

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 1192-1192 ACT_SITE 1313-1313 ACT_SITE 1315-1315

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVLEGASALSPFRRARLETRLQTLVPALRITGAWHVYFIRPEAGQSPDQATLQRILQAN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHCC
AAPAERDADASSRYVVPRLGTLSPWSSKATELVRGAGQPIQRVERGTRIDLAGWPDDASA
CCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCEEEECCCCCCCHH
QAAVAKLLHDPMTQSLLGSAAAAEALFNVPDPGQLRRVPLDGLEQANRDLGLALAQDEID
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHCCCCCCEEEHHHHHH
YLRERFGALGRDPADVELMMFAQANSEHCRHKIFNATWTIDGKPQERSLFRMIKHTHQQT
HHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCC
PQHTLSAYSDNAAVVEGVPAARYRPDPATGQYRSEAVLPSAFAIKVETHNHPTAIAPFPG
HHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEECCCCC
AATGAGGEIRDEGATGRGGKPKAGLTGFSVSHLRIPTLPQPWEAPRALNPRMAPALDIML
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECEEECCCCCCCCCCCCCCCCCCCCEEEEEE
DGPLGGAAFNNEFGRPNLLGYFRSFELAEGPGLTRAYDKPIMLAGGLGAIDRNQVEKLRL
ECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHEE
QPGDAVIVLGGPAMLIGLGGGAASSVAAGDSAEALDFASVQRENPEMERRCQEVIDRCVA
CCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGVDNPIRWFHDVGAGGLSNAIPELLHDSGVGGIIDLGRVLTDDPSLSPLELWCNESQER
HCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCE
YVLGVPQARLEEFAAICARERCPFAAVGVATAEERLVVGYGVLDAGNRESGVGNRNGTLV
EEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCEEE
AADTASHHSPFPTRDSQLPIDLPMDVLFGKAPKMHRDAAHPGAPQWPVLQTASLDLQQAG
EECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHCCCCCCCCCCCCCEECCCCCHHHCC
LRVLAHPTVASKSFLVTIGDRSVGGLTAREQMIGPWQLPLADCAITLAGFDTFEGEAMSI
CEEEECCCCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCHHHHEEEEECCCCCCCCEEEC
GERTPLALLNAAASARMAVGEAITNLCAAPVQTLDSIKLSANWMAAAGHSGEDALLYDAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCHHHHHHH
RAIGMELCPALELSVPVGKDSLSMQAQWQVGNRESGIGNGETPQPSASTIPDSPFPIPGE
HHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
TLKSVSPVSLIISAFAPVGDVRTQLTPLLRSGEESELWLIGLGGGKQRLGGSVLAQVYAD
HHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHCHHHHHHHHHC
DTALPAFGGEVPDLDDAQRLRSFFELIRDARDSGLLLAYHDRSDGGAFAALCEMAFASRQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCC
GLDITLDAWGDDAFRSLFNEELGAVVQIASEDRAAFADLVERHALTECAQRIARPTGTPR
CCEEEEECCCCHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
IRVSGQGRVLAEWRWEELFDAWWSVTHAMQKLRDNPDSADEERALARDFKASGLRPKLVF
EEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEE
DPSDDVAAPFVATGTRPKVAILREQGVNGQIEMAYNFERAGFRPYDVHMSDLIEGRVDLS
CCCCCCCCCEEECCCCCEEEEEEECCCCCEEEEEEEHHHCCCCEEECCHHHHHCCCHHHH
AFVGFAACGGFSYGDVLGAGRGWATSILERSALRDAFAAFFARSDTFALGVCNGCQMLSQ
HHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH
LKDIIPGAEHWPRFLRNRSEQFEARTALLEVVESPSIFLRGMAGSRIPVAVAHGEGRAEF
HHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCHHH
DSAVDQAAARVALRYIDGDGAVASQYPLNPNGSPDGITGLTSSDGRVTILMPHPERTPRS
HHHHHHHHHHEEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
ANLSWYPVDWGDDSPWLRMFRNARVWCG
CCCEEEECCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MMVLEGASALSPFRRARLETRLQTLVPALRITGAWHVYFIRPEAGQSPDQATLQRILQAN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHCC
AAPAERDADASSRYVVPRLGTLSPWSSKATELVRGAGQPIQRVERGTRIDLAGWPDDASA
CCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCEEEECCCCCCCHH
QAAVAKLLHDPMTQSLLGSAAAAEALFNVPDPGQLRRVPLDGLEQANRDLGLALAQDEID
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHCCCCCCEEEHHHHHH
YLRERFGALGRDPADVELMMFAQANSEHCRHKIFNATWTIDGKPQERSLFRMIKHTHQQT
HHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCC
PQHTLSAYSDNAAVVEGVPAARYRPDPATGQYRSEAVLPSAFAIKVETHNHPTAIAPFPG
HHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEECCCCC
AATGAGGEIRDEGATGRGGKPKAGLTGFSVSHLRIPTLPQPWEAPRALNPRMAPALDIML
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECEEECCCCCCCCCCCCCCCCCCCCEEEEEE
DGPLGGAAFNNEFGRPNLLGYFRSFELAEGPGLTRAYDKPIMLAGGLGAIDRNQVEKLRL
ECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHEE
QPGDAVIVLGGPAMLIGLGGGAASSVAAGDSAEALDFASVQRENPEMERRCQEVIDRCVA
CCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGVDNPIRWFHDVGAGGLSNAIPELLHDSGVGGIIDLGRVLTDDPSLSPLELWCNESQER
HCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCE
YVLGVPQARLEEFAAICARERCPFAAVGVATAEERLVVGYGVLDAGNRESGVGNRNGTLV
EEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCEEE
AADTASHHSPFPTRDSQLPIDLPMDVLFGKAPKMHRDAAHPGAPQWPVLQTASLDLQQAG
EECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHCCCCCCCCCCCCCEECCCCCHHHCC
LRVLAHPTVASKSFLVTIGDRSVGGLTAREQMIGPWQLPLADCAITLAGFDTFEGEAMSI
CEEEECCCCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCHHHHEEEEECCCCCCCCEEEC
GERTPLALLNAAASARMAVGEAITNLCAAPVQTLDSIKLSANWMAAAGHSGEDALLYDAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCHHHHHHH
RAIGMELCPALELSVPVGKDSLSMQAQWQVGNRESGIGNGETPQPSASTIPDSPFPIPGE
HHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
TLKSVSPVSLIISAFAPVGDVRTQLTPLLRSGEESELWLIGLGGGKQRLGGSVLAQVYAD
HHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHCHHHHHHHHHC
DTALPAFGGEVPDLDDAQRLRSFFELIRDARDSGLLLAYHDRSDGGAFAALCEMAFASRQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCC
GLDITLDAWGDDAFRSLFNEELGAVVQIASEDRAAFADLVERHALTECAQRIARPTGTPR
CCEEEEECCCCHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
IRVSGQGRVLAEWRWEELFDAWWSVTHAMQKLRDNPDSADEERALARDFKASGLRPKLVF
EEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEE
DPSDDVAAPFVATGTRPKVAILREQGVNGQIEMAYNFERAGFRPYDVHMSDLIEGRVDLS
CCCCCCCCCEEECCCCCEEEEEEECCCCCEEEEEEEHHHCCCCEEECCHHHHHCCCHHHH
AFVGFAACGGFSYGDVLGAGRGWATSILERSALRDAFAAFFARSDTFALGVCNGCQMLSQ
HHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH
LKDIIPGAEHWPRFLRNRSEQFEARTALLEVVESPSIFLRGMAGSRIPVAVAHGEGRAEF
HHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCHHH
DSAVDQAAARVALRYIDGDGAVASQYPLNPNGSPDGITGLTSSDGRVTILMPHPERTPRS
HHHHHHHHHHEEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
ANLSWYPVDWGDDSPWLRMFRNARVWCG
CCCEEEECCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217