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The map label for this gene is fhuE [H]

Identifier: 21244223

GI number: 21244223

Start: 4135593

End: 4137788

Strand: Reverse

Name: fhuE [H]

Synonym: XAC3498

Alternate gene names: 21244223

Gene position: 4137788-4135593 (Counterclockwise)

Preceding gene: 77748721

Following gene: 21244218

Centisome position: 79.95

GC content: 65.85

Gene sequence:

>2196_bases
ATGTCCCATCGTATCGTCCCTGCGCGCGCGCTGACGCGTGCGGATATCCGTTCGCCGCAGCTCCCGCTGGCGTACTCCCT
GCTTGCGCTTGCGCTGGCCTGCGCATGGCCATTGGCGGCTGCGGCGCAATCGAGCACGCGCGACCCGGTCGATCTGGACC
GCCTGCAGATCGAGGCACACCGCGGCGCCGCGACCGAAGGCAGCGACTCCTACACCGCCGATGTGGCGCGCAGTTCGACC
AAGCTGGAGCTGTCGCTGCGCGAGACGCCGCAGTCGGTGGTGGTGGTGACCCGCCAGCAGATCGTCGACCGTAACCTGCA
ATCGCTGCAGGACGTCACCGACACCGTGGCCGGCTTCAACTCGCCGACCTGGGACACCGAGCGCACCTACATCACTGCGC
GCGGCTTCGAAGTGGACTACTACCGCATCGACGGCATTCCCACCGACTACACCGGCGACGTGCAGCAGAACATGGCGATC
TACGACCGGGTGGAAATCATCCGCGGCGCCAACGGCCTGACCACCGGCGCGGGCAGTCCGGCCGCGTCGATCGACCTGGT
GCGCAAGCATGCCGACAGCGATGTGTTCACCGGTCGGGTCGATCTGTCGGCAGGGCGTTGGGACCGCTATCGCGGCACCG
TCGACCTGCAATCGCCCTTGAACGCCGCCGGCAACGTGCGTGGACGGGTGGTTGCCAGTGACGAGGACAAGCAGTCGTTC
CGCGATTACTACAGCAAGCAATCGTCGCTGTTCTACGGCATCGTCGATGCGGATTTCAGCGATGCCACCCGCGGCTACAT
CGGCGTCAACAAGCAGCGCAACGACGGCCGCGGCACCACCTGGGGCGGCGTGCCGGCGTATTTCAGCGACGGTAGCCGCA
CCGATTTTGCGCGATCGGATTCGTTCACGCCGCGCTGGGCGCGCGGCGTGGCCGACACCACCAATGCGTTTGCCGGCCTG
ACCCATCGCTTCGACAACGGTGCGCAGCTGCACGTGGAATATTCGCATCAGCGGTTCGAAGCCGATTGGAAGTCGGTGCT
GTTCGGCTACTTCGATTACCCGGACCGCGAGACCGGCCTGGGCCTTTCCAACACTTTTGGCGGGCGCTATCCCGCAATCA
CTGCGCAAAACAGCCTGGATGCCTACCTCAGCGTGCCGTTGACCTGGTGGGGCCGCAATCACGAACTGGTCGCCGGTGCC
ACCTGGATGAACCGCAACGTGCGCAGCTGGTCCAACGGGCCGCAGCCGCCGCAGGTGCTGACGGCCGAAAGCGTCTACGC
CTGGACCGGCAGCATGGCGCAGCCGCAATGGACGCCGCTGGTGAAGGGCGAAGAACGCGACGTGCGCCAGGTGGCCGCCT
ACGCTGCCGGCCGCTTCAGCCTGACCGACGCGCTCACGGCCATCGTCGGCGCACGCGTCACCGACTGGAAGAACACCGAT
CAGCTGGTGCCGGCCAACACCTACGAGCGCCGTGGTCGCACCACGCCGTACGCCGGCCTGATCCTGGACGTGGACGACCA
CCATTCGCTCTACGCCAGCTACACCGGCATCTTCAAGCCGCAAAACAATCGCGACCGCAGCGGGCGCTATCTGGCACCGC
TGGAAGGCAACAGCTACGAGGTCGGTGCCAAGGGCGAGTACCTCGGCGGCCAGCTCAACGCGGCGCTGGCGTTGTTCCGT
ATCGAGCAGGACAACCTGGCGGTCAACGACCCCGGACAACTCGTGCCCGGCACCACCAATCAGGCCTTCCTGGCCGCGAA
GGGCACGGTCAGCCAGGGGGTGGAATTCCAGCTCGATGGGCAGCTTTCCGAGCAGTGGCGGATCGCGTTCGGCTTTGCCC
AGTTCGATGCCAACGATGCCAGCGGCGTCGACGTCAATCCGACCAGCCCGCGTCGCGAGGCTACCCTGTTCGCCAGTTGG
CAGACCGGCCCATGGCGCGTGGGCGGTGGCCTGAGCTGGCAGTCGGCCATCCACGAATTGATGTCCGGGCCACTGGGCAG
CACGCAGCGGCTGACTCAGGGCAGCGTGGTGTTGGCCAACGCCATGGCACGCTACGACATCAACCAGGCATGGTCGGCGC
AGCTCAACGTGCGCAACCTGTTCGACCGCAAGTACTACGCCAACATCGTCTATCAAAGCCAGTTGATCTACGGCGACCCG
CGCGATGTGGAGCTGACGCTGTCCTGGAAGTTCTGA

Upstream 100 bases:

>100_bases
CGCCCCCAGCCAGCAAACGGTACGCGCCTTCCGATGGCGCTGCCGACGCCAGCCTCAATAGCCGTCATCGACGGCCATAC
TCGCTCTTGAGGCTGACCCC

Downstream 100 bases:

>100_bases
ACCTTGCTCCAGACGACAGGCTTTGGCGGCATTCATGCCGCTACCGAGCCTCCACCGACGGACTTACGGCATGTCCCGCT
AGCGGTGAGGGCGGCGCGCA

Product: ferric iron uptake outer membrane protein

Products: NA

Alternate protein names: Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid [H]

Number of amino acids: Translated: 731; Mature: 730

Protein sequence:

>731_residues
MSHRIVPARALTRADIRSPQLPLAYSLLALALACAWPLAAAAQSSTRDPVDLDRLQIEAHRGAATEGSDSYTADVARSST
KLELSLRETPQSVVVVTRQQIVDRNLQSLQDVTDTVAGFNSPTWDTERTYITARGFEVDYYRIDGIPTDYTGDVQQNMAI
YDRVEIIRGANGLTTGAGSPAASIDLVRKHADSDVFTGRVDLSAGRWDRYRGTVDLQSPLNAAGNVRGRVVASDEDKQSF
RDYYSKQSSLFYGIVDADFSDATRGYIGVNKQRNDGRGTTWGGVPAYFSDGSRTDFARSDSFTPRWARGVADTTNAFAGL
THRFDNGAQLHVEYSHQRFEADWKSVLFGYFDYPDRETGLGLSNTFGGRYPAITAQNSLDAYLSVPLTWWGRNHELVAGA
TWMNRNVRSWSNGPQPPQVLTAESVYAWTGSMAQPQWTPLVKGEERDVRQVAAYAAGRFSLTDALTAIVGARVTDWKNTD
QLVPANTYERRGRTTPYAGLILDVDDHHSLYASYTGIFKPQNNRDRSGRYLAPLEGNSYEVGAKGEYLGGQLNAALALFR
IEQDNLAVNDPGQLVPGTTNQAFLAAKGTVSQGVEFQLDGQLSEQWRIAFGFAQFDANDASGVDVNPTSPRREATLFASW
QTGPWRVGGGLSWQSAIHELMSGPLGSTQRLTQGSVVLANAMARYDINQAWSAQLNVRNLFDRKYYANIVYQSQLIYGDP
RDVELTLSWKF

Sequences:

>Translated_731_residues
MSHRIVPARALTRADIRSPQLPLAYSLLALALACAWPLAAAAQSSTRDPVDLDRLQIEAHRGAATEGSDSYTADVARSST
KLELSLRETPQSVVVVTRQQIVDRNLQSLQDVTDTVAGFNSPTWDTERTYITARGFEVDYYRIDGIPTDYTGDVQQNMAI
YDRVEIIRGANGLTTGAGSPAASIDLVRKHADSDVFTGRVDLSAGRWDRYRGTVDLQSPLNAAGNVRGRVVASDEDKQSF
RDYYSKQSSLFYGIVDADFSDATRGYIGVNKQRNDGRGTTWGGVPAYFSDGSRTDFARSDSFTPRWARGVADTTNAFAGL
THRFDNGAQLHVEYSHQRFEADWKSVLFGYFDYPDRETGLGLSNTFGGRYPAITAQNSLDAYLSVPLTWWGRNHELVAGA
TWMNRNVRSWSNGPQPPQVLTAESVYAWTGSMAQPQWTPLVKGEERDVRQVAAYAAGRFSLTDALTAIVGARVTDWKNTD
QLVPANTYERRGRTTPYAGLILDVDDHHSLYASYTGIFKPQNNRDRSGRYLAPLEGNSYEVGAKGEYLGGQLNAALALFR
IEQDNLAVNDPGQLVPGTTNQAFLAAKGTVSQGVEFQLDGQLSEQWRIAFGFAQFDANDASGVDVNPTSPRREATLFASW
QTGPWRVGGGLSWQSAIHELMSGPLGSTQRLTQGSVVLANAMARYDINQAWSAQLNVRNLFDRKYYANIVYQSQLIYGDP
RDVELTLSWKF
>Mature_730_residues
SHRIVPARALTRADIRSPQLPLAYSLLALALACAWPLAAAAQSSTRDPVDLDRLQIEAHRGAATEGSDSYTADVARSSTK
LELSLRETPQSVVVVTRQQIVDRNLQSLQDVTDTVAGFNSPTWDTERTYITARGFEVDYYRIDGIPTDYTGDVQQNMAIY
DRVEIIRGANGLTTGAGSPAASIDLVRKHADSDVFTGRVDLSAGRWDRYRGTVDLQSPLNAAGNVRGRVVASDEDKQSFR
DYYSKQSSLFYGIVDADFSDATRGYIGVNKQRNDGRGTTWGGVPAYFSDGSRTDFARSDSFTPRWARGVADTTNAFAGLT
HRFDNGAQLHVEYSHQRFEADWKSVLFGYFDYPDRETGLGLSNTFGGRYPAITAQNSLDAYLSVPLTWWGRNHELVAGAT
WMNRNVRSWSNGPQPPQVLTAESVYAWTGSMAQPQWTPLVKGEERDVRQVAAYAAGRFSLTDALTAIVGARVTDWKNTDQ
LVPANTYERRGRTTPYAGLILDVDDHHSLYASYTGIFKPQNNRDRSGRYLAPLEGNSYEVGAKGEYLGGQLNAALALFRI
EQDNLAVNDPGQLVPGTTNQAFLAAKGTVSQGVEFQLDGQLSEQWRIAFGFAQFDANDASGVDVNPTSPRREATLFASWQ
TGPWRVGGGLSWQSAIHELMSGPLGSTQRLTQGSVVLANAMARYDINQAWSAQLNVRNLFDRKYYANIVYQSQLIYGDPR
DVELTLSWKF

Specific function: Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid [H]

COG id: COG4773

COG function: function code P; Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=732, Percent_Identity=36.7486338797814, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1787024, Length=211, Percent_Identity=31.2796208530806, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80712; Mature: 80581

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHRIVPARALTRADIRSPQLPLAYSLLALALACAWPLAAAAQSSTRDPVDLDRLQIEAH
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
RGAATEGSDSYTADVARSSTKLELSLRETPQSVVVVTRQQIVDRNLQSLQDVTDTVAGFN
CCCCCCCCCCEEHHHHCCCEEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCC
SPTWDTERTYITARGFEVDYYRIDGIPTDYTGDVQQNMAIYDRVEIIRGANGLTTGAGSP
CCCCCCCCEEEEEECEEEEEEEECCCCCCCCCCHHHCHHHHHHHHHHCCCCCCCCCCCCC
AASIDLVRKHADSDVFTGRVDLSAGRWDRYRGTVDLQSPLNAAGNVRGRVVASDEDKQSF
CHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCCEECCCCCCCCCCCCEEEEECCCHHHHH
RDYYSKQSSLFYGIVDADFSDATRGYIGVNKQRNDGRGTTWGGVPAYFSDGSRTDFARSD
HHHHCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCC
SFTPRWARGVADTTNAFAGLTHRFDNGAQLHVEYSHQRFEADWKSVLFGYFDYPDRETGL
CCCCHHHHCCCHHHHHHHHHHEECCCCCEEEEEECCHHHHHCHHHHHEEECCCCCCCCCC
GLSNTFGGRYPAITAQNSLDAYLSVPLTWWGRNHELVAGATWMNRNVRSWSNGPQPPQVL
CCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCEEEEEEHHHCCCCCCCCCCCCCCCEE
TAESVYAWTGSMAQPQWTPLVKGEERDVRQVAAYAAGRFSLTDALTAIVGARVTDWKNTD
EECEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCEECCCCCC
QLVPANTYERRGRTTPYAGLILDVDDHHSLYASYTGIFKPQNNRDRSGRYLAPLEGNSYE
CCCCCCCHHHCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCEEEECCCCCEE
VGAKGEYLGGQLNAALALFRIEQDNLAVNDPGQLVPGTTNQAFLAAKGTVSQGVEFQLDG
ECCCCCCCCCCCCEEEEEEEEECCCEEECCCCCCCCCCCCCEEEEECCCHHCCCEEEECC
QLSEQWRIAFGFAQFDANDASGVDVNPTSPRREATLFASWQTGPWRVGGGLSWQSAIHEL
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCHHHHHHHH
MSGPLGSTQRLTQGSVVLANAMARYDINQAWSAQLNVRNLFDRKYYANIVYQSQLIYGDP
HCCCCCCCCHHCCCCEEEEHHHHHCCCCCHHCCEEEHHHHHHHHHEEEEEEEEEEEECCC
RDVELTLSWKF
CCEEEEEEECC
>Mature Secondary Structure 
SHRIVPARALTRADIRSPQLPLAYSLLALALACAWPLAAAAQSSTRDPVDLDRLQIEAH
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
RGAATEGSDSYTADVARSSTKLELSLRETPQSVVVVTRQQIVDRNLQSLQDVTDTVAGFN
CCCCCCCCCCEEHHHHCCCEEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCC
SPTWDTERTYITARGFEVDYYRIDGIPTDYTGDVQQNMAIYDRVEIIRGANGLTTGAGSP
CCCCCCCCEEEEEECEEEEEEEECCCCCCCCCCHHHCHHHHHHHHHHCCCCCCCCCCCCC
AASIDLVRKHADSDVFTGRVDLSAGRWDRYRGTVDLQSPLNAAGNVRGRVVASDEDKQSF
CHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCCEECCCCCCCCCCCCEEEEECCCHHHHH
RDYYSKQSSLFYGIVDADFSDATRGYIGVNKQRNDGRGTTWGGVPAYFSDGSRTDFARSD
HHHHCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCC
SFTPRWARGVADTTNAFAGLTHRFDNGAQLHVEYSHQRFEADWKSVLFGYFDYPDRETGL
CCCCHHHHCCCHHHHHHHHHHEECCCCCEEEEEECCHHHHHCHHHHHEEECCCCCCCCCC
GLSNTFGGRYPAITAQNSLDAYLSVPLTWWGRNHELVAGATWMNRNVRSWSNGPQPPQVL
CCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCEEEEEEHHHCCCCCCCCCCCCCCCEE
TAESVYAWTGSMAQPQWTPLVKGEERDVRQVAAYAAGRFSLTDALTAIVGARVTDWKNTD
EECEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCEECCCCCC
QLVPANTYERRGRTTPYAGLILDVDDHHSLYASYTGIFKPQNNRDRSGRYLAPLEGNSYE
CCCCCCCHHHCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCEEEECCCCCEE
VGAKGEYLGGQLNAALALFRIEQDNLAVNDPGQLVPGTTNQAFLAAKGTVSQGVEFQLDG
ECCCCCCCCCCCCEEEEEEEEECCCEEECCCCCCCCCCCCCEEEEECCCHHCCCEEEECC
QLSEQWRIAFGFAQFDANDASGVDVNPTSPRREATLFASWQTGPWRVGGGLSWQSAIHEL
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCHHHHHHHH
MSGPLGSTQRLTQGSVVLANAMARYDINQAWSAQLNVRNLFDRKYYANIVYQSQLIYGDP
HCCCCCCCCHHCCCCEEEEHHHHHCCCCCHHCCEEEHHHHHHHHHEEEEEEEEEEEECCC
RDVELTLSWKF
CCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162465; 8905232; 9278503; 3032906 [H]